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MPK2 MPK2 A0A178VGS0 A0A178VGS0 STY13 STY13 CYTB5-C CYTB5-C UNC UNC F14M19.70 F14M19.70 EDS1 EDS1 VPS29 VPS29 TIR TIR TATC TATC RLP3 RLP3 RLP2 RLP2 GATA6 GATA6 F24M12.290 F24M12.290 PAD4 PAD4 PDE247 PDE247 GATA14 GATA14 ISA3 ISA3 F17I23.340 F17I23.340 DCAF1 DCAF1 F6E21.90 F6E21.90 PELPK1 PELPK1 PELPK2 PELPK2 UCNL UCNL BAM1-2 BAM1-2 GFAT GFAT GEX3 GEX3 F1N18.9 F1N18.9 MO3 MO3 Q9FKL1_ARATH Q9FKL1_ARATH GATA5 GATA5 IAN1 IAN1 LSM3B LSM3B BAK1 BAK1 T30A10.100 T30A10.100 F1C12.70 F1C12.70 AMY3 AMY3 UEV1A UEV1A AMY1 AMY1 T30A10.2 T30A10.2 AMY2 AMY2 GATA3 GATA3 F24C20.8 F24C20.8 GLR3.4 GLR3.4 T1G16.40 T1G16.40 Q5XF13_ARATH Q5XF13_ARATH CNX1-2 CNX1-2 MPK7 MPK7 MPK1 MPK1 F2K13.70 F2K13.70 HST HST LA2 LA2 LON1 LON1 KAT3 KAT3 BAM5 BAM5 GPA1 GPA1 MO2 MO2 GATA7 GATA7 GATA4 GATA4 GATA2 GATA2 MPK14 MPK14 FAB2 FAB2 GLR2.1 GLR2.1 CAND8 CAND8 F14A1.10 F14A1.10 F4J381_ARATH F4J381_ARATH F22D22.11 F22D22.11 F19C24.2 F19C24.2 RANBPM RANBPM T21F11.13 T21F11.13 F19C24.23 F19C24.23 VPS35C VPS35C ATIM ATIM T10D10.19 T10D10.19 A0A1I9LME3 A0A1I9LME3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MPK2Mitogen-activated protein kinase 2. (376 aa)
A0A178VGS0Transmembrane protein. (264 aa)
STY13Serine/threonine-protein kinase STY13; Serine/threonine protein kinase that phosphorylates proteins on serine, threonine and tyrosine residues. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (411 aa)
CYTB5-CCytochrome B5 isoform C; Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases. (132 aa)
UNCSerine/threonine-protein kinase UCN; Regulates planar ovule integument development by suppressing aberrantly oriented growth. Maintains planar growth of integuments by repressing the developmental regulator and transcription factor KAN4 which is involved in the control of early integument growth and polarity. Restricts growth in stamen filaments, petals, and cotyledons. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (404 aa)
F14M19.70Putative pathogenesis-related protein; Belongs to the CRISP family. (210 aa)
EDS1Protein EDS1; Positive regulator of basal resistance and of effector- triggered immunity specifically mediated by TIR-NB-LRR (TNL) resistance proteins. Disruption by bacterial effector of EDS1-TIR-NB-LRR resistance protein interactions constitutes the first step in resistance activation. Acts redundantly with salicylic acid to regulate resistance gene-mediated signaling. Triggers early plant defenses and hypersensitive response independently of PAD4, and then recruits PAD4 to potentiate plant defenses through the accumulation of salicylic acid. Nuclear localization is essential for bas [...] (623 aa)
VPS29Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Required for the auxin-carrier protein PIN2 sorting to the lytic vacuolar pathway and the PIN1 recycling to the plasma membrane. Also involved in the efficient sorting of seed storage proteins globulin 12S and albumin 2S. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (190 aa)
TIRToll/interleukin-1 receptor-like protein; Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth (By similarity). (176 aa)
TATCSec-independent protein translocase protein TATC, chloroplastic; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation. (340 aa)
RLP3Receptor-like protein 3; Involved in the perception of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristems maintenance (By similarity). Contributes, with WAKL22/RFO1, to resistance to F.oxysporum (f.) matthioli in cv. Columbia relative to cv. Ty-0 ; Belongs to the RLP family. (756 aa)
RLP2Receptor-like protein 2; Involved in the perception of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristems maintenance. Belongs to the RLP family. (729 aa)
GATA6GATA transcription factor 6; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity). Belongs to the type IV zinc-finger family. Class A subfamily. (312 aa)
F24M12.290Senescence/dehydration-associated protein At3g51250. (463 aa)
PAD4Lipase-like PAD4; Probable lipase required downstream of MPK4 for accumulation of the plant defense-potentiating molecule, salicylic acid, thus contributing to the plant innate immunity against invasive biotrophic pathogens and to defense mechanisms upon recognition of microbe- associated molecular patterns (MAMPs). Participates in the regulation of various molecular and physiological processes that influence fitness. Together with SG101, required for programmed cell death (PCD) triggered by NBS-LRR resistance proteins (e.g. RPS4, RPW8.1 and RPW8.2) in response to the fungal toxin fumo [...] (541 aa)
