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A0A1P8B457 A0A1P8B457 K19B1.7 K19B1.7 F20P5.28 F20P5.28 CATHB1 CATHB1 F28N24.18 F28N24.18 F4I2N3_ARATH F4I2N3_ARATH T17M13.18 T17M13.18 CYP704A1 CYP704A1 F4IXJ0_ARATH F4IXJ0_ARATH RDL6 RDL6 T14G11.20 T14G11.20 CYP21-1 CYP21-1 AAC1 AAC1 RD19A RD19A RD21A RD21A ALPHA-VPE ALPHA-VPE XBCP3 XBCP3 bVPE bVPE GAMMA-VPE GAMMA-VPE F27J15.6 F27J15.6 CYP59 CYP59 F28N24.20 F28N24.20 MLE2.7 MLE2.7 ALEU ALEU CYP21-2 CYP21-2 ER-ANT1 ER-ANT1 CYP19-4 CYP19-4 MARD1 MARD1 F18N11.70 F18N11.70 CATHB2 CATHB2 CYP21-3 CYP21-3 CATHB3 CATHB3 F19C24.6 F19C24.6 PP2A4-2 PP2A4-2 DRG2 DRG2 TZF5 TZF5 PM-ANT PM-ANT RD21B RD21B AMC9 AMC9 dVPE dVPE DRG1 DRG1 RDL2 RDL2 RD21C RD21C T32M21_20 T32M21_20 SFC1 SFC1 SERPIN1 SERPIN1 RBG1 RBG1 F11A3.17 F11A3.17 PIN1-2 PIN1-2 RD19C RD19C DRG3 DRG3 F10A12.10 F10A12.10
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1P8B457Leukocyte receptor cluster-like protein. (252 aa)
K19B1.7RING/FYVE/PHD zinc finger superfamily protein. (320 aa)
F20P5.28Structural polyprotein. (205 aa)
CATHB1Cathepsin B-like protease 1; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB2 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...] (379 aa)
F28N24.18Cysteine proteinases superfamily protein; Belongs to the peptidase C1 family. (334 aa)
F4I2N3_ARATHPhosphoglycerate mutase family protein. (231 aa)
T17M13.18DUF577 domain-containing protein. (368 aa)
CYP704A1Cytochrome P450, family 704, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
F4IXJ0_ARATHTudor/PWWP/MBT superfamily protein. (645 aa)
RDL6Probable cysteine protease RDL6; Probable thiol protease. (356 aa)
T14G11.20Cysteine proteinases superfamily protein; Belongs to the peptidase C1 family. (345 aa)
CYP21-1Peptidyl-prolyl cis-trans isomerase CYP21-1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. (224 aa)
AAC1ADP,ATP carrier protein 1, mitochondrial; Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane; Belongs to the mitochondrial carrier (TC 2.A.29) family. (381 aa)
RD19ACysteine protease RD19A; Probable thiol protease (By similarity). Required for RRS1- mediated resistance against Ralstonia solanacearum. Plays a crucial role as host factor for PopP2-triggered RRS1-mediated resistance. Interacts with the R.solanacearum type III effector PopP2 to form a nuclear complex that is required for activation of the RRS1-mediated resistance response ; Belongs to the peptidase C1 family. (368 aa)
RD21ACysteine proteinase RD21A; Cysteine protease that plays a role in immunity, senescence, and biotic and abiotic stresses (Probable). Involved in immunity against the necrotrophic fungal pathogen Botrytis cinerea. Involved in elicitor-stimulated programmed cell death (PCD). During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions as PCD-promoting protease that is released from the ER body or vacuole to the cytoplasm. Accumulates in endoplasmic reticulum-derived bodies in epidermal cells and may participate in cell death in stressed or injured cells. Involved in wa [...] (462 aa)
ALPHA-VPEVacuolar-processing enzyme alpha-isozyme; Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms. Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds. (478 aa)
XBCP3Papain-like cysteine peptidase XBCP3; Belongs to the peptidase C1 family. (437 aa)
bVPEVacuolar-processing enzyme beta-isozyme; Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (By similarity). Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds. (486 aa)
GAMMA-VPEVacuolar-processing enzyme gamma-isozyme; Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms. Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds. (494 aa)
F27J15.6Similar to serine/threonine kinase 9 gb|AAD28798.1. (126 aa)
CYP59Peptidyl-prolyl cis-trans isomerase CYP59; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Influences somehow regulation of RNA pol II (CTD) phosphorylation. Binds RNA with preferences for GC-rich sequences. Probably involved in activities connecting transcription and pre-mRNA processing. Involved in brassinostroid response. (506 aa)
F28N24.20Cysteine proteinases superfamily protein; Belongs to the peptidase C1 family. (355 aa)
MLE2.7UPF0235 protein At5g63440; May play a role during early embryonic development. Probably involved in pre-mRNA splicing (By similarity); Belongs to the UPF0235 family. (232 aa)
ALEUThiol protease aleurain; May play a role in proteolysis leading to mobilization of nitrogen during senescence and starvation. (358 aa)
