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| | A0A1P8B2G7 | SNF2 domain CLASSY-like protein. (211 aa) |
| | CHR34 | Chromatin remodeling 34. (823 aa) |
| | A0A1P8BFD5 | Paired amphipathic helix Sin3-like protein. (122 aa) |
| | F15M4.12 | DNA-binding bromodomain-containing protein. (580 aa) |
| | F3I6.16 | Paired amphipathic helix (PAH2) superfamily protein. (245 aa) |
| | B3H691_ARATH | PHD finger protein. (73 aa) |
| | F17L21.2 | Paired amphipathic helix repeat-containing protein. (184 aa) |
| | F17L21.32 | Paired amphipathic helix (PAH2) superfamily protein. (222 aa) |
| | F17L21.6 | Paired amphipathic helix (PAH2) superfamily protein. (225 aa) |
| | CRWN1 | Protein CROWDED NUCLEI 1; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (By similarity). Required for nucleus structure organization (e.g. size and shape). (1132 aa) |
| | F1N21.9 | Zinc-finger domain of monoamine-oxidase A repressor R1 protein. (493 aa) |
| | ASY1 | Meiosis-specific protein ASY1; Required for normal meiosis in male and female gametophytes. Plays a crucial role in coordinating the activity of DMC1, a key member of the homologous recombination machinery. Acts at the interface between the developing chromosome axes and the recombination machinery to ensure DMC1-mediated interhomolog recombination. (596 aa) |
| | F12A21.9 | Zinc-finger domain of monoamine-oxidase A repressor R1 protein. (512 aa) |
| | RLT1 | Homeobox-DDT domain protein RLT1; Transcriptional regulator required for the maintenance of the plant vegetative phase. In association with CHR11 or CHR17 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. (1705 aa) |
| | F7G19.7 | JmjC domain protein JMJ24. (944 aa) |
| | UBN2 | Ubinuclein-2; May be required for replication-independent chromatin assembly; Belongs to the ubinuclein family. (717 aa) |
| | F3I6.13 | Paired amphipathic helix (PAH2) superfamily protein. (196 aa) |
| | DDR4 | DDT domain-containing protein DDR4; Probable transcription regulator. (750 aa) |
| | SYD | Chromatin structure-remodeling complex protein SYD; Catalytic component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls stem cell fate via the transcription regulation of WUS in the shoot apical meristem, by modulating its promoter. LFY-dependent repressor of the meristem identity switch from vegetative to reproductive development probably by modulating chromatin state. Involved in the regulation of floral homeotic gene expression in response to environmental stimuli. Required for carpel and ovule d [...] (3574 aa) |
| | T18C6.25 | Transcription factor-like protein. (196 aa) |
| | SWC2 | SWR1 complex subunit 2; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. (365 aa) |
| | T13L16.5 | Phosphatidylinositol 3-and 4-kinase family protein with FAT domain-containing protein; Belongs to the PI3/PI4-kinase family. (3858 aa) |
| | F4J364_ARATH | Uncharacterized protein. (1176 aa) |
| | F4J5A7_ARATH | RNA recognition motif (RRM)-containing protein. (987 aa) |
| | F4J923_ARATH | ATP-dependent helicase family protein. (393 aa) |
| | F4JA84_ARATH | ATP-dependent helicase family protein. (474 aa) |
| | F4JA85_ARATH | DNA repair protein-like protein. (327 aa) |
| | EMB2423 | Embryo defective 2423. (1027 aa) |
| | GTC2 | GTC2. (343 aa) |
| | F4JPL2_ARATH | Phosphotransferases/inositol or phosphatidylinositol kinase; Belongs to the PI3/PI4-kinase family. (3834 aa) |
| | CHR7 | CHD3-type chromatin-remodeling factor CHR7; Chromatin remodeling factor that represses the expression of embryonic trait genes upon and after seed germination and thus enables the developmental switch to post-germinative growth. (1202 aa) |
| | PTM | DDT domain-containing protein PTM; Membrane-bound transcription factor required for the plastid- to-nucleus retrograde signaling. Functions in multiple retrograde pathways. The plastid-to-nucleus signal plays an important role in the coordinated expression of both nuclear- and chloroplast-localized genes that encode photosynthesis-related proteins. In the nucleus, activates ABI4 transcription in a PHD-dependent manner associated with histone modifications. Localized primarily in the chloroplast outer membrane as dormant form and, in response to retrograde signals, is released from the [...] (1706 aa) |
| | ELP1 | EDM2-like protein1. (677 aa) |
| | F4K0Y2_ARATH | PHD-finger and DNA binding domain-containing protein. (1602 aa) |
| | EDM2 | Protein ENHANCED DOWNY MILDEW 2; Cellular antisilencing factor and regulator of genome DNA methylation patterns involved in the regulation of chromatin states. Together with SUVH4, monitors repressive epigenetic marks H3K27me1, H3K9me2, and prevents DNA-methylation at CHG sites, affecting especially the expression of transposons and developmentally important genes. Regulates alternative RNA processing such as distal 3' polyadenylation by intronic heterochromatin. Transcription factor that binds DNA and contributes to transcriptional transposable element (TE) silencing by modulating lev [...] (1297 aa) |
