STRINGSTRING
A0A1I9LNY7 A0A1I9LNY7 A0A1I9LPZ1 A0A1I9LPZ1 T7P1.21 T7P1.21 A0JPW4_ARATH A0JPW4_ARATH F15H11.18 F15H11.18 ARPC5B ARPC5B T22H22.6 T22H22.6 F22H5.11 F22H5.11 F24O1.20 F24O1.20 RIC3 RIC3 ARPC2B ARPC2B RIC1 RIC1 RIC5 RIC5 F4JCB3_ARATH F4JCB3_ARATH ROPGAP2 ROPGAP2 ARPC4 ARPC4 K18I23.16 K18I23.16 F6A4.20 F6A4.20 FH8 FH8 F19K23.14 F19K23.14 AGP17 AGP17 FH2 FH2 FH3 FH3 ADF9 ADF9 F19F24.21 F19F24.21 ACA7 ACA7 F12F1.5 F12F1.5 CAP1 CAP1 ARPC1A ARPC1A VLN1 VLN1 VLN2 VLN2 ARAC10 ARAC10 CPA-2 CPA-2 FH15A FH15A FH15B FH15B FH21B FH21B ERABP1 ERABP1 TMK1 TMK1 ACT7 ACT7 ACT4 ACT4 ACT11 ACT11 ARAC11 ARAC11 ACT9 ACT9 ROPGEF4 ROPGEF4 ARPC3 ARPC3 C17L7.1 C17L7.1 ARAC1 ARAC1 PRF4 PRF4 PRF5 PRF5 ARAC3 ARAC3 ARAC4 ARAC4 ARAC5 ARAC5 ADF1 ADF1 ADF2 ADF2 Q3E8G1_ARATH Q3E8G1_ARATH QUL2 QUL2 PRF2 PRF2 PRF1 PRF1 PLIM2C PLIM2C ADF8 ADF8 PIR PIR NAP1 NAP1 SCAR4 SCAR4 SCAR2 SCAR2 WAVE5 WAVE5 ADF7 ADF7 SCAR1 SCAR1 Q6NMD9_ARATH Q6NMD9_ARATH PRK2 PRK2 DRP1B DRP1B T24P15.8 T24P15.8 FH9 FH9 PME23 PME23 Q8GXC9_ARATH Q8GXC9_ARATH ROPGAP3 ROPGAP3 CHX28 CHX28 ATL23 ATL23 Q8LDI1_ARATH Q8LDI1_ARATH ICR1 ICR1 ADF12 ADF12 ARPC2A ARPC2A ABC1K1 ABC1K1 T22C5.14 T22C5.14 F14I3.11 F14I3.11 ABIL1 ABIL1 SPK1 SPK1 ICR5 ICR5 ROPGEF1 ROPGEF1 KIN13A KIN13A T8K14.16 T8K14.16 BRK1 BRK1 TIC TIC ACT8 ACT8 F10F5.2 F10F5.2 T15M6.8 T15M6.8 F14O23.2 F14O23.2 RABA6A RABA6A ROPGAP4 ROPGAP4 PRF3 PRF3 SULTR1;3 SULTR1;3 FH16 FH16 ABCG28 ABCG28 RGP5 RGP5 RIC4 RIC4 MJJ3.26 MJJ3.26 F15M7.14 F15M7.14 FIM3 FIM3 FIM5 FIM5 ROPGAP6 ROPGAP6 ROPGAP1 ROPGAP1 KEG KEG RGP2 RGP2 FH17 FH17 SCAR3 SCAR3 ADF10 ADF10 ARP2-2 ARP2-2 Q9LT36_ARATH Q9LT36_ARATH AIP1-2 AIP1-2 ROPGEF8 ROPGEF8 VLN5 VLN5 T5P19_80 T5P19_80 ROPGEF7 ROPGEF7 ADF11 ADF11 F1I16_130 F1I16_130 ROPGEF6 ROPGEF6 ARPC5A ARPC5A T16L24.240 T16L24.240 F16B3.30 F16B3.30 CPB CPB HVA22A HVA22A RABA1I RABA1I MUR4 MUR4 ARP3 ARP3 ARAC6 ARAC6 FH1 FH1 PIP5K6 PIP5K6 GDI1-2 GDI1-2 FIM4 FIM4 ARPC1B ARPC1B STR10 STR10 FH10 FH10 RGP1 RGP1 T28D5.50 T28D5.50 ARAC8 ARAC8 T12G13.30 T12G13.30 STP9 STP9 ARAC9 ARAC9 FH7 FH7 ADF5 ADF5 ADF6 ADF6 ADF4 ADF4 ADF3 ADF3 AIP1-1 AIP1-1
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query proteins and first shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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A0A1I9LNY7Formin-like protein. (160 aa)
A0A1I9LPZ1Uncharacterized protein. (2160 aa)
T7P1.21Hydroxyproline-rich glycoprotein family protein. (944 aa)
A0JPW4_ARATHCytochrome C oxidase assembly protein. (134 aa)
F15H11.18Proline-rich family protein. (176 aa)
ARPC5BActin-related protein 2/3 complex subunit 5B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (135 aa)
T22H22.6Plant invertase/pectin methylesterase inhibitor superfamily protein. (192 aa)
F22H5.11DUF620 family protein (DUF620). (395 aa)
F24O1.20Immunoglobulin E-set superfamily protein. (223 aa)
RIC3CRIB domain-containing protein RIC3; Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Functions as downstream effector of ARAC11/ROP1 to activate calcium signaling that leads to F-actin disassembly associated with exocytosis in the tip of the growing pollen tube. Counteracts the ARAC11/ROP1-RIC4 pathway, which promotes apical F-actin assembly associated with vesicle accumulation, to control actin dynamics and pollen tube apical growth. (220 aa)
ARPC2BActin-related protein 2/3 complex subunit 2B; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development (By similarity). (374 aa)
RIC1CRIB domain-containing protein RIC1; Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Required for cortical microtubule organization. Promotes microtubule bundling and formation of well-ordered microtubule arrays in the neck region of pavement cells. This restricts cell lateral expansion to generate the narrow neck morphology of pavement cells. Its function is inhibited when it interacts with activated ARAC4/ROP2. Represses ARAC4/ROP2 activatio [...] (224 aa)
