STRINGSTRING
A0A1I9LLJ3 A0A1I9LLJ3 F5M15.11 F5M15.11 SMG7 SMG7 TPX2 TPX2 AtWAPL1 AtWAPL1 KIN5A KIN5A AUG1 AUG1 QWRF4 QWRF4 F23N11.13 F23N11.13 KIN12E KIN12E KIN14D KIN14D QWRF9 QWRF9 T28J14.110 T28J14.110 F4K773_ARATH F4K773_ARATH T20K14.120 T20K14.120 AUG2 AUG2 EDE1 EDE1 KIN14M KIN14M KIN14N KIN14N KIN5C KIN5C KIN14C KIN14C emb1427 emb1427 AUG3 AUG3 KIN5B KIN5B AUG7 AUG7 QWRF7 QWRF7 F16J13.60 F16J13.60 F7H19.40 F7H19.40 QWRF6 QWRF6 MMI9.7 MMI9.7 TEL3N.1 TEL3N.1 EB1A EB1A SCO3 SCO3 AUG4 AUG4 QWRF3 QWRF3 QWRF2 QWRF2 AUG6 AUG6 GCP2-2 GCP2-2 AtWAPL2 AtWAPL2 GIP2 GIP2 GCP3 GCP3 EB1C EB1C EB1B EB1B K9L2.2 K9L2.2 AUG5 AUG5 KIN5D KIN5D GIP1-2 GIP1-2 GCP4 GCP4 F7D8.30 F7D8.30 AUG8 AUG8
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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A0A1I9LLJ3Spc97 / Spc98 family of spindle pole body (SBP) component. (1208 aa)
F5M15.11Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (985 aa)
SMG7Protein SMG7; Plays multiple roles in growth and development. Involved in nonsense-mediated mRNA decay (NMD). May provide a link to the mRNA degradation machinery to initiate NMD and serve as an adapter for UPF proteins function. Required for meiotic progression through anaphase II of pollen mother cells. May counteract cyclin-dependent kinase (CDK) activity at the end of meiosis. May play a role in plant defense through its involvement in NMD. Together with EXA1, helps to restrict cell death induction during pathogen infection in a salicylic acid- (SA) and reactive oxygen species- (RO [...] (1059 aa)
TPX2Protein TPX2; Regulates prospindle assembly during late prophase and at the onset of mitosis, before nuclear envelope breakdown (NEB). Is exported from the nucleus shortly before NEB and organized into two polar crescents. After NEB, is progressively associated with the forming spindle. Probably mediates AUR1 activation and localization to spindle microtubules. Has a microtubule binding capability and is able to trigger microtubule assembly induced by RanGTP in a heterologous system. Not involved in phragmoplast assembly, nuclear envelope reformation, and cortical microtubule assembly [...] (790 aa)
AtWAPL1WAPL (Wings apart-like protein regulation of heterochromatin) protein. (930 aa)
KIN5AKinesin-like protein KIN-5A; Responsible for microtubule translocation. May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity). Plays an essential role in stabilizing the mitotic spindle. Required during mitotic cytokinesis. (1042 aa)
AUG1AUGMIN subunit 1; Involved in microtubules reorganization during spindle and phragmoplast development. (299 aa)
QWRF4QWRF motif-containing protein 4; Belongs to the QWRF family. (609 aa)
F23N11.13QWRF motif protein (DUF566). (211 aa)
KIN12EKinesin-like protein KIN-12E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily. (1263 aa)
KIN14DKinesin-like protein KIN-14D; Kinesin that supports microtubule movement in an ATP- dependent manner and that functions as a minus-end directed motor as well as a plus-end tracking protein. During mitosis, is involved in early spindle assembly. Participates in the capture of antiparallel interpolar microtubules and helps in generating force to coalign microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily. (790 aa)
QWRF9QWRF motif-containing protein 9; Belongs to the QWRF family. (513 aa)
T28J14.110Cell cycle regulated microtubule associated protein. (363 aa)
F4K773_ARATHTPX2 (Targeting protein for Xklp2) protein family. (178 aa)
T20K14.120TPX2 (Targeting protein for Xklp2) protein family. (519 aa)
AUG2AUGMIN subunit 2; Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex. (296 aa)
EDE1Protein ENDOSPERM DEFECTIVE 1; Microtubule-associated protein required for seed development and for microtubule function in the endosperm. Associates with nuclear microtubules during mitosis. Binds to microtubules of the spindle and spindle-poles and to midzone microtubules out of which the phragmoplast emerges. Not associated with cortical microtubules. Required for endosperm cellularization. May be bound and sequestered by GRF5 in an inactive soluble form during the early stages of mitosis. (474 aa)
KIN14MKinesin-like protein KIN-14M. (745 aa)
KIN14NKinesin-like protein KIN-14N. (754 aa)
KIN5CKinesin-like protein KIN-5C; Responsible for microtubule translocation. May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity). Plays an essential role in stabilizing the mitotic spindle. Required during mitotic cytokinesis (By similarity). (1009 aa)
KIN14CKinesin-like protein KIN-14C; Kinesin that supports microtubule movement in an ATP- dependent manner and has a minus-end directed polarity. Plays a crucial role in spindle morphogenesis in male meiosis. In mitosis, is required for normal microtubule accumulation at the spindle poles during prophase and may play a role in spindle assembly during prometaphase. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily. (793 aa)
emb1427Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (995 aa)
AUG3AUGMIN subunit 3; Involved in microtubules reorganization during spindle and phragmoplast development. Required for gamma-tubulin localization during mitosis; Belongs to the HAUS3 family. (617 aa)
KIN5BKinesin-like protein KIN-5B; Responsible for microtubule translocation. May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity). Plays an essential role in stabilizing the mitotic spindle. Required during mitotic cytokinesis (By similarity). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily. (1039 aa)
