STRINGSTRING
ACP2 ACP2 LHCA4 LHCA4 TCTP1 TCTP1 FFC FFC DRT112 DRT112 FAD6 FAD6 GSTF2 GSTF2 PSAN PSAN LHCA1 LHCA1 LHCB4.1 LHCB4.1 THI1 THI1 FER1 FER1 Lhb1B2 Lhb1B2 Lhb1B1 Lhb1B1 VDE1 VDE1 PSBP1 PSBP1 F4L23.31 F4L23.31 PDE334 PDE334 RBL11 RBL11 T6D22.20 T6D22.20 PGRL1A PGRL1A CYB561A CYB561A ALB3 ALB3 CURT1B CURT1B T16L1.30 T16L1.30 EMB3003 EMB3003 LFNR1 LFNR1 T2K12.1 T2K12.1 LHCB6 LHCB6 T20L15.20 T20L15.20 MSBP2 MSBP2 GPT1 GPT1 AIG2B AIG2B PSAE2 PSAE2 psaD1 psaD1 LHCB3 LHCB3 PSAE1 PSAE1 PSAD2 PSAD2 TRX-M4 TRX-M4 PSAF PSAF LHCB2.1 LHCB2.1 PSBX PSBX PSAL PSAL LHCA3 LHCA3 F11M15.26 F11M15.26 LHCA2 LHCA2 LHCB5 LHCB5 PSBS PSBS TRXF1 TRXF1 OEP161 OEP161 RPP1 RPP1 RPP4 RPP4 CAO CAO T9J22.17 T9J22.17 RPS16-1 RPS16-1 CPN10-2 CPN10-2 T20K9.9 T20K9.9 CCH CCH THIC THIC LHCB1.3 LHCB1.3 RBCS-1B RBCS-1B RBCS-2B RBCS-2B RBCS-3B RBCS-3B TSB1 TSB1 PORB PORB CPN60B1 CPN60B1 FSD1 FSD1 PRK PRK GAPA1 GAPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACP2Acyl carrier protein 2, chloroplastic; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (136 aa)
LHCA4Chlorophyll a-b binding protein 4, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (251 aa)
TCTP1Translationally-controlled tumor protein 1; General regulator required for the development of the entire plant. Regulates the duration of cell cycle. Probable activator of Rab GTPases and upstream regulator of the cell growth- regulating TOR (target of rapamycin) network. Might also control spatial growth in pollen tubes or root hairs via the TORC2 signaling branch. Involved in the regulation of abscisic acid- and calcium-mediated stomatal closure, but not in light or H(+)-pumping induced stomatal opening. May regulate microtubules depolymerization. Binds calcium and has a cytoprotecti [...] (168 aa)
FFCSignal recognition particle 54 kDa protein, chloroplastic; Involved in cotranslational and post-translational sorting of thylakoid proteins. Binds GTP specifically. Activates the GTPase activity of CPFTSY when bound together. Required for light-harvesting chlorophyll a/b-binding protein (LHCP) integration into thylakoids. (564 aa)
DRT112Plastocyanin major isoform, chloroplastic; Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I. Seems to be the major plastocyanin in Arabidopsis. (167 aa)
FAD6Omega-6 fatty acid desaturase, chloroplastic; Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. (448 aa)
GSTF2Glutathione S-transferase F2; Binds auxin, endogenous flavonoids and the phytoalexin camalexin and may be involved in regulating the binding and transport of small bioactive natural products and defense-related compounds during plant stress. Binds a series of heterocyclic compounds, including lumichrome, harmane, norharmane and indole-3-aldehyde. In vitro, possesses glutathione S-transferase activity toward 1-chloro- 2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC). Acts as glutathione peroxidase on cumene hydroperoxide, linoleic acid-13- hydroperoxide and trans-stilbene oxid [...] (212 aa)
PSANPhotosystem I reaction center subunit N, chloroplastic; May function in mediating the binding of the antenna complexes to the PSI reaction center and core antenna. Plays an important role in docking plastocyanin to the PSI complex. Does not bind pigments. (171 aa)
LHCA1Chlorophyll a-b binding protein 6, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. (241 aa)
LHCB4.1Chlorophyll a-b binding protein CP29.1, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (290 aa)
THI1Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance. A [...] (349 aa)
FER1Ferritin-1, chloroplastic; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity). (255 aa)
Lhb1B2Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (265 aa)
Lhb1B1Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (266 aa)
VDE1Violaxanthin de-epoxidase, chloroplastic; Part of the xanthophyll (or violaxanthin) cycle for controlling the concentration of zeaxanthin in chloroplasts. Catalyzes the two-step mono de-epoxidation reaction. Stereospecific for all-trans xanthophylls. Zeaxanthin induces the dissipation of excitation energy in the chlorophyll of the light-harvesting protein complex of photosystem II; Belongs to the calycin superfamily. Lipocalin family. (462 aa)
PSBP1Oxygen-evolving enhancer protein 2-1, chloroplastic; May be involved in the regulation of photosystem II; Belongs to the psbP family. (263 aa)
F4L23.31Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein. (134 aa)
PDE334ATPase, F0 complex, subunit B/B', bacterial/chloroplast; Belongs to the ATPase B chain family. (219 aa)
RBL11Rhomboid-like protein 11, chloroplastic; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. May be involved in TIC22 processing during its import. Belongs to the peptidase S54 family. (280 aa)