| | F2G14.150 | Paired amphipathic helix Sin3-like protein. (139 aa) |
| | MAH20.19 | DDT domain-containing protein. (723 aa) |
| | MDJ22.18 | PHD finger family protein. (1566 aa) |
| | MQD22.4 | Transcription factor jumonji (Jmj) family protein / zinc finger (C5HC2 type) family protein. (787 aa) |
| | UCH2 | Ubiquitin carboxyl-terminal hydrolase 2; Ubiquitin-protein hydrolase involved in the release of ubiquitin attached via both peptide and isopeptide linkages. Able to cleave 'Lys-48'-linked polyubiquitin chains. Involved in the direct or indirect regulation of AUX/IAA proteins stability. Acts as a linker between the TREX-2 complex and 26S proteasome ; Belongs to the peptidase C12 family. (330 aa) |
| | SNL4 | Paired amphipathic helix protein Sin3-like 4; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1326 aa) |
| | F17L21.3 | Paired amphipathic helix (PAH2) superfamily protein. (186 aa) |
| | F17L21.4 | Paired amphipathic helix (PAH2) superfamily protein. (137 aa) |
| | HDA19 | Histone deacetylase 19; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDA19 is involved in jasmonic acid and ethylene signaling of pathogen response. Part of a repressor complex including APETALA2 (AP2) and TOPLESS (TPL) that control the expression domains of numerous flora [...] (501 aa) |
| | MSI3 | WD-40 repeat-containing protein MSI3; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA; Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. (424 aa) |
| | SUVH2 | Histone-lysine N-methyltransferase family member SUVH2; Histone methyltransferase family member that plays a central role in gene silencing. Together with MORC6 and SUVH9, regulates the silencing of some transposable elements (TEs). According to it is required for normal methylation of 'Lys-9' and 'Lys-27' of histone H3, 'Lys-20' of H4, and cytosine, but see no significant effect on histone methylation when the gene is mutated. According to the protein does not bind S-adenosyl-L-methionine and lacks methyltransferase activity. Instead, it may function downstream of DRM2 in RNA-directed [...] (651 aa) |
| | T8I13.19 | HIT zinc finger and PAPA-1-like domain-containing protein. (486 aa) |
| | ATXR3 | Histone-lysine N-methyltransferase ATXR3; Histone methyltransferase specifically required for trimethylation of 'Lys-4' of histone H3 (H3K4me3) and is crucial for both sporophyte and gametophyte development. (2335 aa) |
| | H2AV | Histone H2A variant 1; Variant histone H2A which may replace conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa) |
| | H2B | Histone H2B.6; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (150 aa) |
| | dl3985w | Condensin-2 complex subunit. (1314 aa) |
| | SNL3 | Paired amphipathic helix protein Sin3-like 3; Acts as a transcriptional repressor. Interacts with ERF7 to repress genes in abscisic acid and drought stress responses. The heterodimer represses transcription by tethering SNL3 to DNA. (1330 aa) |
| | F3I6.15 | Paired amphipathic helix repeat-containing protein. (744 aa) |
| | F3I6.18 | Paired amphipathic helix (PAH2) superfamily protein. (252 aa) |
| | HMGB1 | High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family. (178 aa) |
| | HMGB2 | High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses. (144 aa) |
| | HMGB5 | High mobility group B protein 5; Binds preferentially double-stranded DNA. Confers resistance to salt and drought stresses. (125 aa) |
| | SAP18 | Histone deacetylase complex subunit SAP18; Links the histone deacetylase complex to transcriptional repressors bound to chromatin. Involved in the tethering of the SIN3 complex to core histone proteins. (152 aa) |
| | SUVR5 | Histone-lysine N-methyltransferase SUVR5; Histone methyltransferase that functions together with its binding partner LDL1/SWP1 as one of the regulators of flower timing in Arabidopsis. Mediates H3K9me2 deposition and regulates gene expression in a DNA methylation-independent manner. Binds DNA through its zinc fingers and represses the expression of a subset of stimulus response genes. May represent a novel mechanism for plants to regulate their chromatin and transcriptional state, which may allow for the adaptability and modulation necessary to rapidly respond to environment or develop [...] (1382 aa) |
| | F1N20.160 | Probable F-box protein At4g22060. (399 aa) |
| | ACR9 | ACT domain-containing protein ACR9; May bind amino acids. (411 aa) |
| | SPT16 | FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1074 aa) |
