STRINGSTRING
F4JPT1_ARATH F4JPT1_ARATH IWS1 IWS1 BSK11 BSK11 BSK7 BSK7 BSK4 BSK4 BSK9 BSK9 B'GAMMA B'GAMMA BZR1 BZR1 BPG2 BPG2 BSK3 BSK3 WRKY54 WRKY54 BSK1 BSK1 BEH2 BEH2 SERK1 SERK1 PRE3 PRE3 BSK8 BSK8 BSK5 BSK5 PRE1 PRE1 BKI1 BKI1 TOR TOR BSK10 BSK10 BZR2 BZR2 BSU1 BSU1 BSK2 BSK2 CDG1 CDG1 B'ETA B'ETA RALF23 RALF23 B'ZETA B'ZETA TTL-2 TTL-2 PAR2 PAR2 WRKY70 WRKY70 SCPL24 SCPL24 IBL1 IBL1 LFG2 LFG2 BSK6 BSK6 BHLH150 BHLH150 BEH1 BEH1 FER FER BSL3 BSL3 T23A1.3 T23A1.3 TTL3 TTL3 BSL2 BSL2 PAR1 PAR1 WRKY46 WRKY46 SERK4 SERK4 IBH1 IBH1 KIB4 KIB4 KIB2 KIB2 KIB1 KIB1 YUC8 YUC8 BRH1 BRH1 VIK VIK SERK2 SERK2 BRL2 BRL2 HBI1 HBI1 BEH4 BEH4 KIB3 KIB3 B'THETA B'THETA BSL1 BSL1 BSK12 BSK12 MYB56 MYB56 MAKR1 MAKR1 ASK9 ASK9 ASK7 ASK7 ASK6-2 ASK6-2 SCPL22 SCPL22 PBL7 PBL7 GRF2 GRF2 T6D20.3 T6D20.3 GRF6 GRF6 GRF10 GRF10 CYP18-3 CYP18-3 SCPL23 SCPL23 IWS2 IWS2 BEH3 BEH3 BIA1 BIA1 T23A1.2 T23A1.2 BRI1 BRI1 GCR1 GCR1 B'BETA B'BETA B'ALPHA B'ALPHA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F4JPT1_ARATHInterleukin-1 receptor-associated kinase 4 protein. (153 aa)
IWS1Protein IWS1 homolog 1; Transcription factor involved in RNA polymerase II (RNAPII) transcription regulation. Involved in transcription elongation. May function at post-recruitment and elongation steps of transcription. May be recruited by BZR2/BES1 to target genes and promote their expression during transcription elongation process. Required for brassinosteroid (BR)-induced gene expression. Required the for regulation of numerous nitrogen-responsive genes in roots. Acts in roots to repress NRT2.1 transcription in response to high nitrogen supply. This repression is associated with an [...] (502 aa)
BSK11Serine/threonine-protein kinase BSK11; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (507 aa)
BSK7Serine/threonine-protein kinase BSK7; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK5, BSK6 and BSK8. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (487 aa)
BSK4Serine/threonine-protein kinase BSK4; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK6, BSK7 and BSK8. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (483 aa)
BSK9Kinase with tetratricopeptide repeat domain-containing protein. (492 aa)
B'GAMMASerine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' gamma isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that negatively regulates brassinosteroid signaling by dephosphorylating and inactivating BRI1 in the cytoplasm. Seems to be functionally connected with CPR5 and may mediate the negative regulation of defense reactions and senescence under low irradiances. [...] (522 aa)
BZR1Protein BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2). (336 aa)
BPG2GTP-binding protein BRASSINAZOLE INSENSITIVE PALE GREEN 2, chloroplastic; Required for brassinosteroid- (BR) mediated post- transcriptional and translational regulation in the chloroplast, including accumulation of chloroplast rRNA. Involved in chloroplast differentiation. (660 aa)
BSK3Serine/threonine-protein kinase BSK3; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Mediates signal transduction from BRI1 by functioning as substrate of BRI1. Functions redundantly with BSK4, BSK6, BSK7 and BSK8. (489 aa)
WRKY54Probable WRKY transcription factor 54; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). Together with WRKY70, negative regulator of developmental senescence, probably via the regulation of several senescence-associated markers genes. Positive regulator of EDS1-dependent defense against E.amylovora. In collaboration with WRKY70, prevents stomatal closure and, consequently, osmotic stress tolerance. Together with WRKY46 and WRKY70, promotes brassinosteroid (BR)- regulated plant [...] (346 aa)
BSK1Serine/threonine-protein kinase BSK1; Serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Mediates signal transduction from BRI1 by functioning as substrate of BRI1. Functions as a positive regulator of plant immunity. May be involved in the regulation of pattern-triggered immunity (PTI) downstream of the flagellin receptor FLS2. Possesses kinase activity in vitro. Kinase activity is required for its function in innate immunity. (512 aa)
BEH2BES1/BZR1 homolog protein 2. (318 aa)
SERK1Somatic embryogenesis receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Phosphorylates BRI1 on 'Ser-887' and CDC48 on at least one threonine residue and on 'Ser-41'. Confers embryogenic competence. Acts redundantly with SERK2 as a control point for sporophytic development controlling male gametophyte production. Involved in the brassinolide signaling pathway. (625 aa)
