STRINGSTRING
A0A1I9LNY7 A0A1I9LNY7 A0A1P8BGX5 A0A1P8BGX5 SPT6 SPT6 A8MSB8_ARATH A8MSB8_ARATH NEDD1 NEDD1 ARPC5B ARPC5B XLG2 XLG2 F20D21.5 F20D21.5 XI-E XI-E XI-C XI-C NET1D NET1D T6H22.14 T6H22.14 XI-B XI-B VIII-A VIII-A XI-A XI-A ILA ILA F8D11.8 F8D11.8 LETM2 LETM2 BOP1 BOP1 F14M4.8 F14M4.8 XI-F XI-F T32F6.13 T32F6.13 XI-G XI-G XI-D XI-D ARPC2B ARPC2B F4J2T9_ARATH F4J2T9_ARATH F4J6A8_ARATH F4J6A8_ARATH LETM1 LETM1 MGH6.2 MGH6.2 PA200 PA200 F4C21.30 F4C21.30 NET1B NET1B VIII-B VIII-B XI-H XI-H GTC2 GTC2 ARPC4 ARPC4 CHR17 CHR17 VIII-2 VIII-2 EML3 EML3 GEX2 GEX2 XI-K XI-K CDC20-6 CDC20-6 T21H19.10 T21H19.10 MYH19.120 MYH19.120 WLIN2A WLIN2A PHB3 PHB3 FH8 FH8 EIF6-1 EIF6-1 FH2 FH2 RPP1B RPP1B FH3 FH3 RACK1A RACK1A FH4 FH4 RPN13 RPN13 ADF9 ADF9 FIM2 FIM2 VPS28-1 VPS28-1 VLN4 VLN4 T4L20.310 T4L20.310 XLG1 XLG1 MRF2 MRF2 F13P17.9 F13P17.9 PLIM2A PLIM2A CPFTSY CPFTSY ARPC1A ARPC1A TOC159 TOC159 VLN1 VLN1 VLN2 VLN2 VLN3 VLN3 IF3-2 IF3-2 SPT16 SPT16 F2P3.7 F2P3.7 CPA-2 CPA-2 ERG ERG NET2A NET2A VHA-B1 VHA-B1 GPA1 GPA1 F4H5.15 F4H5.15 T06B20.3 T06B20.3 His1-3 His1-3 SSRP1 SSRP1 XI-I XI-I T16K5.80-2 T16K5.80-2 PLIM2B PLIM2B NUCL2 NUCL2 F20D21.6 F20D21.6 XI-1 XI-1 ADF1 ADF1 ADF2 ADF2 CDC20-5 CDC20-5 HMGA HMGA CDC20-4 CDC20-4 HON5 HON5 PLIM2C PLIM2C PIP5K1 PIP5K1 ADF8 ADF8 SCAR4 SCAR4 SCAR2 SCAR2 WAVE5 WAVE5 T1N15.15 T1N15.15 ADF7 ADF7 T3K9.21 T3K9.21 Q6AWW7_ARATH Q6AWW7_ARATH SCAR1 SCAR1 IF3-1 IF3-1 F28J7.13 F28J7.13 FIM1 FIM1 RAD23D RAD23D RAD23C RAD23C RAD23A RAD23A RAD23B RAD23B UBP7 UBP7 FH9 FH9 Q8GXC9_ARATH Q8GXC9_ARATH FZR2 FZR2 RPP1A RPP1A RPP1C RPP1C ADF12 ADF12 ARP6 ARP6 ARPC2A ARPC2A ABCE2 ABCE2 FZR3 FZR3 F28N24.2 F28N24.2 CHR11 CHR11 NUF2 NUF2 TIG TIG K1F13.13 K1F13.13 FZR1 FZR1 VHA-B3 VHA-B3 MRF3 MRF3 MAJ23.90 MAJ23.90 ELF5A-2 ELF5A-2 Q945Q5_ARATH Q945Q5_ARATH F1N13.50 F1N13.50 UBP6 UBP6 IF3-4 IF3-4 FH5 FH5 MRF1 MRF1 WLIM1 WLIM1 BRK1 BRK1 T31K7.7 T31K7.7 MAMYB MAMYB LOS1 LOS1 RACK1B RACK1B ELF5A-3 ELF5A-3 XLG3 XLG3 SAMBA SAMBA T15M6.8 T15M6.8 FH14 FH14 F26A9.19 F26A9.19 ANN5 ANN5 F12B7.17 F12B7.17 F16M19.22 F16M19.22 T18K17.15 T18K17.15 EIF2A EIF2A MCK7.28 MCK7.28 K22G18.11 K22G18.11 K11I1.1 K11I1.1 KIN14E KIN14E SWC6 SWC6 FIM3 FIM3 MTI20.22 MTI20.22 FH6 FH6 FIM5 FIM5 MYH19.60 MYH19.60 K18P6.3 K18P6.3 RICE2 RICE2 T2K12.1 T2K12.1 TOR TOR NUCL1 NUCL1 F3C3.2 F3C3.2 IJ IJ WDR12 WDR12 VIII-1 VIII-1 K16F4.7 K16F4.7 ABCE1 ABCE1 XI-2 XI-2 SCAR3 SCAR3 ADF10 ADF10 HON4 HON4 RPN11 RPN11 emb1441 emb1441 NET1A NET1A RACK1C RACK1C AIP1-2 AIP1-2 VLN5 VLN5 PES PES CP12-2 CP12-2 ADF11 ADF11 WLIM2B WLIM2B EIF6-2 EIF6-2 F17I23.60 F17I23.60 ABCE3 ABCE3 C17L7.230 C17L7.230 C17L7.190 C17L7.190 C17L7.180 C17L7.180 C17L7.170 C17L7.170 C17L7.160 C17L7.160 C17L7.150 C17L7.150 ARPC5A ARPC5A T17J13.200 T17J13.200 RRF RRF XI-J XI-J T21J18.150 T21J18.150 F5K20_270 F5K20_270 CPB CPB FH11 FH11 CDC20-3 CDC20-3 CDC20-2 CDC20-2 VPS28-2 VPS28-2 YchF1 YchF1 FH1 FH1 RICE1 RICE1 STIPL1 STIPL1 NMD3 NMD3 IF2AH_ARATH IF2AH_ARATH FIM4 FIM4 LSG1-2 LSG1-2 ARPC1B ARPC1B F11A3.9 F11A3.9 BSD2 BSD2 LPE1 LPE1 FH10 FH10 CDC48C CDC48C MRF4 MRF4 RAP74 RAP74 PI4KA1 PI4KA1 TIF3K1 TIF3K1 CDC20-1 CDC20-1 PETs PETs ELF5A-1 ELF5A-1 FH7 FH7 MEE14 MEE14 OTU6 OTU6 ADF5 ADF5 NET1C NET1C F4C21.32 F4C21.32 7SL2 7SL2 ADF6 ADF6 ADF4 ADF4 ADF3 ADF3 7SL1 7SL1 AIP1-1 AIP1-1 F9K20.24 F9K20.24
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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A0A1I9LNY7Formin-like protein. (160 aa)
A0A1P8BGX5JAB1/Mov34/MPN/PAD-1 ubiquitin protease. (122 aa)
SPT6Transcription elongation factor SPT6 homolog; Transcription elongation factor that enhances the transcription elongation by RNA polymerase II (RNAPII) (By similarity). Plays an important role in regulating embryo apical and basal patterning during early embryogenesis, partly through negative regulation of the transcription factors PHABULOSA and PHAVOLUTA. Belongs to the SPT6 family. (1647 aa)
A8MSB8_ARATHTransmembrane protein, putative (DUF3317). (56 aa)
NEDD1Protein NEDD1; Regulates microtubules organization in a centrosome- independent manner. Required for the spindle to be positioned correctly and for the function of gamma-tubulin in organizing phragmoplast microtubules. Component of active gamma-tubulin ring complexes (gamma-TuRCs) associated with cortical microtubules in interphase cells. Mediates gamma-TuRC recruitment to the nucleation sites and is important for determining the ratio of branched to parallel nucleation. May mediate the localization of GCP2 and GCP3 to the nuclear envelope. (782 aa)
ARPC5BActin-related protein 2/3 complex subunit 5B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (135 aa)
XLG2Extra-large guanine nucleotide-binding protein 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (By similarity). Binds GTP with specificity. Plays a role in the root morphogenesis by regulation of the cell proliferation. Acts as a positive regulator in resistance to pathogen that triggers the salicylic acid (SA) pathway. Promotes the DNA binding activity of RTV1 specifically to promoter regions of FT and SOC1 in vivo leading to the activation of floral integrator genes. Belongs to the G-alpha family [...] (861 aa)
F20D21.5Winged helix-turn-helix transcription repressor DNA-binding protein. (232 aa)