| | RDR2 | RNA-dependent RNA polymerase 2; RNA-dependent direct polymerase involved in the production of small interfering RNAs (siRNAs). Required for the biogenesis of endogenous siRNAs of 24 nucleotide which derive from heterochromatin and DNA repeats such as transposons or endogenous gene tandem repeats, such as repeats present in FWA gene. Involved in transcriptional gene silencing (TGS). Component of the RNA-directed DNA methylation (RdDM) silencing pathway that utilizes siRNAs to guide DNA methyltransferases to asymmetric cytosines. Involved in control of flowering time through RdDM of FWA [...] (1133 aa) |
| | UBC1 | Ubiquitin-conjugating enzyme E2 1; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. (152 aa) |
| | HTB4 | Histone H2B.11; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (150 aa) |
| | UBC2 | Ubiquitin-conjugating enzyme E2 2; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. (152 aa) |
| | UBC3 | Ubiquitin-conjugating enzyme E2 3; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. (150 aa) |
| | HTR4 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa) |
| | HTR2 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa) |
| | F24B9.25 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | BSH | Chromatin structure-remodeling complex protein BSH; Component of a multiprotein complex equivalent of the yeast SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors; Belongs to the SNF5 family. (240 aa) |
| | HMGB3 | High mobility group B protein 3; Binds preferentially double-stranded DNA. (141 aa) |
| | M550_ARATH | Uncharacterized mitochondrial protein AtMg00550. (160 aa) |
| | CLF | Histone-lysine N-methyltransferase CLF; Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. Required to regulate floral development by repressing the AGAMOUS homeotic gene in leaves, inflorescence stems and flowers. Together with ATX1, modulates AG nucleosome methylation statement. Regulates the antero-posterior organization of the endosperm, as well as the division and elongation rates of leaf cells. PcG proteins act by forming multiprotein complex [...] (902 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (646 aa) |
| | MBD4L | Methyl-CpG-binding domain protein 4-like protein; Monofunctional DNA glycosylase targeting U:G and T:G mispairs. Excises uracil derivatives and exhibits a preference for a CpG sequence context, irrespective of the methylation status of the complementary strand. The activity follows a biphasic kinetics, with an initial burst of product accumulation followed by a slower phase. Specifically binds its reaction product. Triggers the base excision repair (BER) pathway. (445 aa) |
| | CHR25 | Protein CHROMATIN REMODELING 25; Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments. Addition of RAD54 overcomes inhibition of DNA strand exchange by RAD51 bound to substrate dsDNA. Species preference in the RAD51 dissociation and DNA strand exchange assays underlines the importance of specific RAD54-RAD51 interactions. RAD51 is unable to release dsDNA upon ATP hydrolysis, leaving it stuck on the heteroduplex DNA product after DNA strand exchange (By similarity). Involved in DNA repair and mitotic recombina [...] (910 aa) |
| | F1C9.33 | SWIB/MDM2 domain superfamily protein. (458 aa) |
| | F13J11.12 | Nuclease. (343 aa) |
| | ASHH2 | Histone-lysine N-methyltransferase ASHH2; Histone methyltransferase involved in di and tri-methylation of 'Lys-36' of histone H3 (H3K36me2 and H3K36me3). Binds to H3 already mono- or di-methylated on 'Lys-4'(H3K4me1 or H3K4me2), but not to H3K4me3. H3K4me and H3K36me represent specific tags for epigenetic transcriptional activation. Regulates positively FLC transcription to prevent early flowering transition. Required for flowering transition in response to vernalization and for the maintenance of FLC expression in late embryos, but dispensable for the initial reactivation in early emb [...] (1759 aa) |
| | YY1 | Zinc finger transcription factor YY1; Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3'. Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea). Binds to ABR1 promoter and promotes its expression, thus negatively r [...] (387 aa) |
| | HMGB4 | High mobility group B protein 4; Binds preferentially double-stranded DNA. (138 aa) |
| | AGDP1 | Protein AGENET DOMAIN (AGD)-CONTAINING P1; Heterochromatin-binding protein that preferentially occupies long transposons and specifically recognizes the histone H3 'Lys-9' methylation (H3K9me) marks, whith a stronger affinity for dimethylated H3K9 (H3K9me2). Required for transcriptional silencing, non-CG DNA methylation (e.g. CHG and CHH regions), and H3K9 dimethylation (H3K9me2) at some loci. Mediates heterochromatin phase separation and chromocenter formation. (517 aa) |
