(11 nodes) Mixed, incl. ER body, and Coumarin metabolic process network (Arabidopsis thaliana)

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Your Input:
	MEB2	Membrane protein of ER body 2; May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity. Not essential for the accumulation of ER body components, including PYK10. Belongs to the CCC1 family. (550 aa)
	PBP2	PYK10-binding protein 2; Polymerizer-type lectin that may facilitate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23. (296 aa)
	PBP1	PYK10-binding protein 1; Inhibitor-type lectin that may regulate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23. (298 aa)
	JAL22	Jacalin-related lectin 22; Inhibitor-type lectin that may regulate the correct polymerization and activation of BGLU23/PYK10 upon tissue damage. (458 aa)
	NAI1	Transcription factor NAI1; Transcription activator that regulates the expression of at least NAI2, PYK10 and PBP1. Required for and mediates the formation of endoplasmic reticulum bodies (ER bodies). Involved in the symbiotic interactions with the endophytes of the Sebacinaceae fungus family, such as Piriformospora indica and Sebacina. (320 aa)
	MEB1	Membrane protein of ER body 1; May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity. Not essential for the accumulation of ER body components, including PYK10. (611 aa)
	BGLU21	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. (524 aa)
	BGLU22	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family. (524 aa)
	ML3	MD-2-related lipid-recognition protein 3; May be involved in herbivory-mediated responses. May play a role in herbivory-associated molecular pattern (HAMP) recognition. May function is jasmonate (JA) signaling in response to HAMP. May play a role in defense response against the pathogens Altenaria brassicicola and Pseudomonas syringae. (164 aa)
	NAI2	TSA1-like protein; Responsible for the ER body formation. Regulates the number and shape of the ER bodies and the accumulation of PYK10 in ER bodies, but is not involved in the expression of PYK10. (772 aa)
	BGLU23	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction. (524 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGLU21	BGLU22	Q9C525	Q9C8Y9	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	0.919
BGLU21	BGLU23	Q9C525	Q9SR37	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction.	0.707
BGLU21	JAL22	Q9C525	O80950	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	Jacalin-related lectin 22; Inhibitor-type lectin that may regulate the correct polymerization and activation of BGLU23/PYK10 upon tissue damage.	0.690
BGLU21	MEB1	Q9C525	Q8W4P8	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	Membrane protein of ER body 1; May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity. Not essential for the accumulation of ER body components, including PYK10.	0.751
BGLU21	MEB2	Q9C525	F4KFS7	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	Membrane protein of ER body 2; May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity. Not essential for the accumulation of ER body components, including PYK10. Belongs to the CCC1 family.	0.801
BGLU21	NAI1	Q9C525	Q8S3F1	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	Transcription factor NAI1; Transcription activator that regulates the expression of at least NAI2, PYK10 and PBP1. Required for and mediates the formation of endoplasmic reticulum bodies (ER bodies). Involved in the symbiotic interactions with the endophytes of the Sebacinaceae fungus family, such as Piriformospora indica and Sebacina.	0.809
BGLU21	NAI2	Q9C525	Q9LSB4	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	TSA1-like protein; Responsible for the ER body formation. Regulates the number and shape of the ER bodies and the accumulation of PYK10 in ER bodies, but is not involved in the expression of PYK10.	0.818
BGLU21	PBP1	Q9C525	O04314	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	PYK10-binding protein 1; Inhibitor-type lectin that may regulate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23.	0.844
BGLU21	PBP2	Q9C525	O04313	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	PYK10-binding protein 2; Polymerizer-type lectin that may facilitate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23.	0.917
BGLU22	BGLU21	Q9C8Y9	Q9C525	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	0.919
BGLU22	BGLU23	Q9C8Y9	Q9SR37	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction.	0.827
BGLU22	JAL22	Q9C8Y9	O80950	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	Jacalin-related lectin 22; Inhibitor-type lectin that may regulate the correct polymerization and activation of BGLU23/PYK10 upon tissue damage.	0.741
BGLU22	NAI1	Q9C8Y9	Q8S3F1	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	Transcription factor NAI1; Transcription activator that regulates the expression of at least NAI2, PYK10 and PBP1. Required for and mediates the formation of endoplasmic reticulum bodies (ER bodies). Involved in the symbiotic interactions with the endophytes of the Sebacinaceae fungus family, such as Piriformospora indica and Sebacina.	0.800
BGLU22	NAI2	Q9C8Y9	Q9LSB4	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	TSA1-like protein; Responsible for the ER body formation. Regulates the number and shape of the ER bodies and the accumulation of PYK10 in ER bodies, but is not involved in the expression of PYK10.	0.776
BGLU22	PBP1	Q9C8Y9	O04314	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	PYK10-binding protein 1; Inhibitor-type lectin that may regulate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23.	0.835
BGLU22	PBP2	Q9C8Y9	O04313	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	PYK10-binding protein 2; Polymerizer-type lectin that may facilitate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23.	0.926
BGLU23	BGLU21	Q9SR37	Q9C525	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction.	Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates.	0.707
BGLU23	BGLU22	Q9SR37	Q9C8Y9	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction.	Beta-glucosidase 22; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside. No activity with DIMBOA-glucoside, pNP-glucoside, oNP- glucoside and sinigrin as substrates; Belongs to the glycosyl hydrolase 1 family.	0.827
BGLU23	JAL22	Q9SR37	O80950	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction.	Jacalin-related lectin 22; Inhibitor-type lectin that may regulate the correct polymerization and activation of BGLU23/PYK10 upon tissue damage.	0.812
BGLU23	MEB1	Q9SR37	Q8W4P8	Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction.	Membrane protein of ER body 1; May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity. Not essential for the accumulation of ER body components, including PYK10.	0.905