RIC5CRIB domain-containing protein RIC5; Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Is involved in pollen tube growth regulation through its interaction with ARAC11/ROP1. (193 aa)
F4JCB3_ARATHUncharacterized protein. (640 aa)
ROPGAP2Rho GTPase-activating protein 2; Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. (430 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (169 aa)
K18I23.16Uncharacterized protein. (163 aa)
F6A4.20ABC1 family protein. (1040 aa)
FH8Formin-like protein 8; Might be involved in the organization and polarity of the actin cytoskeleton. Interacts with the barbed end of actin filaments and nucleates actin-filament polymerization in vitro. (760 aa)
F19K23.14F19K23.14 protein. (176 aa)
AGP17Lysine-rich arabinogalactan protein 17; Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death. (185 aa)
FH2Formin-like protein 2; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (894 aa)
FH3Formin-like protein 3; Acts as actin nucleation factor that directs the formation of actin cables and polarized growth in pollen tubes. (785 aa)
ADF9Actin-depolymerizing factor 9; Does not display typical F-actin depolymerizing activity. Exhibits a high ability to stabilize and cross-link actin filaments. Functions as an actin bundling protein with the highest efficiency under acidic conditions. May play a role in the modulation of levels of histone H3 lysine 4 trimethylation and H3 lysine 9 and 14 acetylation at the FLC locus. Belongs to the actin-binding proteins ADF family. (141 aa)
F19F24.21Hydroxyproline-rich glycoprotein family protein. (131 aa)
ACA7Putative calcium-transporting ATPase 7, plasma membrane-type; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles. (1015 aa)
F12F1.5Immunoglobulin E-set superfamily protein. (223 aa)
CAP1Cyclase-associated protein 1; Actin monomer binding protein that accelerates the exchange of ADP for ATP. Regulates the pool of unpolymerized ATP-actin. Key intermediate between actin-depolymerizing factor (ADF)-mediated disassembly and the profilin-based nucleation and elongation machinery. Belongs to the CAP family. (476 aa)
ARPC1AActin-related protein 2/3 complex subunit 1A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (378 aa)
VLN1Villin-1; Binds actin and actin filament bundles in a Ca(2+)/calmodulin-insensitive manner, but is unable to sever, cap, and nucleate actin filament formation in vitro. Does not protect individual filaments from severing by VLN3 (AC O81645). Belongs to the villin/gelsolin family. (909 aa)
VLN2Villin-2; Ca(2+)-regulated actin-binding protein. Involved in actin filaments bundling. Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Required for the construction of actin collars in pollen tubes. Acts redundantly with VLN5 (AC Q9LVC6) to generate thick actin filament bundles and to regulate polarized pollen tube growth. Acts redundantly with VLN3 (AC O81645) to regulate directional organ growth and in sclerenchyma development (respectively). Belongs to the villin/gelsolin family. (976 aa)
ARAC10Rac-like GTP-binding protein ARAC10; Involved in local disassembly of cortical microtubules when associated with ICR5 and KIN13A; Belongs to the small GTPase superfamily. Rho family. (215 aa)
CPA-2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (308 aa)
FH15AFormin-like protein 15a; Belongs to the formin-like family. Class-II subfamily. (405 aa)
FH15BPutative formin-like protein 15b; Belongs to the formin-like family. Class-II subfamily. (352 aa)
FH21BFormin-like protein 21b; Belongs to the formin-like family. Class-II subfamily. (403 aa)
ERABP1Auxin-binding protein 1; Auxin receptor that controls cell elongation and cell division. Involved in embryonic morphogenesis. Acts on the cell cycle, endocycle, cell plate formation, and cell expansion and contributes to the control of auxin-related gene expression. Controls root meristem size and mediates auxin responsiveness. Involved in activation of ROP GTPases in response to auxin and regulation of clathrin-mediated endocytosis in roots. Acts as a positive factor in clathrin recruitment to the plasma membrane, thereby promoting endocytosis. Upon auxin binding, restricts the intern [...] (198 aa)
