STRINGSTRING
GAT1-2 GAT1-2 LPD1 LPD1 FTSHI5 FTSHI5 LPD2 LPD2 PER1 PER1 NTRC NTRC PRXIID PRXIID ACHT3 ACHT3 CBSX1 CBSX1 PSBY PSBY ACHT4 ACHT4 CAT2 CAT2 EMB2360 EMB2360 GASA4 GASA4 GR1-2 GR1-2 NTR2 NTR2 NTR1 NTR1 PRXIIA PRXIIA Q8L923_ARATH Q8L923_ARATH ACHT2 ACHT2 ACHT1 ACHT1 WCRKC2 WCRKC2 MZN1.9 MZN1.9 PRXIIE PRXIIE BAS1 BAS1 CBSX2 CBSX2 2-Cys_Prx_B 2-Cys_Prx_B MHF15.5 MHF15.5 CBSX3 CBSX3 PRXQ PRXQ SCR SCR LPD2-2 LPD2-2 LPD1-2 LPD1-2 PRXIIF PRXIIF CITRX CITRX CDSP32 CDSP32 PRXIIC PRXIIC SELT SELT PRXIIB PRXIIB TRXF1 TRXF1 TRXF2 TRXF2 ACHT5 ACHT5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAT1-2Thioredoxin M3, chloroplastic; Thiol-disulfide oxidoreductase required for maintaining symplastic permeability in the meristem. Involved in redox regulation of callose deposition, plasmodesmata cell-to-cell communication and meristem maintenance. (173 aa)
LPD1Dihydrolipoyl dehydrogenase 1, chloroplastic; Lipoamide dehydrogenase is a component of the plastidial pyruvate dehydrogenase complex (PDC). (623 aa)
FTSHI5Probable inactive ATP-dependent zinc metalloprotease FTSHI 5, chloroplastic; Required for plastid development during embryogenesis. Might be involved in chaperone functions or play a structural role in the thylakoid FtsH complex (Probable). In the N-terminal section; belongs to the AAA ATPase family. (1320 aa)
LPD2Dihydrolipoyl dehydrogenase 2, chloroplastic; Lipoamide dehydrogenase is a component of the plastidial pyruvate dehydrogenase complex (PDC); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (567 aa)
PER11-Cys peroxiredoxin PER1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity). Seems to contribute to the inhibition of germination during stress. (216 aa)
NTRCNADPH-dependent thioredoxin reductase 3; Thioredoxin reductase (TR) that exhibits both TR and thioredoxin (Trx) activities. Contains a C-terminal functional Trx domain. Functions as an electron donor for plastidial 2-Cys peroxiredoxins and participates in a NADPH-dependent hydrogen peroxide scavenging system in chloroplasts in the dark. Required for chlorophyll biosynthesis and biogenesis of the photosynthetic apparatus. Activates aerobic cyclase which converts Mg-protoporhyrin monomethyl ester into protochlorophyllide. Involved in a light-dependent regulation of starch biosynthesis by [...] (529 aa)
PRXIIDPeroxiredoxin-2D; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (By similarity). May be involved in intracellular redox signaling (Probable). Belongs to the peroxiredoxin family. Prx5 subfamily. (162 aa)
ACHT3Thioredoxin-like 1-3, chloroplastic; Probable thiol-disulfide oxidoreductase that may participate in various redox reactions; Belongs to the thioredoxin family. (273 aa)
CBSX1CBS domain-containing protein CBSX1, chloroplastic. (236 aa)
PSBYPhotosystem II core complex proteins psbY, chloroplastic; PSBY-1 and -2 are manganese-binding polypeptides with L- arginine metabolizing enzyme activity. They are a component of the core of photosystem II. (189 aa)
ACHT4Thioredoxin-like 1-1, chloroplastic; Thiol-disulfide oxidoreductase that may participate in various redox reactions. Possesses insulin disulfide bonds reducing activity. (275 aa)
CAT2Catalase-2; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family. (492 aa)
EMB2360Glutathione reductase, chloroplastic; Maintains high levels of reduced glutathione in the chloroplast. (565 aa)
GASA4Gibberellin-regulated protein 4; Gibberellin-regulated protein involved in the regulation of floral meristem and floral organ identity, and promotion of seed size and weight. May play a role in the promotion of gibberellin responses such as regulation of flowering under short-day conditions, seed germination and inhibition of gibberellin oxidase. Possesses redox activity in E.coli and may function in redox regulation in planta. (106 aa)
GR1-2Glutathione reductase, cytosolic; Maintains high levels of reduced glutathione in the cytosol. (499 aa)
NTR2Thioredoxin reductase 2; Possesses thioredoxin-disulfide reductase activity towards thioredoxins O1, O2 and F3; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. (383 aa)
NTR1Thioredoxin reductase 1, mitochondrial; Possesses thioredoxin-disulfide reductase activity towards thioredoxins O1, O2 and F3. (375 aa)
PRXIIAPeroxiredoxin-2A; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (By similarity). May be involved in intracellular redox signaling (Probable). Belongs to the peroxiredoxin family. Prx5 subfamily. (553 aa)
Q8L923_ARATHAt3g14395. (75 aa)
ACHT2Thioredoxin-like 2-2, chloroplastic; Thiol-disulfide oxidoreductase that may participate in various redox reactions. Possesses insulin disulfide bonds reducing activity; Belongs to the thioredoxin family. (236 aa)
