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FTSHI1 FTSHI1 F4KH13_ARATH F4KH13_ARATH FTSHI4 FTSHI4 T14C9.180 T14C9.180 F16G20.120 F16G20.120 T4C21.1 T4C21.1 FTSHI5 FTSHI5 F13E7.15 F13E7.15 TIC236 TIC236 RBL10 RBL10 F4I765_ARATH F4I765_ARATH COR413IM2 COR413IM2 RE RE TIC32 TIC32 A0A1P8B0A1 A0A1P8B0A1 MEX1 MEX1 PAO PAO PLGG1 PLGG1 CHLH CHLH MSH12.19 MSH12.19 CPP1 CPP1 TIC40 TIC40 HP30-2 HP30-2 ARC6 ARC6 CLPC1 CLPC1 RER1 RER1 F13A11.2 F13A11.2 TIC TIC VTE1 VTE1 RER4 RER4 Q94C78_ARATH Q94C78_ARATH COR413IM1 COR413IM1 MXC17.8 MXC17.8 TGD2 TGD2 VTE3 VTE3 TIC55 TIC55 MDH MDH TOC75-3 TOC75-3 PAM71-HL PAM71-HL FAX3 FAX3 FAX1 FAX1 TIC110 TIC110 F21F14.40 F21F14.40 F5K20_210 F5K20_210 CRD1 CRD1 CAO-2 CAO-2 FTSH12 FTSH12 HP30-1 HP30-1 TIC21 TIC21 TIC100 TIC100 ABCI11 ABCI11 OBGL OBGL TGD1 TGD1 ABCI10 ABCI10 MTG13.11 MTG13.11 TIC62 TIC62 TIC20-I TIC20-I MQB2.4 MQB2.4 PHT4;4 PHT4;4 MCD1 MCD1 Q84MC3_ARATH Q84MC3_ARATH RBL11 RBL11 TIC56 TIC56 T20D1.20 T20D1.20 TOC34 TOC34 ACA1-2 ACA1-2 M370_ARATH M370_ARATH TIC214 TIC214 TIC20-II TIC20-II MGD1 MGD1 TOC159 TOC159 ARASP ARASP VIPP1 VIPP1 OEP37 OEP37 ARASP2 ARASP2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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FTSHI1Probable inactive ATP-dependent zinc metalloprotease FTSHI 1, chloroplastic; Functions in chloroplast biogenesis and chloroplast division. Required for plastid development during embryogenesis. Might be involved in chaperone functions or play a structural role in the thylakoid FtsH complex. In the N-terminal section; belongs to the AAA ATPase family. (946 aa)
F4KH13_ARATHMaltose excess-like protein. (261 aa)
FTSHI4Probable inactive ATP-dependent zinc metalloprotease FTSHI 4, chloroplastic; Functions in chloroplast biogenesis and chloroplast division. Required for plastid development during embryogenesis. Might be involved in chaperone functions or play a structural role in the thylakoid FtsH complex. (855 aa)
T14C9.180Rhomboid-related intramembrane serine protease family protein. (287 aa)
F16G20.120NAD(P)-binding Rossmann-fold superfamily protein. (333 aa)
T4C21.1Cytochrome P450 family protein. (404 aa)
FTSHI5Probable inactive ATP-dependent zinc metalloprotease FTSHI 5, chloroplastic; Required for plastid development during embryogenesis. Might be involved in chaperone functions or play a structural role in the thylakoid FtsH complex (Probable). In the N-terminal section; belongs to the AAA ATPase family. (1320 aa)
F13E7.15Low-density receptor-like protein. (168 aa)
TIC236Protein TIC236, chloroplastic; Part of the inner chloroplast membrane translocon complex (TIC) which associates with the outer chloroplast membrane translocon complex (TOC) and forms a supercomplex involved in protein precursor import into the chloroplast stroma. Required for the import of HSP93, TIC40 and RBCS protein precursors in the chloroplast stroma. Links the outer and inner membrane translocons of the chloroplast envelope. Belongs to the TamB family. (2166 aa)
RBL10RHOMBOID-like protein 10, chloroplastic; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Required for correct root growth, floral development, fertility and photoprotection. May be involved in TIC22 processing during its import and in AOS accumulation in the chloroplast membrane ; Belongs to the peptidase S54 family. (343 aa)
F4I765_ARATHHIT-type Zinc finger family protein. (644 aa)
COR413IM2Cold-regulated 413 inner membrane protein 2, chloroplastic. (226 aa)
REProtein RETICULATA, chloroplastic; May play a role in leaf development. Required for leaf mesophyll cell division in the early stages of leaf organogenesis. Acts in a developmental pathway that involves PPT1/CUE1 but does not include ASE2/DOV1 ; Belongs to the RETICULATA family. (432 aa)
TIC32Short-chain dehydrogenase TIC 32, chloroplastic; Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32, TIC 55 and TIC62. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
A0A1P8B0A1Ycf1 domain protein. (254 aa)
MEX1Maltose excess protein 1, chloroplastic; Probable maltose transporter. Essential for the conversion of starch to sucrose in leaves at night, probably via the export of maltose from the chloroplast. Required for root cap cells formation. (415 aa)
PAOPheophorbide a oxygenase, chloroplastic; Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with red chlorophyll catabolite reductase (RCCR). Creates the intermediate RCC through the opening of the porphyrin macrocycle by the introduction of one atom of molecular oxygen at the alpha-methine bridge. Seems to be specific for pheide a. Belongs to the chlorophyll catabolic enzymes (CCEs). (537 aa)
