STRINGSTRING
NAC010 NAC010 NAC026 NAC026 NAC073 NAC073 MYB32 MYB32 XCP1 XCP1 LBD30 LBD30 MYB7 MYB7 MYB52 MYB52 NAC043 NAC043 NAC104 NAC104 BHLH48 BHLH48 MYB61 MYB61 WRKY12 WRKY12 MYB85 MYB85 MYB83 MYB83 MYB20 MYB20 NAC030 NAC030 K24M7.12 K24M7.12 NAC007 NAC007 MYB54 MYB54 NAC083 NAC083 MYB46 MYB46 NAC066 NAC066 MYB58 MYB58 NAC037 NAC037 MYB42 MYB42 MYB26 MYB26 MYB43 MYB43 AtMYB103 AtMYB103 ATMYB69 ATMYB69
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NAC010NAC domain-containing protein 10; Transcriptional activator that plays a regulatory role in the development of secondary cell wall fibers. Is a direct target of SND1. (314 aa)
NAC026NAC domain-containing protein 26; Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'- (T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls. Belongs to the plant vascular related NAC-domain protein family. (394 aa)
NAC073NAC domain-containing protein 73; Transcriptional activator that plays a regulatory role in the development of secondary cell wall fibers. Involved in the regulation of cellulose and hemicellulose biosynthetic genes as well as of genes involved in lignin polymerization and signaling. Is not a direct target of SND1. (305 aa)
MYB32Transcription factor MYB32. (274 aa)
XCP1Cysteine protease XCP1; Cysteine protease involved in xylem tracheary element (TE) autolysis during xylogenesis in roots. Participates in micro autolysis within the intact central vacuole before mega autolysis is initiated by tonoplast implosion. (355 aa)
LBD30LOB domain-containing protein 30; Involved in the positive regulation of tracheary element (TE) differentiation. Involved in a positive feedback loop that maintains or promotes NAC030/VND7 expression that regulates TE differentiation- related genes; Belongs to the LOB domain-containing protein family. (228 aa)
MYB7Transcription factor MYB7; Transcription factor involved in the negative regulation of flavonol biosynthesis. Represses the early phenylpropanoid genes, phenylalanine ammonia-lyase (PAL), cinnamate 4-hydroxylase (C4H) and 4- coumarate-CoA ligase (4CL), as well as the flavonoid-specific genes, flavonoid 3'-hydroxylase (F3'H) and dihydroflavonol 4-reductase (DFR). Plays a role in seed germination inhibition. Negatively regulates the expression of the abscisic acid (ABA) signaling transcription factor ABI5 in seeds. (269 aa)
MYB52Transcription factor MYB52; Transcription factor that confers sensitivity to abscisic acid (ABA) and salt, but tolerance to drought. Regulates secondary cell wall (SCW) biosynthesis, especially in interfascicular and xylary fibers. (249 aa)
NAC043NAC domain-containing protein 43; Transcription activator of genes involved in biosynthesis of secondary walls. Together with NST2 and NST3, required for the secondary cell wall thickening of sclerenchymatous fibers, secondary xylem (tracheary elements), and of the anther endocethium, which is necessary for anther dehiscence. May also regulate the secondary cell wall lignification of other tissues. (365 aa)
NAC104NAC domain-containing protein 104; Probable transcription factor that influences tracheary elements and xylem development by negatively regulating secondary cell wall fiber synthesis and programmed cell death. (187 aa)
BHLH48Transcription factor bHLH48. (327 aa)
MYB61Transcription factor MYB61; Transcription factor that coordinates a small network of downstream target genes required for several aspects of plant growth and development, such as xylem formation and xylem cell differentiation, and lateral root formation. Regulates a specific set of target genes by binding DNA to the AC cis- element 5'-ACCTAC-3'. Functions as a transcriptional regulator of stomatal closure. Plays a role the regulation of stomatal pore size independently of abscisic acid (ABA). Required for seed coat mucilage deposition during the development of the seed coat epidermis. [...] (366 aa)
WRKY12Probable WRKY transcription factor 12; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity); Belongs to the WRKY group II-c family. (218 aa)
MYB85Myb family transcription factor. (266 aa)
