STRINGSTRING
SFH1 SFH1 BCHA2 BCHA2 SFH9 SFH9 IREH1 IREH1 SFH8 SFH8 SPI SPI IRE3 IRE3 IRE4 IRE4 SFH4 SFH4 F7C8.40 F7C8.40 ANN1 ANN1 DTX42 DTX42 RABA4B RABA4B RABA4E RABA4E SFH7 SFH7 SFH10 SFH10 DTX43 DTX43 MTPC3 MTPC3 PAT04 PAT04 ALMT3 ALMT3 IRE IRE PI4KB1 PI4KB1 AGD1 AGD1 F26A9.21 F26A9.21 F2J7.20 F2J7.20 SAC7 SAC7 PATL4 PATL4 SFH12 SFH12 SFH3 SFH3 CNGC5 CNGC5 SFH5 SFH5 DTX44 DTX44 KIP KIP PAT03 PAT03 SFH13 SFH13 CNGC6 CNGC6 SFH14 SFH14 XI-K XI-K HDK HDK SFH11 SFH11 SFH2 SFH2 SFH6 SFH6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SFH1Phosphatidylinositol/phosphatidylcholine transfer protein SFH1; Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Plays a role in root hair tip elongation as a key regulator of polarized membrane trafficking. May promote the PtdIns(4,5)P2 synthesis and organization in root hair membrane. Belongs to the SFH family. (554 aa)
BCHA2BEACH domain-containing protein A2. (3527 aa)
SFH9Phosphatidylinositol/phosphatidylcholine transfer protein SFH9; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). Belongs to the SFH family. (579 aa)
IREH1Probable serine/threonine protein kinase IREH1; May be involved in root hair elongation. (1296 aa)
SFH8Phosphatidylinositol/phosphatidylcholine transfer protein SFH8; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). (633 aa)
SPIProtein SPIRRIG; Involved in cell morphogenesis. May have a function in membrane fusion or membrane composition. Required for salt stress tolerance. Regulates the salt stress-dependent post-transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress- regulated mRNAs. (3601 aa)
IRE3Probable serine/threonine protein kinase IRE3; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1235 aa)
IRE4Probable serine/threonine protein kinase IRE4. (1042 aa)
SFH4Phosphatidylinositol/phosphatidylcholine transfer protein SFH4; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). (608 aa)
F7C8.40Myosin. (372 aa)
ANN1Annexin D1; Has a peroxidase activity. May act in counteracting oxidative stress. May also mediate regulated, targeted secretion of Golgi-derived vesicles during seedling development. (317 aa)
DTX42Protein DETOXIFICATION 42; Citrate transporter critical for aluminum tolerance. Responsible for citrate exudation into the rhizosphere to protect roots from aluminum toxicity; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (515 aa)
RABA4BRas-related protein RABA4b; Regulator of membrane trafficking. May be required for secretion of cell wall components in cells; Belongs to the small GTPase superfamily. Rab family. (224 aa)
RABA4EPutative Ras-related protein RABA4e; Belongs to the small GTPase superfamily. Rab family. (176 aa)
SFH7Phosphatidylinositol/phosphatidylcholine transfer protein SFH7; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). Belongs to the SFH family. (547 aa)
SFH10Phosphatidylinositol/phosphatidylcholine transfer protein SFH10; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). Belongs to the SFH family. (558 aa)
DTX43Protein DETOXIFICATION 43; Citrate transporter responsible for loading citrate into xylem tissues, which helps facilitate iron transport to shoots. Mediates the citrate release in the apoplastic spaces during plant development allowing iron nutrition between symplastically disconnected tissues. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (526 aa)
MTPC3Putative metal tolerance protein C3; Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (411 aa)
PAT04Probable protein S-acyltransferase 4; Palmitoyl acyltransferase. (477 aa)
ALMT3Putative aluminum-activated malate transporter 3; Malate transporter; Belongs to the aromatic acid exporter (TC 2.A.85) family. (581 aa)
IREProbable serine/threonine protein kinase IRE; Modulates root tip growth. May play a common role in the tip growth of plant cells. (1168 aa)
PI4KB1Phosphatidylinositol 4-kinase beta 1; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5- trisphosphate. Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB2, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB2 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway. (1121 aa)
AGD1ADP-ribosylation factor GTPase-activating protein AGD1; Probable GTPase-activating protein (By similarity). Regulator of membrane trafficking. Required for maintaining a straight growth of root hairs. (828 aa)
F26A9.21ARM repeat superfamily protein. (909 aa)
F2J7.20GDT1-like protein 4. (230 aa)
SAC7Phosphoinositide phosphatase SAC7; Phosphoinositide phosphatase that preferentially hydrolyzes PtdIns(4)P. Regulates the accumulation of PtdIns(4)P on membrane compartments at the tips of growing root hairs leading to proper root hair development. (597 aa)
PATL4Patellin-4; Carrier protein that may be involved in membrane-trafficking events associated with cell plate formation during cytokinesis. Binds to some hydrophobic molecules such as phosphoinositides and promotes their transfer between the different cellular sites (By similarity). (540 aa)
SFH12Phosphatidylinositol/phosphatidylcholine transfer protein SFH12; Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro; Belongs to the SFH family. (543 aa)
SFH3Phosphatidylinositol/phosphatidylcholine transfer protein SFH3; Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. (548 aa)
CNGC5Probable cyclic nucleotide-gated ion channel 5; Probable cyclic nucleotide-gated ion channel; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. (717 aa)
SFH5Phosphatidylinositol/phosphatidylcholine transfer protein SFH5; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). (612 aa)
DTX44Protein DETOXIFICATION 44, chloroplastic; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (521 aa)
KIPProtein KINKY POLLEN; May be involved in membrane trafficking (By similarity). Required for tip growth in pollen tubes and root hairs. Belongs to the SABRE family. (2587 aa)
PAT03Probable protein S-acyltransferase 3; Palmitoyl acyltransferase. (413 aa)
SFH13Phosphatidylinositol/phosphatidylcholine transfer protein SFH13; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). (625 aa)
CNGC6Probable cyclic nucleotide-gated ion channel 6; Probable cyclic nucleotide-gated ion channel; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. (747 aa)
SFH14Phosphatidylinositol/phosphatidylcholine transfer protein SFH14; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). Belongs to the SFH family. (577 aa)
XI-KMyosin-17; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in the tip growth of root hair cells and in the elongation of trichome stalk and branches. Plays a major role in trafficking of Golgi stacks, mitochondria and peroxisomes during root hair development. Acts as the primary co [...] (1531 aa)
HDKMyosin. (556 aa)
SFH11Phosphatidylinositol/phosphatidylcholine transfer protein SFH11; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). Belongs to the SFH family. (376 aa)
SFH2Phosphatidylinositol/phosphatidylcholine transfer protein SFH2; Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. (554 aa)
SFH6Phosphatidylinositol/phosphatidylcholine transfer protein SFH6; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity). (614 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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