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| | AZF1 | Zinc finger protein AZF1; Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions. Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner. (245 aa) |
| | RAV1 | AP2/ERF and B3 domain-containing transcription factor RAV1; Binds specifically to bipartite recognition sequences composed of two unrelated motifs, 5'-CAACA-3' and 5'-CACCTG-3'. May function as negative regulator of plant growth and development. Belongs to the AP2/ERF transcription factor family. RAV subfamily. (344 aa) |
| | F5O8.36 | Paired amphipathic helix (PAH2) superfamily protein. (241 aa) |
| | OFP7 | Transcription repressor OFP7; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (315 aa) |
| | GRH1 | GRR1-like protein 1; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. Involved in embryogenesis regulation by auxin. Confers sensitivity to the virulent bacterial pathogen P.syringae. Mediates glucose repression in yeast. (585 aa) |
| | OTU6 | OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 6; Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Binds chromatin (e.g. nucleosomes and histones) and has enzymatic histone deubiquitinase activity, specific for the H2B histone. Can both repress (e.g. OSR2) and promote (e.g. AN3) the expression of target genes by associating with chromatin, deubiquitinating H2B and regulating its euchromatic histone marks (e.g. H3ac and H3K4me). In association wit [...] (505 aa) |
| | SNL6 | Paired amphipathic helix protein Sin3-like 6; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1173 aa) |
| | SNL5 | Paired amphipathic helix protein Sin3-like 5; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1162 aa) |
| | WRKY42 | WRKY transcription factor 42; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression. (528 aa) |
| | HSFB2B | Heat stress transcription factor B-2b; Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). (377 aa) |
| | MYB4 | Transcription repressor MYB4; Transcription repressor involved in regulation of protection against UV. Mediates transcriptional repression of CYP73A5, the gene encoding trans-cinnamate 4-monooxygenase, thereby regulating the accumulation of the UV-protectant compound sinapoylmalate. (282 aa) |
| | NFYA5 | Nuclear transcription factor Y subunit A-5; Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity). Involved in the blue light (BL) and abscisic acid (ABA) signaling pathways. (308 aa) |
| | F14N23.13 | Paired amphipathic helix Sin3-like protein. (77 aa) |
| | SNI1 | Negative regulator of systemic acquired resistance SNI1; Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Transcription repressor that prevents expression of pathogenesis-related genes (PR) via histone modifications and binding negative cis-acting elements at their promoters. Negative regulator of hypersensitive response (HR) and systemic acquired resistance (SAR) required to dampen the basal expression of pathogenesis related (PR) genes. Functions synergistically with NTL9/CBNAC as negative regulator of pathogen- [...] (432 aa) |
| | RAP2-10 | Ethylene-responsive transcription factor RAP2-10; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity); Belongs to the AP2/ERF transcription factor family. ERF subfamily. (196 aa) |
| | RBG2 | Glycine-rich RNA-binding protein 2, mitochondrial; Plays a role in RNA transcription or processing during stress. Binds RNAs and DNAs sequence with a preference to single- stranded nucleic acids. Displays strong affinity to poly(U) sequence. Exerts cold and freezing tolerance, probably by exhibiting an RNA chaperone activity during the cold and freezing adaptation process. Belongs to the GR-RBP family. (158 aa) |
| | F22O6_70 | Transcription repressor OFP15-like protein. (178 aa) |
| | OFP18 | Transcription repressor OFP18; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (282 aa) |
| | AFPH2 | AFP homolog 2; Acts as a transcriptional repressor. Negative regulator of jasmonate responses. Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors; Belongs to the Ninja family. (425 aa) |
| | DEK3 | DEK domain-containing chromatin associated protein. (763 aa) |
| | MRF4 | MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 4; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Belongs to the PDCD4 family. (633 aa) |
| | AZF2 | Zinc finger protein AZF2; Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions. Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner. Acts as a negative regulator of abscisic acid (ABA) signaling during seed germination. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key [...] (273 aa) |
| | AZF3 | Zinc finger protein AZF3; Transcriptional repressor probably involved in abiotic stress responses. Binds DNA in a sequence-specific manner and can repress the transactivation activity of other transcription factors. (193 aa) |
| | SNL1 | Paired amphipathic helix protein Sin3-like 1; Acts as a transcriptional repressor. An histone deacetylase (HDAC) activity is required for transcription repression. May play a role in telomere stability. (1372 aa) |
| | NAC052 | NAC domain containing protein 52; Transcriptional repressor that binds to the motif 5'- (C/T)A(C/A)G-3' in the promoter of target genes. Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin. Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing. Regulat [...] (451 aa) |
| | NAC050 | NAC domain containing protein 50; Transcriptional repressor that binds to the motif 5'- (C/T)A(C/A)G-3' in the promoter of target genes. Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin. Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing. (447 aa) |
| | LUX | Transcription factor LUX; Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 a [...] (323 aa) |
| | T8P19.20 | AtIII18x5-like protein. (294 aa) |
| | T8P19.220 | DEK domain-containing chromatin associated protein. (462 aa) |
| | OFP16 | Transcription repressor OFP16; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (244 aa) |
| | MED18 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general [...] (219 aa) |
| | PAR1 | Transcription factor PAR1; Atypical bHLH transcription factor that acts as negative regulator of a variety of shade avoidance syndrome (SAS) responses, including seedling elongation and photosynthetic pigment accumulation. Acts as direct transcriptional repressor of two auxin-responsive genes, SAUR15 and SAUR68. May function in integrating shade and hormone transcriptional networks in response to light and auxin changes. (118 aa) |
| | OFP15 | Transcription repressor OFP15; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (261 aa) |
| | SPEAR4 | Protein SPEAR4; Adapter-like transcriptional repressor recruiting TPL/TPR coepressors to inhibit TCP transcription factors (By similarity). May be involved in leaf development. (300 aa) |
