STRINGSTRING
SPI SPI SFH1 SFH1 XI-K XI-K KIP KIP SAC7 SAC7 F26A9.21 F26A9.21 PI4KB1 PI4KB1 RABA4B RABA4B ANN1 ANN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPIProtein SPIRRIG; Involved in cell morphogenesis. May have a function in membrane fusion or membrane composition. Required for salt stress tolerance. Regulates the salt stress-dependent post-transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress- regulated mRNAs. (3601 aa)
SFH1Phosphatidylinositol/phosphatidylcholine transfer protein SFH1; Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Plays a role in root hair tip elongation as a key regulator of polarized membrane trafficking. May promote the PtdIns(4,5)P2 synthesis and organization in root hair membrane. Belongs to the SFH family. (554 aa)
XI-KMyosin-17; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells and in the elongation of trichome stalk and branches. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Acts as the primary co [...] (1531 aa)
KIPProtein KINKY POLLEN; May be involved in membrane trafficking (By similarity). Required for tip growth in pollen tubes and root hairs. Belongs to the SABRE family. (2587 aa)
SAC7Phosphoinositide phosphatase SAC7; Phosphoinositide phosphatase that preferentially hydrolyzes PtdIns(4)P. Regulates the accumulation of PtdIns(4)P on membrane compartments at the tips of growing root hairs leading to proper root hair development. (597 aa)
F26A9.21ARM repeat superfamily protein. (909 aa)
PI4KB1Phosphatidylinositol 4-kinase beta 1; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5- trisphosphate. Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB2, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB2 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway. (1121 aa)
RABA4BRas-related protein RABA4b; Regulator of membrane trafficking. May be required for secretion of cell wall components in cells; Belongs to the small GTPase superfamily. Rab family. (224 aa)
ANN1Annexin D1; Has a peroxidase activity. May act in counteracting oxidative stress. May also mediate regulated, targeted secretion of Golgi-derived vesicles during seedling development. (317 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.