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PPC6-6 PPC6-6 K20I9.2 K20I9.2 MDC8.3 MDC8.3 MGD8.13 MGD8.13 MLM24.7 MLM24.7 F1O13.18 F1O13.18 ABI2 ABI2 T29F13.5 T29F13.5 T12M4.15 T12M4.15 PLL2 PLL2 PLL4 PLL4 HAI3 HAI3 F26O13.10 F26O13.10 PPC3-1.2 PPC3-1.2 DBP1 DBP1 F16M2.170 F16M2.170 PPC6-1 PPC6-1 T2E12.9 T2E12.9 F18C1.9 F18C1.9 F21H2.4 F21H2.4 F3O9.3 F3O9.3 F26O13.110 F26O13.110 PLL3 PLL3 F23F1.6 F23F1.6 PPC4-2 PPC4-2 F17I5.110 F17I5.110 PLL1 PLL1 F26P21.70 F26P21.70 KAPP KAPP ABI1 ABI1 PP2CA PP2CA PPH1 PPH1 PP2C27 PP2C27 K14A17.16 K14A17.16 PPC6-7 PPC6-7 T17J13.220 T17J13.220 MYF5.1 MYF5.1 F6A4.150 F6A4.150 F9G14.70 F9G14.70 F20M13.80 F20M13.80 F7A7.220 F7A7.220 T12G13.100 T12G13.100 F11C18.60 F11C18.60 F8M12.14 F8M12.14 PP2C5 PP2C5 F28L1.21 F28L1.21 MPH15.11 MPH15.11 PP2C52 PP2C52 T11I11.14 T11I11.14 MAJ23.3 MAJ23.3 POL POL F10K1.13 F10K1.13 WIN2 WIN2 F20B17.6 F20B17.6 F28H19.16 F28H19.16 F16M2.190 F16M2.190 F20O9.80 F20O9.80 MFH8.8 MFH8.8 PP2C6 PP2C6 HAB1 HAB1 PP2C74 PP2C74 SAG113 SAG113 K2A18.16 K2A18.16 AHG1 AHG1 T3F24.2 T3F24.2 F12A21.5 F12A21.5 K7L4.6 K7L4.6 PP2C38 PP2C38 PAPP2C PAPP2C T1N24.8 T1N24.8 T10F20.4 T10F20.4 F21D18.27 F21D18.27 HAB2 HAB2 AIP1 AIP1 PLL5 PLL5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPC6-6Probable protein phosphatase 2C 1; May act as negative regulator of GCN5. (462 aa)
K20I9.2Probable protein phosphatase 2C 41. (351 aa)
MDC8.3Probable protein phosphatase 2C 40. (493 aa)
MGD8.13Probable protein phosphatase 2C 43. (422 aa)
MLM24.7Putative protein phosphatase 2C-like protein 44; Belongs to the PP2C family. (260 aa)
F1O13.18Protein phosphatase 2C family protein. (193 aa)
ABI2Protein phosphatase 2C 77; Repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), high light stress, response to glucose, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as H(2)O(2) and oxidative burst in response to ABA and dehydration. Represses GHR1 and, to some extent, SRK2E/OST1, kinases involved in the regulation of SLAC1-dependent stomatal closure. Controls [...] (423 aa)
T29F13.5Probable protein phosphatase 2C 28. (339 aa)
T12M4.15Probable protein phosphatase 2C 5. (428 aa)
PLL2Probable protein phosphatase 2C 66. (674 aa)
PLL4Probable protein phosphatase 2C 23; Involved in leaf development regulation. Belongs to the PP2C family. (654 aa)
HAI3Probable protein phosphatase 2C 24. (362 aa)
F26O13.10Probable protein phosphatase 2C 46; Belongs to the PP2C family. (379 aa)
PPC3-1.2Probable protein phosphatase 2C 20; May be involved in defense signaling; Belongs to the PP2C family. (290 aa)
DBP1Probable protein phosphatase 2C 22; Belongs to the PP2C family. (392 aa)
F16M2.170Putative protein phosphatase 2C 50. (423 aa)
PPC6-1Probable protein phosphatase 2C 33. (492 aa)
T2E12.9Probable protein phosphatase 2C 15. (436 aa)
F18C1.9Probable protein phosphatase 2C 34. (358 aa)
F21H2.4Probable protein phosphatase 2C 10. (282 aa)
F3O9.3Probable protein phosphatase 2C 6. (491 aa)
F26O13.110Probable protein phosphatase 2C 47. (361 aa)
PLL3Probable protein phosphatase 2C 36. (650 aa)
F23F1.6Probable protein phosphatase 2C 25; Protein phosphatase that negatively regulates defense respones. Inactivates MPK4 and MPK6 MAP kinases involved in stress and defense signaling; Belongs to the PP2C family. (396 aa)
PPC4-2Probable protein phosphatase 2C 21. (355 aa)
F17I5.110Probable protein phosphatase 2C 63. (380 aa)
PLL1Protein phosphatase 2C 29; Involved in the regulation of pedicel length and of CLAVATA pathways controlling stem cell identity at shoot and flower meristems. Belongs to the PP2C family. (783 aa)
F26P21.70Probable protein phosphatase 2C 61. (326 aa)
KAPPProtein phosphatase 2C 70; Dephosphorylates the Ser/Thr receptor-like kinase RLK5. May function as a signaling component in a pathway involving RLK5. Binds and dephosphorylates CLAVATA1 (CLV1). Functions as a negative regulator of the CLV1 signaling in plant development. Dephosphorylates SERK1 receptor kinase on threonine residues in the A-loop. Dephosphorylation of SERK1 controls SERK1 internalization. Component of a signaling pathway which mediates adaptation to NaCl stress. Is not a component of the SALT OVERLY SENSITIVE (SOS) pathway. (581 aa)
ABI1Protein phosphatase 2C 56; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syrin [...] (434 aa)
