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PAB3 PAB3 TOPP8 TOPP8 PIRL7 PIRL7 PIRL3 PIRL3 IAN4 IAN4 MKP6.29 MKP6.29
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAB3Polyadenylate-binding protein 3; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Inhibits the polyadenylated RNA degradation by the Rrp41p 3'-->5' exonuclease in vitro. Binds with the 5'UTRs of PAB2, PAB3 and with a lower affinity with the 5'UTR of PAB5. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
TOPP8Serine/threonine-protein phosphatase PP1 isozyme 8; Serine/threonine-protein phosphatase that possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro. Belongs to the PPP phosphatase family. PP-1 subfamily. (324 aa)
PIRL7Plant intracellular Ras-group-related LRR protein 7; Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction. Belongs to the SHOC2 family. (373 aa)
PIRL3Plant intracellular Ras-group-related LRR protein 3; Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction. Belongs to the SHOC2 family. (464 aa)
IAN4Immune-associated nucleotide-binding protein 4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. (326 aa)
MKP6.29F-box protein At3g17710. (368 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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