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| | F4K355_ARATH | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (258 aa) |
| | MORC5 | Protein MICRORCHIDIA 5; Exhibits ATPase activity. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair. Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing. (708 aa) |
| | MAF19.18 | Putative endonuclease or glycosyl hydrolase. (374 aa) |
| | F4K1A0_ARATH | Reverse transcriptase-like protein. (142 aa) |
| | MJE4.10 | Putative endonuclease or glycosyl hydrolase. (192 aa) |
| | MXC9.18 | Las1-like family protein. (611 aa) |
| | MJP23.7 | DNA mismatch repair protein MutS, type 2. (796 aa) |
| | MORC7 | Protein MICRORCHIDIA 7; Exhibits ATPase activity. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair. Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing. Together with MORC4, acts to suppress a wide set of non- methylated protein-coding genes, especially involved in pathogen response. Positive regulators of defense against the oomycete Hyaloperonospora arabidopsidis (Hpa). (707 aa) |
| | MORC3 | Protein MICRORCHIDIA 3; Exhibits ATPase activity. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair. Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing. (589 aa) |
| | APE2 | DNA-(apurinic or apyrimidinic site) lyase 2; Exhibits apurinic/apyrimidinic (AP) endonuclease activity in vitro. By contrast, another report show that APE2 has no biochemical activity. Unable to catalyze the conversion of 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) to 3'-OH. Has no in vitro 3'- phosphatase activity. Redundant with APE1L and at least one functional allele is required for seed viability. Has a strong non-specific affinity to DNA. (610 aa) |
| | F4JN57_ARATH | DDE family endonuclease. (527 aa) |
| | F7A19.31 | Ribonuclease T2 family protein; Belongs to the RNase T2 family. (247 aa) |
| | F4HSA3_ARATH | Putative endonuclease or glycosyl hydrolase. (228 aa) |
| | F17L21.2 | Paired amphipathic helix repeat-containing protein. (184 aa) |
| | F8L10.14 | Thioredoxin family protein. (313 aa) |
| | F4HNV0_ARATH | Endonuclease/glycosyl hydrolase. (143 aa) |
| | F4JKS9_ARATH | Non-LTR retroelement reverse transcriptase. (141 aa) |
| | PRORP3 | Proteinaceous RNase P 3; Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA); Belongs to the PPR family. P subfamily. (576 aa) |
| | ENDO5 | Endonuclease 5; Hydrolyzes, with low efficiency, only single-stranded DNA and RNA without apparent specificity for bases. Endonuclease that recognizes and cleaves some mismatches with high efficiency, including heteroduplex double-stranded DNA; mostly efficient on T/G, A/G and G/G mismatches, less efficient for T/T and poorly efficient for C/C, A/A, T/C and A/C. (296 aa) |
| | ENDO4 | Endonuclease 4; Endonuclease that can use single-stranded RNA and DNA as substrates. In contradiction with cannot hydrolyze single-stranded DNA and does not cleave mismatches. (299 aa) |
| | A_IG005I10.3 | Double-stranded RNA-binding domain (DsRBD)-containing protein. (190 aa) |
| | T13O15.5 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (294 aa) |
| | F4JD25_ARATH | Putative endonuclease or glycosyl hydrolase. (254 aa) |
| | F4JD16_ARATH | C2 calcium/lipid-binding endonuclease/exonuclease/phosphatase. (627 aa) |
| | F4JC91_ARATH | Putative endonuclease or glycosyl hydrolase. (383 aa) |
| | F4JA77_ARATH | Non-LTR retroelement reverse transcriptase. (214 aa) |
| | F11A12.6 | tRNA-splicing endonuclease subunit. (205 aa) |
| | F4J5L3_ARATH | RBR-type E3 ubiquitin transferase. (382 aa) |
| | TRZ4 | tRNAse Z TRZ4, mitochondrial; Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'- trailer from precursor tRNA. Can process the mitochondrial tRNA-like structures (t-elements). (942 aa) |
| | EME1B | Crossover junction endonuclease EME1B; Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meiot [...] (551 aa) |
| | CPSF30 | 30-kDa cleavage and polyadenylation specificity factor 30; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Mediates poly(A) site selection. Binds RNA in a calcium- dependent manner. Exhibits endonuclease activity with an ability to nick and degrade linear as well as circular single-stranded RNA that leaves RNA 3' ends with hydroxyl groups, thus mediating processing of the pre-mRNA as a pre [...] (631 aa) |
| | A6QR85_ARATH | Putative endonuclease or glycosyl hydrolase. (157 aa) |
