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WIT2 | WPP domain-interacting tail-anchored protein 2; Together with WIT1, required for the nuclear envelope docking of RANGAP proteins in root tips. Plays a role in nuclear shape determination. As component of the SUN- WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes. (627 aa) | ||||
XI-I | Myosin-15; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria. Plays a role in nuclear shape determination. Drives nuclear movement along actin filaments. As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasm [...] (1522 aa) | ||||
SUN1 | SUN domain-containing protein 1; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for the maintenance and/or formation of polarized nuclear shape in root hairs. Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis. As component of the SUN-WIP-WIT2-KAKU1 [...] (471 aa) |