| | GRXC9 | Glutaredoxin-C9; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). (137 aa) |
| | WRKY40 | Probable WRKY transcription factor 40; Transcription factor (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor- responsive cis-acting element (By similarity). (302 aa) |
| | AFP4 | Ninja-family protein AFP4; Acts as a negative regulator of abscisic acid (ABA) and salinity responses; Belongs to the Ninja family. (319 aa) |
| | OFP14 | Transcription repressor OFP14; Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (294 aa) |
| | MYB3R1 | Transcription factor MYB3R-1; Transcription factor that binds 5'-AACGG-3' motifs in gene promoters. Transcription activator involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells. Required for the maintenance of diploidy. (776 aa) |
| | PKL | CHD3-type chromatin-remodeling factor PICKLE; Chromatin remodeling factor that represses the expression of embryonic trait genes (such as NFYB9/LEC1) upon and after seed germination and thus enables the developmental switch to post- germinative growth. Silences some MADS-box proteins such as PHE1 and PHE2. Plays a role during carpel differentiation. Regulates late processes in cytokinin signaling. (1384 aa) |
| | CSTF64 | Cleavage stimulating factor 64; One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3' non-coding region. Required for the targeted 3' processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene. (461 aa) |
| | NSN1 | Guanine nucleotide-binding protein-like NSN1; Involved in the differentiation of epidermal cells, probably via the regulation of the expression of meristem-related genes (e.g. CLV3, STM, KNAT1, CUC2 and AG) and of leaf polarity-related genes (e.g. YAB5, FIL, AS2, PHB and PHV). May play a role in regulating cellular proliferation (By similarity). Necessary for flower development, probably by preventing apical dominance through the down-regulation of AG expression. Required for embryogenesis, leaf and cotyledon development, as well as for leaf polarity establishment. Plays an important r [...] (582 aa) |
| | F13E7.20 | Zinc ion binding protein. (313 aa) |
| | HDT4 | Histone deacetylase HDT4; Probably mediates the deacetylation of lysine residues lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (203 aa) |
| | DDB1A | DNA damage-binding protein 1a; Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB). Component of the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin-protein [...] (1088 aa) |
| | MYB41 | Transcription factor MYB41; Transcription factor involved in salt stress response. Confers tolerance to salt stress. Involved in distinct cellular processes in response to osmotic stress, including control of primary metabolism and negative regulation of short-term transcriptional responses to osmotic stress. Can activate the steps necessary for aliphatic suberin synthesis and deposition of cell wall-associated suberin-like lamellae. Involved in the production of aliphatic suberin under abiotic stress conditions. (282 aa) |
| | OFP1 | Transcription repressor OFP1; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. Controls the subcellular localization of the homeodomain protein BLH1. Plays a role in the regulation of cell elongation by controlling the expression of GA20OX1, a gene that encodes a key enzyme in gibberellin biosynthesis. May play a role in double-stranded DNA repair through the DNA non- homologous end joining (NHEJ) pathway along with KU70 and KU80 protein complex. Po [...] (270 aa) |
| | HDT3 | Histone deacetylase HDT3; Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Involved in the modulation of abscisic acid and stress-responsive genes. (294 aa) |
| | BLH9 | BEL1-like homeodomain protein 9; Transcription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patternin [...] (575 aa) |
| | SIR | Assimilatory sulfite reductase (ferredoxin), chloroplastic; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (642 aa) |
| | EMF1 | Protein EMBRYONIC FLOWER 1; Transcription repressor that regulates phase transition during shoot, flower and seeds development. Controls leaves development, shoot architecture and flowering by delaying both the vegetative to reproductive transition and flower initiation. Participates in polycomb group (PcG) protein complex-mediated (including EMF2) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegeta [...] (1096 aa) |
| | GRXS6 | Monothiol glutaredoxin-S6; May only reduce GSH-thiol disulfides, but not protein disulfides; Belongs to the glutaredoxin family. CC-type subfamily. (102 aa) |
| | GRXC11 | Glutaredoxin-C11; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. CC-type subfamily. (103 aa) |
| | WRKY70 | Probable WRKY transcription factor 70; Transcription factor involved in senescence, biotic and abiotic stress responses by modulating various phytohormones signaling pathways. Interacts specifically with the W box (5'- (T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Binds to the 5'-[CT]GACTTTT-3' motif in promoters of target genes to induce their expression. Plays an important but not indispensable role in jasmonate and salicylic acid signaling. Regulates positively the salicylic acid (SA)-mediated signal pathway, but negatively the jasmo [...] (294 aa) |
| | HAM2 | Histone acetyltransferase of the MYST family 2; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac). Essential for gametophyte development. Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin. Belongs to the MYST (SAS/MOZ) family. (445 aa) |
| | KUA1 | Transcription factor KUA1; Transcriptional repressor. Direct regulator of the transcription of peroxidase (Prxs) and reactive oxygen species (ROS)-related genes via the recognition of 5'-ATCACA-3' motif. Binds to 5'-TATCCA-3' motif (TA box) and represses the activity of corresponding promoters (e.g. sugar response genes). Regulates hypocotyl elongation in response to darkness by enhancing auxin accumulation in a phytochrome-interacting factor (PIF) proteins-dependent manner. Promotes lateral roots formation. Promotes cell expansion during leaves development via the modulation of cell w [...] (365 aa) |
| | OFP3 | Transcription repressor OFP3; Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (296 aa) |
| | EMB1789 | Zinc finger CCCH domain-containing protein 65; Possesses RNA-binding and ribonuclease activities in vitro. (675 aa) |
| | FIE | Polycomb group protein FERTILIZATION-INDEPENDENT ENDOSPERM; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Required to prevent the proliferation of the central cell by repressing unknown target genes before fertilization. Pr [...] (369 aa) |