XI-EMyosin-11; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks, mitochondria and peroxisomes. (1529 aa)
XI-CMyosin-9; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1538 aa)
NET1DProtein NETWORKED 1D; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (1733 aa)
T6H22.14Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (421 aa)
XI-BMyosin-8; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1500 aa)
VIII-AMyosin-3; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1153 aa)
XI-AMyosin-7; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1730 aa)
ILAProtein ILITYHIA; Involved in immunity against bacterial infection and in non- host resistance. Required for embryo development. Required for systemic acquired resistance, but functions in an salicylic acid-independent manner. Required for bacterium-triggered stomatal closure response ; Belongs to the GCN1 family. (2696 aa)
F8D11.8P-loop containing nucleoside triphosphate hydrolases superfamily protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (170 aa)
LETM2LETM1-like protein. (736 aa)
BOP1Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (By similarity). Plays an essential role in cell growth and survival through its regulation of ribosome biogenesis and mitotic progression ; Belongs to the WD repeat BOP1/ERB1 family. (753 aa)
F14M4.8Zinc ion binding/nucleic acid binding protein. (766 aa)
XI-FMyosin-12; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1556 aa)
T32F6.13Ubiquitin-like superfamily protein. (242 aa)
XI-GMyosin-13; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1493 aa)
XI-DMyosin-10; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1770 aa)
ARPC2BActin-related protein 2/3 complex subunit 2B; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development (By similarity). (374 aa)
F4J2T9_ARATHRibosomal protein S5/Elongation factor G/III/V family protein. (1015 aa)
F4J6A8_ARATHDnaJ and Myb-like DNA-binding domain-containing protein. (647 aa)
LETM1LETM1-like protein. (760 aa)
MGH6.2Ribosomal protein S5/Elongation factor G/III/V family protein. (820 aa)
PA200Proteasome activator subunit 4; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin- independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA d [...] (1811 aa)
F4C21.30Ubiquitin family protein. (322 aa)
NET1BProtein NETWORKED 1B; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (1710 aa)
VIII-BMyosin-4; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). (1134 aa)
XI-HMyosin-14; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1516 aa)
GTC2GTC2. (343 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (169 aa)
CHR17ISWI chromatin-remodeling complex ATPase CHR17; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Necessar [...] (1069 aa)
VIII-2Myosin-2; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). Involved in endocytosis via its action in endosomal trafficking; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class VIII subfamily. (1220 aa)
EML3Protein EMSY-LIKE 3; Probably involved in the regulation of chromatin states (Probable). Contributes to basal immunity. (397 aa)
GEX2Protein GAMETE EXPRESSED 2. (914 aa)
XI-KMyosin-17; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells and in the elongation of trichome stalk and branches. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Acts as the primary co [...] (1531 aa)
CDC20-6Cell division cycle 20.6, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (428 aa)
T21H19.10RAD23 UV excision repair family protein. (171 aa)
MYH19.120GTP-binding protein. (621 aa)
WLIN2ALIM domain-containing protein WLIM2a; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]. (200 aa)
PHB3Prohibitin-3, mitochondrial; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins (By similarity). Necessary for mitochondrial and cell metabolism and biogenesis. Required to regulate the ethylene-mediated signaling; involved in growth maintenance in the presence of ethylene. Functions in nitric oxide (NO)-mediated responses and in hydrogen peroxide- induced NO accumulation. (277 aa)
FH8Formin-like protein 8; Might be involved in the organization and polarity of the actin cytoskeleton. Interacts with the barbed end of actin filaments and nucleates actin-filament polymerization in vitro. (760 aa)
EIF6-1Eukaryotic translation initiation factor 6-1; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. Belongs to the eIF-6 family. (247 aa)
FH2Formin-like protein 2; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (894 aa)
RPP1B60S acidic ribosomal protein P1-2; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
FH3Formin-like protein 3; Acts as actin nucleation factor that directs the formation of actin cables and polarized growth in pollen tubes. (785 aa)
RACK1AReceptor for activated C kinase 1A; Major component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes. MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway. Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. (327 aa)
FH4Formin-like protein 4; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (763 aa)
RPN1326S proteasome regulatory subunit RPN13; Functions as a proteasomal ubiquitin receptor. Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-63'-linked ubiquitin chains. (300 aa)
