STRINGSTRING
F4IWG7_ARATH F4IWG7_ARATH F6A14.25 F6A14.25 F4JN57_ARATH F4JN57_ARATH T18B16.130 T18B16.130 hus1 hus1 RPA2B RPA2B FBL17 FBL17 SMC6B SMC6B SMC6A SMC6A F12E4.210 F12E4.210 F17C15.170 F17C15.170 AT4G37420 AT4G37420 MRE11 MRE11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F4IWG7_ARATHZinc finger (C3HC4-type RING finger) family protein. (913 aa)
F6A14.25Zinc finger (C3HC4-type RING finger) family protein. (491 aa)
F4JN57_ARATHDDE family endonuclease. (527 aa)
T18B16.130Transglutaminase family protein. (453 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (319 aa)
RPA2BReplication protein A 32 kDa subunit B; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Required fo cell division in meristems. Involved in the maintenance of transcriptional epigenetic gene silencing (TGS) at specific loci (including some transposons) by regulating histone H3 acetylation, 'Lys-4' and 'Lys-9' methylation (By similarity). (278 aa)
FBL17F-box/LRR-repeat protein 17; Essential protein for male fertility. Component of the SCF(ASK-cullin-F-box) E3 ubiquitin ligase complex SCF(FBL17), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Enables the switch in cell cycle control leading to male germ cell lineage formation from microspores after meiosis. Targets CDKA-1 inhibitors the degradation specifically in male germ cells (e.g. KRP6 and KRP7) and thus enables CDKA-1 activation and germ cell S-phase progression. Promotes twin sperm cell production and double fertilization. (593 aa)
SMC6BStructural maintenance of chromosomes protein 6B; Core component of the SMC5-SMC6 complex that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (1057 aa)
SMC6AStructural maintenance of chromosomes protein 6A; Core component of the SMC5-SMC6 complex that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids; Belongs to the SMC family. SMC6 subfamily. (1058 aa)
F12E4.210Transducin/WD40 repeat-like superfamily protein. (630 aa)
F17C15.170E3 ubiquitin-protein ligase. (169 aa)
AT4G37420Glycosyltransferase family 92 protein; Belongs to the glycosyltransferase 92 family. (588 aa)
MRE11Double-strand break repair protein MRE11; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (720 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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