| | SMC3 | Structural maintenance of chromosomes protein 3; Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity). Essential protein plant viabili [...] (1204 aa) |
| | MMD1 | PHD finger protein MALE MEIOCYTE DEATH 1; Probable transcription factor required for chromosome organization and progression during male meiosis (e.g. microsporogenesis). (704 aa) |
| | PIE1 | Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Probable DNA-dependent ATPase. Not involved in the repression of FLC in gametophytes, but required for the reactivation of FLC in early embryos and for the maintenance of full activation of FLC in late embryos. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (2055 aa) |
| | MNF13.4 | Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. (287 aa) |
| | SWI3B | SWI/SNF complex subunit SWI3B; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. May play an essential role in the transition from the vegetative to the reproductive phase of development. May be a p [...] (469 aa) |
| | T14C9.120 | Uncharacterized protein At5g25580. (405 aa) |
| | ARID1 | AT-rich interactive domain-containing protein 1. (562 aa) |
| | ARP4 | Actin-related protein 4; Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure. (441 aa) |
| | F20P5.23 | Paired amphipathic helix (PAH2) superfamily protein. (160 aa) |
| | MTI20.17 | Ribosomal RNA small subunit methyltransferase G. (207 aa) |
| | F6F3.14 | Zinc finger CCCH domain-containing protein 1. (343 aa) |
| | K21L13.5 | Transcription initiation factor TFIID subunit. (605 aa) |
| | MND1 | Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1/LIM15- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double- strand breaks. (230 aa) |
| | ATX5 | Histone-lysine N-methyltransferase ATX5; Histone methyltransferase. (1043 aa) |
| | ZFN3 | Zinc finger CCCH domain-containing protein 57. (375 aa) |
| | APC13 | Anaphase-promoting complex subunit 13; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Regulates global growth and development, including phyllotaxis and apical dominance. Required for pollen maturation. Promotes (pri) miRNA transcription of each MIR159 genes. (63 aa) |
| | F3I6.14 | Paired amphipathic helix (PAH2) superfamily protein. (155 aa) |
| | F28J12.60 | At4g18400. (107 aa) |
| | ARP6 | Actin-related protein 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Binds to the promoter region of FLC chromatin. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. [...] (421 aa) |
| | FPA | Flowering time control protein FPA; Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels. Required for RNA-mediated chromatin silencing of a range of loci in the genome. Cotranscriptionally recognizes aberrant RNA and marks it for silencing. Controls alternative cleavage and polyadenylation on pre-mRNAs and antisense RNAs. Acts redundantly with FCA to prevent the expression of distally polyadenylated antisense RNAs at the FLC locus; Belongs to the RRM Spen family. (901 aa) |
| | HTR12 | Histone H3-like centromeric protein HTR12; Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity). (178 aa) |
| | MBB18.24 | Zinc-finger domain of monoamine-oxidase A repressor R1 protein. (572 aa) |
| | YAK1 | Dual specificity protein kinase YAK1 homolog; Dual specificity protein kinase that phosphorylates ANN1, ANN2 and CP29B at serine and threonine residues, and ANN1, ANN2 and ANN4 at tyrosine residues. May regulate the phosphorylation status of annexin proteins. Acts as positive regulator in abscisic acid (ABA)-mediated regulation of postgermination growth and drought response. May regulate the expression of ABA-responsive genes such as RD22, RD29A, LTI65/RD29B and RAB18. (956 aa) |
| | JMJ30 | Lysine-specific demethylase JMJ30; Histone demethylase that demethylates 'Lys-36' (H3K36me) of histone H3 with a specific activity for H3K36me3 and H3K36me2. No activity on H3K36me1. Involved in the control of flowering time by demethylating H3K36me2 at the FT locus and repressing its expression. Acts within the central clock. Works in concert with TOC1 to promote the morning-phased clock genes CCA1 and LHY which function as components of the central oscillator. (429 aa) |
| | Q8RWS0_ARATH | Chromatin-remodeling complex subunit. (124 aa) |
| | HDC1 | Zinc finger CCCH domain protein. (918 aa) |
| | Q8RWZ0_ARATH | Chaperone DnaJ-domain superfamily protein. (630 aa) |
| | UBN1 | Ubinuclein-1; May be required for replication-independent chromatin assembly; Belongs to the ubinuclein family. (684 aa) |
| | AGO4 | Protein argonaute 4; Together with RDM3, required for transcriptional gene silencing (TGS) by DNA methylation and repressive histone modifications (H3K9me2) of several chromatin loci. Component of the RISC complex that associate with the small interfering RNA (siRNA) pathway involved in direct cytosine methylation at endogenous DNA repeats. Forms a AGO4/NRPE1/siRNA complex in cajal body, facilitating its function in RNA-directed gene silencing of target loci. Required for CpNpG and asymmetric DNA methylation as well as histone H3 'Lys-9' methylation (H3K9me) at SUP and SN1 loci. May be [...] (924 aa) |