| | A0A1P8BG68 | Ribonuclease H superfamily polynucleotidyl transferase. (127 aa) |
| | CAN1 | Staphylococcal-like nuclease CAN1; Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. Possesses activity toward the single-stranded DNA, double-stranded DNA and RNA. May be involved in genomic DNA degradation during programmed cell death. (323 aa) |
| | MAF19.19 | Putative endonuclease or glycosyl hydrolase with C2H2-type zinc finger domain-containing protein. (1057 aa) |
| | A0A1I9LN10 | Reverse transcriptase-like protein. (279 aa) |
| | RTL1 | RNAse II-like 1. (289 aa) |
| | A0A1P8AY32 | Reverse transcriptase-like protein. (81 aa) |
| | JHS1 | DNA replication ATP-dependent helicase/nuclease JHS1; Essential protein required during embryogenesis. Key enzyme involved in DNA replication and damage repair, shoot apical meristem (SAM) maintenance, and development. Involved in Okazaki fragments processing. Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)- dependent ATPase, 5'-3' helicase and endonuclease activities. While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is atypical: it cannot load [...] (1331 aa) |
| | A0A1I9LRA7 | HNH endonuclease. (254 aa) |
| | RNE | Ribonuclease E/G-like protein, chloroplastic; Involved in intercistronic processing of primary transcripts from chloroplast operons. The endonucleolytic activity of the enzyme depends on the number of phosphates at the 5' end, is inhibited by structured RNA, and preferentially cleaves A/U-rich sequences. Belongs to the RNase E/G family. (1001 aa) |
| | F4ITM2_ARATH | RBR-type E3 ubiquitin transferase. (384 aa) |
| | RSL1 | RBR-type E3 ubiquitin transferase. (398 aa) |
| | F13B15.3 | RBR-type E3 ubiquitin transferase. (603 aa) |
| | T8K22.15 | PIN domain-like family protein. (200 aa) |
| | F4IN73_ARATH | Ribonuclease III family protein. (77 aa) |
| | POP1 | Ribonuclease Ps. (826 aa) |
| | F4IJB6_ARATH | Beta-galactosidase related protein. (408 aa) |
| | CAN2 | Staphylococcal-like nuclease CAN2; Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. Possesses activity toward the single-stranded DNA, double-stranded DNA and RNA. May be involved in genomic DNA degradation during programmed cell death. (332 aa) |
| | PTD | Protein PARTING DANCERS; Required for chromosome segregation during meiosis. During diakinesis and prometaphase I, essential for the formation of class I meiotic crossovers and homologous recombination. Belongs to the ERCC1/RAD10/SWI10 family. (250 aa) |
| | F4ID71_ARATH | Reverse transcriptase-like protein. (144 aa) |
| | T23E23.25 | RNase H domain-containing protein. (353 aa) |
| | F4I5Q9_ARATH | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (257 aa) |
| | T27I1.2 | Ribonuclease H-like superfamily protein. (303 aa) |
| | F4J0R7_ARATH | Putative endonuclease or glycosyl hydrolase. (172 aa) |
| | F15L12.13 | RBR-type E3 ubiquitin transferase. (655 aa) |
| | SEN2 | tRNA-splicing endonuclease subunit Sen2-2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structur [...] (250 aa) |
| | RTL2 | Ribonuclease 3-like protein 2; Ribonuclease that cleaves double-stranded RNA (dsRNA). Required for 3'-external transcribed spacer (ETS) cleavage of the pre- rRNA precursors. May promote the production of 21 nucleotide small interfering RNA (siRNA) during post-transcriptional gene silencing (PTGS). (391 aa) |
| | MLM24.4 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (191 aa) |
| | DCL3 | Endoribonuclease Dicer homolog 3; Ribonuclease (RNase) III involved in RNA-mediated post- transcriptional gene silencing (PTGS). Involved in the processing of repeat-associated small interfering RNAs (ra-siRNAs, derived from heterochromatin and DNA repeats such as transposons) by cleaving small dsRNAs into 24 nucleotide ra-siRNAs. Plays a role in antiviral RNA silencing. Involved in the production of viral siRNAs derived from the cabbage leaf curl virus (CaLCuV) and tobacco rattle virus (TRV). Targeted by the viral silencing suppressor (VSR) protein 2b of the cucumber mosaic virus (CMV [...] (1580 aa) |
| | T15B3_50 | MutS2. (195 aa) |
| | NMAT3 | Nuclear intron maturase 3, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages; Belongs to the plant nuclear intron maturase (nMat) family. (723 aa) |
| | T28A8_40 | RBR-type E3 ubiquitin transferase. (346 aa) |
| | T12C14_160 | Putative endonuclease or glycosyl hydrolase. (200 aa) |
| | T15G18.90 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (170 aa) |