| | SCRM | Transcription factor ICE1; Transcriptional activator that regulates the cold-induced transcription of CBF/DREB1 genes. Binds specifically to the MYC recognition sites (5'-CANNTG-3') found in the CBF3/DREB1A promoter. Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA. Functions as a dimer with SPCH during stomatal initiation. (494 aa) |
| | AFP1 | Ninja-family protein AFP1; Acts as a negative regulator of abscisic acid (ABA) response during germination through the ubiquitin-mediated proteolysis of ABI5/DPBF1; Belongs to the Ninja family. (345 aa) |
| | AFP2 | Ninja-family protein AFP2; Acts as a negative regulator of abscisic acid (ABA) response during germination through the ubiquitin-mediated proteolysis of ABI5/DPBF1. (348 aa) |
| | Q9LK28_ARATH | At3g27250. (282 aa) |
| | Q9LK19_ARATH | Paired amphipathic helix Sin3-like protein. (374 aa) |
| | BBX32 | B-box zinc finger protein 32; Repressor of light-mediated regulation of seedling development. Functions by suppressing the activities of positive cofactors like BBX21 and HY5 involved in modulating light-regulated gene expression and growth. (225 aa) |
| | GRXS10 | Monothiol glutaredoxin-S10; May only reduce GSH-thiol disulfides, but not protein disulfides; Belongs to the glutaredoxin family. CC-type subfamily. (102 aa) |
| | SNL2 | Paired amphipathic helix protein Sin3-like 2; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1367 aa) |
| | F2G14.160 | Paired amphipathic helix (PAH2) superfamily protein. (87 aa) |
| | T27I15_140 | Calcium-dependent lipid-binding (CaLB domain) family protein. (510 aa) |
| | ERF7 | Ethylene-responsive transcription factor 7; Involved in the regulation of gene expression by abscisic acid, stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis- related promoter element. Part of a transcriptional repressor complex including a histone deacetylase. (244 aa) |
| | F17L21.5 | Paired amphipathic helix (PAH2) superfamily protein. (241 aa) |
| | WRKY75 | Probable WRKY transcription factor 75; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity); Belongs to the WRKY group II-c family. (145 aa) |
| | NAC083 | NAC domain-containing protein 83; Transcriptional repressor that negatively regulates the expression of genes involved in xylem vessel formation. Represses the transcriptional activation activity of NAC030/VND7, which regulates protoxylem vessel differentiation by promoting immature xylem vessel- specific genes expression. Transcriptional activator that regulates the COLD-REGULATED (COR15A and COR15B) and RESPONSIVE TO DEHYDRATION (LTI78/RD29A and LTI65/RD29B) genes by binding directly to their promoters. Mediates signaling crosstalk between salt stress response and leaf aging process. [...] (252 aa) |
| | HRS1 | Transcription factor HRS1; Transcription factor involved in nitrate and phosphate signaling in roots. Integrates nitrate and phosphate starvation responses and adaptation of root architecture depending on nutrient availabilities. Acts downstream of the nitrate sensor and transporter NPF6.3/NRT1.1. Represses primary root development in response to phosphate deficiency conditions, only when nitrate is present. Involved in the modulation of primary root and root hair growth in phosphate-deprived environement. May be required for suppressing abscisic acid (ABA) signaling in germinating emb [...] (344 aa) |
| | HDT1 | Histone deacetylase HDT1; Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for histone H3 'Lys-9' deacetylation. Involved in rRNA gene silencing in nucleolar dominance. Seems to be implicated in the regulation of genes involved in seeds development; Belongs to the histone deacetylase HD2 family. (245 aa) |
| | SVP | MADS-box protein SVP; Transcription repressor that inhibit floral transition in the autonomous flowering pathway, independent of photoperiod and temperature. Acts in a dosage-dependent manner. Together with AGL24 and AP1, controls the identity of the floral meristem and regulates expression of class B, C and E genes. Promotes EFM expression to suppress flowering. (240 aa) |
| | LUG | Transcriptional corepressor LEUNIG; Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development. Implicated in embryo and floral development. Involved in post-synthesis cell wall modifications necessary for mucilage ext [...] (931 aa) |
| | KNAT7 | Homeobox protein knotted-1-like 7; May be involved in secondary cell wall biosynthesis. (291 aa) |
| | NIMIN-1 | Protein NIM1-INTERACTING 1; Belongs to the NPR1-interactor family. (142 aa) |
| | ILP1 | Transcriptional repressor ILP1; Transcriptional repressor regulating endoreduplication through control of A-type cyclins expression. Does not bind to promoter sequences (in vitro) and may act by interacting with tissue-specific transcription factors. Enhances the endocycle in endoreduplicating cells in seedlings. Required for efficient splicing. Belongs to the GCF family. (908 aa) |
| | DPA4 | B3 domain-containing protein At5g06250. (282 aa) |
| | MHF15.21 | Putative B-type cyclin. (122 aa) |
| | ATXR6 | Histone-lysine N-methyltransferase ATXR6; Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. May act as a positive regulator of the G1-S transition. Influences which sets of rRNA gene variants are expressed or silenced. Up-regulated by E2FB. (349 aa) |
| | HOS15 | WD40 repeat-containing protein HOS15; Acts as repressor of cold stress-regulated gene expression. Interacts specifically with and promotes deacetylation of histone H4. Plays a role in gene regulation for plant acclimation and tolerance to cold stress. (613 aa) |
| | OFP10 | Transcription repressor OFP10; Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (196 aa) |
| | OFP13 | Transcription repressor OFP13; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (260 aa) |
| | WRKY27 | Probable WRKY transcription factor 27; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity); Belongs to the WRKY group II-e family. (348 aa) |
| | HAM1 | Histone acetyltransferase of the MYST family 1; Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac). Essential for gametophyte development. Involved in DNA repair after UV-B exposure. Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin. (445 aa) |
| | RING1A | Putative E3 ubiquitin-protein ligase RING1a; Putative E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119ub), thereby playing a central role in histone code and gene regulation. (522 aa) |
| | MHK7.2 | Emb|CAB62340.1. (303 aa) |
| | MHK7.3 | Emb|CAB62340.1. (272 aa) |
| | MYB36 | Transcription factor MYB36; Transcription factors that activates genes required for endodermal differentiation but represses genes involved in proliferative divisions, thus regulating the transition from proliferation to differentiation in root endodermis. Required for Casparian strip formation by positively regulating the expression of the Casparian strip genes CASP1, PER64 and ESB1 and other endodermis-specific genes, thus triggering correct localized lignin biosynthesis in root endodermis and subsequently regulating global ion homeostasis. (333 aa) |