ADF9Actin-depolymerizing factor 9; Does not display typical F-actin depolymerizing activity. Exhibits a high ability to stabilize and cross-link actin filaments. Functions as an actin bundling protein with the highest efficiency under acidic conditions. May play a role in the modulation of levels of histone H3 lysine 4 trimethylation and H3 lysine 9 and 14 acetylation at the FLC locus. Belongs to the actin-binding proteins ADF family. (141 aa)
FIM2Fimbrin-2; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (654 aa)
VPS28-1Vacuolar protein sorting-associated protein 28 homolog 1; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity); Belongs to the VPS28 family. (209 aa)
VLN4Villin-4; Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Involved in root hair growth through regulating actin organization in a Ca(2+)-dependent manner. (974 aa)
T4L20.310Probable ribosome-binding factor A, chloroplastic. (215 aa)
XLG1Extra-large guanine nucleotide-binding protein 1; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (By similarity). Binds GTP with specificity. Plays a role in the root morphogenesis by regulation of the cell proliferation. (888 aa)
MRF2MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 2; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Belongs to the PDCD4 family. (693 aa)
F13P17.9SecY protein transport family protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
PLIM2ALIM domain-containing protein PLIM2a; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are inhibited by pH > 6.8 but are [Ca(2+)] independent. (226 aa)
CPFTSYCell division protein FtsY homolog, chloroplastic; Signal recognition particle receptor protein. Binds GTP specifically. The GTPase activity is inhibited by the N-terminus of the protein until binding to the thylakoid membrane. Activates the GTPase activity of FFC/cpSRP54 when bound to the cpSRP complex. Required for light-harvesting chlorophyll a/b-binding protein (LHCP) integration into thylakoids. Might be also functionally linked to the Sec translocation machinery. (366 aa)
ARPC1AActin-related protein 2/3 complex subunit 1A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (378 aa)
TOC159Translocase of chloroplast 159, chloroplastic; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Required for chloroplast biogenesis. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily. (1503 aa)
VLN1Villin-1; Binds actin and actin filament bundles in a Ca(2+)/calmodulin-insensitive manner, but is unable to sever, cap, and nucleate actin filament formation in vitro. Does not protect individual filaments from severing by VLN3 (AC O81645). Belongs to the villin/gelsolin family. (909 aa)
VLN2Villin-2; Ca(2+)-regulated actin-binding protein. Involved in actin filaments bundling. Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Required for the construction of actin collars in pollen tubes. Acts redundantly with VLN5 (AC Q9LVC6) to generate thick actin filament bundles and to regulate polarized pollen tube growth. Acts redundantly with VLN3 (AC O81645) to regulate directional organ growth and in sclerenchyma development (respectively). Belongs to the villin/gelsolin family. (976 aa)
VLN3Villin-3; Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but severs actin filaments in a calcium-dependent manner, regardless of the presence or not of VLN1 (AC O81643). Acts redundantly with VLN2 (AC O81644) to generate thick actin filament bundles, to regulate directional organ growth and in sclerenchyma development. (965 aa)
IF3-2Translation initiation factor IF3-2, chloroplastic; Chloroplast translation initiation factor that is essential for the coordination of leaf and chloroplast development. IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity). (312 aa)
SPT16FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1074 aa)
F2P3.7Translation initiation factor IF-1, chloroplastic; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (141 aa)
CPA-2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (308 aa)
ERGGTP-binding protein ERG; Has a crucial role in plant growth and development, possibly by influencing mitochondrial division. (437 aa)
NET2AProtein NETWORKED 2A; Plant-specific actin binding protein. Associates with F-actin at the plasma membrane in growing pollen tubes. May be part of a membrane-cytoskeletal adapter complex; Belongs to the NET family. (947 aa)
VHA-B1V-type proton ATPase subunit B1; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (486 aa)
GPA1Guanine nucleotide-binding protein alpha-1 subunit; Exhibits a fast rate of basal nucleotide exchange. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Together with GCR1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate (IP(3)) as a second messenger. Promotes abscisic acid (ABA) responses in guard cells. But, together with GCR1 and GB1, acts as a negative regulator of ABA during seed ge [...] (383 aa)
F4H5.15Histone H1.1; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (274 aa)
T06B20.3Histone H1.2; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (273 aa)
His1-3Putative histone H1 protein. (167 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (646 aa)
