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WRKY22 | WRKY transcription factor 22; Transcription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor- responsive cis-acting element. Activates WRKY 29, SIRK and its own promoters; Belongs to the WRKY group II-e family. (298 aa) | ||||
ANP1 | Mitogen-activated protein kinase kinase kinase ANP1; May be involved in an oxidative stress-mediated signaling cascade that phosphorylates downstream MAP kinases MPK3 and MPK6. May suppress auxin signaling that promotes cell cycle. Functionally redundant to ANP2 and ANP3 in the positive regulation of cytokinesis. (666 aa) | ||||
ANP3 | Mitogen-activated protein kinase kinase kinase 3; Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule- associated proteins such as MAP65-1; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (651 aa) | ||||
MPK14 | Mitogen-activated protein kinase 14; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) | ||||
dl3430w | Protein kinase superfamily protein. (364 aa) | ||||
MKK3 | Mitogen-activated protein kinase kinase 3; MKK3-MPK6 module plays an important role in the jasmonate signal transduction pathway through the negative regulation of MYC2/JIN1 expression. Activates by phosphorylation the downstream MPK6, MPK7 and MPK8. MKK3-MPK7 module acts as a positive regulator of PR1 gene expression. MKK3-MPK8 module negatively regulates ROS accumulation through controlling expression of the RBOHD gene. Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses. Activator of the C group MAP kinases. [...] (520 aa) | ||||
MKK4 | Mitogen-activated protein kinase kinase 4; Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the [...] (366 aa) | ||||
MAPKKK17 | Mitogen-activated protein kinase kinase kinase 17; Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses. Triggers MPK7 activation in a MKK3-dependent manner. Mediates the ABA- dependent activation of the MKK3-MPK7 module. (372 aa) | ||||
MEKK2 | Mitogen-activated protein kinase kinase kinase 9; Triggers SUMM2-mediated immune responses, including cell death and defense responses. Probably inhibited by the MEKK1-MKK1/ MKK2-MPK4 kinase cascade to adjust plant defense. Seems to contribute in transducing external glutamate (L-Glu) signal that elicits large-scale changes in root architecture. (773 aa) | ||||
PTP1 | Protein-tyrosine-phosphatase PTP1; Protein-tyrosine-phosphatase that dephosphorylates and probably inhibits MPK6 in non-oxidative stress conditions. In association with MKP1, represses salicylic acid (SA) and camalexin biosynthesis, thus modulating defense response. May also repress MPK3. Dephosphorylates and inactivates MPK4 in vitro. (340 aa) | ||||
SUMM2 | Disease resistance protein SUMM2; Disease resistance protein that mediates defense responses against the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000, and the virulent oomycete Hyaloperonospora arabidopsidis isolate Noco2. Becomes active when the MEKK1-MKK1-MKK2-MPK4 kinase cascade is disrupted by the microbial effector hopAI1. Does not seem to be required for the activation of MPK4 by flg22, or flg22-induced up- regulation of PAD3. Functions downstream of MEKK2/SUMM1 in immune responses, including cell death and defense responses. (894 aa) | ||||
MEKK1 | Mitogen-activated protein kinase kinase kinase 1; The MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in the cold and salinity stress-mediated MAP kinase signaling cascade (MEKK1, MKK1/MKK2 and MPK4/MPK6). Activates by phosphorylation the downstream [...] (608 aa) | ||||
MPK2 | Mitogen-activated protein kinase 2. (376 aa) | ||||
MPK3 | Mitogen-activated protein kinase 3; Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Mediates the phosphorylation of VIP1 and subsequent stress genes transcription in response to Agrobacterium. MKK9-M [...] (370 aa) | ||||
MPK4 | Mitogen-activated protein kinase 4; The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. Essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during male-specific meiosis. Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65- 1. Involved in root hair development process. Negative regulator of systemic acquired resistance (SAR) and salicylic acid- (SA) mediated defense response. Requi [...] (376 aa) | ||||
MPK6 | Mitogen-activated protein kinase 6; Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Phosphorylates 1-aminocyclopropane-1- carboxylic acid synthases (ACS2 and ACS6) and may be involved in the regulati [...] (395 aa) | ||||
MPK7 | Mitogen-activated protein kinase 7; MKK3-MPK7 module acts as a positive regulator of PR1 gene expression; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa) | ||||
IBR5 | Protein-tyrosine-phosphatase IBR5; Required for the transduction of auxin and abscisic acid (ABA) signaling pathways. Dephosphorylates and inactivates the MAP kinase MPK12. (257 aa) | ||||
MPK12 | Mitogen-activated protein kinase 12; Negative regulator of the auxin transduction signaling pathway. Involved in stomatal movement regulation by phosphorylating and repressing HT1 and HT1-mediated GHR1 phosphorylation. Required for CO(2)- mediated stomatal movements (e.g. closure). Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (372 aa) | ||||