PRE3Transcription factor PRE3; Atypical and probable non DNA-binding bHLH transcription factor required for MONOPTEROS-dependent root initiation in embryo. Promotes the correct definition of the hypophysis cell division plane. Transcriptionally controlled by MONOPTEROS. Moves from its site of synthesis in pro-embryos cells into the hypophysis. Regulates brassinosteroid (BR) signaling by sequestering negative BR signaling components. May function as positive regulator of gibberellin signaling. May play a role in the regulation of light signaling and possibly auxin signaling. (93 aa)
BSK8Serine/threonine-protein kinase BSK8; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK4, BSK6 and BSK7. Involved in the regulation of sucrose-phosphate synthase 1 (SPS1) in the context of sucrose resuply after starvation. Activates BSL2, a phosphatase that may dephosphorylate SPS1, leading to the activation of SPS1 ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (487 aa)
BSK5Serine/threonine-protein kinase BSK5; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Involved in abiotic stress tolerance. Required for salt stress and abscisic acid-mediated drought stress tolerance. (489 aa)
PRE1Transcription factor PRE1; Atypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development. Binds IBH1, forming a pair of antagonistic bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation. Regulates light responses by binding and inhibiting the activity of the bHLH transcription factor HFR1, a critical regulator of light signaling and shade avoidance. May have a regulatory role in various aspects of gibberellin-dependent growth an [...] (92 aa)
BKI1BRI1 kinase inhibitor 1; Negative regulator of brassinosteroid signaling. When associated to the membrane, limits the interaction of BRI1 with BAK1 by binding to the kinase-inactive form of BRI1. (337 aa)
TORSerine/threonine-protein kinase TOR; Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival. Involved in modulating the transition from heterotrophic [...] (2481 aa)
BSK10Kinase with tetratricopeptide repeat domain-containing protein. (499 aa)
BZR2Protein BRASSINAZOLE-RESISTANT 2; Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N- terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C- terminal domain is probably involved in transcriptional activation. Recruits the transcription elongation factor IWS1 to control BR- regulated gene expression. Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-reg [...] (335 aa)
BSU1Serine/threonine-protein phosphatase BSU1; Phosphatase that acts as a positive regulator of brassinosteroid (BR) signaling. Dephosphorylates BES1, a transcription factor that regulates the expression of BR-response genes, thereby playing an important role in the regulation of response to BRs. Inactivates the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200'. (793 aa)
BSK2Serine/threonine-protein kinase BSK2; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Mediates signal transduction from BRI1 by functioning as substrate of BRI1. (489 aa)
CDG1Serine/threonine-protein kinase CDG1; Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth. Mediates BR signal transduction from BRI1 receptor kinase to BSU1 phosphatase. After activation by phosphorylation at Ser-234 by BRI1, CDG1 phosphorylates BSU1 at 'Ser-764' in the phosphatase domain, increasing the ability of BSU1 to inactivate the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200'. The full kinase activity of CDG1 is required for its biological function. (432 aa)
B'ETASerine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' eta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). The holoenzyme composed of PP2AA1, PP2A4 and B'ETA acts as negative regulator of plant innate immunity by controlling BAK1 phosphorylation state and activation in surface-localized immune receptor complexes. Required for the formation of the PP2A holoenzyme that negatively regulates brassinosteroid signalin [...] (510 aa)
RALF23Rapid alkalinization factor 23; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity). Regulates negatively brassinolide (BL)-mediated signaling pathway (e.g. BL-induced hypocotyl elongation and branching limitation). (138 aa)
