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CBP20 CBP20 OTP51 OTP51 CLPS3 CLPS3 ABH1 ABH1 SEN1 SEN1 MQM1.13 MQM1.13 SEN2 SEN2 CLPS5 CLPS5 MTERF15 MTERF15 Q6DBN3_ARATH Q6DBN3_ARATH Q2V3Q6_ARATH Q2V3Q6_ARATH RNL RNL F13C5.100 F13C5.100 MYH19.80 MYH19.80 F11A12.6 F11A12.6 emb1067 emb1067
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CBP20Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA- mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG- capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N- terminal loop and lock the CBC into a high affinity cap-binding state wi [...] (257 aa)
OTP51Pentatricopeptide repeat-containing protein At2g15820, chloroplastic; Promotes the splicing of group II introns in chloroplasts. Required for the splicing of intron 2 of plastid ycf3 transcripts, a factor required for the assembly of photosystem I (PSI). Involved in the splicing of several other group-IIa introns. May be involved in the splicing of precursor forms of trnL, trnG, trnI, and trnA. Required for the assembly of PSI and PSII. (849 aa)
CLPS3Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation (By similarity). Functions in gametophyte, embryo and postembryotic development. Belongs to the Clp1 family. Clp1 subfamily. (444 aa)
ABH1Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state [...] (848 aa)
SEN1tRNA-splicing endonuclease subunit Sen2-1; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structur [...] (237 aa)
MQM1.13RNA 2'-phosphotransferase, Tpt1 / KptA family. (212 aa)
SEN2tRNA-splicing endonuclease subunit Sen2-2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structur [...] (250 aa)
CLPS5Protein CLP1 homolog 5; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation. (424 aa)
MTERF15Transcription termination factor MTERF15, mitochondrial; Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity. Essential for normal plant growth and development. Binds to RNA but not to double-stranded DNA. (445 aa)
Q6DBN3_ARATHtRNA-splicing endonuclease subunit. (254 aa)
Q2V3Q6_ARATHtRNA-intron endonuclease. (118 aa)
RNLtRNA ligase 1; Essential component of stress-response pathways entailing repair of RNA breaks with 2',3'-cyclic phosphate and 5'-OH ends. Tri-functional enzyme that repairs RNA breaks with 2',3'-cyclic-PO(4) and 5'-OH ends. The ligation activity requires three sequential enzymatic activities: opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester (CPDase activity), phosphorylation of the 5' terminus of the 3' half- tRNA in the presence of ATP (kinase activity) and ligation of the two tRNA halves in an ATP-dependent reaction (ligase activity). D [...] (1104 aa)
F13C5.100Cyclic phosphodiesterase; Hydrolyzes ADP-ribose 1'',2''-cyclic phosphate (Appr>1) that is produced during tRNA splicing into ADP-ribose 1''-phosphate (Appr- 1''p). Acts also on nucleoside 2',3'-cyclic phosphates. (181 aa)
MYH19.80Pre-mRNA cleavage complex II protein. (107 aa)
F11A12.6tRNA-splicing endonuclease subunit. (205 aa)
emb1067RNA 2'-phosphotransferase, Tpt1 / KptA family. (289 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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