STRINGSTRING
FH9 FH9 Q8GXC9_ARATH Q8GXC9_ARATH ADF12 ADF12 ARPC2A ARPC2A NET2C NET2C VHA-B3 VHA-B3 VCL1 VCL1 FH5 FH5 WLIM1 WLIM1 T15M6.8 T15M6.8 FH14 FH14 FH12 FH12 F15H21.4 F15H21.4 ANN5 ANN5 PRF3 PRF3 FH19 FH19 FH16 FH16 KIN14E KIN14E FIM3 FIM3 FH6 FH6 FIM5 FIM5 VIII-1 VIII-1 XI-2 XI-2 SCAR3 SCAR3 ADF10 ADF10 ARP2-2 ARP2-2 NET1A NET1A AIP1-2 AIP1-2 VLN5 VLN5 ADF11 ADF11 WLIM2B WLIM2B ARPC5A ARPC5A XI-J XI-J CPB CPB FH11 FH11 ARP3 ARP3 FH1 FH1 AIP1-1 AIP1-1 ADF3 ADF3 ADF4 ADF4 ADF6 ADF6 NET1C NET1C ADF5 ADF5 FH7 FH7 PI4KA1 PI4KA1 F11A17.4 F11A17.4 FH10 FH10 ARPC1B ARPC1B FIM4 FIM4 A0A1I9LNY7 A0A1I9LNY7 ARPC5B ARPC5B XI-E XI-E XI-C XI-C NET1D NET1D NET2B NET2B XI-B XI-B VIII-A VIII-A XI-A XI-A F8D11.8 F8D11.8 SCAB2 SCAB2 NET2D NET2D XI-F XI-F XI-G XI-G XI-D XI-D ARPC2B ARPC2B F4J6D3_ARATH F4J6D3_ARATH NET1B NET1B VIII-B VIII-B XI-H XI-H ARPC4 ARPC4 CIP1 CIP1 VIII-2 VIII-2 GEX2 GEX2 XI-K XI-K NET4A NET4A WLIN2A WLIN2A FH8 FH8 FH2 FH2 FH3 FH3 FH4 FH4 SCAB1 SCAB1 ADF9 ADF9 FIM2 FIM2 VLN4 VLN4 CAP1 CAP1 PLIM2A PLIM2A ARPC1A ARPC1A VLN1 VLN1 VLN2 VLN2 VLN3 VLN3 NET3C NET3C CPA-2 CPA-2 NET2A NET2A VHA-B1 VHA-B1 ERD10 ERD10 XI-I XI-I PLIM2B PLIM2B ARPC3 ARPC3 T5K18.180 T5K18.180 PRF4 PRF4 PRF5 PRF5 XI-1 XI-1 ADF1 ADF1 ADF2 ADF2 PRF2 PRF2 PRF1 PRF1 NET3B NET3B PLIM2C PLIM2C PIP5K1 PIP5K1 ADF8 ADF8 SCAR4 SCAR4 SCAR2 SCAR2 SINE1 SINE1 NET3A NET3A ADF7 ADF7 SCAR1 SCAR1 FIM1 FIM1 NET4B NET4B SCAB3 SCAB3
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proteins of unknown 3D structure
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FH9Formin-like protein 9; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (782 aa)
Q8GXC9_ARATHActin cross-linking protein, putative (DUF569). (335 aa)
ADF12Actin-depolymerizing factor 12; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (137 aa)
ARPC2AActin-related protein 2/3 complex subunit 2A; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the ARPC2 family. (318 aa)
NET2CProtein NETWORKED 2C; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (848 aa)
VHA-B3V-type proton ATPase subunit B3; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (487 aa)
VCL1Protein VACUOLELESS1; Required for vacuole biogenesis and vacuole enlargment in dividing and expanding cells. Involved in the docking or fusion of prevacuolar vesicles. Important for the function of both male and female gametophytes, but is not essential for the germination and development of pollen. (858 aa)
FH5Formin-like protein 5; Might be involved in the organization and polarity of the actin cytoskeleton. Interacts with the barbed end of actin filaments and nucleates actin-filament polymerization in vitro. Seems to play a role in cytokinesis. (900 aa)
WLIM1LIM domain-containing protein WLIM1; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]. (190 aa)
T15M6.8WEB family protein. (284 aa)
FH14Formin-like protein 14; Belongs to the formin-like family. Class-II subfamily. (1230 aa)
FH12Formin-like protein 12; Belongs to the formin-like family. Class-II subfamily. (299 aa)
F15H21.4Myosin heavy chain-like protein. (555 aa)
ANN5Annexin D5. (316 aa)
PRF3Profilin-3; Binds to actin monomers and regulates the organization of the actin cytoskeleton. Can increase the critical concentration (Cc) of actin assembly in vitro. Acts as downstream effector of the hydrogen sulfide signaling to regulate the assembly and depolymerization of F-actin. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (Probable). Binding to the poly-proline motif of formin induces oligomerization of PRF3. PRF3 oligomers inhibit formin-mediated actin assembly to modulate plant immunity triggered by pathog [...] (168 aa)
FH19Formin-like protein 19; Belongs to the formin-like family. Class-II subfamily. (464 aa)
FH16Formin-like protein 16. (722 aa)
KIN14EKinesin-like protein KIN-14E; Minus-end microtubule-dependent motor protein involved in the regulation of cell division and trichome morphogenesis through microtubules bundling. Possesses basal and microtubule-stimulated ATPase activities. Acts as a hub that brings together microtubules and actin filaments to modulate the cytoskeleton during trichome formation and morphogenesis. Could be involved in the negative regulation of root growth. (1260 aa)
FIM3Fimbrin-3; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (714 aa)
FH6Formin-like protein 6; Might be involved in the organization and polarity of the actin cytoskeleton. (899 aa)
FIM5Fimbrin-5; Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin bundles. Stabilizes and prevents F-actin depolymerization mediated by latrunculin B (LatB). (687 aa)
VIII-1Myosin-1; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). Involved in endocytosis via its action in endosomal trafficking. (1166 aa)
XI-2Myosin-6; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Targets the peroxisome through an interaction with RABC2A. Required for deve [...] (1505 aa)
SCAR3Protein SCAR3; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (1020 aa)