TMK1Receptor protein kinase TMK1; Transmembrane kinase receptor. Phosphorylates only serine and threonine residues. Involved in auxin signal transduction and cell expansion and proliferation regulation. Forms with ABP1 a cell surface auxin perception complex that activates ROP signaling pathways. Required for auxin promotion of pavement cell interdigitation. Auxin promotes the formation of the ABP1-TMK1 protein complex. (942 aa)
ACT7Actin-7; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins which is involved in the regulation of hormone-induced plant cell proliferation and callus formation. (377 aa)
ACT4Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ACT11Actin-11; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ARAC11Rac-like GTP-binding protein ARAC11; May be involved in cell polarity control during the actin- dependent tip growth of pollen tubes. May regulate callose synthase 1 (CALS1) activity through the interaction with UGT1. (197 aa)
ACT9Putative actin-9; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth; Belongs to the actin family. (366 aa)
ROPGEF4Rop guanine nucleotide exchange factor 4; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. In association with ROPGEF1, acts as specific regulator of ARAC10/ROP11 function in ABA-mediated stomatal closure. (463 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (174 aa)
C17L7.1Uncharacterized protein At4g04980. (724 aa)
ARAC1Rac-like GTP-binding protein ARAC1; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation. (197 aa)
PRF4Profilin-4; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Acts redundantly with PRF5 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth. Functions probably by favoring formin-mediated actin polymerization at pollen tube tips. (134 aa)
PRF5Profilin-5; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Acts redundantly with PRF4 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth. Functions probably by favoring formin-mediated actin polymerization at pollen tube tips. (134 aa)
ARAC3Rac-like GTP-binding protein ARAC3; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation. May be involved in cell polarity control during the actin-dependent tip growth of root hairs. SPK1- dependent activation is required for auxin-mediated inhibition of PIN2 internalization during gravitropic responses. (198 aa)
ARAC4Rac-like GTP-binding protein ARAC4; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (By similarity). May be involved in cell polarity control during the actin-dependent tip growth of root hairs. May regulate a WAVE complex that activates the Arp2/3 complex. (195 aa)
ARAC5Rac-like GTP-binding protein ARAC5; May be involved in cell polarity control during the actin- dependent tip growth of root hairs; Belongs to the small GTPase superfamily. Rho family. (196 aa)
ADF1Actin-depolymerizing factor 1; Actin-depolymerizing protein. Stimulates F-actin depolymerization. Involved in plant development, cell organ expansion and flowering by controlling breakdown of thick actin cables. Severs actin filaments or bundles and promotes actin cytoskeleton disassembly. Binds monomeric actin (G- actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. (139 aa)
ADF2Actin-depolymerizing factor 2; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Required for normal cell growth, plant development, cell organ expansion and flowering. Essential for root-knot nematode infection. (137 aa)
Q3E8G1_ARATHRas-related small GTP-binding family protein. (113 aa)
QUL2Probable methyltransferase PMT5; Belongs to the methyltransferase superfamily. (606 aa)