B'ZETASerine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' zeta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). The holoenzyme composed of PP2AA1, PP2A4 and B'ZETA acts as negative regulator of plant innate immunity by controlling BAK1 phosphorylation state and activation in surface-localized immune receptor complexes. Required for the formation of the PP2A holoenzyme that negatively regulates brassinosteroid signal [...] (546 aa)
TTL-22-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Involved in the last two steps of the degradation of uric acid, i.e. the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) and its stereoselective decarboxylation to (S)-allantoin. Might function as a negative regulator to modulate brassinosteroid-mediated plant growth; In the C-terminal section; belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (324 aa)
PAR2Transcription factor PAR2; Atypical bHLH transcription factor that acts as negative regulator of a variety of shade avoidance syndrome (SAS) responses, including seedling elongation and photosynthetic pigment accumulation. Acts as direct transcriptional repressor of two auxin-responsive genes, SAUR15 and SAUR68. May function in integrating shade and hormone transcriptional networks in response to light and auxin changes. (118 aa)
WRKY70Probable WRKY transcription factor 70; Transcription factor involved in senescence, biotic and abiotic stress responses by modulating various phytohormones signaling pathways. Interacts specifically with the W box (5'- (T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Binds to the 5'-[CT]GACTTTT-3' motif in promoters of target genes to induce their expression. Plays an important but not indispensable role in jasmonate and salicylic acid signaling. Regulates positively the salicylic acid (SA)-mediated signal pathway, but negatively the jasmo [...] (294 aa)
SCPL24Serine carboxypeptidase 24 chain A; Active serine carboxypeptidase with broad substrate preference, including basic and hydrophilic groups. Processes a protein involved in an early event in the brassinosteroid signaling pathway. (465 aa)
IBL1Transcription factor IBH1-like 1; Functions redundandly with IBH1/BHLH158 in a regulation node known as the incoherent feed-forward loop (FFL). Acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling. (180 aa)
LFG2Protein LIFEGUARD 2; Regulates the brassinosteroid (BR) signaling pathway that mediates cell elongation and organ morphogenesis. (Microbial infection) May prevent cell death upon A.alternata f.sp. lycopersici (AAL) toxin treatment. (239 aa)
BSK6Serine/threonine-protein kinase BSK6; Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK4, BSK7 and BSK8. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (490 aa)
BHLH150Transcription factor bHLH150; Atypical bHLH transcription factor probably unable to bind DNA. Negatively regulates brassinosteroid signaling. (211 aa)
BEH1BES1/BZR1 homolog protein 1. (276 aa)
FERReceptor-like protein kinase FERONIA; Receptor-like protein kinase that mediates the female control of male gamete delivery during fertilization, including growth cessation of compatible pollen tubes ensuring a reproductive isolation barriers, by regulating MLO7 subcellular polarization upon pollen tube perception in the female gametophyte synergids. Required for cell elongation during vegetative growth, mostly in a brassinosteroids- (BR-) independent manner. Acts as an upstream regulator for the Rac/Rop-signaling pathway that controls ROS-mediated root hair development. Seems to regul [...] (895 aa)
BSL3Serine/threonine-protein phosphatase BSL3; Phosphatase involved in elongation process, probably by acting as a regulator of brassinolide signaling. (1006 aa)
T23A1.3Protein kinase superfamily protein. (328 aa)
TTL3Inactive TPR repeat-containing thioredoxin TTL3; Involved in osmotic and salt stress tolerance. May play a role in the control of meristematic cell size during osmotic stress. May function as an adaptor protein for BRL2 and may be required for signaling affecting leaf vascular tissue pattern formation. (691 aa)
BSL2Serine/threonine-protein phosphatase BSL2; Phosphatase involved in elongation process, probably by acting as a regulator of brassinolide signaling. Belongs to the PPP phosphatase family. BSU subfamily. (1018 aa)
PAR1Transcription factor PAR1; Atypical bHLH transcription factor that acts as negative regulator of a variety of shade avoidance syndrome (SAS) responses, including seedling elongation and photosynthetic pigment accumulation. Acts as direct transcriptional repressor of two auxin-responsive genes, SAUR15 and SAUR68. May function in integrating shade and hormone transcriptional networks in response to light and auxin changes. (118 aa)
