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PGL1-2 PGL1-2 NADP-ME2 NADP-ME2 TRA2 TRA2 RPI3 RPI3 PGIC PGIC HXK2 HXK2 HXK1 HXK1 G6PD1 G6PD1 PGL3-2 PGL3-2 G6PD3 G6PD3 PGL5 PGL5 PGL2-2 PGL2-2 TKL-1 TKL-1 F28J7.18 F28J7.18 F9N12.9 F9N12.9 RPI1 RPI1 A0A1P8ARU2 A0A1P8ARU2 T28K15.4 T28K15.4 TKL-2 TKL-2 RPI2 RPI2 PGD1 PGD1 RPE RPE PGD3 PGD3 RPI4 RPI4 PGL4 PGL4 PGD2 PGD2 PGI1 PGI1 G6PD6 G6PD6 HXK3 HXK3 G6PD5 G6PD5 G6PD2 G6PD2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PGL1-2Probable 6-phosphogluconolactonase 1; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (268 aa)
NADP-ME2NADP-dependent malic enzyme 2. (588 aa)
TRA2Aldolase-type TIM barrel family protein. (438 aa)
RPI3Probable ribose-5-phosphate isomerase 3, chloroplastic; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (276 aa)
PGICGlucose-6-phosphate isomerase, cytosolic; Belongs to the GPI family. (560 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
G6PD1Glucose-6-phosphate 1-dehydrogenase 1, chloroplastic; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division. Belongs to the glucose-6-phosphate dehydrogenase family. (576 aa)
PGL3-26-phosphogluconolactonase 3, chloroplastic; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. Involved in the regulation of cellular redox state; enzymatic activity is required for this function. Required for sugar-dependent expression of nitrate assimilation genes in the nucleus of root cells. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (325 aa)
G6PD3Glucose-6-phosphate 1-dehydrogenase 3, chloroplastic; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division. (599 aa)
PGL5Probable 6-phosphogluconolactonase 5; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (252 aa)
PGL2-2Probable 6-phosphogluconolactonase 2; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (259 aa)
TKL-1Transketolase-1, chloroplastic; Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose- 4-phosphate or ribose-5-phosphate, respectively (By similarity). Could act as a stress sensor involved in adaptation process. (741 aa)
F28J7.18Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
F9N12.9Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
RPI1Probable ribose-5-phosphate isomerase 1; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (267 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
T28K15.4Aldolase superfamily protein. (427 aa)
TKL-2Transketolase-2, chloroplastic; Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose- 4-phosphate or ribose-5-phosphate, respectively (By similarity). Could act as a stress sensor involved in adaptation process; Belongs to the transketolase family. (741 aa)
RPI2Probable ribose-5-phosphate isomerase 2; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (265 aa)
PGD16-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (487 aa)
RPERibulose-5-phosphate-3-epimerase, chloroplastic; Essential protein required during embryogenesis. Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate (By similarity). Essential for the early steps of nematode feeding sites (NFS, multinucleated root cells) formation induced by the root-knot nematodes Heterodera schachtii, Meloidogyne incognita, M.javanica and M.hapla ; Belongs to the ribulose-phosphate 3-epimerase family. (281 aa)
PGD36-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (487 aa)
RPI4Probable ribose-5-phosphate isomerase 4, chloroplastic; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (296 aa)
PGL4Probable 6-phosphogluconolactonase 4; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (261 aa)
PGD26-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. Required for guided growth of the male gametophytes and interaction between the pollen tube and the ovule. (486 aa)
PGI1Glucose-6-phosphate isomerase 1, chloroplastic; Promotes the synthesis of starch in leaves. (613 aa)
G6PD6Glucose-6-phosphate 1-dehydrogenase 6, cytoplasmic; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division. (515 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
G6PD5Glucose-6-phosphate 1-dehydrogenase 5, cytoplasmic; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division. (516 aa)
G6PD2Glucose-6-phosphate 1-dehydrogenase 2, chloroplastic; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division. Belongs to the glucose-6-phosphate dehydrogenase family. (596 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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