(9 nodes) Inositol monophosphatase-like network (Arabidopsis thaliana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C17L7.10	Putative PAP-specific phosphatase, mitochondrial; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the inositol monophosphatase superfamily. (397 aa)
	IMPL1	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P). (371 aa)
	SAL3	Probable SAL3 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Is also able to hydrolyze inositol 1,4- bisphosphate; Belongs to the inositol monophosphatase superfamily. (357 aa)
	SAL2	SAL2 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation. Is also able to hydrolyze inositol 1,4-bisphosphate. (347 aa)
	AHL	PAP-specific phosphatase HAL2-like; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation; Belongs to the inositol monophosphatase superfamily. (373 aa)
	SAL4	Probable SAL4 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Is also able to hydrolyze inositol 1,4- bisphosphate. (345 aa)
	HISN7	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily. (346 aa)
	SAL1	SAL1 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4- trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate (IP3) turnover. Is [...] (353 aa)
	VTC4	Inositol-phosphate phosphatase; Phosphatase acting on L-galactose 1-phosphate (L-Gal 1-P), D- myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D- Ins 1-P). Can also use beta-glycerophosphate (glycerol 2-P) and, to a lesser extent, D-galactose 1-phosphate (D-Gal 1-P), alpha-D-glucose 1- phosphate (a-D-Glc 1-P), D-manitol 1-phosphate and adenosine 2'- monophosphate as substrates. No activity with D-fructose 1-phosphate (D-Fru 1-P), fructose 1,6-bisphosphate (Fru 1,6-bisP), D-glucose 6- phosphate (D-Glc 6-P), D-alpha-glycerophosphate (glycerol 3-P), D- sorbitol 6-phospha [...] (271 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHL	HISN7	Q38945	Q6NPM8	PAP-specific phosphatase HAL2-like; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation; Belongs to the inositol monophosphatase superfamily.	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	0.402
AHL	IMPL1	Q38945	Q94F00	PAP-specific phosphatase HAL2-like; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation; Belongs to the inositol monophosphatase superfamily.	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	0.412
AHL	VTC4	Q38945	Q9M8S8	PAP-specific phosphatase HAL2-like; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation; Belongs to the inositol monophosphatase superfamily.	Inositol-phosphate phosphatase; Phosphatase acting on L-galactose 1-phosphate (L-Gal 1-P), D- myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D- Ins 1-P). Can also use beta-glycerophosphate (glycerol 2-P) and, to a lesser extent, D-galactose 1-phosphate (D-Gal 1-P), alpha-D-glucose 1- phosphate (a-D-Glc 1-P), D-manitol 1-phosphate and adenosine 2'- monophosphate as substrates. No activity with D-fructose 1-phosphate (D-Fru 1-P), fructose 1,6-bisphosphate (Fru 1,6-bisP), D-glucose 6- phosphate (D-Glc 6-P), D-alpha-glycerophosphate (glycerol 3-P), D- sorbitol 6-phospha [...]	0.402
C17L7.10	HISN7	Q9M0Y6	Q6NPM8	Putative PAP-specific phosphatase, mitochondrial; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the inositol monophosphatase superfamily.	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	0.402
C17L7.10	IMPL1	Q9M0Y6	Q94F00	Putative PAP-specific phosphatase, mitochondrial; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the inositol monophosphatase superfamily.	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	0.430
C17L7.10	VTC4	Q9M0Y6	Q9M8S8	Putative PAP-specific phosphatase, mitochondrial; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the inositol monophosphatase superfamily.	Inositol-phosphate phosphatase; Phosphatase acting on L-galactose 1-phosphate (L-Gal 1-P), D- myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D- Ins 1-P). Can also use beta-glycerophosphate (glycerol 2-P) and, to a lesser extent, D-galactose 1-phosphate (D-Gal 1-P), alpha-D-glucose 1- phosphate (a-D-Glc 1-P), D-manitol 1-phosphate and adenosine 2'- monophosphate as substrates. No activity with D-fructose 1-phosphate (D-Fru 1-P), fructose 1,6-bisphosphate (Fru 1,6-bisP), D-glucose 6- phosphate (D-Glc 6-P), D-alpha-glycerophosphate (glycerol 3-P), D- sorbitol 6-phospha [...]	0.414
HISN7	AHL	Q6NPM8	Q38945	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	PAP-specific phosphatase HAL2-like; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation; Belongs to the inositol monophosphatase superfamily.	0.402
HISN7	C17L7.10	Q6NPM8	Q9M0Y6	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	Putative PAP-specific phosphatase, mitochondrial; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the inositol monophosphatase superfamily.	0.402
HISN7	IMPL1	Q6NPM8	Q94F00	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	0.943
HISN7	SAL1	Q6NPM8	Q42546	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	SAL1 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4- trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate (IP3) turnover. Is [...]	0.970
HISN7	SAL2	Q6NPM8	O49623	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	SAL2 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation. Is also able to hydrolyze inositol 1,4-bisphosphate.	0.954
HISN7	SAL3	Q6NPM8	Q8GY63	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	Probable SAL3 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Is also able to hydrolyze inositol 1,4- bisphosphate; Belongs to the inositol monophosphatase superfamily.	0.953
HISN7	SAL4	Q6NPM8	Q84VY5	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	Probable SAL4 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Is also able to hydrolyze inositol 1,4- bisphosphate.	0.955
HISN7	VTC4	Q6NPM8	Q9M8S8	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	Inositol-phosphate phosphatase; Phosphatase acting on L-galactose 1-phosphate (L-Gal 1-P), D- myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D- Ins 1-P). Can also use beta-glycerophosphate (glycerol 2-P) and, to a lesser extent, D-galactose 1-phosphate (D-Gal 1-P), alpha-D-glucose 1- phosphate (a-D-Glc 1-P), D-manitol 1-phosphate and adenosine 2'- monophosphate as substrates. No activity with D-fructose 1-phosphate (D-Fru 1-P), fructose 1,6-bisphosphate (Fru 1,6-bisP), D-glucose 6- phosphate (D-Glc 6-P), D-alpha-glycerophosphate (glycerol 3-P), D- sorbitol 6-phospha [...]	0.931
IMPL1	AHL	Q94F00	Q38945	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	PAP-specific phosphatase HAL2-like; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation; Belongs to the inositol monophosphatase superfamily.	0.412
IMPL1	C17L7.10	Q94F00	Q9M0Y6	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	Putative PAP-specific phosphatase, mitochondrial; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP; Belongs to the inositol monophosphatase superfamily.	0.430
IMPL1	HISN7	Q94F00	Q6NPM8	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	Bifunctional phosphatase IMPL2, chloroplastic; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P). Belongs to the inositol monophosphatase superfamily.	0.943
IMPL1	SAL1	Q94F00	Q42546	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	SAL1 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4- trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate (IP3) turnover. Is [...]	0.986
IMPL1	SAL2	Q94F00	O49623	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	SAL2 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation. Is also able to hydrolyze inositol 1,4-bisphosphate.	0.970
IMPL1	SAL3	Q94F00	Q8GY63	Phosphatase IMPL1, chloroplastic; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P).	Probable SAL3 phosphatase; Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Is also able to hydrolyze inositol 1,4- bisphosphate; Belongs to the inositol monophosphatase superfamily.	0.966