(31 nodes) Adenylyltransferase activity network (Arabidopsis thaliana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APL3	Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (521 aa)
	T22J18.17	Polynucleotide adenylyltransferase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (610 aa)
	APS2	Inactive glucose-1-phosphate adenylyltransferase small subunit 2, chloroplastic; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (476 aa)
	MEE44	Nucleotidyltransferase family protein. (1481 aa)
	NMNAT	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate. Belongs to the eukaryotic NMN adenylyltransferase family. (238 aa)
	T22P11.260	Uncharacterized protein. (372 aa)
	FHIT	Bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT; Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. In addition, possesses adenylylsulfatase and nucleoside phosphoramidase activities. Liberates AMP from natural metabolites such as 5'-adenylyl sulfate and adenosine 5'-phosphoramidate. Recognizes synthetic nucleotides, such as adenosine 5'-O-phosphorofluoridate and adenosine 5'-O-(gamma-fluorotriphosphate), and releases AMP from them. (180 aa)
	APS3	ATP-sulfurylase 3, chloroplastic. (465 aa)
	PAPS2	Nuclear poly(A) polymerase 2; Essential protein. Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity). Mediates the polyadenylation of RNAs that are associated with polynucleotide phosphorylase (e.g. PNP1). (800 aa)
	APS1	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (520 aa)
	ADG2	Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (522 aa)
	APL2	Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (518 aa)
	CNX1-2	Molybdopterin biosynthesis protein CNX1; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released; In the N-terminal section; belongs to the MoaB/Mog family. (670 aa)
	APS2-2	ATP sulfurylase 2; Belongs to the sulfate adenylyltransferase family. (476 aa)
	PAPS3	Nuclear poly(A) polymerase 3; Essential protein. Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity). (507 aa)
	FHY	Bifunctional riboflavin kinase/FMN phosphatase; Bifunctional enzyme that catalyzes the hydrolysis of flavin- mononucleotide (FMN) to riboflavin (vitamin B2) and the phosphorylation of riboflavin to form (FMN) coenzyme; In the C-terminal section; belongs to the flavokinase family. (379 aa)
	Q84Q59_ARATH	Nucleotidylyl transferase superfamily protein. (389 aa)
	HINT4	Bifunctional adenosine 5'-phosphosulfate phosphorylase/adenylylsulfatase HINT4; Possesses adenylylsulfatase activity in vitro, releasing AMP and sulfate from adenylyl sulfate. Possesses also adenosine 5'- phosphosulfate (APS) phosphorylase activity in vitro. Catalyzes the phosphorolysis of APS, leading to ADP and sulfate. (146 aa)
	MGN6.13	Nucleotidyltransferase family protein. (530 aa)
	F10A8.10	Nucleotidylyl transferase superfamily protein. (388 aa)
	PAPS4	Nuclear poly(A) polymerase 4; Essential protein. Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity). (741 aa)
	RIBF2	FAD synthetase 2, chloroplastic; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. (367 aa)
	MRG7.16	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity. (351 aa)
	RIBF1	FAD synthetase 1, chloroplastic; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. (354 aa)
	APS1-2	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family. (463 aa)
	PAPS1	Nuclear poly(A) polymerase 1; Essential protein. Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity). (713 aa)
	F12E4.190	Phosphoadenosine phosphosulfate (PAPS) reductase family protein. (497 aa)
	APS4	ATP sulfurylase 4, chloroplastic. (469 aa)
	APL4	Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP (By similarity); Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (523 aa)
	MOCS3	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (464 aa)
	COAD	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Does not accept 4'-phosphopantothenoylcysteine as a substrate. (176 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADG2	APS1	P55229	P55228	Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.444
ADG2	MRG7.16	P55229	Q9FK51	Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity.	0.454
APL2	APS1	P55230	P55228	Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.403
APL2	MRG7.16	P55230	Q9FK51	Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity.	0.456
APL3	MRG7.16	P55231	Q9FK51	Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity.	0.562
APL4	APS1	Q9SIK1	P55228	Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP (By similarity); Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.514
APL4	MRG7.16	Q9SIK1	Q9FK51	Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP (By similarity); Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity.	0.455
APS1	ADG2	P55228	P55229	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.444
APS1	APL2	P55228	P55230	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	0.403
APS1	APL4	P55228	Q9SIK1	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP (By similarity); Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	0.514
APS1	MRG7.16	P55228	Q9FK51	Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity.	0.562
APS1-2	APS2-2	Q9LIK9	Q43870	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family.	ATP sulfurylase 2; Belongs to the sulfate adenylyltransferase family.	0.903
APS1-2	APS3	Q9LIK9	O23324	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family.	ATP-sulfurylase 3, chloroplastic.	0.938
APS1-2	APS4	Q9LIK9	Q9S7D8	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family.	ATP sulfurylase 4, chloroplastic.	0.902
APS1-2	F12E4.190	Q9LIK9	Q9LZE4	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family.	Phosphoadenosine phosphosulfate (PAPS) reductase family protein.	0.811
APS1-2	HINT4	Q9LIK9	Q84VV6	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family.	Bifunctional adenosine 5'-phosphosulfate phosphorylase/adenylylsulfatase HINT4; Possesses adenylylsulfatase activity in vitro, releasing AMP and sulfate from adenylyl sulfate. Possesses also adenosine 5'- phosphosulfate (APS) phosphorylase activity in vitro. Catalyzes the phosphorolysis of APS, leading to ADP and sulfate.	0.955
APS2	MRG7.16	F4I8U2	Q9FK51	Inactive glucose-1-phosphate adenylyltransferase small subunit 2, chloroplastic; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.	ADP-glucose phosphorylase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity.	0.417
APS2-2	APS1-2	Q43870	Q9LIK9	ATP sulfurylase 2; Belongs to the sulfate adenylyltransferase family.	ATP sulfurylase 1, chloroplastic; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation; Belongs to the sulfate adenylyltransferase family.	0.903
APS2-2	APS3	Q43870	O23324	ATP sulfurylase 2; Belongs to the sulfate adenylyltransferase family.	ATP-sulfurylase 3, chloroplastic.	0.903
APS2-2	APS4	Q43870	Q9S7D8	ATP sulfurylase 2; Belongs to the sulfate adenylyltransferase family.	ATP sulfurylase 4, chloroplastic.	0.903