(37 nodes) beta-Alanine metabolism, and Alcohol dehydrogenase activity, zinc-dependent network (Arabidopsis thaliana)

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	F6N18.16	Alcohol dehydrogenase-like 3. (394 aa)
	ACS	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family. (743 aa)
	F27M3.11	Amine oxidase. (677 aa)
	F27M3.9	Amine oxidase. (681 aa)
	LDL3	Lysine-specific histone demethylase 1 homolog 3; Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin. (1628 aa)
	AO1	Primary amine oxidase 1; Oxidizes preferentially the aliphatic diamine putrescine with production of the corresponding aldehyde, ammonia and hydrogen peroxide. May be involved in the regulation of developmental programmed cell death (PCD) in both vascular tissue and the root cap. Required for jasmonic acid-(MeJA) mediated early protoxylem differentiation associated with putrescine levels reduction and H(2)O(2) accumulation in roots. (650 aa)
	F27M3.13	Primary amine oxidase 2; Belongs to the copper/topaquinone oxidase family. (662 aa)
	MAF5	Protein MADS AFFECTING FLOWERING 5; Transcription factor involved in the negative regulation of flowering time in short days, probably through the photoperiodic and vernalization pathways. Prevents premature flowering, particularly in the cv. Landsberg erecta background. In non-inductive photoperiods (e.g. short days), required for flowering through VIL2-mediated maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)- dependent H3K27me3. (198 aa)
	ALDH3H1	Aldehyde dehydrogenase family 3 member H1; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Is strictely NAD(+) specific. (484 aa)
	ALDH3F1	Aldehyde dehydrogenase family 3 member F1; Belongs to the aldehyde dehydrogenase family. (484 aa)
	PAO4	Probable polyamine oxidase 4; Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and spermidine. Substrate preference is spermine > spermidine. No activity detected when putrescine or N(1)-acetylspermine are used as substrates. Plays an important role in the regulation of polyamine intracellular concentration (Probable). (497 aa)
	CuAO1	Primary amine oxidase; Belongs to the copper/topaquinone oxidase family. (712 aa)
	T4C9.130	Amine oxidase. (741 aa)
	MHK10.21	Amine oxidase. (776 aa)
	T4C12_30	Alcohol dehydrogenase-like 6. (381 aa)
	ALDH2B7	Aldehyde dehydrogenase family 2 member B7, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family. (534 aa)
	LDL1	Lysine-specific histone demethylase 1 homolog 1; Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin of the floral repressor FLOWERING LOCUS C (FLC) and the sporophytically silenced floral repressor FWA. Seems to act in partial redundancy with FLOWERING LOCUS D (FLD) to repress FLC expression. Required for cytosine methylation of FWA. Controls primary seed dormancy by regulating DOG1 and abscisic acid signaling-related genes. In association with OTU6/OTLD1, involved in transcriptional gene repression via histone deubiquitination and demet [...] (844 aa)
	F13O11.3	Alcohol dehydrogenase-like 4; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
	AAE7	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family. (569 aa)
	ALDH3I1	Aldehyde dehydrogenase family 3 member I1, chloroplastic; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent. (550 aa)
	PDC2	Pyruvate decarboxylase 2; Belongs to the TPP enzyme family. (607 aa)
	K5J14.5	Alcohol dehydrogenase-like 7. (390 aa)
	TAT7	Probable aminotransferase TAT2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (414 aa)
	PAO1	Polyamine oxidase 1; Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives. Substrate preference is thermospermine > norspermine > spermine > N(1)-acetylspermine. No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates. Plays an important role in the regulation of polyamine intracellular concentration (Probable). Involved in the production of hydrogen peroxide in response to salt and cold stresses. (472 aa)
	PAO3	Polyamine oxidase 3; Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine, spermidine and their acetyl derivatives. Substrate preference is spermidine > spermine > N(1)-acetylspermidine > N(1)-acetylspermine. Plays an important role in the regulation of polyamine intracellular concentration (Probable). Involved in the production of hydrogen peroxide during pollen tube growth. Hydrogen peroxide triggers the opening of the hyperpolarization-activated calcium permeable channels in pollen, and thus regulates [...] (488 aa)
	F12E4.110	Acylphosphatase. (171 aa)
	PDC3	Pyruvate decarboxylase 3; Belongs to the TPP enzyme family. (592 aa)
	PDC4	Pyruvate decarboxylase 4; Belongs to the TPP enzyme family. (603 aa)
