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UGT80B1 UGT80B1 SQE1 SQE1 CYP51G1 CYP51G1 UGT80A2 UGT80A2 HDF7 HDF7 SMT1 SMT1 DWF5 DWF5 FK FK 3BETAHSD/D1 3BETAHSD/D1 PMK PMK SMT3 SMT3 SQE3 SQE3 SMO2-2 SMO2-2 SMO1-1 SMO1-1 CER3 CER3 Q6ID26_ARATH Q6ID26_ARATH 3BETAHSD/D2 3BETAHSD/D2 FPS2 FPS2 SMT2 SMT2 STE1 STE1 SMO1-2 SMO1-2 FPS1 FPS1 HMGS HMGS SQS1 SQS1 MK MK HMG2 HMG2 HMG1 HMG1 SQE2 SQE2 ERG28 ERG28 SQS2 SQS2 SQE5 SQE5 SQE4 SQE4 SQE6 SQE6 CYP710A2 CYP710A2 CYP710A1 CYP710A1 CYP710A4 CYP710A4 CYP710A3 CYP710A3 SMO2-1 SMO2-1 MVD1 MVD1 3BETAHSD/D3 3BETAHSD/D3 T7I23.9 T7I23.9 CER1 CER1 F13M22.20 F13M22.20 MVD2 MVD2 SMO1-3 SMO1-3 HYD1 HYD1
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UGT80B1Sterol 3-beta-glucosyltransferase UGT80B1; Involved in the biosynthesis of sterol glucosides. Catalyzes the synthesis of steryl glycosides (SGs) and acyl steryl glycosides (ASGs) which are the most abundant sterol derivatives in higher plants. Can act on several sterols like sitosterol, campesterol and stigmasterol. Is required for embryonic development, seed suberin accumulation, cutin formation and flavanoid accumulation in the seed coat. Both UGT80A2 and UGT80B1 are required for the normal production of SGs and ASGs in seeds; Belongs to the glycosyltransferase 28 family. (615 aa)
SQE1Squalene epoxidase 1; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. Can produce not only oxidosqualene, but also 2,3:22,23-dioxidosqualene. Main squalene epoxidase in the root. Sqe1 mutants may show defects in membrane lipid rafts, impairing the correct localization of RHD2 NADPH oxidase and the proper polarized production of ROS. (531 aa)
CYP51G1Sterol 14-demethylase; Involved in sterol biosynthesis. Catalyzes the 14-alpha demethylation of obtusifoliol to 4 alpha-methyl-5 alpha-ergosta- 8,14,24(28)-trien-3 beta-ol. (488 aa)
UGT80A2Sterol 3-beta-glucosyltransferase UGT80A2; Involved in the biosynthesis of sterol glucosides. Catalyzes the synthesis of steryl glycosides (SGs) and acyl steryl glycosides (ASGs) which are the most abundant sterol derivatives in higher plants. Can act on several sterols like sitosterol, campesterol and stigmasterol. Both UGT80A2 and UGT80B1 are required for the normal production of SGs and ASGs in seeds. (637 aa)
HDF7Putative Delta(7)-sterol-C5(6)-desaturase 2; Belongs to the sterol desaturase family. (279 aa)
SMT1Cycloartenol-C-24-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of cycloartenol to form 24-methylene cycloartenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (336 aa)
DWF57-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). Lesions in the gene coding for the enzyme cause dwarfism; Belongs to the ERG4/ERG24 family. (432 aa)
FKDelta(14)-sterol reductase; Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta- 8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Required for cell division and expansion and is involved in proper organization of the embryo. (369 aa)
3BETAHSD/D13beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1. (439 aa)
PMKPhosphomevalonate kinase, peroxisomal. (505 aa)
SMT324-methylenesterol C-methyltransferase 3; Catalyzes the methyl transfer from S-adenosyl-methionine to the methylene group of 24-methylene lophenol to form 24-ethylidene lophenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (359 aa)
SQE3Squalene epoxidase 3; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. Can produce not only oxidosqualene, but also 2,3:22,23-dioxidosqualene. (525 aa)
SMO2-2Methylsterol monooxygenase 2-2; Non-heme iron oxygenase involved in sterols biosynthesis. 24- ethylidenelophenol and 24-ethyllophenol are the preferred substrates. (266 aa)
SMO1-1Methylsterol monooxygenase 1-1; Non-heme iron oxygenase involved in sterols biosynthesis. 4,4-dimethyl-9-beta,19-cyclopropylsterols such as 24- methylenecycloartanol are the preferred substrates. Belongs to the sterol desaturase family. (298 aa)
CER3Very-long-chain aldehyde decarbonylase CER3; Involved in cuticule membrane and wax production, and in the typhine and sopropollenin biosynthesis of pollen. Core components of a very-long-chain alkane synthesis complex. May be the fatty acid reductase responsible for aldehyde formation. Belongs to the sterol desaturase family. (632 aa)
Q6ID26_ARATHFAD/NAD(P)-binding oxidoreductase family protein. (121 aa)
3BETAHSD/D23beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2. (564 aa)
FPS2Farnesyl pyrophosphate synthase 2; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate; Belongs to the FPP/GGPP synthase family. (342 aa)
SMT224-methylenesterol C-methyltransferase 2; Catalyzes the methyl transfer from S-adenosyl-methionine to the methylene group of 24-methylene lophenol to form 24-ethylidene lophenol. (361 aa)
