STRINGSTRING
BHLH104 BHLH104 STKL1 STKL1 BZIP1 BZIP1 BZIP9 BZIP9 HXK3 HXK3 HKL1 HKL1 STP10 STP10 BHLH34 BHLH34 NAC60 NAC60 SBE2.2 SBE2.2 HKL3 HKL3 A0A1P8ARU2 A0A1P8ARU2 SBE2.1 SBE2.1 STKL2 STKL2 RPT5B RPT5B HXK2 HXK2 BZIP63 BZIP63 VHA-B1 VHA-B1 HXK1 HXK1 ATHXK4 ATHXK4 GATA21 GATA21 RHIP1 RHIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BHLH104Transcription factor bHLH104. (283 aa)
STKL1Transcription factor STKL1; Transcription repressor that binds DNA in a sequence-specific manner, 5'-GCCT-3', to regulate the expression of PGR. Acts as a modulatory component for the glucose-triggered developmental leaf growth process. (345 aa)
BZIP1Basic leucine zipper 1; Transcription factor that binds to the C-box-like motif (5'- TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters involved in sugar signaling. Activated by low energy stress both at transcriptional and post-transcriptional mechanisms. Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark- induced starvation response. Transcription activator of the mannan synthase CSLA9. Recognizes and binds to DNA-specific sequence of CSLA9 promoter. Belongs to the bZIP [...] (145 aa)
BZIP9Basic leucine zipper 9; Transcription factor; Belongs to the bZIP family. (277 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
HKL1Hexokinase-3; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (498 aa)
STP10Sugar transport protein 10; Mediates an active uptake of hexoses, probably by sugar/hydrogen symport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (514 aa)
BHLH34Transcription factor bHLH34. (320 aa)
NAC60NAC domain-containing protein 60; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). Transcription factor involved in modulation of abscisic acid (ABA) signaling. Attenuates ABA sensitivity and glucose-induced ABA accumulation. Reduces the expression of ABI4 gene. (335 aa)
SBE2.21,4-alpha-glucan-branching enzyme 2-2, chloroplastic/amyloplastic; Catalyzes the formation of the alpha-1,6-glucosidic linkages in starch by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (805 aa)
HKL3Probable hexokinase-like 2 protein; Fructose and glucose phosphorylating enzyme. (493 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
SBE2.11,4-alpha-glucan-branching enzyme 2-1, chloroplastic/amyloplastic; Catalyzes the formation of the alpha-1,6-glucosidic linkages in starch by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (858 aa)
STKL2Transcription factor STKL2; Transcription repressor that binds DNA in a sequence-specific manner, 5'-GCCT-3', to regulate the expression of PGR. Acts as a modulatory component for the glucose-triggered developmental leaf growth process. (319 aa)
RPT5B26S proteasome regulatory subunit 6A homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (423 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
BZIP63Basic leucine zipper 63; Transcription factor involved in controlling responses to starvation. BZIP2-BZIP63-KIN10 complex binds to the ETFQO promoter to up-regulate its transcription. (314 aa)
VHA-B1V-type proton ATPase subunit B1; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (486 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
ATHXK4Hexokinase-4; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (502 aa)
GATA21GATA transcription factor 21; Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. Involved in the modulation of chloroplast development, growth and division in a cytokinin-dependent manner. Repressor of the gibberellic acid (GA) signaling pathway that represses flowering and modulates greening, in a SOC1-dependent manner. Prevents the accumulation of SOC1 during flowering. Promotes chlorophyll biosynthesis throughout the plant, by regulating chlorophyll biosynthetic genes (e.g. HEMA1 and GUN4) and chloroplast localized glutamate synth [...] (398 aa)
RHIP1RGS1-HXK1-interacting protein 1; Required for some glucose-regulated gene expression, being a physical connection between RGS1 and HXK1 in sugar signaling. Prevents roots and inflorecences growth. (263 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (20%) [HD]