| | HUB1 | E3 ubiquitin-protein ligase BRE1-like 1; E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6. Required for the regulation of flowering time and defense against necrotrophic fungal pathogens. Involved in the control of seed dormancy and germination. Belongs to the BRE1 family. (878 aa) |
| | INO80 | Chromatin-remodeling ATPase INO80; ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (By similarity). Binds DNA (By similarity). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (By similarity). Positive regulator of homologous recombination, but not an essential component of homologous recombination. Not involved in the illegitimate repair pathway. Belongs to the SNF2/RAD54 helicase family. (1507 aa) |
| | T5J8.1 | Ras-induced vulval development antagonist protein. (422 aa) |
| | TRB1 | Telomere repeat-binding factor 1; Binds preferentially double-stranded telomeric repeats. (300 aa) |
| | K13P22.4 | DNA-binding bromodomain-containing protein. (916 aa) |
| | SWC4 | SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. (441 aa) |
| | SWI3A | SWI/SNF complex subunit SWI3A; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. (512 aa) |
| | HAG3 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Involved in tRNA wobble uridine modification. In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Promotes organs development by modulating cell division rate. Required for auxin distribution or signaling. Required for meristem cell cycle [...] (565 aa) |
| | ARP5 | Actin-related protein 5; Probable subunit of a chromatin-remodeling complex. Involved in DNA repair. Required for multicellular development of all organs. (724 aa) |
| | HDA2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (387 aa) |
| | LHP1 | Chromo domain-containing protein LHP1; Structural component of heterochromatin involved in gene repression, including several floral homeotic genes and FLT that regulates flowering time. Required for maintenance of vernalization- induced repression of FLC. As part of the PRC1-like complex, recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me), leading to epigenetic repression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling a [...] (445 aa) |
| | ASHR3 | Histone-lysine N-methyltransferase ASHR3; Histone methyltransferase (By similarity). Involved in stamen development; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (497 aa) |
| | F9N12.14 | Uncharacterized protein At1g63240. (548 aa) |
| | F16J13.140 | Uncharacterized protein At4g12070/F16J13_140. (483 aa) |
| | T8E24.3 | PAPA-1-like family protein / zinc finger (HIT type) family protein. (427 aa) |
| | HTA7 | Probable histone H2A.5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (150 aa) |
| | F10D13.28 | Appr-1-p processing enzyme family protein. (562 aa) |
| | ATX1-2 | Histone H3-lysine(4) N-trimethyltransferase ATX1; [Isoform 1]: Binds to the promoter and regulates the transcription of target genes, maintaining them in an active state; at promoters, required for TATA binding proteins (TBPs, e.g. TBP1 and TBP2) and RNA polymerase II (Pol II) recruitment, and, in a subsequent event, is recruited by a phosphorylated form of Pol II to the +300-bp region of transcribed sequences to trimethylates nucleosomes. Histone trimethyltransferase that trimethylates 'Lys-4' of histone H3 (H3K4me3); H3 'Lys-4' methylation represents a specific tag for epigenetic tra [...] (1062 aa) |
| | NSE4A | Non-structural maintenance of chromosomes element 4 homolog A; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids; Belongs to the NSE4 family. (403 aa) |
| | F13N6.4 | HIT zinc finger and PAPA-1-like domain-containing protein. (537 aa) |
| | HUB2 | E3 ubiquitin-protein ligase BRE1-like 2; E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6; Belongs to the BRE1 family. (900 aa) |
| | HTA9 | Probable histone H2A variant 3; Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A. May replace conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone cod [...] (134 aa) |
| | ARP4A | Actin-related protein 4A. (145 aa) |
| | ASF1A | Probable histone chaperone ASF1A; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (By similarity). While encoded by a region of the Arabidopsis thaliana genome that is homologous to the Brassica S-locus for self incompatibility, this protein may not play the same role in Arabidopsis thaliana; Belongs to the ASF1 family. (196 aa) |
| | HTB2 | Histone H2B.10; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa) |
