STRINGSTRING
PTM PTM NF-YB11 NF-YB11 SWI3C SWI3C ATX4 ATX4 REF6 REF6 T21P5.12 T21P5.12 MBD9 MBD9 FHA2 FHA2 F26O13.140 F26O13.140 T16K5.180 T16K5.180 F17I23.30 F17I23.30 F16L2_40 F16L2_40 ARP9 ARP9 LFR LFR F2D10.15 F2D10.15 K3M16.80 K3M16.80 CHC1-2 CHC1-2 RIN1 RIN1 K9I9.20 K9I9.20 SWC6 SWC6 TAF14B TAF14B RLT2 RLT2 UCH1 UCH1 ARP4A ARP4A F13N6.4 F13N6.4 T8E24.3 T8E24.3 ARP5 ARP5 SWI3A SWI3A SWC4 SWC4 K13P22.4 K13P22.4 INO80 INO80 Q8RWS0_ARATH Q8RWS0_ARATH MBB18.24 MBB18.24 ARP6 ARP6 F28J12.60 F28J12.60 ATX5 ATX5 MTI20.17 MTI20.17 ARP4 ARP4 T14C9.120 T14C9.120 SWI3B SWI3B PIE1 PIE1 T6A9.31 T6A9.31 YY1 YY1 F1C9.33 F1C9.33 BSH BSH F15M4.12 F15M4.12 F8A5.22 F8A5.22 F12A21.9 F12A21.9 RLT1 RLT1 F10A5.25 F10A5.25 F7G19.7 F7G19.7 DDR4 DDR4 SWC2 SWC2 T13L16.5 T13L16.5 emb1967 emb1967 F4JPL2_ARATH F4JPL2_ARATH F4K0Y2_ARATH F4K0Y2_ARATH MAC12.8 MAC12.8 MAH20.19 MAH20.19 MDJ22.18 MDJ22.18 UCH2 UCH2 MSI3 MSI3 T8I13.19 T8I13.19
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
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PTMDDT domain-containing protein PTM; Membrane-bound transcription factor required for the plastid- to-nucleus retrograde signaling. Functions in multiple retrograde pathways. The plastid-to-nucleus signal plays an important role in the coordinated expression of both nuclear- and chloroplast-localized genes that encode photosynthesis-related proteins. In the nucleus, activates ABI4 transcription in a PHD-dependent manner associated with histone modifications. Localized primarily in the chloroplast outer membrane as dormant form and, in response to retrograde signals, is released from the [...] (1706 aa)
NF-YB11Putative CCAAT-binding transcription factor subunit. (275 aa)
SWI3CSWI/SNF complex subunit SWI3C; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. (807 aa)
ATX4Histone-lysine N-methyltransferase ATX4; Histone methyltransferase. (1027 aa)
REF6Lysine-specific demethylase REF6; Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me. Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay. Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli. Binds DNA via its four zinc fingers in a sequence- specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation. Involved in the regulation of flowering ti [...] (1360 aa)
T21P5.12Mediator of RNA polymerase II transcription subunit-like protein. (354 aa)
MBD9Methyl-CpG-binding domain-containing protein 9; Probable transcriptional regulator that acts as a histone acetyltransferase. Mediates the acetylation of histone H3 and H4 of target loci (e.g. FLC). Involved in an auxin-independent regulation of shoot branching and flowering time. (2176 aa)
FHA2FHA domain-containing protein FHA2; May play a role in the control of plant organ development and specifically in the regulation of stamen development. Does not show transactivation activity in yeast. (320 aa)
F26O13.140At3g51500. (116 aa)
T16K5.180RuvB-like helicase; Belongs to the RuvB family. (473 aa)
F17I23.30At4g30630. (237 aa)
F16L2_40Nuclear factor kappa-B-binding-like protein. (1298 aa)
ARP9Actin-related protein 9. (596 aa)
LFRArmadillo repeat-containing protein LFR; Involved in leaf and flower development. Required for the formation of anther cell layers and normal expression of genes that regulates anther development. (460 aa)
F2D10.15DNA-binding bromodomain-containing protein. (652 aa)
K3M16.80Mediator of RNA polymerase II transcription subunit-like protein. (369 aa)
CHC1-2SWI/SNF complex component SNF12 homolog; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology); Belongs to the SMARCD family. (534 aa)
RIN1RuvB-like protein 1; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. Has single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). (458 aa)
K9I9.20RuvB-like helicase; Belongs to the RuvB family. (469 aa)
SWC6SWR1 complex subunit 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Coodinates SWR1-C, FRI-C (FLC transcription activator complex), histone methyltransferase and general transcription factors. Represses flowering by positively regulating FLC and MAF4. Binds to the promoter region of FLC chromatin. (171 aa)
TAF14BTranscription initiation factor TFIID subunit 14b; Negative regulator of flowering controlling the H4K5 acetylation levels in the FLC and FT chromatin. Positively regulates FLC expression. Component of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of a NuA4 histone acetyltransferase complex which is involved in [...] (268 aa)
RLT2Homeobox-DDT domain protein RLT2; Transcriptional regulator required for the maintenance of the plant vegetative phase. In association with CHR11 or CHR17 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Involved in the transcriptional regulation of seed-specific gene expression. (1694 aa)