XI-IMyosin-15; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria. Plays a role in nuclear shape determination. Drives nuclear movement along actin filaments. As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasm [...] (1522 aa)
T16K5.80-2GTP-binding protein At3g49725, chloroplastic. (620 aa)
PLIM2BLIM domain-containing protein PLIM2b; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are inhibited by pH > 6.8 but are [Ca(2+)] independent. (205 aa)
NUCL2Nucleolin 2; Involved in pre-rRNA processing and ribosome assembly. (636 aa)
F20D21.6Winged-helix DNA-binding transcription factor family protein. (229 aa)
XI-1Myosin-5; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Contributes to the trafficking of Golgi stacks, mitochondria and peroxisomes. Required for development of pavement cells, trichomes, and stigmatic papillae. (1520 aa)
ADF1Actin-depolymerizing factor 1; Actin-depolymerizing protein. Stimulates F-actin depolymerization. Involved in plant development, cell organ expansion and flowering by controlling breakdown of thick actin cables. Severs actin filaments or bundles and promotes actin cytoskeleton disassembly. Binds monomeric actin (G- actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. (139 aa)
ADF2Actin-depolymerizing factor 2; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Required for normal cell growth, plant development, cell organ expansion and flowering. Essential for root-knot nematode infection. (137 aa)
CDC20-5Cell division cycle 20.5, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (450 aa)
HMGAHMG-Y-related protein A; Binds A/T-rich DNA with a highly dynamic distribution into the nucleus. (204 aa)
CDC20-4Cell division cycle 20.4, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (444 aa)
HON5High mobility group A5. (479 aa)
PLIM2CLIM domain-containing protein PLIM2c; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. Associates predominantly with long and dynamic actin bundles in the shank of growing pollen tubes. The actin regulatory activities are inhibited by pH > 6.8 and/or high [Ca(2+)]. (213 aa)
PIP5K1Phosphatidylinositol 4-phosphate 5-kinase 1; Catalyzes the synthesis of phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4-bisphosphate. (752 aa)
ADF8Actin-depolymerizing factor 8; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (140 aa)
SCAR4Protein SCAR4; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (1170 aa)
SCAR2Protein SCAR2; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. Belongs to the SCAR/WAVE family. (1399 aa)
WAVE5Scar-like domain-containing protein WAVE 5. (2028 aa)
T1N15.15Proteasome inhibitor-like protein. (175 aa)
ADF7Actin-depolymerizing factor 7; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Required for pollen tube growth. Promotes turnover of longitudinal actin cables by severing actin filaments in pollen tubes. (137 aa)
T3K9.21WW domain-containing protein. (463 aa)
Q6AWW7_ARATHWinged-helix DNA-binding transcription factor family protein. (457 aa)
SCAR1Protein SCAR1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (821 aa)
IF3-1Translation initiation factor IF3-1, mitochondrial; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (520 aa)
F28J7.13Putative ribosome recycling factor. (267 aa)
FIM1Fimbrin-1; Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin aggregates. Stabilizes and prevents F-actin depolymerization mediated by profilin. Key regulator of actin cytoarchitecture, probably involved in cell cycle, cell division, cell elongation and cytoplasmic tractus. (687 aa)
RAD23DUbiquitin receptor RAD23d; May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP) (By similarity); Belongs to the RAD23 family. (378 aa)
RAD23CUbiquitin receptor RAD23c; May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). (419 aa)
RAD23AProbable ubiquitin receptor RAD23a; May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP) (By similarity); Belongs to the RAD23 family. (368 aa)
RAD23BUbiquitin receptor RAD23b; May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP); Belongs to the RAD23 family. (371 aa)
UBP7Ubiquitin carboxyl-terminal hydrolase 7; Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). (477 aa)
FH9Formin-like protein 9; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (782 aa)
Q8GXC9_ARATHActin cross-linking protein, putative (DUF569). (335 aa)
FZR2Protein FIZZY-RELATED 2; Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Necessary and sufficient for endoreduplication and correct cell expansion. Controls meristem size by stimulating endoreduplication in the elongation zone. (483 aa)
RPP1A60S acidic ribosomal protein P1-1; Plays an important role in the elongation step of protein synthesis. (112 aa)
RPP1C60S acidic ribosomal protein P1-3; Plays an important role in the elongation step of protein synthesis. (113 aa)
ADF12Actin-depolymerizing factor 12; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (137 aa)
ARP6Actin-related protein 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Binds to the promoter region of FLC chromatin. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. [...] (421 aa)
ARPC2AActin-related protein 2/3 complex subunit 2A; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the ARPC2 family. (318 aa)