| | MXI22.7 | Von willebrand factor A domain protein. (291 aa) |
| | MJE4.6 | Paired amphipathic helix (PAH2) superfamily protein. (155 aa) |
| | MNJ8.20 | Chaperone DnaJ-domain superfamily protein. (431 aa) |
| | GTE10 | Transcription factor GTE10; Acts as a negative regulator in plant response to changes in environmental conditions through the control of ABA-regulated gene expression. (1061 aa) |
| | MLE2.18 | DEK domain-containing chromatin associated protein. (531 aa) |
| | RLT2 | Homeobox-DDT domain protein RLT2; Transcriptional regulator required for the maintenance of the plant vegetative phase. In association with CHR11 or CHR17 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Involved in the transcriptional regulation of seed-specific gene expression. (1694 aa) |
| | SRT1 | NAD-dependent protein deacetylase SRT1; NAD-dependent protein deacetylase. Has deacetylase activity towards H3K9Ac. May have a function in the safeguard against genome instabiliy and DNA damage to ensure plant cell growth (By similarity). Belongs to the sirtuin family. Class IV subfamily. (473 aa) |
| | MIF1 | Mini zinc finger protein 1; Inhibits zinc finger homeodomain (ZHD) transcription factors, such as ZHD5, by interacting with them to prevent both their nuclear localization and their DNA-binding properties. Involved in integrating signals from multiple hormones by preventing the expression of genes involved in gibberellic acid (GA), auxin and brassinosteroid signaling and by promoting the expression of abscisic acid (ABA)-responsive genes. Regulates several development aspects, including photomorphogenesis, apical dominance, longevity, flower morphology and fertility, as well as root an [...] (102 aa) |
| | MYB62 | Transcription factor MYB62; Transcription repressor of phosphate (Pi) starvation-induced genes. Regulates negatively Pi starvation responses via the repression of gibberellic acid (GA) biosynthesis and signaling. Modulates root architecture, phosphatase activity, and Pi uptake and accumulation. (286 aa) |
| | GTL1 | Trihelix transcription factor GTL1; Transcription repressor that binds specific DNA sequence such as GT3 box 5'-GGTAAA-3' in the SDD1 promoter. Negative regulator of water use efficiency (WUE) via the promotion of stomatal density and distribution by the transcription repression of SDD1. Regulates the expression of several cell cycle genes and endoreduplication, especially in trichomes where it prevents ploidy-dependent plant cell growth. (587 aa) |
| | MYB20 | Transcription factor MYB20; Transcription factor that acts as positive regulator of abscisic acid (ABA) signaling in response to salt stress. Acts as negative regulator ABI1, ABI2 and PP2CA, which are protein phosphatases 2C acting as negative regulator of ABA signaling. Binds to the DNA specific sequence and core element 5'-ACGT-3' found in the promoters of ABI1 and PP2CA to negatively regulate their expression during ABA- dependent salt stress response. (282 aa) |
| | NAC081 | Protein ATAF2; Involved in disease resistance response. May function as repressor of pathogenesis-related proteins. May function in the regulation of host basal defense responses against viral infection. Transcriptional activator involved in responses to wounding and infection with tobamovirus (TMV). Binds to the DNA sequences 5'-AAAATATCT-3' and 5'AGATTTTT-3' of CYP734A1/BAS1 and CYP72C1/SOB7 promoters, respectively. Acts as suppressor of the brassinosteroid (BR)-inactivating enzymes CYP734A1/BAS1 and CYP72C1/SOB7, and prevents their expression in almost all tissues. Plays a central r [...] (283 aa) |
| | WRKY6 | WRKY transcription factor 6; Transcription factor involved in the control of processes related to senescence and pathogen defense. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes. Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression ; Belongs to the WRKY group II-b family. (553 aa) |
| | HSFB1 | Heat stress transcription factor B-1; Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE); Belongs to the HSF family. Class B subfamily. (284 aa) |
| | GRXC7 | Glutaredoxin-C7; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Involved in flower development as a regulator of petal primorida initiation and further petal morphogenesis. May mediate post-translational modifications of target proteins required for normal petal organ initiation and morphogenesis. ROXY1/TGA protein interactions can occur in vivo and support their biological relevance in petal development. May be involved in the regulation of the floral regulato [...] (136 aa) |
| | ZAT10 | Zinc finger protein ZAT10; Transcriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. (227 aa) |
| | ARF2 | Auxin response factor 2; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. (859 aa) |
| | AFP3 | Ninja-family protein AFP3; Acts as a negative regulator of abscisic acid (ABA) response and stress responses. (231 aa) |
| | MRF1 | MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 1; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. (702 aa) |
| | SLK2 | Probable transcriptional regulator SLK2; Probable transcription regulator that functions in the development of the carpel margin meristem similarly to SEUSS (SEU). In association with SEU, supports organ development from meristematic regions by facilitating auxin response and thus organ initiation, and by sustaining meristematic potential through the maintenance of PHABULOSA expression. DNA-binding adapter subunit of the SEU-SLK2 transcriptional corepressor of abiotic stress (e.g. salt and osmotic stress) response genes. (816 aa) |
| | T5J17.220 | Signal transducer, putative (DUF3550/UPF0682). (599 aa) |
| | TPL | Protein TOPLESS; Transcriptional corepressor. May repress the expression of root-promoting genes in the top half of the embryo to allow proper differentiation of the shoot pole during the transition stage of embryogenesis. Regulates the expression of PLT1 and PLT2. Negative regulator of jasmonate responses. Negative regulator of auxin responses. Negative regulator of multiple floral organ identity genes. Required for ovule development. (1131 aa) |
| | LHP1 | Chromo domain-containing protein LHP1; Structural component of heterochromatin involved in gene repression, including several floral homeotic genes and FLT that regulates flowering time. Required for maintenance of vernalization- induced repression of FLC. As part of the PRC1-like complex, recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me), leading to epigenetic repression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling a [...] (445 aa) |