UCH1Ubiquitin carboxyl-terminal hydrolase; Ubiquitin-protein hydrolase involved in the release of ubiquitin attached via both peptide and isopeptide linkages. Able to cleave 'Lys-48'-linked polyubiquitin chains. Involved in the direct or indirect regulation of AUX/IAA proteins stability (Probable). Acts as a linker between the TREX-2 complex and 26S proteasome. (334 aa)
ARP4AActin-related protein 4A. (145 aa)
F13N6.4HIT zinc finger and PAPA-1-like domain-containing protein. (537 aa)
T8E24.3PAPA-1-like family protein / zinc finger (HIT type) family protein. (427 aa)
ARP5Actin-related protein 5; Probable subunit of a chromatin-remodeling complex. Involved in DNA repair. Required for multicellular development of all organs. (724 aa)
SWI3ASWI/SNF complex subunit SWI3A; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. (512 aa)
SWC4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. (441 aa)
K13P22.4DNA-binding bromodomain-containing protein. (916 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (By similarity). Binds DNA (By similarity). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (By similarity). Positive regulator of homologous recombination, but not an essential component of homologous recombination. Not involved in the illegitimate repair pathway. Belongs to the SNF2/RAD54 helicase family. (1507 aa)
Q8RWS0_ARATHChromatin-remodeling complex subunit. (124 aa)
MBB18.24Zinc-finger domain of monoamine-oxidase A repressor R1 protein. (572 aa)
ARP6Actin-related protein 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Binds to the promoter region of FLC chromatin. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. [...] (421 aa)
F28J12.60At4g18400. (107 aa)
ATX5Histone-lysine N-methyltransferase ATX5; Histone methyltransferase. (1043 aa)
MTI20.17Ribosomal RNA small subunit methyltransferase G. (207 aa)
ARP4Actin-related protein 4; Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure. (441 aa)
T14C9.120Uncharacterized protein At5g25580. (405 aa)
SWI3BSWI/SNF complex subunit SWI3B; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. May play an essential role in the transition from the vegetative to the reproductive phase of development. May be a p [...] (469 aa)
PIE1Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Probable DNA-dependent ATPase. Not involved in the repression of FLC in gametophytes, but required for the reactivation of FLC in early embryos and for the maintenance of full activation of FLC in late embryos. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (2055 aa)
T6A9.31At1g02290. (443 aa)
YY1Zinc finger transcription factor YY1; Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3'. Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea). Binds to ABR1 promoter and promotes its expression, thus negatively r [...] (387 aa)
F1C9.33SWIB/MDM2 domain superfamily protein. (458 aa)
BSHChromatin structure-remodeling complex protein BSH; Component of a multiprotein complex equivalent of the yeast SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors; Belongs to the SNF5 family. (240 aa)
F15M4.12DNA-binding bromodomain-containing protein. (580 aa)
F8A5.22SMAD/FHA domain-containing protein. (525 aa)
F12A21.9Zinc-finger domain of monoamine-oxidase A repressor R1 protein. (512 aa)
RLT1Homeobox-DDT domain protein RLT1; Transcriptional regulator required for the maintenance of the plant vegetative phase. In association with CHR11 or CHR17 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. (1705 aa)
F10A5.25Forkhead-associated (FHA) domain-containing protein. (555 aa)
F7G19.7JmjC domain protein JMJ24. (944 aa)
DDR4DDT domain-containing protein DDR4; Probable transcription regulator. (750 aa)
SWC2SWR1 complex subunit 2; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. (365 aa)
T13L16.5Phosphatidylinositol 3-and 4-kinase family protein with FAT domain-containing protein; Belongs to the PI3/PI4-kinase family. (3858 aa)
emb1967Forkhead-associated (FHA) domain-containing protein. (702 aa)
F4JPL2_ARATHPhosphotransferases/inositol or phosphatidylinositol kinase; Belongs to the PI3/PI4-kinase family. (3834 aa)
F4K0Y2_ARATHPHD-finger and DNA binding domain-containing protein. (1602 aa)
MAC12.8Nuclear factor kappa-B-binding protein. (954 aa)
MAH20.19DDT domain-containing protein. (723 aa)
MDJ22.18PHD finger family protein. (1566 aa)
UCH2Ubiquitin carboxyl-terminal hydrolase 2; Ubiquitin-protein hydrolase involved in the release of ubiquitin attached via both peptide and isopeptide linkages. Able to cleave 'Lys-48'-linked polyubiquitin chains. Involved in the direct or indirect regulation of AUX/IAA proteins stability. Acts as a linker between the TREX-2 complex and 26S proteasome ; Belongs to the peptidase C12 family. (330 aa)
MSI3WD-40 repeat-containing protein MSI3; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA; Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. (424 aa)
T8I13.19HIT zinc finger and PAPA-1-like domain-containing protein. (486 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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