PDE247Pentatricopeptide repeat-containing protein At1g05750, chloroplastic. (500 aa)
GATA14GATA transcription factor 14; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity). Belongs to the type IV zinc-finger family. Class A subfamily. (204 aa)
ISA3Isoamylase 3, chloroplastic; Involved in starch catabolism. ISA3 removes different branches than ISA1-ISA2, namely short chains that prevent amylopectin crystallization. May be the debranching enzyme required to assist beta- amylases for starch degradation in leaves at night. Belongs to the glycosyl hydrolase 13 family. (764 aa)
F17I23.340PR-1-like protein; Belongs to the CRISP family. (161 aa)
DCAF1DDB1- and CUL4-associated factor homolog 1; Component of the CUL4-RBX1-DDB1-DCAF1 E3 ubiquitin-protein ligase complex, DCAF1 may function as the substrate recognition module within this complex. Appears to be required for plant embryogenesis and to affect several other developmental processes including leaf, shoot, and flower development; Belongs to the VPRBP/DCAF1 family. (1883 aa)
F6E21.90Protein kinase superfamily protein. (412 aa)
PELPK1Protein PELPK1; Positive regulator of germination and plant growth. (370 aa)
PELPK2Protein PELPK2. (130 aa)
UCNLSerine/threonine-protein kinase UCNL; Regulates planar ovule integument development. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (408 aa)
BAM1-2Beta-amylase 1, chloroplastic; Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active on phosphorylated glucan. Interacts directly with starch or other alpha-1,4-glucan. (575 aa)
GFATPutative glucosamine-fructose-6-phosphate aminotransferase. (677 aa)
GEX3Protein GAMETE EXPRESSED 3; Required for micropylar pollen tube guidance. Plays a role during early embryo patterning. (641 aa)
F1N18.9Putative glycine--tRNA ligase, cytoplasmic; Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs (By similarity); Belongs to the class-II aminoacyl-tRNA synthetase family. (463 aa)
MO3Monooxygenase 3. (406 aa)
Q9FKL1_ARATHSimilarity to pathogenesis-related protein; Belongs to the CRISP family. (207 aa)
GATA5GATA transcription factor 5; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity). Belongs to the type IV zinc-finger family. Class A subfamily. (339 aa)
IAN1Immune-associated nucleotide-binding protein 1. (225 aa)
LSM3BSm-like protein LSM3B; Component of LSM protein complexes, which are involved in RNA processing. Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay. The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development- related transcripts. Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs. LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected developme [...] (98 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
T30A10.100SPla/RYanodine receptor (SPRY) domain-containing protein. (447 aa)
F1C12.70Excitatory amino acid transporter. (81 aa)
AMY3Alpha-amylase 3, chloroplastic; Possesses endoamylolytic activity in vitro, but seems not required for breakdown of transitory starch in leaves. May be involved in the determination of the final structure of glucans by shortening long linear phospho-oligosaccharides in the chloroplast stroma. Can act on both soluble and insoluble glucan substrates to release small linear and branched malto-oligosaccharides. Works synergistically with beta-amylase toward efficient starch degradation. Has activity against p-nitrophenyl maltoheptaoside (BPNP-G7), amylopectin and beta-limit dextrin. Involv [...] (887 aa)
UEV1AUbiquitin-conjugating enzyme E2 variant 1A; Has no ubiquitin ligase activity on its own. The heterodimer with UBC catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. May play a role in the control of progress through the cell cycle and differentiation. Probably not involved in the error-free DNA repair. (158 aa)
AMY1Alpha-amylase 1; Possesses alpha-amylase activity in vitro, but seems not required for breakdown of transitory starch in leaves. (423 aa)
T30A10.2SPla/RYanodine receptor (SPRY) domain-containing protein. (397 aa)
AMY2Probable alpha-amylase 2; Probable alpha-amylase that does not seem to be required for breakdown of transitory starch in leaves. (413 aa)
GATA3GATA transcription factor 3; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes. Belongs to the type IV zinc-finger family. Class A subfamily. (269 aa)
F24C20.8Plasma membrane fusion protein. (541 aa)