MYB83Transcription factor MYB83; Transcription factor that acts as molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1 and its close homologs, including NAC043/NST1, NAC066/NST2, NAC101/VND6 and NAC030/VND7. Is required for functional expression of a number of secondary wall-associated transcription factors and secondary wall biosynthetic genes involved in cellulose, xylan and lignin synthesis. Functions redundantly with MYB46 in the transcriptional regulatory cascade leading to secondary wall form [...] (343 aa)
MYB20Transcription factor MYB20; Transcription factor that acts as positive regulator of abscisic acid (ABA) signaling in response to salt stress. Acts as negative regulator ABI1, ABI2 and PP2CA, which are protein phosphatases 2C acting as negative regulator of ABA signaling. Binds to the DNA specific sequence and core element 5'-ACGT-3' found in the promoters of ABI1 and PP2CA to negatively regulate their expression during ABA- dependent salt stress response. (282 aa)
NAC030NAC domain-containing protein 30; Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'- (T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression. Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB10 [...] (324 aa)
K24M7.12VASCULAR-RELATED NAC-DOMAIN 6. (268 aa)
NAC007NAC domain-containing protein 7; Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'- (T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls. (395 aa)
MYB54Transcription factor MYB54; Transcription factor that regulates secondary cell wall (SCW) biosynthesis, especially in interfascicular and xylary fibers. (243 aa)
NAC083NAC domain-containing protein 83; Transcriptional repressor that negatively regulates the expression of genes involved in xylem vessel formation. Represses the transcriptional activation activity of NAC030/VND7, which regulates protoxylem vessel differentiation by promoting immature xylem vessel- specific genes expression. Transcriptional activator that regulates the COLD-REGULATED (COR15A and COR15B) and RESPONSIVE TO DEHYDRATION (LTI78/RD29A and LTI65/RD29B) genes by binding directly to their promoters. Mediates signaling crosstalk between salt stress response and leaf aging process. [...] (252 aa)
MYB46Transcription factor MYB46; Transcription activator. Involved in the regulation of secondary wall biosynthesis in fibers and vessels. Transcription activator of the mannan synthase CSLA9 that recognizes and binds to the DNA consensus sequence 5'-[AG][GT]T[AT]GGT[GA]-3' cis- regulatory element of CSLA9 promoter. Transcription factor that acts as molecular switch in the NAC012/SND1-mediated transcriptional network regulating secondary wall biosynthesis. Is directly activated by NAC012/SND1. Functions redundantly with MYB83 in the transcriptional regulatory cascade leading to secondary wa [...] (280 aa)
NAC066NAC domain-containing protein 66; Transcription activator of genes involved in biosynthesis of secondary walls. Together with NST1, required for the secondary cell wall thickening of the anther endocethium, which is necessary for anther dehiscence. May also regulate the secondary cell wall lignification of other tissues such as tracheary elements. (334 aa)
MYB58Transcription factor MYB58; Transcriptional activator that binds DNA to the AC cis- elements 5'-ACCTACC-3', 5'-ACCAACC-3' and 5'-ACCTAAC-3' of promoters and specifically activates lignin biosynthetic genes during secondary wall formation mediated by SND1. (274 aa)
NAC037NAC domain-containing protein 37; Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'- (T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls. (365 aa)
MYB42Putative transcription factor. (286 aa)
MYB26Transcription factor MYB26; Probable transcription factor that regulates lignified secondary cell wall thickening of the anther endocethium, which is necessary for anther dehiscence. May play a role in specifying early endothecial cell development by regulating a number of genes linked to secondary thickening such as NST1 and NST2. Acts upstream of the lignin biosynthesis pathway. (367 aa)
MYB43Putative transcription factor. (327 aa)
AtMYB103Putative MYB family transcription factor; 19087-20744. (370 aa)
ATMYB69Putative transcription factor. (250 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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