ABCE2ABC transporter E family member 2. (605 aa)
FZR3Protein FIZZY-RELATED 3; Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C); Belongs to the WD repeat CDC20/Fizzy family. (481 aa)
F28N24.2SecY protein transport family protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
CHR11ISWI chromatin-remodeling complex ATPase CHR11; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Involved in nuclear proliferation during megagametogenesis and cell expansion in the sporophyte. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key [...] (1056 aa)
NUF2Kinetochore protein NUF2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity to ensure proper cell division. Belongs to the NUF2 family. (440 aa)
TIGTrigger factor-like protein TIG, Chloroplastic; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Belongs to the FKBP-type PPIase family. Tig subfamily. (547 aa)
K1F13.13GTPase ERA-like, chloroplastic; Nuclear genome-encoded probable GTPase involved in ribosome biogenesis in chloroplasts. Plays a role in 16S rRNA maturation in plastids and may contribute to the assembly of the small (30S) ribosomal subunit. (427 aa)
FZR1Protein FIZZY-RELATED 1; Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for meristem organization and maintenance of quiescent center identity and stem cells. Belongs to the WD repeat CDC20/Fizzy family. (475 aa)
VHA-B3V-type proton ATPase subunit B3; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (487 aa)
MRF3MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 3; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Involved in the regulation of the ethylene-mediated signaling pathway. Involved in salt stress responses. Reduced cotyledons size and early flowering. (702 aa)
MAJ23.90NAD(P)-binding Rossmann-fold superfamily protein. (287 aa)
ELF5A-2Eukaryotic translation initiation factor 5A-2; The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Regulates cytokinin-mediated root protoxylem specification and represses secifically the expression of AHP6. Regulates the induction of programmed cell death caused by infection with virulent pathogen. (159 aa)
Q945Q5_ARATHBacterial trigger factor. (199 aa)
F1N13.50NAD(P)-binding Rossmann-fold superfamily protein. (269 aa)
UBP6Ubiquitin carboxyl-terminal hydrolase 6; Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins; Belongs to the peptidase C19 family. (482 aa)
IF3-4Translation initiation factor IF3-4, chloroplastic; Chloroplast translation initiation factor that is essential for the coordination of leaf and chloroplast development. IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity). (281 aa)
FH5Formin-like protein 5; Might be involved in the organization and polarity of the actin cytoskeleton. Interacts with the barbed end of actin filaments and nucleates actin-filament polymerization in vitro. Seems to play a role in cytokinesis. (900 aa)
MRF1MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 1; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. (702 aa)
WLIM1LIM domain-containing protein WLIM1; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]. (190 aa)
BRK1Protein BRICK 1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. (85 aa)
T31K7.730S ribosomal protein. (308 aa)
MAMYBTranscription factor MAMYB; Transcription factor involved in the regulation of root hair development, possibly through auxin signaling. Its endoplasmic reticulum membrane localization is not compatible with its transcription factor activity in the nucleus. May be cleaved to target the nucleus. (309 aa)
LOS1Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity). Involved in cold responses leading to freezing tolerance via the induction of cold- responsive genes. Belongs to the [...] (843 aa)
RACK1BReceptor for activated C kinase 1B; Minor component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes. MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway. Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. (326 aa)
ELF5A-3Eukaryotic translation initiation factor 5A-3; The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Involved in supporting growth and plays a regulatory role in the response to sub-lethal osmotic and nutrient stress. (158 aa)
XLG3Extra-large guanine nucleotide-binding protein 3; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (By similarity). Binds GTP with specificity. Plays a role in the root morphogenesis by regulation of the cell proliferation. Acts with GB1 in the positive regulation of root waving and root skewing; Belongs to the G-alpha family. XLG subfamily. (848 aa)
SAMBAProtein SAMBA; Plays an important role in organ size control. Acts as negative regulator of the anaphase-promoting complex/cyclosome (APC/C). Regulates cell proliferation during early development by targeting CYCA2-3 for APC/C-mediated degradation. Required for mitosis I during pollen microspore development. (100 aa)
T15M6.8WEB family protein. (284 aa)
FH14Formin-like protein 14; Belongs to the formin-like family. Class-II subfamily. (1230 aa)
F26A9.19At1g71430. (164 aa)
ANN5Annexin D5. (316 aa)
F12B7.17Protein Iojap-related, mitochondrial; May be a ribosome silencing factor involved in organelle biogenesis and required for germination; Belongs to the Iojap/RsfS family. (184 aa)