| | UCH1 | Ubiquitin carboxyl-terminal hydrolase; Ubiquitin-protein hydrolase involved in the release of ubiquitin attached via both peptide and isopeptide linkages. Able to cleave 'Lys-48'-linked polyubiquitin chains. Involved in the direct or indirect regulation of AUX/IAA proteins stability (Probable). Acts as a linker between the TREX-2 complex and 26S proteasome. (334 aa) |
| | RLT2 | Homeobox-DDT domain protein RLT2; Transcriptional regulator required for the maintenance of the plant vegetative phase. In association with CHR11 or CHR17 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Involved in the transcriptional regulation of seed-specific gene expression. (1694 aa) |
| | HDA7 | Histone deacetylase 7; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. May be involved in flowering induction. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. (409 aa) |
| | TAF14B | Transcription initiation factor TFIID subunit 14b; Negative regulator of flowering controlling the H4K5 acetylation levels in the FLC and FT chromatin. Positively regulates FLC expression. Component of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of a NuA4 histone acetyltransferase complex which is involved in [...] (268 aa) |
| | SWC6 | SWR1 complex subunit 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Coodinates SWR1-C, FRI-C (FLC transcription activator complex), histone methyltransferase and general transcription factors. Represses flowering by positively regulating FLC and MAF4. Binds to the promoter region of FLC chromatin. (171 aa) |
| | HTA6 | Probable histone H2A.7; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (150 aa) |
| | MJE4.6 | Paired amphipathic helix (PAH2) superfamily protein. (155 aa) |
| | K9I9.20 | RuvB-like helicase; Belongs to the RuvB family. (469 aa) |
| | TRB2 | Telomere repeat-binding factor 2; Binds preferentially double-stranded telomeric repeats, but it can also bind to the single G-rich telomeric strand; Belongs to the histone H1/H5 family. SMH subfamily. (299 aa) |
| | HTR11 | Histone H3-like 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (139 aa) |
| | MLO10 | MLO-like protein 10; May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity). (569 aa) |
| | HDA6 | Histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Might remove acetyl residues only from specific targets, such as rDNA repeats or complex transgenes. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Required for rRNA gene silencing in nucleolar dominance. Plays a role in transgene silencing, but this e [...] (471 aa) |
| | RIN1 | RuvB-like protein 1; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. Has single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). (458 aa) |
| | CHC1-2 | SWI/SNF complex component SNF12 homolog; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology); Belongs to the SMARCD family. (534 aa) |
| | UVR8 | Ultraviolet-B receptor UVR8; UV-B specific signaling component that acts as UV-B photoreceptor and plays a key role in establishing UV-protective responses in plants. Upon UV-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, accumulates in the nucleus, interacts with the photomorphogenic repressor COP1 and regulates the expression of the transcription factor HY5 by associating with chromatin (through histone H2B binding) in the HY5 promoter region. UVR8 is involved in controlling aspects of leaf growth and morphogenesis in response to UV- B, is required for n [...] (440 aa) |
| | MHF15.6 | Zinc finger CCCH domain-containing protein 51. (378 aa) |
| | F3C3.3 | Alpha/beta-Hydrolases superfamily protein. (422 aa) |
| | T6J4.12 | Histone H3-like 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa) |
| | MGH3 | Histone H3-like 2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (137 aa) |
| | F17L21.5 | Paired amphipathic helix (PAH2) superfamily protein. (241 aa) |
| | T20K14.180 | Bromodomain transcription factor. (381 aa) |
| | K3M16.80 | Mediator of RNA polymerase II transcription subunit-like protein. (369 aa) |
| | F4P12.350 | Histone H2B.8; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (138 aa) |
| | F2G14.160 | Paired amphipathic helix (PAH2) superfamily protein. (87 aa) |
| | SNL2 | Paired amphipathic helix protein Sin3-like 2; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1367 aa) |
| | LARP6C | La-related protein 6C; Transcriptional regulator. (455 aa) |
| | Q9LK19_ARATH | Paired amphipathic helix Sin3-like protein. (374 aa) |
| | NRPD2 | DNA-directed RNA polymerases IV and V subunit 2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. A [...] (1172 aa) |
| | F2D10.15 | DNA-binding bromodomain-containing protein. (652 aa) |
| | HTB1 | Histone H2B.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (148 aa) |