STE1Delta(7)-sterol-C5(6)-desaturase 1; Involved in the biosynthesis of sitosterol and campesterol, a precursor of growth-promoting brassinosteroids. (281 aa)
SMO1-2Methylsterol monooxygenase 1-2; Non-heme iron oxygenase involved in sterols biosynthesis. 4,4-dimethyl-9-beta,19-cyclopropylsterols such as 24- methylenecycloartanol are the preferred substratess; Belongs to the sterol desaturase family. (299 aa)
FPS1Farnesyl pyrophosphate synthase 1, mitochondrial; Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. (384 aa)
HMGSHydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Devoided of acetoacetyl-CoA thiolase (AACT) activity. Required for the development of both tapetosomes and elaioplasts in tapetal cells and for pollen viability during pollen tube elongation; Belongs to the thiolase-like superfamily. HMG-CoA synthase family. (461 aa)
SQS1Squalene synthase 1. (410 aa)
MKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (378 aa)
HMG23-hydroxy-3-methylglutaryl-coenzyme A reductase 2; Catalyzes the synthesis of mevalonate. The specific precursor of all isoprenoid compounds present in plants. Belongs to the HMG-CoA reductase family. (562 aa)
HMG13-hydroxy-3-methylglutaryl-coenzyme A reductase 1; Catalyzes the synthesis of mevalonate, the specific precursor of all isoprenoid compounds present in plants. (592 aa)
SQE2Squalene epoxidase 2, mitochondrial; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. Produces primarily oxidosqualene. (585 aa)
ERG28Ergosterol biosynthetic protein 28. (129 aa)
SQS2Inactive squalene synthase 2; Belongs to the phytoene/squalene synthase family. (413 aa)
SQE5Squalene epoxidase 5; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. (516 aa)
SQE4Squalene epoxidase 4; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. (516 aa)
SQE6Squalene epoxidase 6; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. (517 aa)
CYP710A2Cytochrome P450 710A2; Required to form the C-22 double bond in the sterol side chain. Possesses in vitro C-22 desaturase activity toward 24-epi- campesterol and beta-sitosterol and produces brassicasterol and stigmasterol, respectively. No activity with campesterol. (499 aa)
CYP710A1Cytochrome P450 710A1; Required to form the C-22 double bond in the sterol side chain. Possesses in vitro C-22 desaturase activity toward beta- sitosterol and produces stigmasterol. No activity with campesterol. Belongs to the cytochrome P450 family. (495 aa)
CYP710A4Cytochrome P450 710A4; Required to form the C-22 double bond in the sterol side chain. Possesses C-22 desaturase activity toward beta-sitosterol and produces stigmasterol; Belongs to the cytochrome P450 family. (493 aa)
CYP710A3Cytochrome P450 710A3; Required to form the C-22 double bond in the sterol side chain. Possesses in vitro C-22 desaturase activity toward beta- sitosterol and produces stigmasterol. (493 aa)
SMO2-1Methylsterol monooxygenase 2-1; Non-heme iron oxygenase involved in sterols biosynthesis. 24- ethylidenelophenol and 24-ethyllophenol are the preferred substrates. (272 aa)
MVD1Diphosphomevalonate decarboxylase MVD1, peroxisomal; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Is specific for (R)-5- diphosphomevalonate (MVAPP). The catalytic efficiency with (R)-5- phosphomevalonate (MVAP) as substrate is 10000-fold lower than for MVAPP. Can complement a yeast mutant defective in MVD activity. (412 aa)
3BETAHSD/D33beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3; Belongs to the 3-beta-HSD family. (561 aa)
T7I23.9Protein CER1-like 1. (627 aa)
CER1Very-long-chain aldehyde decarbonylase CER1; Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes. Core component of a very-long-chain alkane synthesis complex. Involved in epicuticular wax biosynthesis and pollen fertility; Belongs to the sterol desaturase family. (625 aa)
F13M22.20Protein CER1-like 2. (613 aa)
MVD2Diphosphomevalonate decarboxylase MVD2, peroxisomal; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Is specific for (R)-5-diphosphomevalonate (MVAPP). The catalytic efficiency with (R)-5-phosphomevalonate (MVAP) as substrate is 10000- fold lower than for MVAPP; Belongs to the diphosphomevalonate decarboxylase family. (419 aa)
SMO1-3Methylsterol monooxygenase 1-3; Non-heme iron oxygenase involved in sterols biosynthesis. 4,4-dimethyl-9-beta,19-cyclopropylsterols such as 24- methylenecycloartanol are the preferred substrates; Belongs to the sterol desaturase family. (291 aa)
HYD1Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers; Belongs to the EBP family. (223 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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