PRF2Profilin-2; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds G- actin and poly-L-proline with low affinity in vitro. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. May be involved in the cross-talk between vesicular trafficking and the actin cytoskeleton. At high concentrations, profilin prevents the pol [...] (131 aa)
PRF1Profilin-1; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. Coordinates the stochastic dynamic properties of actin filaments by modulating formin- mediated actin nucleation and assembly during axial cell expansion. Binds G-actin and poly-L-proline in vitro. Inhib [...] (131 aa)
PLIM2CLIM domain-containing protein PLIM2c; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. Associates predominantly with long and dynamic actin bundles in the shank of growing pollen tubes. The actin regulatory activities are inhibited by pH > 6.8 and/or high [Ca(2+)]. (213 aa)
ADF8Actin-depolymerizing factor 8; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (140 aa)
PIRProtein PIR; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the ARP2/3 complex. Interacts with the active form of RHO-family GTPases. (1282 aa)
NAP1Protein NAP1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. (1425 aa)
SCAR4Protein SCAR4; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (1170 aa)
SCAR2Protein SCAR2; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. Belongs to the SCAR/WAVE family. (1399 aa)
WAVE5Scar-like domain-containing protein WAVE 5. (2028 aa)
ADF7Actin-depolymerizing factor 7; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Required for pollen tube growth. Promotes turnover of longitudinal actin cables by severing actin filaments in pollen tubes. (137 aa)
SCAR1Protein SCAR1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (821 aa)
Q6NMD9_ARATHProline-rich family protein. (134 aa)
PRK2Pollen receptor-like kinase 2; Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. Phosphorylates ROPGEF1 in its C-terminal region, releasing its auto-inhibition, and thereby activating the ROP1 signaling pathway. May act as a scaffolding protein, recruiting ROPGEF12 to the plasma membrane by binding to its C-terminal domain. Phosphorylates ROPGEF12, releasing its auto- inhibition. (647 aa)
DRP1BDynamin-related protein 1B; Putative microtubule-associated force-producing protein. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (610 aa)
T24P15.8Actin family protein; Belongs to the actin family. (329 aa)
FH9Formin-like protein 9; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (782 aa)
PME23Probable pectinesterase/pectinesterase inhibitor 23; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the N-terminal section; belongs to the PMEI family. (568 aa)
Q8GXC9_ARATHActin cross-linking protein, putative (DUF569). (335 aa)
ROPGAP3Rho GTPase-activating protein 3; Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Involved in secondary wall pattern formation. In association with ROPGEF4, mediates local activation of ARAC10/ROP11 to initiate the distinct pattern of secondary cell walls in xylem cells. (455 aa)
CHX28Cation/H(+) antiporter 28; May operate as a cation/H(+) antiporter. (801 aa)
ATL23E3 ubiquitin-protein ligase ATL23; E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, UBC28 and UBC29 in vitro. (163 aa)
Q8LDI1_ARATHAT3G19900 protein. (222 aa)
ICR1Interactor of constitutive active ROPs 1; Acts as a scaffold, mediating interaction of ROPs with different proteins. Required for primary and adventitious root maintenance, but not for their formation. Promotes the stabilization of ARAC11 on the plasma membrane of the pollen tube initiation site but not the activation of ARAC11. Regulates directionality of polar auxin transport, and is required for the formation of a stable auxin maximum and tip localized auxin gradient during embryogenesis, organogenesis, and meristem activity. Involved in exocytosis and in the recycling of PIN protei [...] (344 aa)
ADF12Actin-depolymerizing factor 12; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (137 aa)