| | F10A5.19 | Histone H3-like 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa) |
| | ARP9 | Actin-related protein 9. (596 aa) |
| | MBD6 | Methyl-CpG-binding domain-containing protein 6; Transcriptional regulator that binds CpG, CpNpN and CpNpG (N is A, T, or C) islands in promoters regardless the DNA methylation status. Plays probably a role in gene silencing. May associate with histone deacetylase proteins (HDAC). Required for nucleolar dominance that consist in the silencing of rRNA genes inherited from one progenitor in genetic hybrids. Recruited to rRNA genes in a DRM2- dependent manner. Maintains gene silencing by interacting with RNA binding proteins (e.g. NTF2, RPS2C, HDA6 and AGO4) and by regulating DNA methylati [...] (225 aa) |
| | MBD13 | Methyl-CpG-binding domain-containing protein 13; Probable transcriptional regulator. (746 aa) |
| | PYD1 | Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate and the reduction of thymine to 5,6-dihydrothymine (DHT). Involved in the recycling of nitrogen from nucleobases to general nitrogen metabolism; Belongs to the dihydropyrimidine dehydrogenase family. (426 aa) |
| | HIRA | Protein HIRA; Histone chaperone involved in maintining knox genes silencing throughout leaf development. Involved in heterochromatic and euchromatic gene silencing, especially upon salt stress. Involved in gene expression reprogramming during dedifferentiation probably by modifying histone H3.3 recruitment at the nucleolus. Contributes to maintenance of silencing of pericentromeric repeats and certain transposons ; Belongs to the WD repeat HIR1 family. (1024 aa) |
| | HDA17 | Histone deacetylase 17; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (158 aa) |
| | T24H18.80 | Histone H3-like 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (131 aa) |
| | T22P11.160 | Histone H2B.9; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (132 aa) |
| | HTA12 | Probable histone H2A.4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (153 aa) |
| | HTB11 | Histone H2B.7; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa) |
| | F16L2_40 | Nuclear factor kappa-B-binding-like protein. (1298 aa) |
| | F17I23.30 | At4g30630. (237 aa) |
| | HDA10 | Putative histone deacetylase 10; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (142 aa) |
| | TRB3 | Telomere repeat-binding factor 3; Binds preferentially double-stranded telomeric repeats, but it can also bind to the single G-rich telomeric strand. Belongs to the histone H1/H5 family. SMH subfamily. (295 aa) |
| | T16K5.180 | RuvB-like helicase; Belongs to the RuvB family. (473 aa) |
| | OBE1 | Protein OBERON 1; Probable transcription factor that acts together with OBE2 for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes such as WUS, PLT1 and PLT2 and of genes required for auxin responses. Promotes cell meristematic activity via the WUSCHEL-CLAVATA pathway. Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo. Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction w [...] (566 aa) |
| | F14P3.19 | Bromodomain transcription factor. (397 aa) |
| | GAMMA-H2AX | Probable histone H2AXb; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response [...] (142 aa) |
| | F28K20.20 | Bromodomain transcription factor. (277 aa) |
| | F26O13.140 | At3g51500. (116 aa) |
| | F11F8.5 | Histone H2B.5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa) |
| | FHA2 | FHA domain-containing protein FHA2; May play a role in the control of plant organ development and specifically in the regulation of stamen development. Does not show transactivation activity in yeast. (320 aa) |
| | T23G18.3 | Histone H2B.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (243 aa) |
| | MBD9 | Methyl-CpG-binding domain-containing protein 9; Probable transcriptional regulator that acts as a histone acetyltransferase. Mediates the acetylation of histone H3 and H4 of target loci (e.g. FLC). Involved in an auxin-independent regulation of shoot branching and flowering time. (2176 aa) |
| | T11P11.3 | Histone H2B.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (151 aa) |
| | HTA8 | Probable histone H2A variant 2; Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A. May replace conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone cod [...] (136 aa) |
| | DRD1 | Protein CHROMATIN REMODELING 35; Subunit of the chromatin-remodeling complex (DDR complex) that mediates RNA polymerases IV and V (Pol IV and Pol V) recruitment to chromatin. Cooperates with Pol IV and Pol V to regulates RNA- and RNAi- (RNA interference) directed non- CpG de novo DNA methylation on cytosine of genes targeted for silencing and enhancers, also known as siRNA-directed DNA methylation (RdDM), thus leading to epigenetic modification of the genome and promoting/maintaining heterochromatin. In collaboration with Pol V, mediates/maintains, in cis, methylation- associated self- [...] (888 aa) |