WRKY46Probable WRKY transcription factor 46; Transcription factor involved in the regulation of osmotic stress responses and stomatal movement. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora. Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2. Together with WRKY54 and WRKY70, prom [...] (295 aa)
SERK4Somatic embryogenesis receptor kinase 4; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Positively regulates the BR-dependent plant growth pathway and negatively regulates the BR-independent cell- death pathway. (620 aa)
IBH1Transcription factor IBH1; Atypical and probable non DNA-binding bHLH transcription factor that acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling. Is able to form heterodimer with BHLH49, thus inhibiting DNA binding of BHLH49, which is a transcriptional activator that regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds and inhibits HBI1, a positive regulator of cell elongation that directly binds to the promoters and activated [...] (156 aa)
KIB4F-box protein KIB4; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Required for brassinosteroid (BR) signal transduction. Mediates ASK7/BIN2/SK21 inactivation both by competing with substrate binding (e.g. BZR1) and by promoting its ubiquitination and subsequent proteasomal degradation. (393 aa)
KIB2F-box protein KIB2; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Required for brassinosteroid (BR) signal transduction. Mediates ASK7/BIN2/SK21 inactivation both by competing with substrate binding (e.g. BZR1) and by promoting its ubiquitination and subsequent proteasomal degradation. (442 aa)
KIB1F-box/kelch-repeat protein KIB1; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Required for brassinosteroid (BR) signal transduction. Mediates ASK7/BIN2/SK21 inactivation both by competing with substrate binding (e.g. BZR1) and by promoting its ubiquitination and subsequent proteasomal degradation. (382 aa)
YUC8Probable indole-3-pyruvate monooxygenase YUCCA8; Involved in auxin biosynthesis. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in roots. (426 aa)
BRH1Brassinosteroid-responsive RING protein 1; May be involved in the brassinosteroids (BRs) signaling pathway and regulate the growth and development of rosette leaves. Seems to prevent over development of leaves and inflorescence stems. (170 aa)
VIKVH1-interacting kinase. (438 aa)
SERK2Somatic embryogenesis receptor kinase 2; Serine/threonine-kinase involved in brassinosteroid-dependent and -independent signaling pathways. Acts redundantly with SERK1 as a control point for sporophytic development controlling male gametophyte production. (628 aa)
BRL2Serine/threonine-protein kinase BRI1-like 2; Receptor with a serine/threonine-protein kinase activity, which may transduce extracellular spatial and temporal signals into downstream cell differentiation responses in provascular and procambial cells. In contrast to BRI1, BRL1 and BRL3, it does not bind brassinolide. (1143 aa)
HBI1Transcription factor HBI1; Atypical bHLH transcription factor that acts as positive regulator of cell elongation downstream of multiple external and endogenous signals by direct binding to the promoters and activation of the two expansin genes EXPA1 and EXPA8, encoding cell wall loosening enzymes. Transcriptional activity is inhibited when binding to the bHLH transcription factor IBH1. (337 aa)
BEH4BES1/BZR1 homolog protein 4. (325 aa)
KIB3F-box protein KIB3; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Required for brassinosteroid (BR) signal transduction. Mediates ASK7/BIN2/SK21 inactivation both by competing with substrate binding (e.g. BZR1) and by promoting its ubiquitination and subsequent proteasomal degradation. (450 aa)
B'THETASerine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Associates with the serine/threonine-protein phosphatase PP2A catalytic subunit C and regulatory subunit A to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Required for the formation of the PP2A holoenzym [...] (492 aa)
BSL1Serine/threonine-protein phosphatase BSL1; Phosphatase involved in elongation process, probably by acting as a regulator of brassinolide signaling. (881 aa)