ADF10Actin-depolymerizing factor 10; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (140 aa)
ARP2-2Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, [...] (389 aa)
NET1AProtein NETWORKED 1A; Plant-specific actin binding protein. Associates with F-actin at the plasma membrane and plasmodesmata. May be part of a membrane- cytoskeletal adapter complex; Belongs to the NET family. (1728 aa)
AIP1-2Actin-interacting protein 1-2; Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins. (609 aa)
VLN5Villin-5; Major actin filament stabilizing factor and regulator of actin dynamics. Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Required for the construction of actin collars in pollen tubes. Acts synergistically with VLN2 (AC O81644) to regulate polarized pollen tube growth. Belongs to the villin/gelsolin family. (962 aa)
ADF11Putative actin-depolymerizing factor 11; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (133 aa)
WLIM2BLIM domain-containing protein WLIM2b; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]. (199 aa)
ARPC5AActin-related protein 2/3 complex subunit 5A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (132 aa)
XI-JMyosin-16; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1242 aa)
CPBProbable F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (256 aa)
FH11Formin-like protein 11; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (884 aa)
ARP3Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, [...] (427 aa)
FH1Formin-like protein 1; Might be involved in the organization and polarity of the actin cytoskeleton. Involved in polar pollen cell growth process by maintaining tip-focused cell membrane expansion for the polar extension of pollen tubes; Belongs to the formin-like family. Class-I subfamily. (1051 aa)
AIP1-1Actin-interacting protein 1-1; Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins. (611 aa)
ADF3Actin-depolymerizing factor 3; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (139 aa)
ADF4Actin-depolymerizing factor 4; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Contributes to the stochastic dynamic turnover of actin filaments. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Involved in resistance triggered by the effector AvrPphB of Pseudomonas syringae pv tomato (Pst). May modulate the AvrPphB-RPS5-mediated defense signal transduction pathway. During AvrPphB-triggered resistance signaling pathway, involved in the control of MPK3 an [...] (139 aa)
ADF6Actin-depolymerizing factor 6; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (146 aa)
NET1CProtein NETWORKED 1C; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (1111 aa)
ADF5Actin-depolymerizing factor 5; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (143 aa)
FH7Formin-like protein 7; Might be involved in the organization and polarity of the actin cytoskeleton. (929 aa)
PI4KA1Phosphatidylinositol 4-kinase alpha 1; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate. Can bind to phosphatidylinositol 4-monophosphate (PI-4-P or PtdIns4P), phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2 or PtdIns4,5P2), and phosphatidic acid (PtdOH), but not to 3- phosphoinositides. May function upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway. (2028 aa)
F11A17.4Kinase-interacting family protein; May be involved in the receptor-like kinase-mediated signal transduction pathway. (297 aa)
FH10Formin-like protein 10; Might be involved in the organization and polarity of the actin cytoskeleton. (841 aa)
ARPC1BActin-related protein 2/3 complex subunit 1B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the WD repeat ARPC1 family. (378 aa)
FIM4Fimbrin-4; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (652 aa)
A0A1I9LNY7Formin-like protein. (160 aa)
ARPC5BActin-related protein 2/3 complex subunit 5B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (135 aa)
XI-EMyosin-11; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks, mitochondria and peroxisomes. (1529 aa)
XI-CMyosin-9; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1538 aa)
NET1DProtein NETWORKED 1D; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (1733 aa)
NET2BProtein NETWORKED 2B; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (928 aa)
XI-BMyosin-8; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1500 aa)
VIII-AMyosin-3; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1153 aa)
XI-AMyosin-7; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1730 aa)
F8D11.8P-loop containing nucleoside triphosphate hydrolases superfamily protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (170 aa)
SCAB2Stomatal closure-related actin-binding protein 2; Probable plant-specific actin binding protein that bundles and stabilizes microfilaments (MFs). (492 aa)
NET2DProtein NETWORKED 2D; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (947 aa)
XI-FMyosin-12; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1556 aa)
XI-GMyosin-13; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1493 aa)
XI-DMyosin-10; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1770 aa)