	TYRDC	Probable tyrosine decarboxylase 2; Belongs to the group II decarboxylase family. (545 aa)
	F23N14_50	Amine oxidase. (687 aa)
	PAO2	Polyamine oxidase 2; Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine, spermidine and their acetyl derivatives. Substrate preference is N(1)-acetylspermine > spermine > spermidine. Plays an important role in the regulation of polyamine intracellular concentration (Probable). Involved in abscisic acid-mediated developmental processes. May contribute to nitric oxide-mediated effects on root growth. (490 aa)
	T4C9.120	Amine oxidase. (300 aa)
	T4C9.110	Amine oxidase; Belongs to the copper/topaquinone oxidase family. (460 aa)
	ALDH2B4	Aldehyde dehydrogenase family 2 member B4, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family. (538 aa)
	PAO5	Probable polyamine oxidase 5; Flavoenzyme involved in polyamine back-conversion. Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives. Substrate preference is spermine > N(1)-acetylspermine > thermospermine > norspermine. Plays an important role in the regulation of polyamine intracellular concentration. Involved in xylem differentiation by controlling thermospermine homeostasis, and participating in the tightly controlled interplay between auxin and cytokinin that is necessary for proper xylem differentiation. Involved in the [...] (533 aa)
	ALDH7B4	Aldehyde dehydrogenase family 7 member B4. (508 aa)
	T22F8.220	Microtubule-associated protein-like protein. (166 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAE7	ACS	Q8VZF1	B9DGD6	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	0.952
AAE7	ALDH2B4	Q8VZF1	Q9SU63	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 2 member B4, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family.	0.947
AAE7	ALDH2B7	Q8VZF1	Q8S528	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 2 member B7, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family.	0.922
AAE7	ALDH3F1	Q8VZF1	Q70E96	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 3 member F1; Belongs to the aldehyde dehydrogenase family.	0.922
AAE7	ALDH3H1	Q8VZF1	Q70DU8	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 3 member H1; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Is strictely NAD(+) specific.	0.949
AAE7	ALDH3I1	Q8VZF1	Q8W033	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 3 member I1, chloroplastic; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent.	0.922
AAE7	ALDH7B4	Q8VZF1	Q9SYG7	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 7 member B4.	0.922
AAE7	F12E4.110	Q8VZF1	Q9LZF2	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	Acylphosphatase.	0.902
ACS	AAE7	B9DGD6	Q8VZF1	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Acetate/butyrate--CoA ligase AAE7, peroxisomal; Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate. Belongs to the ATP-dependent AMP-binding enzyme family.	0.952
ACS	ALDH2B4	B9DGD6	Q9SU63	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 2 member B4, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family.	0.965
ACS	ALDH2B7	B9DGD6	Q8S528	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 2 member B7, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family.	0.959
ACS	ALDH3F1	B9DGD6	Q70E96	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 3 member F1; Belongs to the aldehyde dehydrogenase family.	0.963
ACS	ALDH3H1	B9DGD6	Q70DU8	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 3 member H1; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Is strictely NAD(+) specific.	0.968
ACS	ALDH3I1	B9DGD6	Q8W033	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 3 member I1, chloroplastic; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent.	0.961
ACS	ALDH7B4	B9DGD6	Q9SYG7	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Aldehyde dehydrogenase family 7 member B4.	0.955
ACS	F12E4.110	B9DGD6	Q9LZF2	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Acylphosphatase.	0.900
ACS	PDC2	B9DGD6	Q9FFT4	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Pyruvate decarboxylase 2; Belongs to the TPP enzyme family.	0.403
ACS	PDC3	B9DGD6	Q9M039	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Pyruvate decarboxylase 3; Belongs to the TPP enzyme family.	0.412
ACS	PDC4	B9DGD6	Q9M040	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Pyruvate decarboxylase 4; Belongs to the TPP enzyme family.	0.412
ACS	T22F8.220	B9DGD6	Q9T038	Acetyl-coenzyme A synthetase, chloroplastic/glyoxysomal; Catalyzes the production of acetyl-CoA, an activated form of acetate that can be used for lipid synthesis or for energy generation. May play a limited role in the biosynthesis of lipids. Belongs to the ATP-dependent AMP-binding enzyme family.	Microtubule-associated protein-like protein.	0.461