| | SEN1 | tRNA-splicing endonuclease subunit Sen2-1; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structur [...] (237 aa) |
| | F9K21.160 | RBR-type E3 ubiquitin transferase. (408 aa) |
| | F9K21.150 | RBR-type E3 ubiquitin transferase. (312 aa) |
| | PRORP1 | Proteinaceous RNase P 1, chloroplastic/mitochondrial; Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Preferentially cleaves at the unusual cleavage site, but also able to cleave at the classical cleavage site. Also involved in the maturation of mRNAs in mitochondria. (572 aa) |
| | PRORP2 | Proteinaceous RNase P 2; Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Preferentially binds precursor tRNAs containing short 5' leaders and 3' trailers. Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA) ; Belongs to the PPR family. P subfamily. (528 aa) |
| | T9D9.16 | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (368 aa) |
| | EMB1687 | Probable ribonuclease P/MRP protein subunit POP5; Essential protein required during embryogenesis. Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends (By similarity). Also a component of RNase MRP (By similarity). (151 aa) |
| | Q6DBN3_ARATH | tRNA-splicing endonuclease subunit. (254 aa) |
| | T29E15.4 | HNH endonuclease. (284 aa) |
| | Q6NQ97_ARATH | Putative endonuclease or glycosyl hydrolase. (489 aa) |
| | F4I4.70 | Carboxylate clamp-TPR protein (DUF1685). (192 aa) |
| | T7N22.8 | Ribonuclease III family protein. (237 aa) |
| | T10C21.110 | Putative endonuclease or glycosyl hydrolase. (191 aa) |
| | EME1A | Crossover junction endonuclease EME1A; Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meiot [...] (546 aa) |
| | Q84N39_ARATH | Endonuclease/glycosyl hydrolase. (106 aa) |
| | F3P11.21 | RBR-type E3 ubiquitin transferase. (418 aa) |
| | MWD22.2 | RNase H family protein. (322 aa) |
| | AGO9 | Protein argonaute 9; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates preferentially with small RNAs of 24 nucleotide in length with a 5' terminal adenosine. Interacts with 24 nucleotide sRNAs derived from transposable elements (TEs). Required to silence pericentrometric-located TEs i [...] (896 aa) |
| | RNJ | Ribonuclease J; Essential protein required during embryogenesis, especially in initiating and maintaining the organization of shoot apical meristems (SAMs), cotyledons, and hypocotyls. Involved in auxin-mediated pathways during embryogenesis. RNase that has both endonuclease and 5'-3' exonuclease activities. Involved in RNA surveillance to prevent overaccumulation of antisense RNA. Probably involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-li [...] (911 aa) |
| | MORC1 | Protein MICRORCHIDIA 1; Mediator of defense signaling triggered by distinct classes of R proteins. Required during hypersensitive response (HR) that confers disease resistance to turnip crinkle virus (TCV). Exhibits ATPase activity. Contributes to resistance against Pseudomonas syringae and Hyaloperonospora arabidopsidis, at early stages prior to cytosolic calcium ions Ca(2+) accumulation. Required for pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI), basal resistance, non-host resistance and systemic acquired resistance (SAR). Binds DNA/RNA in a non-specific manne [...] (635 aa) |
| | Q8GUH8_ARATH | Calcium-binding endonuclease/exonuclease/phosphatase family. (436 aa) |
| | F12A21.19 | Restriction endonuclease, type II-like superfamily protein. (355 aa) |
| | MOC1 | Holliday junction resolvase MOC1, chloroplastic; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Mediates chloroplast nucleoid segregation during chloroplast division. (273 aa) |
| | F19B11.23 | Translin family protein. (287 aa) |
| | F9F13.130 | Putative endonuclease or glycosyl hydrolase. (261 aa) |
| | YBEY | Endoribonuclease YBEY, chloroplastic; Endoribonuclease required for chloroplast ribosomal RNA (rRNA) processing and essential for normal growth and development. May be involved in maturation of both the 5' and 3' ends of 16S, 23S, and 4.5S rRNAs. Cleaves chloroplast rRNAs, mRNAs and tRNAs in vitro. Belongs to the endoribonuclease YbeY family. (584 aa) |
| | TRZ2 | tRNase Z TRZ2, chloroplastic; Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'- trailer from precursor tRNA. (354 aa) |
| | EXO1 | Exonuclease 1; Putative 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. May be involved in DNA mismatch repair (MMR) (By similarity). Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily. (735 aa) |