GLR3.4Glutamate receptor 3.4; Glutamate-gated receptor that probably acts as non-selective cation channel, at least in hypocotyls. Can be triggered by Ala, Asn, Gly, Ser and, to a lower extent, Cys and Glu. May be involved in light- signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Plays an important role in the calcium-based fast transmission of environmental stress. (959 aa)
T1G16.40T-box protein. (335 aa)
Q5XF13_ARATHTransmembrane protein. (260 aa)
CNX1-2Molybdopterin biosynthesis protein CNX1; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released; In the N-terminal section; belongs to the MoaB/Mog family. (670 aa)
MPK7Mitogen-activated protein kinase 7; MKK3-MPK7 module acts as a positive regulator of PR1 gene expression; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
MPK1Mitogen-activated protein kinase 1. (370 aa)
F2K13.70Fasciclin-like arabinogalactan family protein. (256 aa)
HSTHomogentisate solanesyltransferase, chloroplastic; Involved in the synthesis of plastoquinone-9. Can use both homogentisic acid and 2,5-dihydroxyphenylacetic acid gamma-lactone as prenyl acceptors, and solanesyl diphosphate > farnesyl diphosphate > geranylgeranyl diphosphate >> phytyl diphosphate as prenyl donors. Do not catalyze the decardoxylation of homogentisate uncoupled from prenylation; Belongs to the UbiA prenyltransferase family. (386 aa)
LA2La protein 2; Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. (399 aa)
LON1Lon protease homolog 1, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (940 aa)
KAT3Potassium channel KAT3; Probable modulatory (alpha) subunit of inward-rectifying potassium channels. Could mediate potassium uptake from the soil solution by plant roots in association with AKT1. (662 aa)
BAM5Beta-amylase 5; Beta-amylase activity. Major cytosolic beta-amylase isoform in rosette leaves and inflorescences stems. (498 aa)
GPA1Guanine nucleotide-binding protein alpha-1 subunit; Exhibits a fast rate of basal nucleotide exchange. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Together with GCR1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate (IP(3)) as a second messenger. Promotes abscisic acid (ABA) responses in guard cells. But, together with GCR1 and GB1, acts as a negative regulator of ABA during seed ge [...] (383 aa)
MO2Monooxygenase 2. (407 aa)
GATA7GATA transcription factor 7; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes (By similarity). Belongs to the type IV zinc-finger family. Class A subfamily. (238 aa)
GATA4GATA transcription factor 4; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes. (240 aa)
GATA2GATA transcription factor 2; Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes. (264 aa)
MPK14Mitogen-activated protein kinase 14; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
FAB2Stearoyl-[acyl-carrier-protein] 9-desaturase 7, chloroplastic; Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain. Required for the activation of certain jasmonic acid (JA)-mediated responses and the repression of the salicylic acid (SA) signaling pathway. Belongs to the fatty acid desaturase type 2 family. (401 aa)
GLR2.1Glutamate receptor 2.1; Glutamate-gated receptor that probably acts as non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. (901 aa)
CAND8Protein CANDIDATE G-PROTEIN COUPLED RECEPTOR 8; G-protein coupled receptor. Plays a role in plants and microbes interactions (By similarity). Belongs to the UPF0359 family. (297 aa)
F14A1.10Putative acyl-activating enzyme 19; Belongs to the ATP-dependent AMP-binding enzyme family. (1040 aa)
F4J381_ARATHFG-GAP repeat-containing protein. (698 aa)
F22D22.11Transmembrane receptor. (353 aa)
F19C24.2Leucine-rich repeat protein kinase family protein. (884 aa)
RANBPMRan-binding protein M homolog. (467 aa)
T21F11.13Envelope glycoprotein B. (538 aa)
F19C24.23Probable LRR receptor-like serine/threonine-protein kinase At1g51820; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (885 aa)
VPS35CVacuolar protein sorting-associated protein 35C; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins (By similarity). The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (790 aa)
ATIMTimeless family protein. (1163 aa)
T10D10.19NagB/RpiA/CoA transferase-like superfamily protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (409 aa)
A0A1I9LME3Lon protease-like protein. (134 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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