F16M19.22Transcription elongation factor SPT6-like; Transcription elongation factor that enhances the transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1322 aa)
T18K17.15Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (513 aa)
EIF2AEukaryotic translation initiation factor 2 subunit alpha; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction cataly [...] (344 aa)
MCK7.28E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family. (1873 aa)
K22G18.11Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (605 aa)
K11I1.116S rRNA processing protein RimM family. (653 aa)
KIN14EKinesin-like protein KIN-14E; Minus-end microtubule-dependent motor protein involved in the regulation of cell division and trichome morphogenesis through microtubules bundling. Possesses basal and microtubule-stimulated ATPase activities. Acts as a hub that brings together microtubules and actin filaments to modulate the cytoskeleton during trichome formation and morphogenesis. Could be involved in the negative regulation of root growth. (1260 aa)
SWC6SWR1 complex subunit 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Coodinates SWR1-C, FRI-C (FLC transcription activator complex), histone methyltransferase and general transcription factors. Represses flowering by positively regulating FLC and MAF4. Binds to the promoter region of FLC chromatin. (171 aa)
FIM3Fimbrin-3; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (714 aa)
MTI20.22GTP-binding protein, HflX. (540 aa)
FH6Formin-like protein 6; Might be involved in the organization and polarity of the actin cytoskeleton. (899 aa)
FIM5Fimbrin-5; Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin bundles. Stabilizes and prevents F-actin depolymerization mediated by latrunculin B (LatB). (687 aa)
MYH19.60Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily. (663 aa)
K18P6.3Putative 60S acidic ribosomal protein P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (111 aa)
RICE2Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2; 3'-to-5' exoribonuclease (RNase) specifically targeting single-stranded RNAs. Triggers miRNA accumulation in RNA-induced silencing complex (RISC), composed of miRNAs and AGO proteins, by degrading uridylated cleavage fragments. Required during plant growth and development (By similarity). Belongs to the RICE family. (206 aa)
T2K12.1Translation factor GUF1 homolog, chloroplastic; Promotes chloroplast protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. (681 aa)
TORSerine/threonine-protein kinase TOR; Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival. Involved in modulating the transition from heterotrophic [...] (2481 aa)
NUCL1Nucleolin 1; Involved in pre-rRNA processing and ribosome assembly. Is associated with intranucleolar chromatin and pre-ribosomal particles and plays a role in controlling activation and repression of a specific subset of rRNA genes located in distinctive nucleolar organizer regions. Binds specifically rDNA chromatin and may be required to maintain rDNA chromatin structure, but is probably not required for the overall histone methylation status of 45S rRNA genes. Involved in leaf polarity establishment by functioning cooperatively with AS1 to repress abaxial genes ARF3, ARF4, KAN1, KAN [...] (557 aa)
F3C3.2Uncharacterized protein At1g32220, chloroplastic. (296 aa)
IJProtein Iojap, chloroplastic; May be a ribosome silencing factor (Potential). Involved in plastid biogenesis (By similarity). (238 aa)
WDR12Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit. (433 aa)
VIII-1Myosin-1; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity). Involved in endocytosis via its action in endosomal trafficking. (1166 aa)
K16F4.7DnaJ and myb-like DNA-binding domain-containing protein. (663 aa)
ABCE1ABC transporter E family member 1; Belongs to the ABC transporter superfamily. ABCE family. (603 aa)
XI-2Myosin-6; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Targets the peroxisome through an interaction with RABC2A. Required for deve [...] (1505 aa)
SCAR3Protein SCAR3; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion. (1020 aa)
ADF10Actin-depolymerizing factor 10; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (140 aa)
HON4Winged-helix DNA-binding transcription factor family protein. (480 aa)
RPN1126S proteasome non-ATPase regulatory subunit 14 homolog; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily. (308 aa)
emb1441Zinc knuckle (CCHC-type) family protein. (1080 aa)
NET1AProtein NETWORKED 1A; Plant-specific actin binding protein. Associates with F-actin at the plasma membrane and plasmodesmata. May be part of a membrane- cytoskeletal adapter complex; Belongs to the NET family. (1728 aa)
RACK1CReceptor for activated C kinase 1C; Minor component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes. MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway. Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. (326 aa)
AIP1-2Actin-interacting protein 1-2; Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins. (609 aa)