ARPC2BActin-related protein 2/3 complex subunit 2B; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development (By similarity). (374 aa)
F4J6D3_ARATHKinase interacting (KIP1-like) family protein. (357 aa)
NET1BProtein NETWORKED 1B; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (1710 aa)
VIII-BMyosin-4; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1134 aa)
XI-HMyosin-14; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1516 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (169 aa)
CIP1COP1-interactive protein 1; Positive regulator of abscisic acid (ABA)-mediated signaling pathways involved in abiotic stress responses (e.g. osmotic stress) and leading to various plant adaptation (e.g. stomata closure). (1586 aa)
VIII-2Myosin-2; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). Involved in endocytosis via its action in endosomal trafficking; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class VIII subfamily. (1220 aa)
GEX2Protein GAMETE EXPRESSED 2. (914 aa)
XI-KMyosin-17; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells and in the elongation of trichome stalk and branches. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Acts as the primary co [...] (1531 aa)
NET4AProtein NETWORKED 4A; Plant-specific actin binding protein. Associates with F-actin at the tonoplast. May be part of a membrane-cytoskeletal adapter complex. (558 aa)
WLIN2ALIM domain-containing protein WLIM2a; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]. (200 aa)
FH8Formin-like protein 8; Might be involved in the organization and polarity of the actin cytoskeleton. Interacts with the barbed end of actin filaments and nucleates actin-filament polymerization in vitro. (760 aa)
FH2Formin-like protein 2; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (894 aa)
FH3Formin-like protein 3; Acts as actin nucleation factor that directs the formation of actin cables and polarized growth in pollen tubes. (785 aa)
FH4Formin-like protein 4; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (763 aa)
SCAB1Stomatal closure-related actin-binding protein 1; Plant-specific actin binding protein that bundles and stabilizes microfilaments (MFs). Has no nucleation or capping activity. Regulates MF reorganization during stomatal closure. The binding to F- actin is insensitive to Ca(2+) and pH. Binds weakly to inositol phosphates ; Belongs to the SCAB family. (496 aa)
ADF9Actin-depolymerizing factor 9; Does not display typical F-actin depolymerizing activity. Exhibits a high ability to stabilize and cross-link actin filaments. Functions as an actin bundling protein with the highest efficiency under acidic conditions. May play a role in the modulation of levels of histone H3 lysine 4 trimethylation and H3 lysine 9 and 14 acetylation at the FLC locus. Belongs to the actin-binding proteins ADF family. (141 aa)
FIM2Fimbrin-2; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (654 aa)
VLN4Villin-4; Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Involved in root hair growth through regulating actin organization in a Ca(2+)-dependent manner. (974 aa)
CAP1Cyclase-associated protein 1; Actin monomer binding protein that accelerates the exchange of ADP for ATP. Regulates the pool of unpolymerized ATP-actin. Key intermediate between actin-depolymerizing factor (ADF)-mediated disassembly and the profilin-based nucleation and elongation machinery. Belongs to the CAP family. (476 aa)
PLIM2ALIM domain-containing protein PLIM2a; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are inhibited by pH > 6.8 but are [Ca(2+)] independent. (226 aa)
ARPC1AActin-related protein 2/3 complex subunit 1A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (378 aa)
VLN1Villin-1; Binds actin and actin filament bundles in a Ca(2+)/calmodulin-insensitive manner, but is unable to sever, cap, and nucleate actin filament formation in vitro. Does not protect individual filaments from severing by VLN3 (AC O81645). Belongs to the villin/gelsolin family. (909 aa)
VLN2Villin-2; Ca(2+)-regulated actin-binding protein. Involved in actin filaments bundling. Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Required for the construction of actin collars in pollen tubes. Acts redundantly with VLN5 (AC Q9LVC6) to generate thick actin filament bundles and to regulate polarized pollen tube growth. Acts redundantly with VLN3 (AC O81645) to regulate directional organ growth and in sclerenchyma development (respectively). Belongs to the villin/gelsolin family. (976 aa)
VLN3Villin-3; Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but severs actin filaments in a calcium-dependent manner, regardless of the presence or not of VLN1 (AC O81643). Acts redundantly with VLN2 (AC O81644) to generate thick actin filament bundles, to regulate directional organ growth and in sclerenchyma development. (965 aa)
NET3CProtein NETWORKED 3C; Plant-specific actin binding protein. Part of a membrane- cytoskeletal adapter complex that forms a bridge between the endoplasmic reticulum and the plasma membrane. Belongs to the NET family. (225 aa)