T6D22.20Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
PGRL1APGR5-like protein 1A, chloroplastic; Ferredoxin-plastoquinone reductase involved in cyclic electron flow (CEF) around photosystem I. The homodimer is probably not involved in CEF; Belongs to the PGR5 family. (324 aa)
CYB561ATransmembrane ascorbate ferrireductase 1; Two-heme-containing cytochrome. Catalyzes ascorbate-dependent trans-membrane ferric-chelate reduction. Able to use dihydrolipoic acid (DHLA) as an alternative substrate to ascorbate. (239 aa)
ALB3Inner membrane protein ALBINO3, chloroplastic; Required for the insertion of some light harvesting chlorophyll-binding proteins (LHCP) into the chloroplast thylakoid membrane. Required for the insertion of LHCB1, LHCB4.1 and LHCB5 proteins into thylakoid membrane, while it is not required for insertion of proteins PsbX, PsbW and PsbY. (462 aa)
CURT1BProtein CURVATURE THYLAKOID 1B, chloroplastic; Determines thylakoid architecture by inducing membrane curvature. (174 aa)
T16L1.30Metallo-beta-lactamase family protein. (355 aa)
EMB3003Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (465 aa)
LFNR1Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic; Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power; Belongs to the ferredoxin--NADP reductase type 1 family. (360 aa)
T2K12.1Translation factor GUF1 homolog, chloroplastic; Promotes chloroplast protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. (681 aa)
LHCB6Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (258 aa)
T20L15.20Protein LURP-one-related 15; Might be related to the phospholipid scramblase and tubby- like superfamily of membrane tethered transcription factors. Belongs to the LOR family. (217 aa)
MSBP2Membrane steroid-binding protein 2; Belongs to the cytochrome b5 family. MAPR subfamily. (233 aa)
GPT1Glucose-6-phosphate/phosphate translocator 1, chloroplastic; Glucose 6-phosphate (Glc6P) transporter. Transports also inorganic phosphate, 3-phosphoglycerate, triose phosphates and, to a leser extent, phosphoenolpyruvate. Responsible for the transport of Glc6P into plastids of heterotrophic tissues where it can be used as a carbon source for starch biosynthesis, as substrate for fatty acid biosynthesis or as substrate for NADPH generation via the oxidative pentose phosphate pathway (OPPP). Required for pollen maturation and embryo sac development. (388 aa)
AIG2BProtein AIG2 B; Putative gamma-glutamylcyclotransferase. Belongs to the gamma-glutamylcyclotransferase family. (169 aa)
PSAE2Photosystem I reaction center subunit IV B, chloroplastic; Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase. (145 aa)
psaD1Photosystem I reaction center subunit II-1, chloroplastic; PsaD can form complexes with ferredoxin and ferredoxin- oxidoreductase in photosystem I (PS I) reaction center. PSAD may encode the ferredoxin-docking protein. (208 aa)
LHCB3Chlorophyll a-b binding protein 3, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Modulates the rate of photosystem II (PSII) state transitions and influences PSII macrostructure. Involved in PSII excitation energy transfer and charge separation during photosynthesis in thylakoids. (265 aa)
PSAE1Photosystem I reaction center subunit IV A, chloroplastic; Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase. (143 aa)
PSAD2Photosystem I reaction center subunit II-2, chloroplastic; PSAD can form complexes with ferredoxin and ferredoxin- oxidoreductase in photosystem I (PS I) reaction center. PSAD may encode the ferredoxin-docking protein (By similarity). (204 aa)
TRX-M4Thioredoxin M4, chloroplastic; Thiol-disulfide oxidoreductase involved in the redox regulation of enzyme of the oxidative pentose phosphate pathway. Under reducing conditions, inhibits the glucose-6-phosphate dehydrogenase. Belongs to the thioredoxin family. Plant M-type subfamily. (193 aa)
PSAFPhotosystem I reaction center subunit III, chloroplastic; Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI. (221 aa)
LHCB2.1Chlorophyll a-b binding protein 2.1, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (By similarity). Mediates rapid phosphorylation and migration of LHCII-PSII to photosystem I (PSI) after transition to state 2 (red) light conditions, thus leading to the formation of PSI-PSII-LHCII and PSI-LHCII supercomplex to balance the relative excitation of PSI and PSII. Involved in the production of reactive oxygen species (ROS) and stomatal closure upon abscisic acid ( [...] (265 aa)
PSBXPhotosystem II subunit X. (116 aa)
PSALPhotosystem I reaction center subunit XI, chloroplastic; Belongs to the PsaL family. (219 aa)