VLN5Villin-5; Major actin filament stabilizing factor and regulator of actin dynamics. Binds actin and actin filament bundles in a Ca(2+)- insensitive manner, but caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. Required for the construction of actin collars in pollen tubes. Acts synergistically with VLN2 (AC O81644) to regulate polarized pollen tube growth. Belongs to the villin/gelsolin family. (962 aa)
PESPescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (By similarity). Plays an essential role in cell growth and survival through its regulation of ribosome biogenesis and mitotic progression. Required for normal root cell growth and differentiation. (590 aa)
CP12-2Calvin cycle protein CP12-2, chloroplastic; Acts as a linker essential in the assembly of a core complex of PRK/GAPDH. Coordinates the reversible inactivation of chloroplast enzymes GAPDH and PRK during darkness in photosynthetic tissues. Belongs to the CP12 family. (131 aa)
ADF11Putative actin-depolymerizing factor 11; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers; Belongs to the actin-binding proteins ADF family. (133 aa)
WLIM2BLIM domain-containing protein WLIM2b; Binds to actin filaments and promotes cross-linking into thick bundles. Has an actin-stabilizing activity. The actin regulatory activities are not regulated by pH and [Ca(2+)]. (199 aa)
EIF6-2Eukaryotic translation initiation factor 6-2; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. Belongs to the eIF-6 family. (245 aa)
F17I23.60Signal recognition particle receptor alpha subunit family protein. (634 aa)
ABCE3ABC transporter E family member 3. (181 aa)
C17L7.230Ubiquitin-like superfamily protein. (415 aa)
C17L7.190Ubiquitin-like superfamily protein. (129 aa)
C17L7.180Ubiquitin-like superfamily protein. (259 aa)
C17L7.170Ubiquitin-like superfamily protein. (318 aa)
C17L7.160Ubiquitin-like superfamily protein. (197 aa)
C17L7.150Ubiquitin-like superfamily protein. (206 aa)
ARPC5AActin-related protein 2/3 complex subunit 5A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (132 aa)
T17J13.200RING/U-box superfamily protein. (812 aa)
RRFRibosome-recycling factor, chloroplastic; Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis. Belongs to the RRF family. (275 aa)
XI-JMyosin-16; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily. (1242 aa)
T21J18.150F-box/LRR-repeat protein At3g48880. (309 aa)
F5K20_270Probable proteasome inhibitor; Could play an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome (By similarity); Belongs to the proteasome inhibitor PI31 family. (302 aa)
CPBProbable F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (256 aa)
FH11Formin-like protein 11; Might be involved in the organization and polarity of the actin cytoskeleton; Belongs to the formin-like family. Class-I subfamily. (884 aa)
CDC20-3Cell division cycle 20.3, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (442 aa)
CDC20-2Cell division cycle 20.2, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (447 aa)
VPS28-2Vacuolar protein sorting-associated protein 28 homolog 2; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity); Belongs to the VPS28 family. (210 aa)
YchF1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (Potential). Exhibits GTPase activity (By similarity). Confers sensitivity to salinity stress by suppressing the anti-oxidation enzymatic activities and increasing lipid peroxidation thus leading to the accumulation of reactive oxygen species (ROS). Acts as negative regulator of disease resistance against bacterial pathogen. (394 aa)
FH1Formin-like protein 1; Might be involved in the organization and polarity of the actin cytoskeleton. Involved in polar pollen cell growth process by maintaining tip-focused cell membrane expansion for the polar extension of pollen tubes; Belongs to the formin-like family. Class-I subfamily. (1051 aa)
RICE1Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 1; 3'-to-5' exoribonuclease (RNase) specifically targeting single-stranded RNAs. Triggers miRNA accumulation in RNA-induced silencing complex (RISC), composed of miRNAs and AGO proteins, by degrading uridylated cleavage fragments. Required during plant growth and development. Belongs to the RICE family. (200 aa)
STIPL1Septin and tuftelin-interacting protein 1 homolog 1; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events (By similarity). Involved in snRNPs recycling. Required for efficient splicing of genes that act within the plant circadian clock. Part of a transcription elongation checkpoint at alternative exons. Required for correct expression and splicing of DOG1, a regulator of seed dormancy. May induce transient transcriptional pausing of polymerase II at slices sites. (849 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (516 aa)
IF2AH_ARATHEukaryotic translation initiation factor 2 subunit alpha homolog; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reactio [...] (344 aa)
FIM4Fimbrin-4; Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus. (652 aa)
LSG1-2GTPase LSG1-2; GTPase involved in ribosome biogenesis (Probable). Binds to 23S rRNA and associates with 60S pre-ribosomes. Involved in early cotyledon and leaf development. Belongs to the TRAFAC class YlqF/YawG GTPase family. (589 aa)
ARPC1BActin-related protein 2/3 complex subunit 1B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the WD repeat ARPC1 family. (378 aa)