AUG7AUGMIN subunit 7; Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex. Regulates the association of gamma-tubulin with the spindle and phragmoplast microtubules. (329 aa)
QWRF7QWRF motif-containing protein 7. (394 aa)
F16J13.60Cell cycle regulated microtubule associated protein. (501 aa)
F7H19.40Cell cycle regulated microtubule associated protein. (509 aa)
QWRF6QWRF motif-containing protein 6. (442 aa)
MMI9.7Cell cycle regulated microtubule associated protein. (377 aa)
TEL3N.1TPX2 (Targeting protein for Xklp2) protein family. (488 aa)
EB1AMicrotubule-associated protein RP/EB family member 1A; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. May be involved in anchoring microtubules to their nucleation sites and/or functioning as a reservoir for distribution to the growing end. In plants, microtubule minus ends are not necessarily severed from the nucleation site and transported to the plus end of a microtubule as part of the recycling process. May play a role in endomembrane organization during polarized growth of plant cells. Interacts with the tobamovirus movement prote [...] (276 aa)
SCO3Protein SNOWY COTYLEDON 3; Probable microtubule-associated peroxisomal protein required for chloroplast biogenesis and for the formation of the prolamellar body and prothylakoids in etioplasts. Not involved in peroxisomal metabolism, including mobilization of storage compounds during germination, fatty acid beta-oxydation or photorespiration; Belongs to the QWRF family. (644 aa)
AUG4AUGMIN subunit 4; Involved in microtubules reorganization during spindle and phragmoplast development; Belongs to the HAUS4 family. (423 aa)
QWRF3QWRF motif-containing protein 3. (482 aa)
QWRF2QWRF motif-containing protein 2; Belongs to the QWRF family. (659 aa)
AUG6AUGMIN subunit 6; Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex. (741 aa)
GCP2-2Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the microtubule organizing centers (MTOCs). Required for the positioning of the gamma-tubulin-containing complex on pre-existing microtubules and for the proper organization of cortical arrays. (678 aa)
AtWAPL2WAPL (Wings apart-like protein regulation of heterochromatin) protein. (840 aa)
GIP2Mitotic-spindle organizing protein 1A; Required for gamma-tubulin complex recruitment to the microtubule organizing centers (MTOCs) (By similarity). During mitosis, modulates gamma-tubulin complex localization, spindle stability and chromosomal segregation. Necessary for gametophyte development and embryogenesis. (67 aa)
GCP3Gamma-tubulin complex component 3; Gamma-tubulin complex is necessary for microtubule nucleation at the microtubule organizing centers (MTOCs). Required for the positioning of the gamma-tubulin-containing complex on pre-existing microtubules and for the proper organization of cortical arrays. (838 aa)
EB1CMicrotubule-associated protein RP/EB family member 1C; Plant-specific EB1 subtype that functions preferentially at early stages of plant mitosis by regulating spindle positioning and chromosome segregation. Accumulates in the prophase nucleus and is required to maintain spindle bipolarity during premetaphase and/or metaphase and for efficient segregation of chromosomes at anaphase. May play a role in the dynamics of microtubule network in elongating pollen tubes. (329 aa)
EB1BMicrotubule-associated protein RP/EB family member 1B; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. May be involved in anchoring microtubules to their nucleation sites and/or functioning as a reservoir for distribution to the growing end. In plants, microtubule minus ends are not necessarily severed from the nucleation site and transported to the plus end of a microtubule as part of the recycling process. May play a role in endomembrane organization during polarized growth of plant cells. (293 aa)
K9L2.2TPX2 (Targeting protein for Xklp2) protein family. (309 aa)
AUG5AUGMIN subunit 5; Involved in microtubules reorganization during spindle and phragmoplast development; Belongs to the HAUS5 family. (796 aa)
KIN5DKinesin-like protein KIN-5D; Responsible for microtubule translocation. May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity). Plays an essential role in stabilizing the mitotic spindle. Required during mitotic cytokinesis (By similarity). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily. (1058 aa)
GIP1-2Mitotic-spindle organizing protein 1B; Required for gamma-tubulin complex recruitment to the microtubule organizing centers (MTOCs) (By similarity). During mitosis, modulates gamma-tubulin complex localization, spindle stability and chromosomal segregation. Necessary for gametophyte development and embryogenesis; Belongs to the MOZART1 family. (71 aa)
GCP4Gamma-tubulin complex component 4; Gamma-tubulin complex is necessary for microtubule nucleation at the microtubule organizing centers (MTOCs). (745 aa)
F7D8.30HAUS augmin-like complex subunit. (59 aa)
AUG8AUGMIN subunit 8; Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex. Microtubule plus-end binding protein promoting tubulin polymerization and microtubule reorientation in hypocotyls. Promotes microtubule branching. Plays an important role in modulating hypocotyl growth. (644 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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