CPA-2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (308 aa)
NET2AProtein NETWORKED 2A; Plant-specific actin binding protein. Associates with F-actin at the plasma membrane in growing pollen tubes. May be part of a membrane-cytoskeletal adapter complex; Belongs to the NET family. (947 aa)
VHA-B1V-type proton ATPase subunit B1; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (486 aa)
ERD10Dehydrin ERD10. (260 aa)
XI-IMyosin-15; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria. Plays a role in nuclear shape determination. Drives nuclear movement along actin filaments. As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasm [...] (1522 aa)
PLIM2BLIM domain-containing protein PLIM2b; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are inhibited by pH > 6.8 but are [Ca(2+)] independent. (205 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (174 aa)
T5K18.180Profilin family protein; Belongs to the profilin family. (148 aa)
PRF4Profilin-4; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Acts redundantly with PRF5 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth. Functions probably by favoring formin-mediated actin polymerization at pollen tube tips. (134 aa)
PRF5Profilin-5; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Acts redundantly with PRF4 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth. Functions probably by favoring formin-mediated actin polymerization at pollen tube tips. (134 aa)
XI-1Myosin-5; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Contributes to the trafficking of Golgi stacks, mitochondria and peroxisomes. Required for development of pavement cells, trichomes, and stigmatic papillae. (1520 aa)
ADF1Actin-depolymerizing factor 1; Actin-depolymerizing protein. Stimulates F-actin depolymerization. Involved in plant development, cell organ expansion and flowering by controlling breakdown of thick actin cables. Severs actin filaments or bundles and promotes actin cytoskeleton disassembly. Binds monomeric actin (G- actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. (139 aa)
ADF2Actin-depolymerizing factor 2; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Required for normal cell growth, plant development, cell organ expansion and flowering. Essential for root-knot nematode infection. (137 aa)
PRF2Profilin-2; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds G- actin and poly-L-proline with low affinity in vitro. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. May be involved in the cross-talk between vesicular trafficking and the actin cytoskeleton. At high concentrations, profilin prevents the pol [...] (131 aa)
PRF1Profilin-1; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. Coordinates the stochastic dynamic properties of actin filaments by modulating formin- mediated actin nucleation and assembly during axial cell expansion. Binds G-actin and poly-L-proline in vitro. Inhib [...] (131 aa)
NET3BProtein NETWORKED 3B; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex; Belongs to the NET family. (215 aa)
PLIM2CLIM domain-containing protein PLIM2c; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. Associates predominantly with long and dynamic actin bundles in the shank of growing pollen tubes. The actin regulatory activities are inhibited by pH > 6.8 and/or high [Ca(2+)]. (213 aa)
PIP5K1Phosphatidylinositol 4-phosphate 5-kinase 1; Catalyzes the synthesis of phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4-bisphosphate. (752 aa)
ADF8Actin-depolymerizing factor 8; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (140 aa)
SCAR4Protein SCAR4; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (1170 aa)
SCAR2Protein SCAR2; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. Belongs to the SCAR/WAVE family. (1399 aa)
SINE1Protein SINE1; Plays a role in nucleus positioning in guard cells. (560 aa)
NET3AProtein NETWORKED 3A; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (269 aa)
ADF7Actin-depolymerizing factor 7; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Required for pollen tube growth. Promotes turnover of longitudinal actin cables by severing actin filaments in pollen tubes. (137 aa)
SCAR1Protein SCAR1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (821 aa)
FIM1Fimbrin-1; Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin aggregates. Stabilizes and prevents F-actin depolymerization mediated by profilin. Key regulator of actin cytoarchitecture, probably involved in cell cycle, cell division, cell elongation and cytoplasmic tractus. (687 aa)
NET4BProtein NETWORKED 4B; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (517 aa)
SCAB3Stomatal closure-related actin-binding protein 3; Probable plant-specific actin binding protein that bundles and stabilizes microfilaments (MFs). (490 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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