STRINGSTRING
CBP60C CBP60C CBP60A CBP60A CBP60E CBP60E CBP60F CBP60F CBP60G CBP60G BIK1 BIK1 CBP60D CBP60D AT5G22070 AT5G22070 SARD1 SARD1 CBP60B CBP60B GRI GRI PCRK2 PCRK2 PAD4 PAD4 PCRK1 PCRK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBP60CCalmodulin-binding protein 60 C; Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes. (622 aa)
CBP60ACalmodulin-binding protein 60 A; Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes. (494 aa)
CBP60ECalmodulin-binding protein 60 E; Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes; Belongs to the plant ACBP60 protein family. (599 aa)
CBP60FCalmodulin-binding protein 60 F; Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes; Belongs to the plant ACBP60 protein family. (562 aa)
CBP60GCalmodulin-binding protein 60 G; Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes. Recruited to the promoter of ICS1 and other defense-related genes (e.g. PR1, PR2 and EDS5) in response to both biotic (e.g. Pseudomonas syringae pv. maculicola ES4326, P. syringae pv. tomato DC3000, and microbe- associated molecular patterns (MAMPs) such as flg22) and abiotic stresses (e.g. UV-B, drought and abscisic acid), thus triggering rapid defense responses by stimulating salicylic acid (SA) biosynthesis. Involved in b [...] (563 aa)
BIK1Serine/threonine-protein kinase BIK1; Plays a central role in immune responses. Required to activate the resistance responses to necrotrophic pathogens. Phosphorylates FLS2 and BAK1. Involved in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling and defense responses downstream of FLS2. Acts additively with PBL1 in PTI defenses. Acts as positive regulator of the PAMP flg22-induced increase of cytosolic calcium. Binds directly and phosphorylates the NADPH oxidase RBOHD at specific sites in a calcium-independent manner to enhance reactive oxygen species (ROS) [...] (395 aa)
CBP60DCalmodulin-binding protein 60 D; Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes; Belongs to the plant ACBP60 protein family. (601 aa)
AT5G22070Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein. (362 aa)
SARD1Protein SAR DEFICIENT 1; Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes. Recruited to the promoter of ICS1 and other defense-related genes (e.g. PR1 and SID2) in response to both biotic (e.g. Pseudomonas syringae pv. maculicola ES4326) and abiotic stresses (e.g. UV-B), thus triggering slow defense responses by stimulating salicylic acid (SA) biosynthesis. Required for basal and systemic acquired resistance to P. syringae pv. maculicola and Hyaloperonospora arabidopsidis. Belongs to the plant ACBP60 prote [...] (451 aa)
CBP60BCalmodulin-binding protein 60 B; Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes; Belongs to the plant ACBP60 protein family. (647 aa)
GRIProtein GRIM REAPER; Involved in the regulation of cell death induced by extracellular reactive oxygen species. Only the processed peptide, and not the full length GRI can bind in vivo to the extracellular domain of the receptor PRK5. The GRIp-induced cell death is superoxide and salicylic acid dependent. Belongs to the STIG1 family. (168 aa)
PCRK2Serine/threonine-protein kinase PCRK2; Functions redundantly with PCRK1 in basal resistance against bacterial pathogens and in regulation of plant immunity. Functions together with PCRK1 downstream of the pathogen-associated molecular pattern (PAMP) receptor FLS2. Contributes to the induction of SARD1 and CBP60G, which are transcriptional activator of ICS1, an enzyme involved in salicylate (SA) biosynthesis upon pathogen attack. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (420 aa)
PAD4Lipase-like PAD4; Probable lipase required downstream of MPK4 for accumulation of the plant defense-potentiating molecule, salicylic acid, thus contributing to the plant innate immunity against invasive biotrophic pathogens and to defense mechanisms upon recognition of microbe- associated molecular patterns (MAMPs). Participates in the regulation of various molecular and physiological processes that influence fitness. Together with SG101, required for programmed cell death (PCD) triggered by NBS-LRR resistance proteins (e.g. RPS4, RPW8.1 and RPW8.2) in response to the fungal toxin fumo [...] (541 aa)
PCRK1Serine/threonine-protein kinase PCRK1; Involved in the activation of early immune responses. Plays a role in pattern-triggered immunity (PTI) induced by pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Contributes to PTI in response to the bacterial pathogen Pseudomonas syringae pv maculicola strain ES4326. Contributes to PTI in response to the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000. Functions redundantly with PCRK2 in basal resistance against bacterial pathogens and in regulation of plant immunity. Functions toge [...] (418 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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