ARPC2AActin-related protein 2/3 complex subunit 2A; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the ARPC2 family. (318 aa)
ABC1K1Protein ACTIVITY OF BC1 COMPLEX KINASE 1, chloroplastic; Kinase that can phosphorylate the tocopherol cyclase VTE1, a key enzyme of tocopherol (vitamin E) metabolism and involved in the recycling of oxidated alpha-tocopherol quinone, possibly stabilizing it at plastoglobules. Regulates also plastoglobule protein composition. Prevents photodamage of chloroplasts under continuous red light, thus working in opposition to ABC1K3. Together with ABC1K1, contributes to plastoglobule (PG) function in prenyl-lipid metabolism, stress response, and thylakoid remodeling. Involved in chlorophyll de [...] (682 aa)
T22C5.14Lipase, putative (DUF620). (433 aa)
F14I3.11BTB/POZ domain-containing protein At1g50280; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (525 aa)
ABIL1Protein ABIL1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity); Belongs to the ABI family. (298 aa)
SPK1Guanine nucleotide exchange factor SPIKE 1; Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Controls actin polymerization via the two heteromeric complexes WAVE and actin-related protein (ARP) 2/3. Involved in cytoskeletal reorganization required for cell shape (e.g. trichome and cotyledon) control and tissue development. Promotes polarized growth and cell-cell adhesion in the leaf epidermis probably by promoting the formation of endoplasmic reticulum (ER) exit site (ERES) and/or trafficking between the [...] (1830 aa)
ICR5Interactor of constitutive active ROPs 5; ROP effector binding specifically activated ROPs and linking them to the microtubule cytoskeleton. Involved in ROP-regulated polar growth. Involved in local disassembly of cortical microtubules when associated with ARAC10 and KIN13A and conversely mediates also the elimination of ARAC10 from the plasma membrane by the cortical microtubules. Accumulates at the plus end of shrinking microtubules. Targets KIN13A to microtubules. (396 aa)
ROPGEF1Rop guanine nucleotide exchange factor 1; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Acts downstream of PRK2 in the control of polarized pollen tube growth by activating ARAC11/ROP1. In association with ROPGEF4, acts as specific regulator of ARAC10/ROP11 function in ABA-mediated stomatal closure. May play a role in the Rac/Rop-signaling pathway that controls ROS-mediated root hair development. (548 aa)
KIN13AKinesin-like protein KIN-13A; Internal motor kinesin involved in trichome morphogenesis. Participates in regulating the formation of Golgi- associated vesicles. Plays a central role in microtubule disassembly via the active ARAC10-ICR5 cascade, which establishes the secondary cell wall pattern in metaxylem vessel cells. Acts redundantly with KIN13B to modulate cell wall synthesis and cell expansion via the THE1 pathway. (794 aa)
T8K14.16C-type mannose receptor (DUF620). (417 aa)
BRK1Protein BRICK 1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. (85 aa)
TICProtein TIME FOR COFFEE; Regulator of normal clock function. Acts in the mid to late night. Contributes to the amplitude of circadian clocks. May act on the transcriptional induction of LATE ELONGATED HYPOCOTYL (LHY). Inhibits MYC2 protein accumulation, acting as a negative factor in the JA- signaling pathway. (1550 aa)
ACT8Actin-8; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
F10F5.2Glutamyl-tRNA (Gln) amidotransferase subunit A (DUF620). (494 aa)
T15M6.8WEB family protein. (284 aa)
F14O23.2Lysine histidine transporter-like 5; Amino acid transporter; Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily. (448 aa)
RABA6ARas-related protein RABA6a; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (233 aa)
ROPGAP4Rho GTPase-activating protein 4; Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Acts as negative feedback regulator in tolerance to oxygen deprivation which requires ARAC4/ROP2. (435 aa)