| | NFYA9 | Nuclear transcription factor Y subunit A-9; Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. (303 aa) |
| | HDA14 | Histone deacetylase 14; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (423 aa) |
| | APRR7 | Two-component response regulator-like APRR7; Transcriptional repressor of CCA1 and LHY, and positive regulator of LWD1 and LWD2 expression. Represses the expression of other clock proteins and master regulators of plant growth, development and response to abiotic stress. Involved in the positive and negative feedback loops of the circadian clock. Controls photoperiodic flowering response and temperature compensation. Expression of several members of the ARR-like family is controlled by circadian rhythm. APRR9, APRR7, and APRR5 coordinately act on the upstream region of the target genes [...] (727 aa) |
| | MRF3 | MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 3; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Involved in the regulation of the ethylene-mediated signaling pathway. Involved in salt stress responses. Reduced cotyledons size and early flowering. (702 aa) |
| | VAL1 | B3 domain-containing transcription repressor VAL1; Transcriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL2/HSL1. (790 aa) |
| | SEU | Transcriptional corepressor SEUSS; DNA-binding adapter subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and LEUNIG to repress AGAMOUS expression. In association with LUG, regulates petal shape through AGAMOUS-independent mechanisms. Controls cell division during petal development and enable the proper patterning of petal [...] (877 aa) |
| | CDF1 | Cyclic dof factor 1; Transcription factor that binds specifically to a 5'-AA[AG]G- 3' consensus core sequence. A flanking TGT sequence contributes to the specificity of binding. Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The DNA-binding ability is not modulated by 'GIGANTEA' but the stability of CDF1 is controlled by the proteasome-dependent pathway. Ubiquitinated by the SCF(ADO3) E3 ubiquitin ligase complex. Binds to the FT promoter in the morning. (298 aa) |
| | HHO2 | Transcription factor HHO2; Probable transcription factor involved in phosphate homeostasis. Involved in the regulation of the developmental response of lateral roots, acquisition and/or mobilization of phosphate and expression of a subset of genes involved in phosphate sensing and signaling pathway. Is a target of the transcription factor PHR1. (354 aa) |
| | OFP5 | Transcription repressor OFP5; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. Required for embryo development. (349 aa) |
| | SWC4 | SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. (441 aa) |
| | ATXR5 | Histone-lysine N-methyltransferase ATXR5; Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has much higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. Influences which sets of rRNA gene variants are expressed or silenced; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (379 aa) |
| | T18B16.160 | Uncharacterized zinc finger CCHC domain-containing protein At4g19190. (595 aa) |
| | ASR3 | Trihelix transcription factor ASR3; Transcriptional repressor that binds DNA and plays a negative role in regulating microbe-associated molecular patterns-(MAMPs, e.g. flg22, elf18, chitin, and LPS) triggered immunity (PTI) by negatively regulating immune gene expression. (314 aa) |
| | NFYA4 | Nuclear transcription factor Y subunit A-4; Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. (198 aa) |
| | LDL1 | Lysine-specific histone demethylase 1 homolog 1; Probable histone demethylase that reduces the levels of histone H3 'Lys-4' methylation in chromatin of the floral repressor FLOWERING LOCUS C (FLC) and the sporophytically silenced floral repressor FWA. Seems to act in partial redundancy with FLOWERING LOCUS D (FLD) to repress FLC expression. Required for cytosine methylation of FWA. Controls primary seed dormancy by regulating DOG1 and abscisic acid signaling-related genes. In association with OTU6/OTLD1, involved in transcriptional gene repression via histone deubiquitination and demet [...] (844 aa) |
| | Q8S8S8_ARATH | Zinc ion binding protein. (275 aa) |
| | BZR1 | Protein BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2). (336 aa) |
| | F25E4.180 | Bromo-adjacent homology (BAH) domain-containing protein. (587 aa) |
| | F7G19.8 | Arginine-glutamic acid dipeptide repeat protein. (916 aa) |
| | HDA5 | Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (660 aa) |
| | RZ1C | Glycine-rich RNA-binding protein RZ1C; Binds RNA and DNA sequences non-specifically. May be involved in tolerance to cold stress. (310 aa) |
| | HDA18 | Histone deacetylase 18; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for appropriate cellular patterning in the root epidermis. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (682 aa) |
| | GRXC8 | Glutaredoxin-C8; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Involved in flower development; Belongs to the glutaredoxin family. CC-type subfamily. (140 aa) |
| | F3I6.14 | Paired amphipathic helix (PAH2) superfamily protein. (155 aa) |
| | GATA18 | GATA transcription factor 18; Transcriptional factor that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (including its own promoter and GATA21 promoter), thus regulating the expression of genes mostly involved in hormone responses and floral organ specification (including genes regulating hormones responses). Regulates both flower and shoot apical meristem (SAM) development, especially for establishing organ boundaries in shoots and flowers, probably by controlling the number and position of WUS- expressing cells. Coregulates, with AGO10/PNH, the shoot apical [...] (295 aa) |
| | COR28 | Cold-regulated protein 28; Together with COR27, involved in central circadian clock regulation and in flowering promotion, by binding to the chromatin of clock-associated evening genes TOC1, PRR5, ELF4 and cold-responsive genes in order to repress their transcription. Negative regulator of freezing tolerance. (218 aa) |
| | GRXS2 | Monothiol glutaredoxin-S2; May only reduce GSH-thiol disulfides, but not protein disulfides; Belongs to the glutaredoxin family. CC-type subfamily. (102 aa) |
| | COR27 | Cold-regulated protein 27; Together with COR28, involved in central circadian clock regulation and in flowering promotion, by binding to the chromatin of clock-associated evening genes TOC1, PRR5, ELF4 and cold-responsive genes in order to repress their transcription. Negative regulator of freezing tolerance. (246 aa) |
| | ARF1-2 | Auxin response factor 1; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7. (665 aa) |