PLGG1Plastidal glycolate/glycerate translocator 1, chloroplastic; Glycolate/glycerate transporter required for photorespiration; Belongs to the CidB/LrgB family. (512 aa)
CHLHMagnesium-chelatase subunit ChlH, chloroplastic; Multifunctional protein involved in chlorophyll synthesis, plastid-to-nucleus retrograde signaling and abscisic acid (ABA) perception. In chlorophyll synthesis, catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step. In addition to its function in the Mg-chelatase enzyme, is required for the plastid-to- nucleus retrograde signaling. The plastid-to-nucleus signal plays an important rol [...] (1381 aa)
MSH12.19Uncharacterized protein family (UPF0114). (262 aa)
CPP1Protein CHAPERONE-LIKE PROTEIN OF POR1, chloroplastic; Essential protein required during embryogenesis. Exhibits holdase chaperone activity involved in the stabilization of NADPH:protochlorophyllide oxidoreductase (POR) proteins against photooxidative stress during POR proteins import into chloroplasts. Required for chloroplast biogenesis and development. When expressed in yeast, triggers mitochondria-mediated cell death associated with the loss of mitochondrial membrane potential. (258 aa)
TIC40Protein TIC 40, chloroplastic; Involved in protein precursor import into chloroplasts. Part of the motor complex consisting of a co-chaperone (TIC40) and a chaperone (HSP93) associated with the import channel (TIC110). Causes the release of bound transit peptides from TIC110 and stimulates ATP hydrolysis by HSP93. Involved in reinsertion of proteins from the chloroplast stroma into the inner membrane. (447 aa)
HP30-2Chloroplastic import inner membrane translocase subunit HP30-2; Together with HP30-1 and HP20, triggers the import and insertion of transit sequence-less multi-pass transmembrane proteins (e.g. CEQORH) into the chloroplastic inner membrane. Belongs to the Tim17/Tim22/Tim23 family. (259 aa)
ARC6Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic; Component of the plastid division machinery. Involved in the initiation of proplastid and plastid division (including chloroplasts, statoliths and leukoplasts). Promotes the assembly and/or stabilization of the plastid-dividing FtsZ ring, functioning as an antagonistic regulator of FtsZ dynamics against CDP1. Relays plastid division site position between stroma and outer surface via interactions with the stromal FtsZ ring and the outer membrane PDV2 that recruits cytoplasmic ARC5 ring. Required for plastid equatoria [...] (801 aa)
CLPC1Chaperone protein ClpC1, chloroplastic; Molecular chaperone that hydrolyzes ATP and is associated with the chloroplast protein import apparatus. May function as the motor for chloroplast protein translocation, as translocation requires ATP hydrolysis in the stroma. May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. Involved in the regulation of chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase (CAO) protein in response to the accumulation of chlorophyll b. Involved in leaf iron homeostasis. Belongs [...] (929 aa)
RER1Protein RETICULATA-RELATED 1, chloroplastic; May play a role in leaf development. Belongs to the RETICULATA family. (433 aa)
F13A11.2Inner membrane localized protein. (168 aa)
TICProtein TIME FOR COFFEE; Regulator of normal clock function. Acts in the mid to late night. Contributes to the amplitude of circadian clocks. May act on the transcriptional induction of LATE ELONGATED HYPOCOTYL (LHY). Inhibits MYC2 protein accumulation, acting as a negative factor in the JA- signaling pathway. (1550 aa)
VTE1Tocopherol cyclase, chloroplastic; Involved in the synthesis of both tocopherols and tocotrienols (vitamin E), which presumably protect photosynthetic complexes from oxidative stress. Catalyzes the conversion of 2-methyl- 6-phytyl-1,4-hydroquinone and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (DMPQ) to delta- and gamma-tocopherol respectively. Converts also 2,3- dimethyl-5-geranylgeranyl-1,4-hydroquinone (DMGQ) to gamma-tocotrienol. (488 aa)
RER4Protein RETICULATA-RELATED 4, chloroplastic; May play a role in leaf development. (386 aa)
Q94C78_ARATHDnaJ (DUF3353). (278 aa)
COR413IM1Cold-regulated 413 inner membrane protein 1, chloroplastic; Belongs to the Cold-regulated 413 protein family. (225 aa)
MXC17.8Plant/protein, putative (DUF3411). (521 aa)
