(11 nodes) Guanylyltransferase activity network (Arabidopsis thaliana)

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	THG2	tRNA(His) guanylyltransferase 2; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (537 aa)
	F26C17.2	mRNA capping enzyme family protein. (625 aa)
	T22E16.250	Probable mannose-1-phosphate guanylyltransferase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. (364 aa)
	FKGP	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP. (1055 aa)
	VTC5	GDP-L-galactose phosphorylase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor. (431 aa)
	VTC2	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor. (442 aa)
	F17I23.90	Probable mannose-1-phosphate guanylyltransferase 3; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. (331 aa)
	T10O8.2	mRNA capping enzyme family protein. (657 aa)
	CYT1	Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate. (361 aa)
	THG1	tRNA(His) guanylyltransferase 1; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (567 aa)
	F4IYM6_ARATH	mRNA capping enzyme family protein. (672 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYT1	FKGP	O22287	Q9LNJ9	Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate.	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP.	0.605
CYT1	VTC2	O22287	Q8RWE8	Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate.	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	0.955
CYT1	VTC5	O22287	Q9FLP9	Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate.	GDP-L-galactose phosphorylase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	0.914
F17I23.90	FKGP	Q8H1Q7	Q9LNJ9	Probable mannose-1-phosphate guanylyltransferase 3; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP.	0.695
F17I23.90	VTC2	Q8H1Q7	Q8RWE8	Probable mannose-1-phosphate guanylyltransferase 3; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	0.405
F26C17.2	F4IYM6_ARATH	Q9S9L3	F4IYM6	mRNA capping enzyme family protein.	mRNA capping enzyme family protein.	0.906
F26C17.2	T10O8.2	Q9S9L3	Q8GSD7	mRNA capping enzyme family protein.	mRNA capping enzyme family protein.	0.905
F4IYM6_ARATH	F26C17.2	F4IYM6	Q9S9L3	mRNA capping enzyme family protein.	mRNA capping enzyme family protein.	0.906
F4IYM6_ARATH	T10O8.2	F4IYM6	Q8GSD7	mRNA capping enzyme family protein.	mRNA capping enzyme family protein.	0.903
FKGP	CYT1	Q9LNJ9	O22287	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP.	Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate.	0.605
FKGP	F17I23.90	Q9LNJ9	Q8H1Q7	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP.	Probable mannose-1-phosphate guanylyltransferase 3; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	0.695
FKGP	T22E16.250	Q9LNJ9	Q9M2S0	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP.	Probable mannose-1-phosphate guanylyltransferase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	0.698
T10O8.2	F26C17.2	Q8GSD7	Q9S9L3	mRNA capping enzyme family protein.	mRNA capping enzyme family protein.	0.905
T10O8.2	F4IYM6_ARATH	Q8GSD7	F4IYM6	mRNA capping enzyme family protein.	mRNA capping enzyme family protein.	0.903
T22E16.250	FKGP	Q9M2S0	Q9LNJ9	Probable mannose-1-phosphate guanylyltransferase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	Bifunctional fucokinase/fucose pyrophosphorylase; Bifunctional enzyme involved in the salvage pathway which converts free L-fucose to GDP-L-fucose. The sugar-1-kinase activity has a strict substrate specificity for L-fucose and ATP. The pyrophosphorylase activity has a strict substrate specificity for L- fucose 1-phosphate and GTP.	0.698
T22E16.250	VTC2	Q9M2S0	Q8RWE8	Probable mannose-1-phosphate guanylyltransferase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	0.473
T22E16.250	VTC5	Q9M2S0	Q9FLP9	Probable mannose-1-phosphate guanylyltransferase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	GDP-L-galactose phosphorylase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	0.403
VTC2	CYT1	Q8RWE8	O22287	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate.	0.955
VTC2	F17I23.90	Q8RWE8	Q8H1Q7	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	Probable mannose-1-phosphate guanylyltransferase 3; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	0.405
VTC2	T22E16.250	Q8RWE8	Q9M2S0	GDP-L-galactose phosphorylase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L- galactose and GDP-D-glucose as substrates. Lower activity with GDP-L- fucose, very low activity with GDP-D-mannose, and no activity with UDP- D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.	Probable mannose-1-phosphate guanylyltransferase 2; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.	0.473