(6 nodes) Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione, and Deglycase PfpI network (Arabidopsis thaliana)

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Your Input:
	GLX2-2	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (258 aa)
	GLX1	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (283 aa)
	T6D22.20	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
	DJ1F	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family. (399 aa)
	GLX2-5	Hydroxyacylglutathione hydrolase 2, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (324 aa)
	DJ1E	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family. (398 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DJ1E	DJ1F	Q9ZV19	Q9M1G8	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.903
DJ1E	GLX1	Q9ZV19	O65398	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.967
DJ1E	GLX2-2	Q9ZV19	O24496	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	0.980
DJ1E	GLX2-5	Q9ZV19	Q9SID3	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Hydroxyacylglutathione hydrolase 2, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.	0.981
DJ1E	T6D22.20	Q9ZV19	Q8H0V3	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.973
DJ1F	DJ1E	Q9M1G8	Q9ZV19	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.903
DJ1F	GLX1	Q9M1G8	O65398	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.970
DJ1F	GLX2-2	Q9M1G8	O24496	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	0.980
DJ1F	GLX2-5	Q9M1G8	Q9SID3	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Hydroxyacylglutathione hydrolase 2, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.	0.981
DJ1F	T6D22.20	Q9M1G8	Q8H0V3	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.966
GLX1	DJ1E	O65398	Q9ZV19	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.967
GLX1	DJ1F	O65398	Q9M1G8	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.970
GLX1	GLX2-2	O65398	O24496	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	0.998
GLX1	GLX2-5	O65398	Q9SID3	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	Hydroxyacylglutathione hydrolase 2, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.	0.998
GLX1	T6D22.20	O65398	Q8H0V3	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.929
GLX2-2	DJ1E	O24496	Q9ZV19	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.980
GLX2-2	DJ1F	O24496	Q9M1G8	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	DJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.980
GLX2-2	GLX1	O24496	O65398	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.998
GLX2-2	T6D22.20	O24496	Q8H0V3	Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.997
GLX2-5	DJ1E	Q9SID3	Q9ZV19	Hydroxyacylglutathione hydrolase 2, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.	DJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family.	0.981