| | APRR9 | Two-component response regulator-like APRR9; Transcriptional repressor of CCA1 and LHY, and positive regulator of LWD1 and LWD2 expression. Controls photoperiodic flowering response and temperature compensation. Involved in the positive and negative feedback loops of the circadian clock. Expression of several members of the ARR-like family is controlled by circadian rhythm. Regulated at the transcriptional level by a corepressor complex consisting of ELF4, ELF3, and LUX. APRR9, APRR7, and APRR5 coordinately act on the upstream region of the target genes to repress their expression from [...] (468 aa) |
| | MYB3R3 | Transcription factor MYB3R-3; Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells. (505 aa) |
| | F17A22.21 | Arginine-glutamic acid dipeptide repeat protein. (805 aa) |
| | ARF31 | B3 domain-containing protein At2g36080. (244 aa) |
| | HDA15 | Histone deacetylase 15; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (552 aa) |
| | F21M11.33 | Prefoldin chaperone subunit family protein. (391 aa) |
| | HSBP | Heat shock factor-binding protein; Negative regulator of the heat shock (HS) response. Affects negatively HSFA1B DNA-binding capacity in vitro. Involved in acquired thermotolerance but not basal thermotolerance. Crucial for seed development, after fertilization and during embryogenesis. Belongs to the HSBP1 family. (86 aa) |
| | CSTF77 | Cleavage stimulation factor subunit 77; One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3' processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene. (734 aa) |
| | JMJ14 | Probable lysine-specific demethylase JMJ14; Transcriptional repressor. Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a higher activity for H3K4me3 and H3K4me2 than H3K4me1. No activity on H3K9me3/2, H3K36me3/2 and H3K27me3/2. Represses FT and TSF expression to inhibit the floral transition. Binds around the transcription start site of the FT locus. Involved in the DRM2-mediated maintenance of DNA methylation, but not required for the de novo DNA methylation. Required for demethylating histone H3K4me3 at the target of RNA silencing. Together with NAC051/NAC05 [...] (954 aa) |
| | SPEAR1 | Protein SPEAR1; Adapter-like transcriptional repressor recruiting TPL/TPR corepressors to inhibit TCP transcription factors. (178 aa) |
| | GRXS13 | Monothiol glutaredoxin-S13; May only reduce GSH-thiol disulfides, but not protein disulfides. (150 aa) |
| | OFP17 | Transcription repressor OFP17; Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (195 aa) |
| | F20P5.23 | Paired amphipathic helix (PAH2) superfamily protein. (160 aa) |
| | HOS1 | E3 ubiquitin-protein ligase HOS1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways. Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels. (927 aa) |
| | NFYA7 | Nuclear transcription factor Y subunit A-7; Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters; Belongs to the NFYA/HAP2 subunit family. (190 aa) |
| | MYB3R5 | Transcription factor MYB3R-5; Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells. (548 aa) |
| | SPEAR3 | Protein SPEAR3; Transcriptional regulator of leaf development. Acts as an adapter-like transcriptional repressor recruiting TPL/TPR corepressors to inhibit the CIN-like TCP transcription factors. (193 aa) |
| | CPL1 | RNA polymerase II C-terminal domain phosphatase-like 1; Processively dephosphorylates 'Ser-5' but not 'Ser-2' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II. Together with CPL2, required for male gametes fertility. Multifunctional regulator that modulates plant growth, stress, and phytohormones responses. Negative regulator of stress gene transcription involved in abscisic acid (ABA) mediated and jasmonic acid (JA) mediated signaling pathways, NaCl, osmotic stress, wounding, and col [...] (967 aa) |
| | AL5 | PHD finger protein ALFIN-LIKE 5; Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. (260 aa) |
| | HDT2 | Histone deacetylase HDT2; Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events; Belongs to the histone deacetylase HD2 family. (306 aa) |
| | PRL1 | Protein pleiotropic regulatory locus 1; Pleiotropic regulator of glucose, stress and hormone responses. Also regulates cytochrome P450 CYP90A1/CPD. Coordinates the expression of hormone- and stress-related genes and genes related to cell wall modification and growth, leading to altered sugar-dependent growth and developmental responses. Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. By suppressing the expression of several (1)O(2)-responsive genes, PRL1 seems to play a major role [...] (486 aa) |
| | OFP6 | Transcription repressor OFP6; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (159 aa) |
| | OFP8 | Transcription repressor OFP8; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (221 aa) |
| | AGL15 | Agamous-like MADS-box protein AGL15; Transcription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence- specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can [...] (268 aa) |
| | IAA14 | Auxin-responsive protein IAA14; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (228 aa) |
| | IAA12 | Auxin-responsive protein IAA12; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (239 aa) |
| | YY1 | Zinc finger transcription factor YY1; Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3'. Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea). Binds to ABR1 promoter and promotes its expression, thus negatively r [...] (387 aa) |
| | TPR4 | Topless-related protein 4; Transcription corepressor of Zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling. (1135 aa) |
| | Q1G3W7_ARATH | Transcription repressor OFP17-like protein. (170 aa) |
| | RING1B | Putative E3 ubiquitin-protein ligase RING1b; Putative E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119ub), thereby playing a central role in histone code and gene regulation. (460 aa) |
| | SLK1 | Probable transcriptional regulator SLK1; Probable transcription regulator that functions in the development of the carpel margin meristem similarly to SEUSS (SEU). In association with SEU, supports organ development from meristematic regions by facilitating auxin response and thus organ initiation, and by sustaining meristematic potential through the maintenance of PHABULOSA expression. DNA-binding adapter subunit of the SEU-SLK1 transcriptional corepressor of abiotic stress (e.g. salt and osmotic stress) response genes. (748 aa) |
| | Q0WKW1_ARATH | PHD finger family protein. (779 aa) |
| | HAT4 | Homeobox-leucine zipper protein HAT4; Probable transcription factor involved in the negative regulation of cell elongation and specific cell proliferation processes such as lateral root formation and secondary growth of the vascular system. Acts as mediator of the red/far-red light effects on leaf cell expansion in the shading response. Binds to the DNA sequence 5'- CAAT[GC]ATTG-3'. Negatively regulates its own expression. Belongs to the HD-ZIP homeobox family. Class II subfamily. (284 aa) |
