STRINGSTRING
FRG3 FRG3 CHR12 CHR12 CHR7 CHR7 CHR17 CHR17 CHR23 CHR23 CLSY2 CLSY2 MXM12.5 MXM12.5 CHR4 CHR4 CHR25 CHR25 BRM BRM PIE1 PIE1 CHR11 CHR11 INO80 INO80 CHR24 CHR24 CHR28 CHR28 MUG13.1 MUG13.1 RAD5B RAD5B RAD5A RAD5A CHR27 CHR27 CLSY4 CLSY4 T14E10.30 T14E10.30 CLSY1 CLSY1 PKL PKL DRD1 DRD1 DDM1 DDM1 ETL1 ETL1 CHR8 CHR8 CHR18 CHR18 A0A1P8AWF9 A0A1P8AWF9 CHR34 CHR34 BTAF1 BTAF1 FRG5 FRG5 EDA16 EDA16 ATRX ATRX SWI2 SWI2 CLSY3 CLSY3 SYD SYD T7D17.5 T7D17.5 CHR10 CHR10 CHR5 CHR5
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FRG3annotation not available (638 aa)
CHR12Probable ATP-dependent DNA helicase CHR12; Probable chromatin-remodeling factor that is functionally redundant with CHR23 in root and shoot stem cell initiation, and root apical meristem (RAM) and shoot apical meristem (SAM) maintenance. Plays an important role in mediating the temporary plant growth arrest induced upon perception of stress. May promote seed maturation and repress initiation of germination. (1102 aa)
CHR7CHD3-type chromatin-remodeling factor CHR7; Chromatin remodeling factor that represses the expression of embryonic trait genes upon and after seed germination and thus enables the developmental switch to post-germinative growth. (1202 aa)
CHR17ISWI chromatin-remodeling complex ATPase CHR17; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Necessar [...] (1069 aa)
CHR23Probable ATP-dependent DNA helicase CHR23; Probable chromatin-remodeling factor that is functionally redundant with CHR12 in root and shoot stem cell initiation and root apical meristem (RAM) and shoot apical meristem (SAM) maintenance. Can associate with the promoter region of WOX5. May promote seed maturation and repress initiation of germination. May repress plant growth. (1064 aa)
CLSY2SNF2 domain-containing protein CLASSY 2; Probable chromatin remodeling factor. (1261 aa)
MXM12.5annotation not available (1194 aa)
CHR4Protein CHROMATIN REMODELING 4; Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3 (By similarity). Probable chromatin remodeling factor. Belongs to the SNF2/RAD54 helicase family. (2223 aa)
CHR25Protein CHROMATIN REMODELING 25; Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments. Addition of RAD54 overcomes inhibition of DNA strand exchange by RAD51 bound to substrate dsDNA. Species preference in the RAD51 dissociation and DNA strand exchange assays underlines the importance of specific RAD54-RAD51 interactions. RAD51 is unable to release dsDNA upon ATP hydrolysis, leaving it stuck on the heteroduplex DNA product after DNA strand exchange (By similarity). Involved in DNA repair and mitotic recombina [...] (910 aa)
BRMATP-dependent helicase BRM; ATPase subunit of a multiprotein complex equivalent of the SWI/SNF complex that acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. Represses embryonic genes in leaves and controls shoot development and flowering. Activates flower homeotic genes. The association of BRM with its target genes requires REF6. Necessary to acquire heat stress (HS) memory, by globally binding to HS memory genes. (2193 aa)
PIE1Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Probable DNA-dependent ATPase. Not involved in the repression of FLC in gametophytes, but required for the reactivation of FLC in early embryos and for the maintenance of full activation of FLC in late embryos. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (2055 aa)
CHR11ISWI chromatin-remodeling complex ATPase CHR11; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Involved in nuclear proliferation during megagametogenesis and cell expansion in the sporophyte. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key [...] (1056 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (By similarity). Binds DNA (By similarity). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (By similarity). Positive regulator of homologous recombination, but not an essential component of homologous recombination. Not involved in the illegitimate repair pathway. Belongs to the SNF2/RAD54 helicase family. (1507 aa)
CHR24Protein CHROMATIN REMODELING 24; DNA helicase that acts as an essential component of the spindle assembly checkpoint (By similarity). Probable chromatin remodeling factor that regulate homologous recombination (HR) and non- homologous recombination (NHR). (1090 aa)
CHR28Helicase-like transcription factor CHR28; Probable helicase-like transcription factor involved in transcriptional gene silencing. Associates with SUVR2 and contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. May be involved in nucleosome positioning to form ordered nucleosome arrays on chromatin. Associates with SUVR2 and functions redundantly with FRG1. Required for the efficient methylation of a broad range of RdDM target loci. (981 aa)
MUG13.1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily. (881 aa)
RAD5BDNA repair protein RAD5B; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for DNA repair. Does not seem to be required for DNA repair and regulation of homologous recombination (HR) ; Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily. (1277 aa)