F11A3.9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (402 aa)
BSD2Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic; Chloroplast chaperone required for RuBisCo biogenesis and translational regulation of the RuBisCo large subunit (RbcL). Stabilizes an end-state assembly intermediate of eight RbcL subunits until the small subunits (RBCSs) become available to produce a complete stable RuBisCo complex containing eight small and eight large subunits. (136 aa)
LPE1Protein LOW PHOTOSYNTHETIC EFFICIENCY 1, chloroplastic; Required for light-regulated photosystem II (PSII) biogenesis and grana thylakoids formation by binding to the 5' UTR of PSII subunit mRNAs (e.g. psbJ, psbN and psbA) in a light-dependent manner through a redox-based mechanism, and facilitating the association of HCF173 with target mRNAs, which encodes PSII reaction center proteins (e.g. J, N and D1), thus regulating its expression by modulating ribosome loading. Belongs to the PPR family. P subfamily. (665 aa)
FH10Formin-like protein 10; Might be involved in the organization and polarity of the actin cytoskeleton. (841 aa)
CDC48CCell division control protein 48 homolog C; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity); Belongs to the AAA ATPase family. (820 aa)
MRF4MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 4; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Belongs to the PDCD4 family. (633 aa)
RAP74Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. (649 aa)
PI4KA1Phosphatidylinositol 4-kinase alpha 1; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate. Can bind to phosphatidylinositol 4-monophosphate (PI-4-P or PtdIns4P), phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2 or PtdIns4,5P2), and phosphatidic acid (PtdOH), but not to 3- phosphoinositides. May function upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway. (2028 aa)
TIF3K1Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (226 aa)
CDC20-1Cell division cycle 20.1, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (457 aa)
PETsPlastid-specific ribosomal protein-7, chloroplastic; [Elongation factor Ts, chloroplastic]: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP (By similarity). It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity). (953 aa)
ELF5A-1Eukaryotic translation initiation factor 5A-1; The precise role of eIF-5A in protein biosynthesis is not known but it may function as a bimodular protein capable of binding to both RNA and proteins. Involved in xylogenesis. (158 aa)
FH7Formin-like protein 7; Might be involved in the organization and polarity of the actin cytoskeleton. (929 aa)
MEE14CCG-binding protein 1; Required for the development of the one-cell zygote and endosperm in embryos. Required for micropylar pollen tube guidance, but has no effect on ovule development and gametophytic cell fate specification. May connect transcription factors and the Pol II machinery to regulate pollen tube attraction, via its interactions with AGAMOUS-like (AGL) transcription factors, MEE14/CCG and the Mediator complex. (203 aa)
OTU6OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 6; Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Binds chromatin (e.g. nucleosomes and histones) and has enzymatic histone deubiquitinase activity, specific for the H2B histone. Can both repress (e.g. OSR2) and promote (e.g. AN3) the expression of target genes by associating with chromatin, deubiquitinating H2B and regulating its euchromatic histone marks (e.g. H3ac and H3K4me). In association wit [...] (505 aa)
ADF5Actin-depolymerizing factor 5; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (143 aa)
NET1CProtein NETWORKED 1C; Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex. (1111 aa)
F4C21.32Putative ubiquitin-like protein. (295 aa)
7SL2Ubiquitin domain-containing protein 7SL RNA2; Controls phase transition from the vegetative to the reproductive state. Involved in the maintenance of the shoot apical meristem (SAM) thus preventing inflorescence meristem (IM) formation and subsequent inflorescence stem development during flowering. Regulates leaf and organ morphology; Belongs to the ubiquitin family. (263 aa)
ADF6Actin-depolymerizing factor 6; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (146 aa)
ADF4Actin-depolymerizing factor 4; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. Contributes to the stochastic dynamic turnover of actin filaments. Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin. Involved in resistance triggered by the effector AvrPphB of Pseudomonas syringae pv tomato (Pst). May modulate the AvrPphB-RPS5-mediated defense signal transduction pathway. During AvrPphB-triggered resistance signaling pathway, involved in the control of MPK3 an [...] (139 aa)
ADF3Actin-depolymerizing factor 3; Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers. (139 aa)
7SL1Ubiquitin domain-containing protein 7SL RNA1. (275 aa)
AIP1-1Actin-interacting protein 1-1; Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins. (611 aa)
F9K20.24SecY protein transport family protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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