| | F6E21.70 | Endonuclease V family protein. (277 aa) |
| | ENDO3 | Endonuclease 3; Endonuclease that can use RNA and single-stranded DNA as substrates. In contradiction with cannot hydrolyze single-stranded DNA and does not cleave mismatches. (294 aa) |
| | TRZ1 | tRNase Z TRZ1; Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Can use bis-(p-nitophenyl) phosphate (bpNPP) as substrate. Involved in the processing of small nucleolar RNAs (snoRNAs). (280 aa) |
| | TRZ3 | tRNase Z TRZ3, mitochondrial; Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Can process the mitochondrial tRNA-like structures (t-elements). Involved in the processing of small nucleolar RNAs (snoRNAs). (890 aa) |
| | F4B12.5 | Uncharacterized exonuclease domain-containing protein At3g15140. (337 aa) |
| | IRE1B | Serine/threonine-protein kinase/endoribonuclease IRE1b; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes. Involved in organ growth regulation. Plays a role in plant immunity and abiotic stress responses. Required for ER stress- induced autophagy. Belongs to the protein kinase superfamily. [...] (881 aa) |
| | T10F20.10 | 5'-3' exonuclease family protein. (577 aa) |
| | RE1 | Retrovirus-related Pol polyprotein from transposon RE1. (1466 aa) |
| | DBR1 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis. Plays en essential role during embryogenesis. (418 aa) |
| | UVH3 | DNA repair protein UVH3; Putative single-stranded DNA endonuclease involved in nucleotide excision repair (NER) of UV- and oxidative damaged DNA. May make the 3'-incision step in NER. Seems to play a role in senescence program; Belongs to the XPG/RAD2 endonuclease family. XPG subfamily. (1479 aa) |
| | T6G21.20 | Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. (375 aa) |
| | IRE1A | Serine/threonine-protein kinase/endoribonuclease IRE1a; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes. Involved in organ growth regulation. Plays a role in plant immunity and abiotic stress responses. (841 aa) |
| | F28L5.12 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (213 aa) |
| | AGO7 | Protein argonaute 7; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for the processing of 21 nucleotide trans-acting siRNAs (ta-siRNAs) derived from TAS3a transcripts. Associates preferentially with the microRNA (miRNA) miR390 which guides the cleavage of TAS3 precursor RNA. Seems to [...] (990 aa) |
| | NMAT1 | Nuclear intron maturase 1, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages. Involved in the splicing of mitochondrial NAD4 transcripts. Required for trans-splicing of NAD1 intron 1 and also functions in cis-splicing of NAD2 intron 1 and NAD4 intron 2. Required for the regulation of fundamental metabolic pathways such as amino acid metabolism, triacylglycerol degradation and polysaccharide synthesis (cellulose and starch) during the early stage of plant growth. Imp [...] (711 aa) |
| | CPSF73-I | Cleavage and polyadenylation specificity factor subunit 3-I; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3'-end-processing endonuclease and also be involved in the histone 3'-end pre-mRNA processing. (693 aa) |
| | ENDO2 | Endonuclease 2; Endonuclease mostly active on RNA and ssDNA, and to a lower extent, on dsDNA. Can cleave mismatch regions in heteroduplex DNA containing single base pair mismatches or insertion/deletion bases. In contradiction with cannot hydrolyze single-stranded DNA and does not cleave mismatches. Belongs to the nuclease type I family. (290 aa) |
| | NMAT4 | Nuclear intron maturase 4, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in NAD1 pre-mRNA processing and maturation of introns 1, 3 and 4. Necessary for mitochondrial biogenesis during early developmental stages. Essential for respiratory holocomplex I biogenesis in mitochondria. (798 aa) |
| | MVP7.3 | Putative endonuclease or glycosyl hydrolase. (841 aa) |
| | MNL12.3 | Excinuclease ABC, C subunit, N-terminal. (170 aa) |
| | MFC16.13 | Ribonuclease H superfamily polynucleotidyl transferase. (108 aa) |
| | MYH9.5 | Putative endonuclease or glycosyl hydrolase. (924 aa) |
| | NMAT2 | Nuclear intron maturase 2, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in the splicing of mitochondrial COX2, NAD1 and NAD7 transcripts. Necessary for mitochondrial biogenesis during early developmental stages. (735 aa) |
| | RTL3 | Ribonuclease 3-like protein 3; Ribonuclease that cleaves double-stranded RNA (dsRNA). (957 aa) |
