STRINGSTRING
ATG7 ATG7 RBL18 RBL18 ATG9 ATG9 ATG16 ATG16 ATG3 ATG3 T16B12.6 T16B12.6 F4IL92_ARATH F4IL92_ARATH F2H15.22 F2H15.22 F3N23.33 F3N23.33 MWD22.9 MWD22.9 RBL20 RBL20
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
ATG7Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process. Involved in the degradation of damaged peroxisomes. Involved in the non-selective degradation of chlorophylls and photosynthetic proteins during stress-induced leaf yellowing. (697 aa)
RBL18Rhomboid-like protein 18; Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis; Belongs to the peptidase S54 family. (287 aa)
ATG9Autophagy-related protein 9; Required for autophagy that plays an essential role in plant nutrient recycling. Contributes to efficient autophagic flux, especially in early autophagic process prior to the fusion of the autophagosome with the vacuole. Belongs to the ATG9 family. (866 aa)
ATG16Autophagy-related protein 16; May play a role in autophagy. (509 aa)
ATG3Autophagy-related protein 3; E2 conjugating enzyme responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt); Belongs to the ATG3 family. (313 aa)
T16B12.6At2g31130/T16B12.6. (419 aa)
F4IL92_ARATHMucin. (170 aa)
F2H15.22Transmembrane protein. (263 aa)
F3N23.33F3N23.33 protein. (646 aa)
MWD22.9Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein. (531 aa)
RBL20Rhomboid-like protein 20; Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis; Belongs to the peptidase S54 family. (293 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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