STRINGSTRING
SUD1 SUD1 PP2A2-2 PP2A2-2 MYB115 MYB115 LIL3.2 LIL3.2 VIP1 VIP1 MED15A MED15A DOF2.5 DOF2.5 LIL3.1 LIL3.1 NFYB9 NFYB9 MYB92 MYB92 FUS3 FUS3 MYB118 MYB118 TOR TOR SRM1 SRM1 TSN2 TSN2 WAT1 WAT1 ADAP ADAP TSN1 TSN1 MKK5 MKK5 CLE25 CLE25 B'THETA B'THETA NHL6 NHL6 VIP2-2 VIP2-2 NAC047 NAC047 T19B17.4 T19B17.4
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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SUD1Probable E3 ubiquitin ligase SUD1; Probable E3 ubiquitin ligase acting as a positive post- transcriptional regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity. Might be involved in the quality control that degrades misfolded proteins (By similarity). (1108 aa)
PP2A2-2Serine/threonine-protein phosphatase PP2A-2 catalytic subunit; Dephosphorylates and activates the actin-depolymerizing factor ADF1, which, in turn, regulates actin cytoskeleton remodeling and is involved in the blue light photoreceptor PHOT2-mediated chloroplast avoidance movements. Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Acts as negative regulator of abscisic acid (ABA) signaling. May r [...] (306 aa)
MYB115Transcription factor MYB115; Transcription activator that recognizes the motif 5'-TAACGG- 3' in the promoter of target genes. Promotes vegetative-to-embryonic transition and the formation of somatic embryos from root explants in a WUS-independent manner. Together with MYB118, activates the transcription of S-ACP-DES2/AAD2 and S-ACP-DES3/AAD3 thus promoting the biosynthesis of omega-7 monounsaturated fatty acid in seed endosperm. (359 aa)
LIL3.2Light-harvesting complex-like protein 3 isotype 2, chloroplastic; Light-harvesting-like protein required for biosynthesis of phytylated chlorophylls and alpha-tocopherol in green seedlings. Functions by anchoring geranylgeranyl reductase (GGR) in the thylakoid membrane, leading to the stabilization of GGR activity. Binds chlrophyll a in the thylakoid membrane. Plays a role in the regulation of chlorophyll biosynthesis under light stress and under standard growth conditions. (258 aa)
VIP1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase VIP1; Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis- diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2- InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 [...] (1050 aa)
MED15AMediator of RNA polymerase II transcription subunit 15a; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general [...] (1335 aa)
DOF2.5Dof zinc finger protein DOF2.5; Transcription factor specifically involved in the maternal control of seed germination. Regulates transcription by binding to a 5'-AA[AG]G-3' consensus core sequence. May ensure the activation of a component that would trigger germination as a consequence of red light perception. (369 aa)
LIL3.1Light-harvesting complex-like protein 3 isotype 1, chloroplastic; Light-harvesting-like protein required for biosynthesis of phytylated chlorophylls and alpha-tocopherol in green seedlings. Functions by anchoring geranylgeranyl reductase (GGR) in the thylakoid membrane, leading to the stabilization of GGR activity. Binds chlrophyll a in the thylakoid membrane (By similarity). Plays a role in the regulation of chlorophyll biosynthesis under light stress and under standard growth conditions. (262 aa)
NFYB9Nuclear transcription factor Y subunit B-9; Component of the NF-Y/HAP transcription factor complex. The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters. Acts as a central regulator of the embryogenesis. Required for the speciation of cotyledon identity and the completion of embryo maturation. Controls seed storage protein genes through the regulation of FUS3 and ABI3. Involved in the blue light (BL) and abscisic acid (ABA) signaling pathways; Belongs to the NFYB/HAP3 subunit family. (238 aa)
MYB92Transcription factor MYB92; Probable transcription factor. (334 aa)
FUS3B3 domain-containing transcription factor FUS3; Transcription regulator involved in gene regulation during late embryogenesis. Its expression to the epidermis is sufficient to control foliar organ identity by regulating positively the synthesis abscisic acid (ABA) and negatively gibberellin production. Negatively regulates TTG1 in the embryo. Positively regulates the abundance of the ABI3 protein in the seed. Cooperates with KIN10 to regulate developmental phase transitions and lateral organ development and act both as positive regulators of abscisic acid (ABA) signaling during germination. (313 aa)