TGD2Protein TRIGALACTOSYLDIACYLGLYCEROL 2, chloroplastic; Component of a phosphatidic acid/lipid transport complex in the chloroplast envelope. Specifically binds phosphatidic acid (PA). Involved in lipid transfer from the endoplasmic reticulum (ER) to plastids, and necessary for thylakoids formation. (381 aa)
VTE32-methyl-6-phytyl-1,4-hydroquinone methyltransferase, chloroplastic; Involved in a key methylation step in both tocopherols (vitamin E) and plastoquinone synthesis. Catalyzes the conversion of 2- methyl-6-phytyl-1,4-hydroquinone (MPBQ) to 2,3-dimethyl-6-phytyl-1,4- hydroquinone (DMPQ, a substrate for tocopherol cyclase), and 2-methyl- 6-solanyl-1,4-benzoquinone (MSBQ) to plastoquinone. (338 aa)
TIC55Protein TIC 55, chloroplastic; Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32, TIC 55 and TIC62. (539 aa)
MDHMalate dehydrogenase, chloroplastic; Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments (Probable). Plays a key role in the metabolism of dark chloroplasts and non-green plastids. Essential for embryo viability. Plays an essential role in heterotrophic metabolism in embryos, and autotrophic metabolism in photosynthetic tissues as well. (403 aa)
TOC75-3Protein TOC75-3, chloroplastic; Essential protein. Mediates the insertion of proteins targeted to the outer membrane of chloroplasts (By similarity). Required for the import of protein precursors into chloroplasts. Forms the voltage-dependent preprotein translocation channels (hydrophilic beta barrel) of the TOC complex in the chloroplastic outer membrane. (818 aa)
PAM71-HLProtein PAM71-homolog, chloroplastic; Probable chloroplast-localized Mn(2+)/H(+) and/or Ca(2+)/H(+) antiporter regulating Ca(2+), Mn(2+) and pH homeostasis. (359 aa)
FAX3Protein FATTY ACID EXPORT 3, chloroplastic; May be involved in free fatty acids export from the plastids. Belongs to the TMEM14 family. (335 aa)
FAX1Protein FATTY ACID EXPORT 1, chloroplastic; Mediates the export of free fatty acid from the plastids. Potentially prefers palmitic acid (C16:0) over oleic acid (C18:1) and stearic acid (C18:0). Not involved in fatty acid activation. Required for biogenesis of the outer pollen cell wall, in particular for the assembly of exine and pollen coat and for the release of ketone wax components. (226 aa)
TIC110Protein TIC110, chloroplastic; Involved in protein precursor import into chloroplasts. Forms a voltage-dependent cation-selective channel at the inner envelope of chloroplasts, which specifically responds to a transit peptide. Associates with both the precursor and mature forms of the preprotein. (1016 aa)
F21F14.40AT3g61870/F21F14_40. (272 aa)
F5K20_210Malate dehydrogenase-like protein. (108 aa)
CRD1Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME). (409 aa)
CAO-2Chlorophyllide a oxygenase, chloroplastic; Catalyzes a two-step oxygenase reaction involved in the synthesis of chlorophyll b. Acts specifically on the non-esterified chlorophyllide a and not on chlorophyll a. (536 aa)
FTSH12ATP-dependent zinc metalloprotease FTSH 12, chloroplastic; Probable ATP-dependent zinc metallopeptidase; In the N-terminal section; belongs to the AAA ATPase family. (1008 aa)
HP30-1Chloroplastic import inner membrane translocase subunit HP30-1; Together with HP30-2 and HP20, triggers the import and insertion of transit sequence-less multi-pass transmembrane proteins (e.g. CEQORH) into the chloroplastic inner membrane. Belongs to the Tim17/Tim22/Tim23 family. (261 aa)
TIC21Protein TIC 21, chloroplastic; Involved in chloroplast protein import across the inner envelope membrane. Acts also as a chloroplast permease regulating the iron transport and homeostasis. Involved in the uptake and sequestration of iron in plastids. (296 aa)
TIC100Protein TIC 100; Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein- conducting channel at the inner envelope. Plays an important role during embryogenesis and chloroplast biogenesis. (871 aa)
ABCI11ABC transporter I family member 11, chloroplastic. (278 aa)
OBGLGTP-binding protein OBGC, chloroplastic; GTP-binding protein involved in membrane biogenesis and protein synthesis in chloroplast. Functions in the biogenesis of thylakoid membrane and plastid ribosome during chloroplast development. May be involved in the vesicular traffic between the chloroplast inner envelope membrane and thylakoids. Possesses GTPase activity in vitro. (681 aa)
TGD1Protein TRIGALACTOSYLDIACYLGLYCEROL 1, chloroplastic; Required during embryogenesis. Permease involved in lipid transfer from the endoplasmic reticulum (ER) to plastids, and necessary for thylakoids formation. (350 aa)