| | ACR10 | ACT domain-containing protein ACR10; May bind amino acids. (410 aa) |
| | RPA1A | Replication protein A 70 kDa DNA-binding subunit A; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Plays an essential role at later stages of meiotic recombination events required for the formation of class I crossovers. Is essential for normal progression through meiosis in pollen mother cells. Is involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses, but does not seem to be required for the repair of meiot [...] (640 aa) |
| | MBD5 | Methyl-CpG-binding domain-containing protein 5; Transcriptional regulator that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. In addition, binds specifically methylated m(5)CpNpN but not m(5)CpNpG (N is A, T or C). Plays probably a role in gene silencing. (182 aa) |
| | SNL1 | Paired amphipathic helix protein Sin3-like 1; Acts as a transcriptional repressor. An histone deacetylase (HDAC) activity is required for transcription repression. May play a role in telomere stability. (1372 aa) |
| | T21P5.12 | Mediator of RNA polymerase II transcription subunit-like protein. (354 aa) |
| | JMJ25 | Lysine-specific demethylase JMJ25; Histone demethylase that demethylates 'Lys-9' (H3K9me) of histone H3 with a specific activity for H3K9me2 and H3K9me1. No activity on H3K9me3, H3K4me3/2/1, H3K27me3/2/1 and H3K36me3/2/1. Involved in the control of several developmental processes by protecting genes from silencing. Demethylates H3K9me2 in the promoter regions of RDR2 and DCL3 and mediates the repression of ectopic non-CpG methylation at RDR2, DCL3 and APC13 loci. Protects also a large number of transcribed genes from non-CpG methylation. May regulate gene expression via a pathway invol [...] (1027 aa) |
| | REF6 | Lysine-specific demethylase REF6; Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me. Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay. Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli. Binds DNA via its four zinc fingers in a sequence- specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation. Involved in the regulation of flowering ti [...] (1360 aa) |
| | ATX4 | Histone-lysine N-methyltransferase ATX4; Histone methyltransferase. (1027 aa) |
| | F14N23.13 | Paired amphipathic helix Sin3-like protein. (77 aa) |
| | TAF8 | Transcription initiation factor TFIID subunit 8; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. (353 aa) |
| | WRKY19 | Probable WRKY transcription factor 19; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. May act also as a disease resistance protein with a serine/threonine-protein kinase activity (By similarity). (1895 aa) |
| | HTA4 | Histone H2A.8; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (118 aa) |
| | DDM1 | ATP-dependent DNA helicase DDM1; ATP-dependent DNA helicase that plays a role in formation, organization, stability and heritability of heterochromatin and thus regulates several physiological traits. Binds to the nucleosome and promotes chromatin remodeling in an ATP-dependent manner; induces nucleosome repositioning on a short DNA fragment, and, possibly, could be guided to target sites (including silent transposable elements) by small interfering RNAs (siRNAs). Can bind both free and nucleosomal DNA. Required for the heritable maintenance of genome integrity and transcriptional gene [...] (764 aa) |
| | MRE11 | Double-strand break repair protein MRE11; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (720 aa) |
| | SWI3C | SWI/SNF complex subunit SWI3C; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. (807 aa) |
| | SNL5 | Paired amphipathic helix protein Sin3-like 5; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1162 aa) |
| | SNL6 | Paired amphipathic helix protein Sin3-like 6; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1173 aa) |
| | NF-YB11 | Putative CCAAT-binding transcription factor subunit. (275 aa) |
| | MLH1 | DNA mismatch repair protein MLH1; Involved in DNA mismatch repair (MMR), correcting insertion- deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLbeta heterodimer, which probably forms a ternary complex with the MutSbeta heterodimer that initially recognizes the DNA mismatches. This complex is thought to be responsible for directing the downsteam MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in promoting meiotic crossing-over and i [...] (737 aa) |
| | F5O8.36 | Paired amphipathic helix (PAH2) superfamily protein. (241 aa) |
| | F3G5.26 | Histone H2B.4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (138 aa) |
| | YUP8H12R.20 | ARM repeat superfamily protein. (1341 aa) |
