(38 nodes) Regulation of pollen tube growth network (Arabidopsis thaliana)

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	CPK34	Calcium-dependent protein kinase 34; May play a role in signal transduction pathways that involve calcium as a second messenger; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (523 aa)
	ROPGEF14	Rop guanine nucleotide exchange factor 14; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. (576 aa)
	CLE45	CLAVATA3/ESR (CLE)-related protein 45; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Prevents, in a dose-dependent manner, auxin response in the root meristem thus leading in the repression of protophloem differentiation and periclinal sieve element precursor cell division. (124 aa)
	RALFL19	Protein RALF-like 19; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity). (110 aa)
	AGL65	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth. (389 aa)
	PRK2	Pollen receptor-like kinase 2; Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. Phosphorylates ROPGEF1 in its C-terminal region, releasing its auto-inhibition, and thereby activating the ROP1 signaling pathway. May act as a scaffolding protein, recruiting ROPGEF12 to the plasma membrane by binding to its C-terminal domain. Phosphorylates ROPGEF12, releasing its auto- inhibition. (647 aa)
	ROPGEF1	Rop guanine nucleotide exchange factor 1; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Acts downstream of PRK2 in the control of polarized pollen tube growth by activating ARAC11/ROP1. In association with ROPGEF4, acts as specific regulator of ARAC10/ROP11 function in ABA-mediated stomatal closure. May play a role in the Rac/Rop-signaling pathway that controls ROS-mediated root hair development. (548 aa)
	MYB120	Transcription factor MYB120; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB97 and MYB101, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression. (523 aa)
	KTI2	Kunitz trypsin inhibitor 2; Water-soluble and chlorophyll-binding protein that probably does not function as a chloroplast chlorophyll carrier and is not involved in photosynthesis. Involved in the control of cell death in the transmitting tract and septum epidermis during flower development. Binds and inhibits the activity of the cysteine protease RD21A as a pro-death protein. May play a role in herbivore resistance activation during seedling greening ; Belongs to the protease inhibitor I3 (leguminous Kunitz- type inhibitor) family. (215 aa)
	ROPGEF12	Rop guanine nucleotide exchange factor 12; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. May be recruited by PRK2 at the plasma membrane to maintain polar Rop activity in the pollen tube and control polarized pollen tube growth. (515 aa)
	EXO70C2	Exocyst subunit Exo70 family protein; Component of the exocyst complex. (695 aa)
	CPK17	Calcium-dependent protein kinase 17; May play a role in signal transduction pathways that involve calcium as a second messenger; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (528 aa)
	ATEXO70C1	Exocyst subunit Exo70 family protein; Component of the exocyst complex. (653 aa)
	RALFL4	Protein RALF-like 4; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity). (110 aa)
	RABA4D	Ras-related protein RABA4d; Intracellular vesicle trafficking and protein transport. Plays an important role in the regulation of pollen tube tip growth. (222 aa)
	sks13	BNH protein pectinesterase-like protein pollen-secific protein-like. (551 aa)
	PRK4	Pollen receptor-like kinase 4; Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. Can phosphorylate ROPGEF1 in vitro. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (679 aa)
	AGL104	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth. (335 aa)
	PRK5	Pollen receptor-like kinase 5; Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. The extracellular domain serves as a sensor for peptides derived from GRI. May act as a downstream element for ROS-dependent cell death induced by GRI. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (686 aa)
	VQ20	VQ motif-containing protein 20; May function as negative regulator of plant defense. (285 aa)
	F4IIS6_ARATH	Uncharacterized protein. (98 aa)
	MDA7.8	Leucine-rich receptor-like protein kinase family protein; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1090 aa)
	T13D8.29	Probable nucleoredoxin 1; Probable thiol-disulfide oxidoreductase required for pollen tube growth and pollen function in the pistil. Seems not to be required for in vitro pollen tube growth. May be involved in the generation of lipid signaling molecules in pistil; Belongs to the nucleoredoxin family. (578 aa)
	MYB101	Transcription factor MYB101; Transcription activator. Binds to 5'-CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter (e.g. alpha-amylase) to promote their expression. Positive regulator of abscisic acid (ABA) responses leading to growth arrest during seed germination. Promotes the expression of aleurone-related genes (e.g. CP1, CP, GASA1, BXL1 and BXL2) in seeds. Together with MYB33 and MYB65, promotes the programmed cell death (PCD) leading to vacuolation of protein storage vacuoles (PSVs) in the aleurone layers during seed germination. Maybe involved in the regulation of [...] (490 aa)
	F17H15.18	Probably inactive leucine-rich repeat receptor-like protein kinase At2g25790. (960 aa)
	TFIIB1	Transcription initiation factor IIB-1; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II (By similarity). Interacts with TBP2 and is required for activated transcription and possibly basal transcription. Plays important roles in pollen tube growth, guidance, and reception as well as endosperm development. Is partially functionally different from TFIIB2 and PBRP2. (312 aa)
	AGL30	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth. (386 aa)
