(14 nodes) Pyruvate kinase network (Arabidopsis thaliana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q94KE3_ARATH	Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
	PKP3	Plastidial pyruvate kinase 3, chloroplastic; Required for plastidial pyruvate kinase activity. (571 aa)
	M3E9.180	Probable pyruvate kinase, cytosolic isozyme; Key regulatory enzyme of the glycolytic pathway that catalyzes the final step of glycolysis, converting ADP and phosphoenolpyruvate (PEP) to ATP and pyruvate by essentially irreversible transphosphorylation. (497 aa)
	F1I16_220	Pyruvate kinase; Belongs to the pyruvate kinase family. (492 aa)
	Q9LU95_ARATH	Pyruvate kinase; Belongs to the pyruvate kinase family. (497 aa)
	PKP1	Plastidial pyruvate kinase 1, chloroplastic; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. (596 aa)
	MAH20.13	Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
	MCD7.8	Pyruvate kinase; Belongs to the pyruvate kinase family. (498 aa)
	F1I16_60	Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
	PKP2	Plastidial pyruvate kinase 2; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. (579 aa)
	MBK5.16	Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
	T11I18.16	Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
	F1O11.21	Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
	PKP4	Plastidial pyruvate kinase 4, chloroplastic. (710 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F1O11.21	MCD7.8	Q9SJQ0	Q9FM97	Pyruvate kinase; Belongs to the pyruvate kinase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.498
MCD7.8	F1O11.21	Q9FM97	Q9SJQ0	Pyruvate kinase; Belongs to the pyruvate kinase family.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.498
PKP1	PKP2	Q9LIK0	Q9FLW9	Plastidial pyruvate kinase 1, chloroplastic; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination.	Plastidial pyruvate kinase 2; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination.	0.418
PKP2	PKP1	Q9FLW9	Q9LIK0	Plastidial pyruvate kinase 2; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination.	Plastidial pyruvate kinase 1, chloroplastic; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination.	0.418