ACHT1Thioredoxin-like 2-1, chloroplastic; Thiol-disulfide oxidoreductase that may participate in various redox reactions. Possesses insulin disulfide bonds reducing activity; Belongs to the thioredoxin family. (221 aa)
WCRKC2Thioredoxin-like 3-2, chloroplastic; Probable thiol-disulfide oxidoreductase that may participate in various redox reactions; Belongs to the thioredoxin family. (192 aa)
MZN1.9Selenoprotein, Rdx type. (228 aa)
PRXIIEPeroxiredoxin-2E, chloroplastic; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (By similarity). May be involved in chloroplast redox homeostasis (Probable). (234 aa)
BAS12-Cys peroxiredoxin BAS1, chloroplastic; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (266 aa)
CBSX2CBS domain-containing protein CBSX2, chloroplastic. (238 aa)
2-Cys_Prx_B2-Cys peroxiredoxin BAS1-like, chloroplastic; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (273 aa)
MHF15.5Thioredoxin superfamily protein. (194 aa)
CBSX3CBS domain-containing protein CBSX3, mitochondrial. (206 aa)
PRXQPeroxiredoxin Q, chloroplastic; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Involved in the photosystem II protection against hydrogen peroxide; Belongs to the peroxiredoxin family. BCP/PrxQ subfamily. (216 aa)
SCRProtein SCARECROW; Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for cell division but not differentiation of the ground tissue. Also required for normal shoot gravitropism. Regulates the radial organization of the shoot axial organs. Binds to the promoter of MGP, NUC, RLK and SCL3. Restricts SHR movment and sequesters it into the nucleus of the endodermis. Belongs to the GRAS family. (653 aa)
LPD2-2Dihydrolipoyl dehydrogenase 2, mitochondrial; Lipoamide dehydrogenase is a component of the glycine decarboxylase (GDC) or glycine cleavage system as well as of the alpha- ketoacid dehydrogenase complexes. LPD1 is probably the protein most often associated with the glycine decarboxylase complex while LPD2 is probably incorporated into alpha-ketoacid dehydrogenase complexes. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (507 aa)
LPD1-2Dihydrolipoyl dehydrogenase 1, mitochondrial; Lipoamide dehydrogenase is a component of the glycine decarboxylase (GDC) or glycine cleavage system as well as of the alpha- ketoacid dehydrogenase complexes. LPD1 is probably the protein most often associated with the glycine decarboxylase complex while LPD2 is probably incorporated into alpha-ketoacid dehydrogenase complexes. (507 aa)
PRXIIFPeroxiredoxin-2F, mitochondrial; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Reduces preferentially hydrogen peroxide rather than alkyl peroxides. May be involved in mitochondrial redox homeostasis. (201 aa)
CITRXThioredoxin-like protein CITRX, chloroplastic; Thiol-disulfide oxidoreductase that plays a role in proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription. Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression. May be involved in cell death and defense responses (By similarity). (183 aa)
CDSP32Thioredoxin-like protein CDSP32, chloroplastic; Probable thiol-disulfide oxidoreductase involved in resistance to oxidative stress. May participate in the reduction of alkyl hydroperoxides derived from oxidative stress by acting as a physiological electron donor to the BAS1 peroxiredoxin. May regenerate methionine sulfoxide reductase B1 (MSRB1) activity through sulfenic acid reduction; Belongs to the thioredoxin family. (302 aa)
PRXIICPeroxiredoxin-2C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events; Belongs to the peroxiredoxin family. Prx5 subfamily. (162 aa)
SELTSelT-like protein; Belongs to the SelWTH family. SELT subfamily. (209 aa)
PRXIIBPeroxiredoxin-2B; Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin or glutaredoxin system. May be involved in intracellular redox signaling. (162 aa)
TRXF1Thioredoxin F1, chloroplastic; Thiol-disulfide oxidoreductase involved in the redox regulation of enzymes of both reductive pentose phosphate pathway (Calvin-Benson cycle) and oxidative pentose phosphate pathway. Under light or reducing conditions, activates in chloroplast the glyceraldehyde-3-phosphate dehydrogenase, the phosphoribulokinase and the fructose-1,6-bisphosphate phosphatase, and inhibits the glucose-6- phosphate dehydrogenase. (178 aa)
TRXF2Thioredoxin F2, chloroplastic; Probable thiol-disulfide oxidoreductase involved in the redox regulation of enzymes of both reductive pentose phosphate pathway (Calvin-Benson cycle) and oxidative pentose phosphate pathway. (185 aa)
ACHT5Thioredoxin-like 1-2, chloroplastic; Probable thiol-disulfide oxidoreductase that may participate in various redox reactions; Belongs to the thioredoxin family. (245 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (12%) [HD]