RAD5ADNA repair protein RAD5A; Functions in error-free postreplication DNA repair or DNA- damage tolerance (DTT) pathway. Required for homologous recombination (HR) induced by DNA double-strand break (DSB) in somatic cells. Required for damage- induced DNA repair, independently of MUS81 and RECQL4A. Plays a role in synthesis-dependent strand annealing (SDSA) but not in single-strand annealing (SSA). Possesses double-stranded DNA- dependent ATPase activity. Is able to regress replication forks with preference for forks with a leading strand gap. Is able to catalyze branch migration of Hollid [...] (1029 aa)
CHR27Helicase-like transcription factor CHR27; Probable helicase-like transcription factor involved in transcriptional gene silencing. Associates with SUVR2 and contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. May be involved in nucleosome positioning to form ordered nucleosome arrays on chromatin. Associates with SUVR2 and functions redundantly with FRG2. Required for the efficient methylation of a broad range of RdDM target loci. (1047 aa)
CLSY4SNF2 domain-containing protein CLASSY 4; Probable chromatin remodeling factor. (1132 aa)
T14E10.30F-box protein At3g54460; Belongs to the helicase family. (1378 aa)
CLSY1SNF2 domain-containing protein CLASSY 1; Probable chromatin remodeling factor. Required for the initial establishment of DNA methylation and for accumulation of 24-nt siRNAs. May act on RNA templates by remodeling ribonucleoprotein structures and thereby influencing the availability of the RNA to polymerases. (1256 aa)
PKLCHD3-type chromatin-remodeling factor PICKLE; Chromatin remodeling factor that represses the expression of embryonic trait genes (such as NFYB9/LEC1) upon and after seed germination and thus enables the developmental switch to post- germinative growth. Silences some MADS-box proteins such as PHE1 and PHE2. Plays a role during carpel differentiation. Regulates late processes in cytokinin signaling. (1384 aa)
DRD1Protein CHROMATIN REMODELING 35; Subunit of the chromatin-remodeling complex (DDR complex) that mediates RNA polymerases IV and V (Pol IV and Pol V) recruitment to chromatin. Cooperates with Pol IV and Pol V to regulates RNA- and RNAi- (RNA interference) directed non- CpG de novo DNA methylation on cytosine of genes targeted for silencing and enhancers, also known as siRNA-directed DNA methylation (RdDM), thus leading to epigenetic modification of the genome and promoting/maintaining heterochromatin. In collaboration with Pol V, mediates/maintains, in cis, methylation- associated self- [...] (888 aa)
DDM1ATP-dependent DNA helicase DDM1; ATP-dependent DNA helicase that plays a role in formation, organization, stability and heritability of heterochromatin and thus regulates several physiological traits. Binds to the nucleosome and promotes chromatin remodeling in an ATP-dependent manner; induces nucleosome repositioning on a short DNA fragment, and, possibly, could be guided to target sites (including silent transposable elements) by small interfering RNAs (siRNAs). Can bind both free and nucleosomal DNA. Required for the heritable maintenance of genome integrity and transcriptional gene [...] (764 aa)
ETL1Protein CHROMATIN REMODELING 19; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double- strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs (By similarity). Probable chromatin remodeling factor. Probable helicase-like transcription factor involved in transcriptional gene silencing. Associates with SUVR2 and contributes to transcriptional gene silencing at RNA-directed DNA methylati [...] (763 aa)
CHR8Protein CHROMATIN REMODELING 8; Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation; Belongs to the SNF2/RAD54 helicase family. (1187 aa)
CHR18Chromatin remodeling factor18. (678 aa)
A0A1P8AWF9Helicase protein with RING/U-box domain-containing protein. (876 aa)
CHR34Chromatin remodeling 34. (823 aa)
BTAF1TATA-binding protein-associated factor BTAF1; Involved in meristem development. Acts as positive regulator of the CUC-STM pathway in shoot apical meristem (SAM) neo-formation. Belongs to the helicase family. (2045 aa)
FRG5annotation not available (1270 aa)
EDA16annotation not available (1280 aa)
ATRXProtein CHROMATIN REMODELING 20; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes (By similarity). Involved in DNA repair of gamma-irradiation-mediated damages. (1479 aa)
SWI2Switch 2; May be involved in early DNA damage response (By similarity). Probable chromatin remodeling factor. (862 aa)
CLSY3SNF2 domain-containing protein CLASSY 3; Probable chromatin remodeling factor. (1410 aa)
SYDChromatin structure-remodeling complex protein SYD; Catalytic component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls stem cell fate via the transcription regulation of WUS in the shoot apical meristem, by modulating its promoter. LFY-dependent repressor of the meristem identity switch from vegetative to reproductive development probably by modulating chromatin state. Involved in the regulation of floral homeotic gene expression in response to environmental stimuli. Required for carpel and ovule d [...] (3574 aa)
T7D17.5RING-finger, DEAD-like helicase, PHD and SNF2 domain-containing protein. (1664 aa)
CHR10Probable helicase CHR10; Probable helicase-like transcription factor. (877 aa)
CHR5Protein CHROMATIN REMODELING 5; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3 (By similarity). Probable chromatin remodeling factor. (1724 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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