MYB118Transcription factor MYB118; Transcription activator that recognizes the motif 5'-TAACGG- 3' in the promoter of endosperm-induced genes. Promotes vegetative-to-embryonic transition and the formation of somatic embryos from root explants in a WUS-independent manner but via the expression of embryonic genes (e.g. LEC1, LEC2, FUS3 and WUS). May play an important role during embryogenesis and seed maturation. Together with MYB115, activates the transcription of S-ACP-DES2/AAD2 and S-ACP-DES3/AAD3 thus promoting the biosynthesis of omega-7 monounsaturated fatty acid in seed endosperm. Regul [...] (437 aa)
TORSerine/threonine-protein kinase TOR; Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival. Involved in modulating the transition from heterotrophic [...] (2481 aa)
SRM1Transcription factor SRM1; Transcription activator that coordinates abscisic acid (ABA) biosynthesis and signaling-related genes via binding to the specific promoter motif 5'-(A/T)AACCAT-3'. Represses ABA-mediated salt (e.g. NaCl and KCl) stress tolerance. Regulates leaf shape and promotes vegetative growth. (298 aa)
TSN2Ribonuclease TUDOR 2; Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress. Essential for the integrity and function of cytoplasmic messenger ribonucleoprotein (mRNP) complexes called stress granules (SGs) and processing bodies (PBs), sites of post-transcriptional gene regulation during stress (e.g. salt and heat). Involved in gibberellic acid (GA) biosynthesis and seed germination. Essential for stress tolerance, probably by regulating mRNAs entering the secretory pathway. Component of stress gr [...] (985 aa)
WAT1Protein WALLS ARE THIN 1; Required for secondary wall formation in fibers, especially in short days conditions. Promotes indole metabolism and transport (e.g. tryptophan, neoglucobrassicin and auxin (indole-3-acetic acid)). May prevent salicylic-acid (SA) accumulation. Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family. (389 aa)
ADAPAP2-like ethylene-responsive transcription factor At1g16060; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). (345 aa)
TSN1Ribonuclease TUDOR 1; Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress. Essential for the integrity and function of cytoplasmic messenger ribonucleoprotein (mRNP) complexes called stress granules (SGs) and processing bodies (PBs), sites of post-transcriptional gene regulation during stress (e.g. salt and heat). Involved in gibberellic acid (GA) biosynthesis. Essential for stress tolerance, probably by regulating mRNAs entering the secretory pathway. Component of stress granules (SGs) that reg [...] (991 aa)
MKK5Mitogen-activated protein kinase kinase 5; Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the [...] (348 aa)
CLE25CLAVATA3/ESR (CLE)-related protein 25; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Belongs to the CLV3/ESR signal peptide family. (81 aa)
B'THETASerine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Associates with the serine/threonine-protein phosphatase PP2A catalytic subunit C and regulatory subunit A to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Required for the formation of the PP2A holoenzym [...] (492 aa)
NHL6NDR1/HIN1-like protein 6; Plays an important role in the abiotic stresses-induced abscisic acid (ABA) signaling and biosynthesis. Acts as positive regulator of ABA-mediated seed germination inhibition. Functions downstream of ABF2/AREB1, ABF4/AREB2 and ABF3. (252 aa)
VIP2-2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase VIP2; Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis- diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2- InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 [...] (1049 aa)
NAC047NAC transcription factor 47; Transcription factor that binds to the promoter of ACO5, an ACC oxidase involved in ethylene biosynthesis. Mediates waterlogging- induced hyponastic leaf movement, and cell expansion in abaxial cells of the basal petiole region, by directly regulating the expression of ACO5. Required for normal seed development and morphology. (359 aa)
T19B17.4Malonyl-CoA decarboxylase family protein. (518 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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