KIN7B | Kinesin-like protein KIN-7B; Probable plus end-directed motor protein that functions in the NACK-PQR (ANP3-MKK6-MPK4) MAP kinase signaling pathway, which is essential for somatic cell cytokinesis, especially for the cell-plate formation and its expansion. May regulate the activity and the localization of ANP3, probably by association through the non-catalytic region of the kinase. Functionally redundant with NACK1 and essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during microgametogenesis and megagametogenesis. (938 aa) | ||||
MKK5 | Mitogen-activated protein kinase kinase 5; Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the [...] (348 aa) | ||||
MKK1 | Mitogen-activated protein kinase kinase 1; MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H(2)O(2) production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination. (354 aa) | ||||
MPK18 | Mitogen-activated protein kinase 18; Mitogen-activated protein kinase (MAPK) that is specifically regulated by PHS1 and mediates signaling that regulates cortical microtubule functions, maybe through regulation of microtubule dynamic instability. (615 aa) | ||||
MKP1 | Protein-tyrosine-phosphatase MKP1; Protein-tyrosine-phosphatase that acts as a negative regulator of MPK6 and MPK3 signaling by dephosphorylating and repressing MPK6 and MPK3. Modulates defense response by repressing salicylic acid (SA) production, camalexin biosynthesis and SNC1- mediated responses. Acts as a negative regulator of MPK6-mediated pathogen-associated molecular pattern (PAMP) responses, including MPK6 and MPK3 activation, accumulation of extracellular reactive oxygen species and inhibition of seedling growth. Involved in UV-B stress tolerance. May be involved in salt and [...] (784 aa) | ||||
YDA | Mitogen-activated protein kinase kinase kinase YODA; Functions in a MAP kinase cascade that acts as a molecular switch to regulate the first cell fate decisions in the zygote and the early embryo. Promotes elongation of the zygote and development of its basal daughter cell into the extra-embryonic suspensor. In stomatal development, acts downstream of the LRR receptor TMM, but upstream of the MKK4/MKK5-MPK3/MPK6 module to regulate stomatal cell fate before the guard mother cell (GMC) is specified. Plays a central role in both guard cell identity and pattern formation. This MAPK cascade [...] (883 aa) | ||||
MAPKKK19 | Mitogen-activated protein kinase kinase kinase 19; Belongs to the protein kinase superfamily. (344 aa) | ||||
MKK6 | Mitogen-activated protein kinase kinase 6; The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. MKK6-MPK13 module positively regulates lateral root formation. Phosphorylates and activates MPK4. Activates MPK5 and MPK13 in vitro. (356 aa) | ||||
MKK9 | Mitogen-activated protein kinase kinase 9; MKK9-MPK3/MPK6 module phosphorylates and activates EIN3, leading to the promotion of EIN3-mediated transcription in ethylene signaling. Autophosphorylates and also phosphorylates MPK3 and MPK6. Plays an important role in ethylene and camalexin biosynthesis and in salt stress response. MKK9-MPK6 module positively regulates leaf senescence. (310 aa) | ||||
ANP2 | Mitogen-activated protein kinase kinase kinase 2; Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule- associated proteins such as MAP65-1. (651 aa) | ||||
MKK7 | Mitogen-activated protein kinase kinase 7; May function as a negative regulator of polar auxin transport. Positively regulates plant basal and systemic acquired resistance (SAR). Activates MPK3 and MPK6 in vitro. (307 aa) | ||||
MPK13 | Mitogen-activated protein kinase 13; MKK6-MPK13 module positively regulates lateral root formation; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa) | ||||
ATN1 | Nearly identical to protein kinase ATN1; Belongs to the protein kinase superfamily. (356 aa) | ||||
MPK10 | Mitogen-activated protein kinase 10. (393 aa) | ||||
MKK8 | Mitogen-activated protein kinase kinase 8; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. (309 aa) | ||||
DSPTP1B | Dual specificity protein phosphatase 1B; Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Prevents biotic and abiotic stress responses, including ozone, oxidative stress and pathogen attacks; represses MAPK activities during hypersensitive response to limit the spread of the HR response after infection by necrotrophic pathogen such as Botrytis cinerea. May be also involved in ABA and salt responses. Dephosphorylates MPK3 and MPK6. (167 aa) | ||||
MKK2 | Mitogen-activated protein kinase kinase 2; MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Plays a role in abiotic stress tolerance and plant disease resistance through activation of MPK4 and MPK6 by phosphorylation. Acts redundantly with MKK1. (363 aa) | ||||
F11C1_150 | Mitogen-activated protein kinase kinase kinase 20. (342 aa) | ||||
DSPTP1 | Dual specificity protein phosphatase 1; Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Dephosphorylates MPK4 in vitro. (198 aa) | ||||
MAPKKK18 | Mitogen-activated protein kinase kinase kinase 18; Component of the abscisic acid (ABA) signaling pathway that acts as ABA signal transducer in the context of abiotic stresses. Triggers MPK1, MPK2, MPK7 and MPK14 activation in a MKK3-dependent manner and MPK6 activation in a MKK3-independent manner. Mediates the ABA-dependent activation of the MKK3-MPK7 module. Positive regulator of ABA responses leading to the induction of gene expression (e.g. RD29B and RAB18) and involved in various responses including stomatal development, stomatal movement, inhibition of germination and root growt [...] (339 aa) |