| | MUF9.6 | Antiporter/ drug transporter. (156 aa) |
| | NOB1 | RNA-binding NOB1-like protein; Essential protein required during embryogenesis and pollen development. Endonuclease cleaving pre-rRNA at the 3' end of the mature 18S rRNA (D-site); cleaves 20S pre-rRNA in the cytoplasm. Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. (602 aa) |
| | MBK20.8 | RBR-type E3 ubiquitin transferase. (316 aa) |
| | MAF19.21 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (657 aa) |
| | NFD2 | Protein NUCLEAR FUSION DEFECTIVE 2; Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus. (191 aa) |
| | T27I15_190 | Putative endonuclease or glycosyl hydrolase. (166 aa) |
| | T27I15_180 | Putative endonuclease or glycosyl hydrolase. (180 aa) |
| | T27I15_30 | Putative endonuclease or glycosyl hydrolase. (257 aa) |
| | UVH1 | DNA repair endonuclease UVH1; Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism). Involved in repair of UV light, and probably oxidative damage. The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site. In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs. May mediate the induction of a DNA-damage sensitive cell- cycle checkpoint during the G2 phase. (956 aa) |
| | GEN1 | Flap endonuclease GEN-like 1; Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA; Belongs to the XPG/RAD2 endonuclease family. GEN subfamily. (599 aa) |
| | F10E10.5 | Pentatricopeptide repeat-containing protein At5g46580, chloroplastic. (711 aa) |
| | Q9LSE9_ARATH | Ribonuclease H-like superfamily protein. (343 aa) |
| | F9K21.140 | Zinc finger (C3HC4-type RING finger) family protein. (503 aa) |
| | F9K21.80 | Uncharacterized protein F9K21.80. (201 aa) |
| | F9K21.70 | Reverse transcriptase-like protein. (211 aa) |
| | T17J13.170 | Putative endonuclease or glycosyl hydrolase. (279 aa) |
| | T17J13.160 | Putative endonuclease or glycosyl hydrolase. (673 aa) |
| | PEL2 | Protein PELOTA 2; Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily. (395 aa) |
| | GEN2 | Flap endonuclease GEN-like 2; Belongs to the XPG/RAD2 endonuclease family. GEN subfamily. (600 aa) |
| | RTL1-2 | Ribonuclease 3-like protein 1. (198 aa) |
| | F6A14.21 | HNH endonuclease domain-containing protein. (186 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1; Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism). The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site. In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs. In vitro, is involved in chromosomal recombination between tandem repeats in both direct and inverted orientations. May mediate the induction of a DNA-damage sensitive cell-cycle checkpoint during the G2 [...] (410 aa) |
| | F25C20.3 | Endonuclease/exonuclease/phosphatase family protein. (441 aa) |
| | F13D4.60 | Ribonuclease H2 subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity); Belongs to the RNase HII family. Eukaryotic subfamily. (296 aa) |
| | F26K24.16 | Inactive serine/threonine-protein kinase/endoribonuclease IRE1-like. (554 aa) |
| | F11F8_9 | Ribonuclease H-like superfamily protein. (484 aa) |
| | AGO3 | Protein argonaute 3; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression (By similarity). (1194 aa) |
| | AGO2 | Protein argonaute 2; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates mainly with siRNAs of 21 nucleotide in length and preferentially recruits small RNAs with a 5' terminal adenosine. Probably involved in antiviral RNA silencing. Associates with siRNA derived from cucumber mosaic virus [...] (1014 aa) |
| | RRP44A | Exosome complex exonuclease RRP44 homolog A; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Required for 5.8S rRNA intermediate processing and the degradation of 5' external transcribed spacer (5' ETS), a maturation by-product of rRNA synthesis. Is not involved in the degradation of turnip crinkle virus (TCV) RNA and significant virus resistance. Required for normal development of female gametophytes and early embryogenesis. (933 aa) |
| | F1P15.10 | RING/U-box protein with C6HC-type zinc finger protein. (99 aa) |
| | T1O3.17 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (221 aa) |
| | AGO5 | Protein argonaute 5; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates with siRNAs of various sizes, from 21-24 nucleotide in length and preferentially recruits small RNAs with a 5' terminal cytosine. Probably involved in antiviral RNA silencing. Associates with siRNAs derived from cuc [...] (997 aa) |