ABCI10ABC transporter I family member 10; Belongs to the ABC transporter superfamily. ABCI family. (271 aa)
MTG13.11Low-density receptor-like protein. (168 aa)
TIC62Protein TIC 62, chloroplastic; Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32, TIC 55 and TIC62. Acts as a membrane anchor of LFNR1 and LFNR2. Has a NADPH-dependent dehydrogenase activity, but only after preincubation with lipids (By similarity). (641 aa)
TIC20-IProtein TIC 20-I, chloroplastic; Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein- conducting channel at the inner envelope. Seems to be specific for photosynthesis-related pre-proteins. Partially redundant with TIC20-IV, but not with TIC20-II or TIC20-V. (274 aa)
MQB2.4Integral membrane HPP family protein. (243 aa)
PHT4;4Ascorbate transporter, chloroplastic; Inorganic phosphate and probable anion transporter. Ascorbate transporter bridging the chloroplast envelope. Transports ascorbate from the cytosol into the chloroplast. Requires chloride ions and the presence of an electrochemical potential across the membrane for activity. Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family. (541 aa)
MCD1Protein MULTIPLE CHLOROPLAST DIVISION SITE 1; Required for chloroplast division. Regulates FtsZ ring positioning in chloroplasts. Determines the site of chloroplast division in concert with MIND1. Not directly involved in ring formation, but probably required for MIND1 localization to regulate FtsZ ring formation. (349 aa)
Q84MC3_ARATHIntegral membrane HPP family protein. (252 aa)
RBL11Rhomboid-like protein 11, chloroplastic; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. May be involved in TIC22 processing during its import. Belongs to the peptidase S54 family. (280 aa)
TIC56Protein TIC 56, chloroplastic; Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein- conducting channel at the inner envelope. (527 aa)
T20D1.20Tryptophan/tyrosine permease. (505 aa)
TOC34Translocase of chloroplast 34, chloroplastic; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast. (313 aa)
ACA1-2Calcium-transporting ATPase 1; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles. (1020 aa)
M370_ARATHUncharacterized mitochondrial protein AtMg00370; Belongs to the ycf1 family. (199 aa)
TIC214Protein TIC 214; Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein- conducting channel at the inner envelope. Belongs to the TIC214 family. (1786 aa)
TIC20-IIProtein TIC 20-II, chloroplastic; May be involved in protein precursor import into chloroplasts. Not redundant with TIC20-I, TIC20-IV or TIC20-V; Belongs to the Tic20 family. (208 aa)
MGD1Monogalactosyldiacylglycerol synthase 1, chloroplastic; Involved in the synthesis of the major structural component of photosynthetic membranes. Required for proper thylakoid membrane biogenesis. Does not discriminate between prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2-diacylglycerol species, but operates with some preference for the prokaryotic one. Belongs to the glycosyltransferase 28 family. (533 aa)
TOC159Translocase of chloroplast 159, chloroplastic; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Required for chloroplast biogenesis. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily. (1503 aa)
ARASPMembrane metalloprotease ARASP, chloroplastic; Metalloprotease essential for chloroplast and plant development. May be involved in regulated intramembrane proteolysis (RIP); Belongs to the peptidase M50A family. (447 aa)
VIPP1Membrane-associated protein VIPP1, chloroplastic; Required for plastid vesicle formation and thylakoid membrane biogenesis, but not for functional assembly of thylakoid protein complexes; Belongs to the PspA/IM30 family. (330 aa)
OEP37Outer envelope pore protein 37, chloroplastic; Voltage-dependent peptide-sensitive high conductance rectifying cation channel with a strong affinity for TIC32 that is imported into the chloroplast. Conductance is pH-dependent decreasing with decreasing pH values; Belongs to the plastid outer envelope porin OEP37 (TC 1.B.47) family. (343 aa)
ARASP2Probable membrane metalloprotease ARASP2, chloroplastic; Metalloprotease essential for chloroplast and plant development. May be involved in regulated intramembrane proteolysis (RIP); Belongs to the peptidase M50A family. (441 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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