STRINGSTRING
SLD2 SLD2 SLD1 SLD1 DES-1-LIKE DES-1-LIKE ADS2 ADS2 ADS3.2 ADS3.2 T21E18.14 T21E18.14 T21E18.15 T21E18.15 ADS4 ADS4 T2D23.6 T2D23.6 T21E18.17 T21E18.17 ADS3 ADS3 FAD3 FAD3 FAD8 FAD8 FAD2 FAD2 FAD6 FAD6 FAD7 FAD7 ADS1 ADS1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
SLD2Delta(8)-fatty-acid desaturase 2; Plays a major role as delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides with or without a hydroxy group at the 4-position. The enzyme produces both the 8E and 8Z isomers (in a 4:1 ratio). This structural modification contributes to the quantitative partitioning of ceramides between the two major sphingolipid classes, glucosylceramides and glycosylinositolphosphoryl ceramides. Sphingolipids are important membrane components involved in environmental stress responses, such as resista [...] (449 aa)
SLD1Delta(8)-fatty-acid desaturase 1; Plays a major role as delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides with or without a hydroxy group at the 4-position. The enzyme produces both the 8E and 8Z isomers (in a 4:1 ratio). This structural modification contributes to the quantitative partitioning of ceramides between the two major sphingolipid classes, glucosylceramides and glycosylinositolphosphoryl ceramides. Sphingolipids are important membrane components involved in environmental stress responses, such as resista [...] (449 aa)
DES-1-LIKESphingolipid delta(4)-desaturase DES1-like; Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives. May be required for the biosynthesis of glucosylceramides. (332 aa)
ADS2Delta-9 acyl-lipid desaturase 2; Involved in delta-9 desaturation of fatty acids. Belongs to the fatty acid desaturase type 1 family. (307 aa)
ADS3.2Probable lipid desaturase ADS3.2, chloroplastic; Belongs to the fatty acid desaturase type 1 family. (361 aa)
T21E18.14Delta-9 desaturase-like 1 protein; Belongs to the fatty acid desaturase type 1 family. (299 aa)
T21E18.15Delta-9 desaturase-like 2 protein; Belongs to the fatty acid desaturase type 1 family. (299 aa)
ADS4Delta-9 desaturase-like 4 protein; Belongs to the fatty acid desaturase type 1 family. (300 aa)
T2D23.6Delta-9 desaturase-like 5 protein; Belongs to the fatty acid desaturase type 1 family. (299 aa)
T21E18.17Delta-9 desaturase-like 3 protein; Belongs to the fatty acid desaturase type 1 family. (299 aa)
ADS3Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic; Fatty acid desaturase involved in the first desaturation step leading to the formation of hexadeca 7,10,13-trienoic acid (16:3(7Z,10Z,13Z)), the major functional components of thylakoid membranes. Required for chloroplast biogenesis at low temperature. Also indirectly involved in the production of the oxylipin dinor-oxo-phyto- dienoic acid implicated in wound signaling. (371 aa)
FAD3Acyl-lipid omega-3 desaturase (cytochrome b5), endoplasmic reticulum; Microsomal (ER) omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine and, possibly, other phospholipids. (386 aa)
FAD8Temperature-sensitive sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic; Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. (435 aa)
FAD2Delta(12)-fatty-acid desaturase; ER (microsomal) omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. Delta(12)-desaturase with regioselectivity determined by the double bond (delta(9) position) and carboxyl group of the substrate. Can use both 16:1 and 18:1 fatty acids as substrates. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine (PC) and, possibly, other phospholipids. Very low constitutive hydroxylation activity. Required [...] (383 aa)
FAD6Omega-6 fatty acid desaturase, chloroplastic; Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. (448 aa)
FAD7Sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic; Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. (446 aa)
ADS1Delta-9 acyl-lipid desaturase 1; Involved in delta-9 desaturation of fatty acids. Belongs to the fatty acid desaturase type 1 family. (305 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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