| | CCA1 | Protein CCA1; Transcription factor involved in the circadian clock and in the phytochrome regulation. Binds to the promoter regions of APRR1/TOC1 and TCP21/CHE to repress their transcription. Binds to the promoter regions of CAB2A and CAB2B to promote their transcription. Represses both LHY and itself. (608 aa) |
| | RAV2 | AP2/ERF and B3 domain-containing transcription repressor RAV2; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional repressor of flowering time on long day plants. Acts directly on FT expression by binding 5'-CAACA-3' and 5'-CACCTG-3 sequences (Probable). Functionally redundant with TEM1. (352 aa) |
| | HAT2 | Homeobox-leucine zipper protein HAT2; Probable transcription factor that plays a role in auxin- mediated morphogenesis. Negatively regulates lateral root elongation. (283 aa) |
| | TGA2 | Transcription factor TGA2; Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as- 1 element of PR-1 promoter is salicylic acid-inducible and mediated by NPR1. Could also bind to the C-boxes (5'-ATGACGTCAT-3') with high affinity. (330 aa) |
| | PHYB | Phytochrome B; Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenetic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reduct [...] (1172 aa) |
| | OFP9 | Probable transcription repressor OFP9; Probable transcriptional repressor that may regulate multiple aspects of plant growth and development. (415 aa) |
| | ELF3 | Protein EARLY FLOWERING 3; May be a transcription factor part of a circadian clock input pathway. Acts within a 'zeitnehmer' feedback loop and is involved in its own circadian regulation. Has no role in regulating circadian clock function in the dark. Part of a corepressor complex consisting of ELF4, ELF3, and LUX involved in the transcriptional regulation of APRR9. The activity of the protein may be decreased in long day conditions due to its interaction with phytochrome B (phyB). Can regulate the initiation of flowering independently of phyB. Also involved in responses to nematode pa [...] (695 aa) |
| | GRXC12 | Putative glutaredoxin-C12; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. CC-type subfamily. (103 aa) |
| | AHL21 | AT-hook motif nuclear-localized protein 21; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). Binds to the MARs present in the ETTIN (ETT) promoter leading to a negative regulation of its gene expression. Functions as a molecular node downstream of the homeotic protein AGAMOUS (AG), regulating patterning and differentiation of reproductive organs. Acts as a chromatin remodeling factor that modifies the architecture of ETTIN (ETT) chromatin by modulating H3 methylation leading to the regulation of ETT expression. [...] (285 aa) |
| | BBX28 | B-box type zinc finger family protein. (223 aa) |
| | F8D20.120 | Zinc finger (C2H2 type) family protein. (271 aa) |
| | AS1 | Transcription factor AS1; Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis. Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development. [...] (367 aa) |
| | MRF2 | MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 2; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Belongs to the PDCD4 family. (693 aa) |
| | ERF4 | Ethylene-responsive transcription factor 4; Acts as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways, and could also regulate other AtERFs. (222 aa) |
| | MEA | Histone-lysine N-methyltransferase MEDEA; Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. Required to prevent the proliferation of the central cell of the female gametophyte by repressing target genes before fertilization. After fertilization, it probably also regulates the embryo and endosperm proliferation and anteroposterior organization during seed development. PcG proteins act by forming multiprotein complexes, which are required to maintai [...] (689 aa) |
| | JMJ15 | Lysine-specific demethylase JMJ15; Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a specific activity for H3K4me3. No activity on H3K4me2, H3K4me1, H3K9me3/2, H3K27me3/2 and H3K36me3/2. Involved in the control of flowering time by demethylating H3K4me3 at the FLC locus and repressing its expression. The repression of FLC level and reduction in H3K4me3 at the FLC locus results in induction of the flowering activator FT, which is a downstream target of FLC. (806 aa) |
| | SAP18 | Histone deacetylase complex subunit SAP18; Links the histone deacetylase complex to transcriptional repressors bound to chromatin. Involved in the tethering of the SIN3 complex to core histone proteins. (152 aa) |
| | LUH | Transcriptional corepressor LEUNIG_HOMOLOG; Transcription repressor subunit of the SEU-SLK1 and SEU-SLK2 transcriptional corepressor of abiotic stress (e.g. salt and osmotic stress) response genes, by means of an epigenetic process involving histone modification (e.g. H3K9 and H3K14 acetylation), probably by recruiting HDAC, to facilitate the condensation of chromatin thus preventing transcription at the target genes. Can also act as a transcription activator. Implicated in embryo and floral development. Involved in post- synthesis cell wall modifications necessary for mucilage extrusi [...] (787 aa) |
| | F3I6.18 | Paired amphipathic helix (PAH2) superfamily protein. (252 aa) |
| | F3I6.15 | Paired amphipathic helix repeat-containing protein. (744 aa) |
| | SNL3 | Paired amphipathic helix protein Sin3-like 3; Acts as a transcriptional repressor. Interacts with ERF7 to repress genes in abscisic acid and drought stress responses. The heterodimer represses transcription by tethering SNL3 to DNA. (1330 aa) |
| | AN | C-terminal binding protein AN; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Required for cortical microtubules (MTs) arrangement that confers cell shape. Regulates the width of leaves by controlling the polar elongation of leaf cells. Involved in the regulation of trichome branching. Seems to not be able to regulate gene transcription. Regulates epidermal cell divisions and elongation in a non-cell-autonomous manner (regulated by subepidermal cells), but regulates epidermal cell polarity, shape, trichome branching [...] (636 aa) |
| | H2AV | Histone H2A variant 1; Variant histone H2A which may replace conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa) |
| | GRXS5 | Monothiol glutaredoxin-S5; May only reduce GSH-thiol disulfides, but not protein disulfides; Belongs to the glutaredoxin family. CC-type subfamily. (102 aa) |
| | OFP11 | Transcription repressor OFP11; Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (182 aa) |