| | F3K23.18 | RBR-type E3 ubiquitin transferase. (468 aa) |
| | F11C10.15 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (160 aa) |
| | F13B15.2 | RBR-type E3 ubiquitin transferase. (373 aa) |
| | DCL1 | Endoribonuclease Dicer homolog 1; Ribonuclease (RNase) III involved in RNA-mediated post- transcriptional gene silencing (PTGS). Functions in the microRNAs (miRNAs) biogenesis pathway by cleaving primary miRNAs (pri-miRNAs) and precursor miRNAs (pre-miRNAs). Functions with DRB1/HYL1 and SERRATE proteins for accurate pri-miRNAs to miRNAs processing. Indirectly involved in the production of trans-acting small interfering RNAs (ta- siRNAs) derived from the TAS1, TAS2 or TAS3 endogenous transcripts by participating in the production of their initiating miRNAs. Involved in the processing of [...] (1909 aa) |
| | F16G16.7 | DNA mismatch repair protein MutS, type 2. (876 aa) |
| | F16A14.30 | Restriction endonuclease, type II-like superfamily protein. (303 aa) |
| | FAN1 | Fanconi-associated nuclease 1 homolog; Nuclease required for the repair of DNA interstrand cross- links (ICLs). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions (By similarity). May act upstream of the helicase RECQL4A and the ATPase RAD5A, which is involved in error-free post-replicative repair. Functions independently of MUS81 pathway, but in a similar pathway with RECQ4A, RAD5A and MFH1 in ICL repair. (891 aa) |
| | MUS81 | Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meioti [...] (659 aa) |
| | MORC2 | Protein MICRORCHIDIA 2; Mediator of defense signaling triggered by distinct classes of R proteins. Required during hypersensitive response (HR) that confers disease resistance to turnip crinkle virus (TCV). Contributes to resistance against Pseudomonas syringae and Hyaloperonospora arabidopsidis, at early stages prior to cytosolic calcium ions Ca(2+) accumulation. Required for pathogen-associated molecular pattern (PAMP)-triggered immunity, basal resistance, non-host resistance and systemic acquired resistance (SAR). Involved in RNA-directed DNA methylation (RdDM) as a component of the [...] (626 aa) |
| | MORC6 | Protein MICRORCHIDIA 6; Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. Together with SUVH2 and SUVH9, regulates the silencing of some transposable elements (TEs). Exhibits ATPase activity. May also be involved in the regulation of chromatin architecture/condensation to maintain gene silencing. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair (By similarity). Positive regulator of defense against the oomycete Hyaloperonospora arabidopsidis (Hpa). Belongs to th [...] (663 aa) |
| | F14I3.22 | Ribonuclease H superfamily polynucleotidyl transferase. (73 aa) |
| | Q3ECB5_ARATH | Ribonuclease H superfamily polynucleotidyl transferase. (100 aa) |
| | DCL2 | Endoribonuclease Dicer homolog 2; Ribonuclease (RNase) III involved in RNA-mediated post- transcriptional gene silencing (PTGS). Involved in the processing of natural small interfering RNAs (nat-siRNAs, derived from cis-natural antisense transcripts) by cleaving small dsRNAs into 24 nucleotide nat- siRNAs. Plays an essential role in transitive silencing of transgenes by processing secondary siRNAs. This pathway, which requires DCL4 and RDR6, amplifies silencing by using the target RNA as substrate to generate secondary siRNAs, providing an efficient mechanism for long- distance silenci [...] (1388 aa) |
| | AGO8 | Protein argonaute 8; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression (By similarity). (850 aa) |
| | Q3E8I3_ARATH | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (129 aa) |
| | Q3E7R1_ARATH | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (182 aa) |
| | T24G5.2 | Reverse transcriptase-like protein. (365 aa) |
| | PCMP-H40 | Pentatricopeptide repeat-containing protein At1g11290, chloroplastic; Involved in multiple sites RNA editing events in chloroplasts. Involved in the editing of the site 7 of ndhB (ndhB-7) and site 5 of ndhD (ndhD-5) transcripts, which are two plastid-encoded subunits of the chloroplast NAD(P)H dehydrogenase (NDH) complex. Involved in the editing of the site 3 of rpoB (rpoB-3) transcript. Required for the activity of the NDH complex of the photosynthetic electron transport chain. Possesses low endoribonuclease activity in vitro; Belongs to the PPR family. PCMP-H subfamily. (809 aa) |