LHCA3Photosystem I chlorophyll a/b-binding protein 3-1, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated, here photosystem I. (273 aa)
F11M15.26Photosystem II 5 kD protein. (106 aa)
LHCA2Photosystem I chlorophyll a/b-binding protein 2, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated, here photosystem I. (257 aa)
LHCB5Chlorophyll a-b binding protein CP26, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (280 aa)
PSBSPhotosystem II 22 kDa protein, chloroplastic; Plays an important role in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. Is not necessary for efficient light harvesting and photosynthesis. Belongs to the ELIP/psbS family. (265 aa)
TRXF1Thioredoxin F1, chloroplastic; Thiol-disulfide oxidoreductase involved in the redox regulation of enzymes of both reductive pentose phosphate pathway (Calvin-Benson cycle) and oxidative pentose phosphate pathway. Under light or reducing conditions, activates in chloroplast the glyceraldehyde-3-phosphate dehydrogenase, the phosphoribulokinase and the fructose-1,6-bisphosphate phosphatase, and inhibits the glucose-6- phosphate dehydrogenase. (178 aa)
OEP161Outer envelope pore protein 16-1, chloroplastic; Voltage-dependent high-conductance channel with a slight cation-selectivity; selective for amino acids but excludes triosephosphates or uncharged sugars (By similarity). Non-essential amino acid-selective channel protein and translocation pore for NADPH:protochlorophyllide oxidoreductase A (PORA) and possibly PORB. Involved in PORA precursor (pPORA) import and thus confers photoprotection onto etiolated seedlings during greening. (148 aa)
RPP1Probable disease resistance protein RPP1; TIR-NB-LRR receptor-like protein that confers resistance to the pathogen Hyaloperonospora arabidopsis (By similarity). Probably acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death. (1194 aa)
RPP4Disease resistance protein RPP4; TIR-NB-LRR receptor-like protein that confers resistance to the pathogen Hyaloperonospora arabidopsis isolates Emoy2 and Emwa1 (downy mildew disease). Plays a role in the regulation of temperature response during plant growth and survival. (1147 aa)
CAOSignal recognition particle 43 kDa protein, chloroplastic; Component of the chloroplast signal recognition particle pathway. Required for post-translational targeting of proteins into the thylakoid membrane but seems to be dispensable for co-translational targeting with a translating ribosome present. May be able to function independently of cpFTSY and FFC/cpSRP54 in targeting LHCPs to the thylakoids. Acts as a highly specific chaperone for LHCPs, preventing aggregation and being able to dissolve aggregates. (373 aa)
T9J22.17Cytochrome b6f complex subunit (PetM). (125 aa)
RPS16-130S ribosomal protein S16-1, chloroplastic. (113 aa)
CPN10-210 kDa chaperonin 2, chloroplastic; Functions as co-chaperone for protein folding in chloroplasts. (139 aa)
T20K9.9VQ motif-containing protein. (114 aa)
CCHCopper transport protein CCH; Involved in copper homeostasis. Can complement the yeast mutants atx1 and sod1. (121 aa)
THICPhosphomethylpyrimidine synthase, chloroplastic; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (644 aa)
LHCB1.3Chlorophyll a-b binding protein 1, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (267 aa)
RBCS-1BRibulose bisphosphate carboxylase small chain 1B, chloroplastic; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity); Belongs to the RuBisCO small chain family. (181 aa)
RBCS-2BRibulose bisphosphate carboxylase small chain 2B, chloroplastic; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity); Belongs to the RuBisCO small chain family. (181 aa)
RBCS-3BRibulose bisphosphate carboxylase small chain 3B, chloroplastic; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity). (181 aa)
TSB1Tryptophan synthase beta chain 1, chloroplastic; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. (470 aa)
PORBProtochlorophyllide reductase B, chloroplastic; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide); Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily. (401 aa)
CPN60B1Chaperonin 60 subunit beta 1, chloroplastic; Binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer. Involved in protein assisted folding. Required for proper plastid division. (600 aa)
FSD1Superoxide dismutase [Fe] 1, chloroplastic; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (212 aa)
PRKPhosphoribulokinase, chloroplastic; Belongs to the phosphoribulokinase family. (395 aa)
GAPA1Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic; Involved in the photosynthetic reductive pentose phosphate pathway (Calvin-Benson cycle). Catalyzes the reduction of 1,3- diphosphoglycerate by NADPH (By similarity). (396 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.