	AGL66	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth. (332 aa)
	CPK11	Calcium-dependent protein kinase 11; May play a role in signal transduction pathways that involve calcium as a second messenger. Functions as regulator of the calcium- mediated abscisic acid (ABA) signaling pathway. Phosphorylates ABA- responsive transcription factors ABF1 and ABF4 in vitro. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (495 aa)
	CALS5	Callose synthase 5; Required for the formation of the callose wall separating the tetraspores (interstitial wall) and surrounding the pollen mother cells (pheripheral wall). Required for exine formation on pollen wall. May be involved in callose synthesis during pollen tube growth. During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals. (1923 aa)
	PRK3	Pollen receptor-like kinase 3; Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. Can phosphorylate ROPGEF1 in vitro. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (633 aa)
	MYB97	Transcription factor MYB97; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB101 and MYB120, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression. (389 aa)
	CALS9	Callose synthase 9; Involved in sporophytic and gametophytic development. Required for normal plant development. During pollen formation, required for the entry of microspores into mitosis and microspore symmetric division. May be required for correct temporal and spatial control of callose deposition during pollen mitosis. During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals. (1890 aa)
	CPK24	Calcium-dependent protein kinase 24; May play a role in signal transduction pathways that involve calcium as a second messenger; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (582 aa)
	F3K23.24	Probable receptor-like protein kinase At2g21480. (871 aa)
	ROPGEF9	Rop guanine nucleotide exchange factor 9; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. (517 aa)
	F19H22.210	Probable receptor-like protein kinase At4g39110. (878 aa)
	LLG3	GPI-anchored protein LLG3. (160 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGL104	AGL30	Q9LM46	Q1PFA4	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.500
AGL104	AGL65	Q9LM46	Q7X9I0	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.854
AGL104	AGL66	Q9LM46	Q1PFC2	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.535
AGL104	MYB120	Q9LM46	Q94FL7	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB120; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB97 and MYB101, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.541
AGL104	MYB97	Q9LM46	Q9S773	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB97; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB101 and MYB120, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.439
AGL104	RALFL4	Q9LM46	Q9FZA0	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Protein RALF-like 4; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).	0.588
AGL30	AGL104	Q1PFA4	Q9LM46	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.500
AGL30	AGL66	Q1PFA4	Q1PFC2	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.646
AGL30	MYB120	Q1PFA4	Q94FL7	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB120; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB97 and MYB101, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.719
AGL30	MYB97	Q1PFA4	Q9S773	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB97; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB101 and MYB120, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.739
AGL30	VQ20	Q1PFA4	Q9LS54	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	VQ motif-containing protein 20; May function as negative regulator of plant defense.	0.540
AGL65	AGL104	Q7X9I0	Q9LM46	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.854
AGL65	AGL66	Q7X9I0	Q1PFC2	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.706
AGL65	MYB120	Q7X9I0	Q94FL7	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB120; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB97 and MYB101, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.570
AGL65	MYB97	Q7X9I0	Q9S773	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB97; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB101 and MYB120, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.599
AGL66	AGL104	Q1PFC2	Q9LM46	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL104; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL30 and AGL65 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.535
AGL66	AGL30	Q1PFC2	Q1PFA4	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL30; Probable transcription factor that forms heterodimers with the MADS-box proteins AGL66 and AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.646
AGL66	AGL65	Q1PFC2	Q7X9I0	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Agamous-like MADS-box protein AGL65; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL104 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	0.706
AGL66	MYB120	Q1PFC2	Q94FL7	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB120; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB97 and MYB101, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.574
AGL66	MYB97	Q1PFC2	Q9S773	Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth.	Transcription factor MYB97; Transcription activator. Binds to 5'- CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter to promote their expression (By similarity). Together with MYB101 and MYB120, functions as a male factor that controls pollen tube-synergid interaction in fertilization. Required for pollen tube growth arrest and sperm cell release in the female gametophyte, probably via the regulation of pollen tube-specific gene expression.	0.515