| | Q2V3Q6_ARATH | tRNA-intron endonuclease. (118 aa) |
| | Q1PEI1_ARATH | RBR-type E3 ubiquitin transferase. (389 aa) |
| | Q1G3E3_ARATH | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (138 aa) |
| | Q1G367_ARATH | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (263 aa) |
| | PCMP-H51 | Pentatricopeptide repeat-containing protein At1g59720, chloroplastic/mitochondrial; Involved in multiple sites RNA editing events in chloroplasts. Involved in the editing of the site 2 of ndhB (ndhB-2) and site 3 of ndhD (ndhD-3) transcripts, which are two plastid-encoded subunits of the chloroplast NAD(P)H dehydrogenase (NDH) complex. Required for the activity of the NDH complex of the photosynthetic electron transport chain. (638 aa) |
| | RNL | tRNA ligase 1; Essential component of stress-response pathways entailing repair of RNA breaks with 2',3'-cyclic phosphate and 5'-OH ends. Tri-functional enzyme that repairs RNA breaks with 2',3'-cyclic-PO(4) and 5'-OH ends. The ligation activity requires three sequential enzymatic activities: opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester (CPDase activity), phosphorylation of the 5' terminus of the 3' half- tRNA in the presence of ATP (kinase activity) and ligation of the two tRNA halves in an ATP-dependent reaction (ligase activity). D [...] (1104 aa) |
| | DCL4 | Dicer-like protein 4; Ribonuclease (RNase) III involved in RNA-mediated post- transcriptional gene silencing (PTGS). Functions in the biogenesis of trans-acting small interfering RNAs (ta-siRNAs, derived from the TAS1, TAS2 or TAS3 endogenous transcripts) by cleaving small dsRNAs into 21- 24 nucleotide ta-siRNAs. Functions with the dsRNA-binding protein DRB4 in ta-siRNAs processing. Acts in the RDR6/SGS3/DCL4/AGO7 ta-siRNA pathway involved in leaf developmental timing. Plays a role in transitive silencing of transgenes by processing secondary siRNAs. This pathway, which requires DCL2 a [...] (1702 aa) |
| | ENDO1 | Endonuclease 1; Endonuclease that can use RNA, single-stranded and double- stranded DNA as substrates. Hydrolyzes single- stranded DNA and RNA without apparent specificity for bases during senescence. Endonuclease that recognizes and cleaves all types of mismatches with high efficiency, including heteroduplex double-stranded DNA. Maybe involved in programmed cell death (PCD) and senescence. (305 aa) |
| | F19B15.120 | Putative reverse transcriptase/RNA-dependent DNA polymerase. (575 aa) |
| | RNC1 | Ribonuclease III domain-containing protein RNC1, chloroplastic; Binds specific group II introns in chloroplasts and facilitates their splicing. Acts on both subgroup IIA and subgroup IIB introns. The substrates of the subgroup II also require the CRM domain proteins CAF1 or CAF2. Binds both single-stranded and double-stranded RNA non-specifically, but lacks endonuclease activity. Required for plastid ribosome biogenesis. (537 aa) |
| | MRE11 | Double-strand break repair protein MRE11; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (720 aa) |
| | AGO10 | Protein argonaute 10; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for reliable formation of primary and axillary shoot apical meristems. Specifies leaf adaxial identity by repressing the miR165 and miR166 microRNAs in the embryonic shoot apex, in the shoot apical meristem (SAM) and [...] (988 aa) |
| | F7A19.32 | Ribonuclease T2 family protein; Belongs to the RNase T2 family. (228 aa) |
| | OTP51 | Pentatricopeptide repeat-containing protein At2g15820, chloroplastic; Promotes the splicing of group II introns in chloroplasts. Required for the splicing of intron 2 of plastid ycf3 transcripts, a factor required for the assembly of photosystem I (PSI). Involved in the splicing of several other group-IIa introns. May be involved in the splicing of precursor forms of trnL, trnG, trnI, and trnA. Required for the assembly of PSI and PSII. (849 aa) |
| | F9B22.9 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (171 aa) |
| | PEL1 | Protein PELOTA 1; Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily. (378 aa) |
| | RE2 | Retrovirus-related Pol polyprotein from transposon RE2. (1456 aa) |
| | T4I9.8 | Uncharacterized protein AT4g03040. (92 aa) |
