(5 nodes) Spermidine biosynthesis network (Arabidopsis thaliana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPDSYN2	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family. (340 aa)
	SAM2	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. (393 aa)
	SAMDC3	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development. (349 aa)
	SAMDC2	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family. (362 aa)
	SPDSYN1	Spermidine synthase 1. (334 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SAM2	SAMDC2	P17562	Q9S7T9	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family.	0.970
SAM2	SAMDC3	P17562	Q9LSU6	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development.	0.966
SAM2	SPDSYN1	P17562	Q9ZUB3	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	Spermidine synthase 1.	0.835
SAM2	SPDSYN2	P17562	O48661	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	0.855
SAMDC2	SAM2	Q9S7T9	P17562	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family.	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	0.970
SAMDC2	SPDSYN1	Q9S7T9	Q9ZUB3	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family.	Spermidine synthase 1.	0.996
SAMDC2	SPDSYN2	Q9S7T9	O48661	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family.	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	0.995
SAMDC3	SAM2	Q9LSU6	P17562	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development.	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	0.966
SAMDC3	SPDSYN1	Q9LSU6	Q9ZUB3	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development.	Spermidine synthase 1.	0.996
SAMDC3	SPDSYN2	Q9LSU6	O48661	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development.	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	0.995
SPDSYN1	SAM2	Q9ZUB3	P17562	Spermidine synthase 1.	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	0.835
SPDSYN1	SAMDC2	Q9ZUB3	Q9S7T9	Spermidine synthase 1.	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family.	0.996
SPDSYN1	SAMDC3	Q9ZUB3	Q9LSU6	Spermidine synthase 1.	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development.	0.996
SPDSYN1	SPDSYN2	Q9ZUB3	O48661	Spermidine synthase 1.	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	0.959
SPDSYN2	SAM2	O48661	P17562	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.	0.855
SPDSYN2	SAMDC2	O48661	Q9S7T9	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	S-adenosylmethionine decarboxylase 2 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development; Belongs to the eukaryotic AdoMetDC family.	0.995
SPDSYN2	SAMDC3	O48661	Q9LSU6	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	S-adenosylmethionine decarboxylase 1 alpha chain; Essential for biosynthesis of the polyamines spermidine and spermine. Essential for polyamine homeostasis, and normal plant embryogenesis, growth and development.	0.995
SPDSYN2	SPDSYN1	O48661	Q9ZUB3	Spermidine synthase 2; Belongs to the spermidine/spermine synthase family.	Spermidine synthase 1.	0.959