CYP21-2Peptidyl-prolyl cis-trans isomerase CYP21-2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (228 aa)
ER-ANT1ADP,ATP carrier protein ER-ANT1; Catalyzes the exchange of ADP and ATP across the endoplasmic reticulum membrane. (306 aa)
CYP19-4Peptidyl-prolyl cis-trans isomerase CYP19-4; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved during embryogenesis and organ development by regulating the folding of EMB30/GNOM, and thus, by modulating its activity; Belongs to the cyclophilin-type PPIase family. (201 aa)
MARD1Protein MARD1; May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway. Involved in seed dormancy control. Belongs to the FLZ family. (263 aa)
F18N11.70Thiol protease aleurain-like. (358 aa)
CATHB2Cathepsin B-like protease 2; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...] (362 aa)
CYP21-3Peptidyl-prolyl cis-trans isomerase CYP21-3, mitochondrial; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (230 aa)
CATHB3Cathepsin B-like protease 3; Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp- Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase- 1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a nu [...] (359 aa)
F19C24.6Ubiquitin-conjugating enzyme family protein. (252 aa)
PP2A4-2Uncharacterized protein PHLOEM PROTEIN 2-LIKE A4. (165 aa)
DRG2Developmentally-regulated G-protein 2; Binds GDP and GTP, and has low GTPase activity. (399 aa)
TZF5Zinc finger CCCH domain-containing protein 61. (381 aa)
PM-ANTProbable ADP,ATP carrier protein At5g56450; Catalyzes the exchange of ADP and ATP across the membrane. Belongs to the mitochondrial carrier (TC 2.A.29) family. (330 aa)
RD21BProbable cysteine protease RD21B; Probable thiol protease. (463 aa)
AMC9Metacaspase-9 subunit p10; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Required for proteolytic processing of GRI. Belongs to the peptidase C14B family. (325 aa)
dVPEVacuolar-processing enzyme delta-isozyme; Asparagine-specific endopeptidase that may be involved in processing of proteins targeted to vacuoles (By similarity). Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds. Exhibits a caspase-1-like activity in extracellular granules. At the early stage of seed development, required for the formation of the seed coat, by regulating cell death of specific cell layers in inner integument. (466 aa)
DRG1Developmentally-regulated G-protein 1; Binds GDP and GTP, and has low GTPase activity. May interact with phosphatidic acid (PA). (399 aa)
RDL2Probable cysteine protease RDL2; Probable thiol protease; Belongs to the peptidase C1 family. (362 aa)
RD21CProbable cysteine protease RD21C; Probable thiol protease; Belongs to the peptidase C1 family. (452 aa)
T32M21_20Galactose oxidase/kelch repeat superfamily protein. (514 aa)
SFC1Mitochondrial succinate-fumarate transporter 1; May transport cytoplasmic succinate, derived from fatty acid oxidation, into the mitochondrial matrix in exchange of fumarate during lipid mobilization in seed germination. Conversion of seed-reserved triacylglycerols into sucrose is necessary for growth before the onset of photosynthesis and involves fatty acid beta-oxidation, the glyoxylate cycle and gluconeogenesis. (309 aa)
SERPIN1Serpin-ZX; Inhibits metacaspase-9 (MC9) cysteine protease. Functions through cleavage of its reactive center loop and covalent binding to MC9. Involved in the control of elicitor-stimulated programmed cell death (PCD). During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions to protect cells by limiting the PCD- promoting protease RD21A activity that is released from the ER body or vacuole to the cytoplasm. Involved in the control of water stress-induced cell death by limiting the pro-death protease RD21A activity that is released from the vacuole to the cytoplasm. (391 aa)
RBG1Probable glycine-rich RNA-binding protein 1; Possibly has a role in RNA transcription or processing during stress; Belongs to the GR-RBP family. (149 aa)
F11A3.17Zinc finger CCCH domain-containing protein 21. (371 aa)
PIN1-2Peptidyl-prolyl cis-trans isomerase Pin1; Prolyl cis/trans isomerase with specificity for phospho-Ser- Pro bonds. (119 aa)
RD19CProbable cysteine protease RD19C; Probable thiol protease. (373 aa)
DRG3Developmentally-regulated G-protein 3; Binds GDP and GTP, and has low GTPase activity in vitro. (369 aa)
F10A12.10Cysteine proteinases superfamily protein; Belongs to the peptidase C1 family. (348 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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