| | CDF4 | Cyclic dof factor 4; Transcription factor that binds specifically to a 5'-AA[AG]G- 3' consensus core sequence (By similarity). Transcriptional repressor of 'CONSTANS' expression (By similarity). Regulates a photoperiodic flowering response. (170 aa) |
| | RZ1B | Glycine-rich RNA-binding protein RZ1B; Binds RNA and DNA sequences non-specifically. May be involved in tolerance to cold stress. (292 aa) |
| | HDA19 | Histone deacetylase 19; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDA19 is involved in jasmonic acid and ethylene signaling of pathogen response. Part of a repressor complex including APETALA2 (AP2) and TOPLESS (TPL) that control the expression domains of numerous flora [...] (501 aa) |
| | F17L21.4 | Paired amphipathic helix (PAH2) superfamily protein. (137 aa) |
| | F17L21.3 | Paired amphipathic helix (PAH2) superfamily protein. (186 aa) |
| | SNL4 | Paired amphipathic helix protein Sin3-like 4; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1326 aa) |
| | OFP2 | Transcription repressor OFP2; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (320 aa) |
| | ELF4 | Protein EARLY FLOWERING 4; Component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles. Part of a corepressor complex consisting of ELF4, ELF3, and LUX involved in the transcriptional regulation of APRR9. Increases ELF3 nuclear distribution and localization in nuclear bodies. Required for responsiveness to continuous red, by regulating phytochrome B (phyB) signaling (including during seedling de-etiolation) and gene expression. Mediates both entrainment to an env [...] (111 aa) |
| | ET2 | Protein EFFECTOR OF TRANSCRIPTION 2; Transcriptional regulator involved in the regulation of cell differentiation in meristems. Probably regulates the expression of various KNAT genes involved in the maintenance of the cells in an undifferentiated, merismastic state. Plays a role in the regulation of gibberellin 20 oxidase and the gibberellin-regulated protein GASA4. Localizes in the nucleus during the cellular differentiation state and may act via a single strand cutting domain. Transcriptional regulator required for the induction of dormancy during late seed development. Interacts ge [...] (483 aa) |
| | F2G14.150 | Paired amphipathic helix Sin3-like protein. (139 aa) |
| | F24C7.4 | RING/FYVE/PHD zinc finger superfamily protein. (1193 aa) |
| | SLK3 | Probable transcriptional regulator SLK3; Probable transcription regulator that functions in the development of the carpel margin meristem similarly to SEUSS (SEU). In association with SEU, supports organ development from meristematic regions by facilitating auxin response and thus organ initiation, and by sustaining meristematic potential through the maintenance of PHABULOSA expression (By similarity). (685 aa) |
| | SRFR1 | Suppressor of RPS4-RLD 1; Negative regulator of effector-triggered immunity associated with the EDS1 resistance pathway. May localize its interactors to a microsomal membrane. May therefore negatively regulate RPS4 and SNC1 translocation to the nucleus. Contributes to the regulation of RPS2 and RPS4 protein levels and negatively regulates SNC1 stability. (1052 aa) |
| | NTL9 | Protein NTM1-like 9; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites. Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene. Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression [...] (512 aa) |
| | F4JKT1_ARATH | Histone deacetylase. (70 aa) |
| | NDX | Nodulin homeobox; Regulates COOLAIR, a set of antisense transcripts originating from the 3' end of FLOWERING LOCUS C (FLC). Associates with single- stranded DNA that is part of an RNA-DNA hybrid, or R-loop, that covers the COOLAIR promoter. R-loop stabilization mediated by NDX inhibits COOLAIR transcription, which in turn modifies FLC expression. (913 aa) |
| | F4J6V1_ARATH | Duplicated homeodomain-like superfamily protein. (1656 aa) |
| | F4J5R1_ARATH | RING/FYVE/PHD-type zinc finger family protein. (696 aa) |
| | T12J13.15 | Signal transducer, putative (DUF3550/UPF0682). (607 aa) |
| | F4J0F5_ARATH | Paired amphipathic helix SIN3-like protein. (355 aa) |
| | JAZ13 | Protein JAZ13; Non-TIFY functional repressor of jasmonate (JA)-mediated growth and defense responses. Intrinsically resistant to JA-induced turnover, probably due to the absence of the canonical degron that strongly interacts with COI1 in the presence of JA-Ile in the TIFY/JAZ proteins. (125 aa) |
| | F27F23.6 | RING/FYVE/PHD zinc finger superfamily protein. (631 aa) |
| | SPEAR2 | Protein SPEAR2; Adapter-like transcriptional repressor recruiting TPL/TPR corepressors to inhibit TCP transcription factors (By similarity). May be involved in leaf development. (300 aa) |
| | F3I6.13 | Paired amphipathic helix (PAH2) superfamily protein. (196 aa) |
| | OFP12 | Transcription repressor OFP12; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (226 aa) |
| | BARD1 | BRCA1-associated RING domain protein 1; Binds specifically to H3K4me3 regions of target genes (e.g. WUS and WOX5) promoters to repress their transcription via chromatin remodeling. Required for the shoot apical meristem (SAM) organization and maintenance, by confining WUS expression to the organizing center, and for the quiescent center (QC) development in the root apical meristem (RAM), by repressing WOX5 expression in the root proximal meristem. Plays a role in DNA repair and in cell-cycle control. Required for the repair of DNA double-strand breaks (DSBs), both natural and induced b [...] (714 aa) |
| | F7G19.9 | Arginine-glutamic acid dipeptide repeat protein. (911 aa) |
| | T7N22.1 | Uncharacterized protein. (915 aa) |
| | RLT1 | Homeobox-DDT domain protein RLT1; Transcriptional regulator required for the maintenance of the plant vegetative phase. In association with CHR11 or CHR17 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. (1705 aa) |
| | F17L21.6 | Paired amphipathic helix (PAH2) superfamily protein. (225 aa) |
| | F17L21.32 | Paired amphipathic helix (PAH2) superfamily protein. (222 aa) |
| | OFP4 | Transcription repressor OFP4; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. Forms a transcription repression complex with KNAT7 which regulates secondary cell wall formation. (315 aa) |
| | B3H6R4_ARATH | Ovate family protein. (183 aa) |
| | TCL2 | MYB-like transcription factor TCL2; MYB-type transcription factor involved in trichome cell specification. Acts as a negative regulator of trichome patterning and formation. May function by suppressing the expression of GL3. (100 aa) |
| | F3I6.16 | Paired amphipathic helix (PAH2) superfamily protein. (245 aa) |
| | A0A1P8BFD5 | Paired amphipathic helix Sin3-like protein. (122 aa) |
| | T31B5.60 | Repressor of RNA polymerase III transcription. (244 aa) |
| | A0A1P8B3X9 | Transcription repressor. (176 aa) |
| | A0A1I9LNF2 | Nuclear transport factor 2/RNA recognition motif protein. (293 aa) |