BSK12Probable inactive receptor-like kinase BSK12; Probable inactive protein kinase that activates the YODA MAP kinase cascade, which regulates the asymmetric first division and embryo polarity, by promoting the elongation of the zygote and the development of its basal daughter cell into the extra-embryonic suspensor. Acts as an adapter at the plasma membrane, possibly by recruiting and binding an activator. (465 aa)
MYB56Transcription factor MYB56; Acts as a cell-specific local repressor of quiescent center (QC) self-renewal by cell divisions in the primary root. Counteracts brassinosteroid (BR)-mediated cell division in the QC cells. Regulates maternally seed size, especially before the heart stage, promoting both endothelial cells expansion and cell number in the outer integument layer of the seed coat. Modulates the expression of genes involved in cell wall metabolism such as cell division and expansion. Negative regulator of flowering via the repression of FT transcription. (323 aa)
MAKR1Probable membrane-associated kinase regulator 1; May negatively regulate brassinosteroid signaling. (341 aa)
ASK9Shaggy-related protein kinase iota; Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in vitro. May mediate extracellular signals to regulate transcription in differentiating cells (By similarity). (407 aa)
ASK7Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...] (380 aa)
ASK6-2Shaggy-related protein kinase zeta; May mediate extracellular signals to regulate transcription in differentiating cells. (412 aa)
SCPL22Serine carboxypeptidase-like 22; Probable carboxypeptidase; Belongs to the peptidase S10 family. (464 aa)
PBL7Probable serine/threonine-protein kinase PBL7; Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth. Phosphorylates both BSU1 and BSL1 in vitro. (378 aa)
GRF214-3-3-like protein GF14 omega; Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes; Belongs to the 14-3-3 family. (259 aa)
T6D20.3Chaperone DnaJ-domain superfamily protein. (263 aa)
GRF614-3-3-like protein GF14 lambda; Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes (By similarity). Specific negative regulator of slow- vacuolar (SV) ion channel. Mediates F-actin dynamics possibly through inhibiting ADF1 phosphorylation. Negative regulator of freezing tolerance that modulates cold-responsive C-repeat-binding factors (CBF) DREB1A AND DREB1B proteins stability by facilitating their ubiquitin-mediated degradation when activated by CRPK1-mediated phosophorylation in freezing conditions. (248 aa)
GRF1014-3-3-like protein GF14 epsilon; Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. (254 aa)
CYP18-3Peptidyl-prolyl cis-trans isomerase CYP18-3; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in de-etiolation. Reduces the sensitivity to brassinosteroids by decreasing somehow the abundance of the partially dephosphorylated form of BES1. Triggers the activation of bacterial AvrRpt2 protease activity upon infection by P.syringae. Activated AvrRpt2 confers virulence in plant lacking the RPS2 resistance gene. In plants expressing RPS2, the AvrRpt2-mediated degradation of RIN4 activates RPS2, w [...] (172 aa)
SCPL23Putative serine carboxypeptidase-like 23; Probable carboxypeptidase. (454 aa)
IWS2Protein IWS1 homolog 2; Transcription factor involved in RNA polymerase II (RNAPII) transcription regulation. Involved in transcription elongation. May function at post-recruitment and elongation steps of transcription. Belongs to the IWS1 family. (406 aa)
BEH3BES1/BZR1 homolog protein 3. (284 aa)
BIA1BAHD acyltransferase BIA1; Monitors brassinosteroids (BR) responses and homeostasis, particularly in the root and hypocotyl in darkness. Promotes flavonoid biosynthesis. Belongs to the plant acyltransferase family. (435 aa)
T23A1.2Interleukin-1 receptor-associated kinase 4 protein. (95 aa)
BRI1Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...] (1196 aa)
GCR1G-protein coupled receptor 1; Together with GPA1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate(IP(3)) as a second messenger. Acts as a negative regulator of GPA1-mediated abscisic acid (ABA) responses in guard cells, and together with GPA1 and GB1 during seed germination and early seedling development. Promotes PI-PLC activity and IP(3) accumulation. Involved in the blue light (BL) signaling. Together with GPA1 and ADT3, required for BL- mediated synthesis of phenylpy [...] (326 aa)
B'BETASerine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1. (499 aa)
B'ALPHASerine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' alpha isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1. (495 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (38%) [HD]