| | AGO4 | Protein argonaute 4; Together with RDM3, required for transcriptional gene silencing (TGS) by DNA methylation and repressive histone modifications (H3K9me2) of several chromatin loci. Component of the RISC complex that associate with the small interfering RNA (siRNA) pathway involved in direct cytosine methylation at endogenous DNA repeats. Forms a AGO4/NRPE1/siRNA complex in cajal body, facilitating its function in RNA-directed gene silencing of target loci. Required for CpNpG and asymmetric DNA methylation as well as histone H3 'Lys-9' methylation (H3K9me) at SUP and SN1 loci. May be [...] (924 aa) |
| | ARP | DNA-(apurinic or apyrimidinic site) lyase, chloroplastic; Repairs oxidative DNA damages, seems also to act as a redox factor. Is multifunctional and may be involved both in DNA repair and in the regulation of transcription. Exhibits apurinic/apyrimidinic (AP) endonuclease activity. Catalyzes the conversion of 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) to 3'-OH. May be involved in base excision repair in chloroplasts. According to a report, has a significant in vitro 3'-phosphatase activity. According to another report, has no in vitro 3'-phosphatase activity. Has a strong non [...] (536 aa) |
| | RNS3 | Ribonuclease 3; May remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting; Belongs to the RNase T2 family. (222 aa) |
| | RNS2 | Ribonuclease 2; May remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting. (259 aa) |
| | RNS1 | Ribonuclease 1; May remobilize phosphate, particularly when cells senesce or when phosphate becomes limiting. (230 aa) |
| | F1E22.12-2 | Putative ribonuclease H protein At1g65750. (620 aa) |
| | T16H5.30 | RBR-type E3 ubiquitin transferase. (532 aa) |
| | F13P17.16 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (292 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa) |
| | T8K22.5 | Ribonuclease H-like superfamily protein. (365 aa) |
| | NMA | Glycoside hydrolase family 28 protein / polygalacturonase (Pectinase) family protein. (664 aa) |
| | AGO6 | Protein argonaute 6; Involved in transcriptional gene silencing (TGS). Component of the RISC complex that associate with the small interfering RNA (siRNA) pathway involved in direct cytosine methylation at endogenous DNA repeats. Required for the accumulation of specific siRNAs derived from transgene and heterochromatin-related endogenous loci. Involved in RNA-directed DNA methylation (RdDM) at specific endogenous loci. Probably not required for the accumulation of siRNAs derived from transgene inverted repeats that induce post-transcriptional gene silencing (PTGS). Associates mainly w [...] (878 aa) |
| | DRB1 | Double-stranded RNA-binding protein 1; Double-stranded RNA-binding protein involved in RNA-mediated post-transcriptional gene silencing (PTGS). Functions in the microRNAs (miRNAs) biogenesis by assisting DICER-LIKE 1 (DCL1) in the accurate processing from primary miRNAs (pri-miRNAs) to miRNAs in the nucleus. Forms a complex with SERRATE (SE) and DCL1 to promote accurate processing of pri-miRNAs by DCL1. Binds and assist DCL1 for accurate processing of precursor miRNAs (pre-miRNA). Indirectly involved in the production of trans-acting small interfering RNAs (ta-siRNAs) derived from the [...] (419 aa) |
| | AGO1 | Protein argonaute 1; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Requires DRB1 for directional loading of the small RNA duplex (guide stand and passenger strand) onto RISC for passenger strand degradation. Unlike animal RISC that associates in high molecular weight complex, Arabidopsis RISC i [...] (1048 aa) |
| | F19N2.50 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (183 aa) |
| | MKM21.10 | Restriction endonuclease, type II-like superfamily protein. (1272 aa) |
| | MIJ24.14 | Putative endonuclease or glycosyl hydrolase. (76 aa) |
| | K15E6.15 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (192 aa) |
| | MORC4 | Protein MICRORCHIDIA 4; Exhibits ATPase activity. Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. Probably involved in DNA repair. Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. May also be involved in the regulation of chromatin architecture to maintain gene silencing. Together with MORC7, acts to suppress a wide set of non- methylated protein-coding genes, especially involved in pathogen response. Positive regulator of defense against the oomycete Hyaloperonospora arabidopsidis (Hpa). (800 aa) |
| | MXM12.5 | annotation not available (1194 aa) |
| | F4K7A8_ARATH | Non-LTR retrolelement reverse transcriptase-like protein. (176 aa) |
| | K12B20.10 | RBR-type E3 ubiquitin transferase. (444 aa) |