PRF3Profilin-3; Binds to actin monomers and regulates the organization of the actin cytoskeleton. Can increase the critical concentration (Cc) of actin assembly in vitro. Acts as downstream effector of the hydrogen sulfide signaling to regulate the assembly and depolymerization of F-actin. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (Probable). Binding to the poly-proline motif of formin induces oligomerization of PRF3. PRF3 oligomers inhibit formin-mediated actin assembly to modulate plant immunity triggered by pathog [...] (168 aa)
SULTR1;3Sulfate transporter 1.3; High-affinity H(+)/sulfate cotransporter that mediates the loading of sulfate into the sieve tube. Plays a central role in the regulation of sulfate assimilation. (656 aa)
FH16Formin-like protein 16. (722 aa)
ABCG28ABC transporter G family member 28. (1109 aa)
RGP5Probable UDP-arabinopyranose mutase 5; Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Belongs to the RGP family. (348 aa)
RIC4CRIB domain-containing protein RIC4; Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Required for actin cortical microfilament assembly. Activated by ARAC4/ROP2 to promote the assembly of cortical actin microfilaments required for lobe formation and lateral expansion of pavement cells. Interaction with, and activation by ARAC4/ROP2 is inhibited by RIC1. Functions as downstream effector of ARAC11/ROP1 to promote the assembly of apical F-actin a [...] (153 aa)
MJJ3.26Replication factor C subunit, putative (DUF620). (439 aa)
F15M7.14Lipase (DUF620). (368 aa)
FIM3Fimbrin-3; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (714 aa)
FIM5Fimbrin-5; Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin bundles. Stabilizes and prevents F-actin depolymerization mediated by latrunculin B (LatB). (687 aa)
ROPGAP6Rho GTPase-activating protein 6; Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. (827 aa)
ROPGAP1Rho GTPase-activating protein 1; Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. (466 aa)
KEGE3 ubiquitin-protein ligase KEG; Mediates E2-dependent protein ubiquitination. Acts as a negative regulator of abscisic acid signaling. Required for ABI5 degradation, by mediating its ubiquitination. Together with EDR1, may regulate endocytic trafficking and/or the formation of signaling complexes on trans-Golgi network (TGN)/ early endosome (EE) vesicles during stress responses. (1625 aa)
RGP2UDP-arabinopyranose mutase 2; UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP- Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Proba [...] (360 aa)
FH17Formin-like protein 17; Belongs to the formin-like family. Class-II subfamily. (495 aa)
SCAR3Protein SCAR3; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (1020 aa)
ADF10Actin-depolymerizing factor 10; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (140 aa)
ARP2-2Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, [...] (389 aa)
Q9LT36_ARATHProline-rich family protein. (134 aa)
AIP1-2Actin-interacting protein 1-2; Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins. (609 aa)
ROPGEF8Rho guanine nucleotide exchange factor 8; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Active as homodimer. (523 aa)
VLN5Villin-5; Major actin filament stabilizing factor and regulator of actin dynamics. Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Required for the construction of actin collars in pollen tubes. Acts synergistically with VLN2 (AC O81644) to regulate polarized pollen tube growth. Belongs to the villin/gelsolin family. (962 aa)
T5P19_80Import inner membrane translocase subunit. (434 aa)
ROPGEF7Rop guanine nucleotide exchange factor 7; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. In postembryonic roots, modulates root stem cell maintenance by regulating the expression of PLT1 and PLT2, which are key transcription factors that mediate the patterning of the root stem cell niche. May connect RopGEF-regulated Rac/Rop signaling and auxin- dependent PLT-regulated root pattern formation. (546 aa)
ADF11Putative actin-depolymerizing factor 11; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (133 aa)
F1I16_130Replication factor C subunit, putative (DUF620). (438 aa)
ROPGEF6Rop guanine nucleotide exchange factor 6; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. (579 aa)
ARPC5AActin-related protein 2/3 complex subunit 5A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (132 aa)
T16L24.240IQ-domain 13. (517 aa)
F16B3.30Glycine-rich protein family. (217 aa)
CPBProbable F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (256 aa)
HVA22AHVA22-like protein a. (177 aa)
RABA1IRas-related protein RABA1i; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (218 aa)
MUR4UDP-arabinose 4-epimerase 1; Acts as a UDP-D-xylose 4-epimerase but lacks both UDP-D- glucose and UDP-D-glucuronic acid 4-epimerase activities in vitro. Belongs to the NAD(P)-dependent epimerase/dehydratase family. (419 aa)
ARP3Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, [...] (427 aa)
ARAC6Rac-like GTP-binding protein ARAC6; May be involved in cell polarity control during the actin- dependent tip growth of pollen tubes; Belongs to the small GTPase superfamily. Rho family. (197 aa)
FH1Formin-like protein 1; Might be involved in the organization and polarity of the actin cytoskeleton. Involved in polar pollen cell growth process by maintaining tip-focused cell membrane expansion for the polar extension of pollen tubes; Belongs to the formin-like family. Class-I subfamily. (1051 aa)
PIP5K6Phosphatidylinositol 4-phosphate 5-kinase 6. (715 aa)
GDI1-2Rho GDP-dissociation inhibitor 1; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. (240 aa)
FIM4Fimbrin-4; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (652 aa)
ARPC1BActin-related protein 2/3 complex subunit 1B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the WD repeat ARPC1 family. (378 aa)
STR10Rhodanese-like domain-containing protein 10. (214 aa)
FH10Formin-like protein 10; Might be involved in the organization and polarity of the actin cytoskeleton. (841 aa)
RGP1UDP-arabinopyranose mutase 1; UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP- Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Proba [...] (357 aa)
T28D5.50KOW domain-containing protein. (141 aa)
ARAC8Rac-like GTP-binding protein ARAC8; Acts as a negative regulator of abscisic acid (ABA) responses; Belongs to the small GTPase superfamily. Rho family. (208 aa)
T12G13.30P-loop containing nucleoside triphosphate hydrolases superfamily protein. (127 aa)
STP9Sugar transport protein 9; Mediates an active uptake of hexoses, probably by sugar/hydrogen symport. Mostly transports glucose, and barely galactose, xylose and mannose; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (517 aa)
ARAC9Rac-like GTP-binding protein ARAC9; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation. (209 aa)
FH7Formin-like protein 7; Might be involved in the organization and polarity of the actin cytoskeleton. (929 aa)
ADF5Actin-depolymerizing factor 5; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (143 aa)
ADF6Actin-depolymerizing factor 6; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (146 aa)
ADF4Actin-depolymerizing factor 4; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Contributes to the stochastic dynamic turnover of actin filaments. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Involved in resistance triggered by the effector AvrPphB of Pseudomonas syringae pv tomato (Pst). May modulate the AvrPphB-RPS5-mediated defense signal transduction pathway. During AvrPphB-triggered resistance signaling pathway, involved in the control of MPK3 an [...] (139 aa)
ADF3Actin-depolymerizing factor 3; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (139 aa)
AIP1-1Actin-interacting protein 1-1; Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins. (611 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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