PP2CAProtein phosphatase 2C 37; Major negative regulator of abscisic acid (ABA) responses during seed germination and cold acclimation. Confers insensitivity to ABA. Modulates negatively the AKT2/3 activity, which mediates K(+) transport and membrane polarization during stress situations, probably by dephosphorylation. Prevents stomata closure by inactivating the S- type anion efflux channel SLAC1 and its activator SRK2E. Represses KIN10 activity by the specific dephosphorylation of its T-loop Thr-198, leading to a poststress inactivation of SnRK1 signaling. (399 aa)
PPH1Protein phosphatase 2C 57. (388 aa)
PP2C27Probable protein phosphatase 2C 27; Confers salt tolerance by triggering the expression of stress-responsive genes; Belongs to the PP2C family. (380 aa)
K14A17.16Probable protein phosphatase 2C 42; Belongs to the PP2C family. (384 aa)
PPC6-7Probable protein phosphatase 2C 73. (373 aa)
T17J13.220Probable protein phosphatase 2C 49. (384 aa)
MYF5.1Putative protein phosphatase 2C-like protein 45; Belongs to the PP2C family. (245 aa)
F6A4.150Probable protein phosphatase 2C 71. (447 aa)
F9G14.70Probable protein phosphatase 2C 67. (370 aa)
F20M13.80Probable protein phosphatase 2C 64. (400 aa)
F7A7.220Probable protein phosphatase 2C 65; Belongs to the PP2C family. (382 aa)
T12G13.100Putative protein phosphatase 2C 53. (212 aa)
F11C18.60Probable protein phosphatase 2C 60; Belongs to the PP2C family. (357 aa)
F8M12.14Probable protein phosphatase 2C 54; Belongs to the PP2C family. (295 aa)
PP2C5Probable protein phosphatase 2C 30. (390 aa)
F28L1.21Probable protein phosphatase 2C 35. (348 aa)
MPH15.11Probable protein phosphatase 2C 68; Belongs to the PP2C family. (393 aa)
PP2C52Probable protein phosphatase 2C 52. (468 aa)
T11I11.14Probable protein phosphatase 2C 17. (283 aa)
MAJ23.3Probable protein phosphatase 2C 69. (354 aa)
POLProtein phosphatase 2C 32; Involved in the regulation of pedicel length and of CLAVATA pathways controlling stem cell identity at shoot and flower meristems. (856 aa)
F10K1.13Probable protein phosphatase 2C 2. (380 aa)
WIN2Probable protein phosphatase 2C 59; Protein phosphatase that modulates defense response to pathogenic bacteria, conferring resistance and promoting salicylic acid (SA) accumulation; Belongs to the PP2C family. (311 aa)
F20B17.6Probable protein phosphatase 2C 18; Belongs to the PP2C family. (504 aa)
F28H19.16Probable protein phosphatase 2C 11; Belongs to the PP2C family. (371 aa)
F16M2.190Probable protein phosphatase 2C 51. (528 aa)
F20O9.80Probable protein phosphatase 2C 58. (283 aa)
MFH8.8Probable protein phosphatase 2C 76. (420 aa)
PP2C6Probable protein phosphatase 2C 48. (384 aa)
HAB1Protein phosphatase 2C 16; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Confers enhanced sensitivity to drought. Belongs to the PP2C family. (511 aa)
PP2C74Probable protein phosphatase 2C 74; Acts as a protein phosphatase; Belongs to the PP2C family. (448 aa)
SAG113Probable protein phosphatase 2C 78; Acts as negative regulator of abscisic acid (ABA) signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Activated by the NAC029/NAP transcription factor during ABA signaling in senescing leaves. Functions as negative regulator of osmotic stress and ABA signaling. Acts as negative regulator of response to drought. Belongs to the PP2C family. (413 aa)
K2A18.16Probable protein phosphatase 2C 79. (385 aa)
AHG1Probable protein phosphatase 2C 75; Negative regulator of abscisic acid (ABA) responses during seed germination; Belongs to the PP2C family. (416 aa)
T3F24.2Probable protein phosphatase 2C 12. (428 aa)
F12A21.5Probable protein phosphatase 2C 14. (445 aa)
K7L4.6Probable protein phosphatase 2C 39. (289 aa)
PP2C38Probable protein phosphatase 2C 38; Involved in pathogen-associated molecular pattern (PAMP)- triggered immunity (PTI) signaling. Negatively regulates immune responses by controlling the phosphorylation and activation status of BIK1, a central rate-limiting kinase in PTI signaling. Impairs the phosphorylation of the NADPH oxidase RBOHD by BIK1. (385 aa)
PAPP2CProbable protein phosphatase 2C 9; Involved in the regulation of phytochrome signaling. May regulate phytochrome-interacting factor 3 (PIF3) through the dephosphorylation of phytochrome; Belongs to the PP2C family. (281 aa)
T1N24.8Probable protein phosphatase 2C 72. (331 aa)
T10F20.4Probable protein phosphatase 2C 8. (351 aa)
F21D18.27Probable protein phosphatase 2C 13. (383 aa)
HAB2Protein phosphatase 2C 7; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. (511 aa)
AIP1Protein phosphatase 2C 3; Involved in the negative regulation of the K(+) potassium channel AKT1 by its dephosphorylation, antagonistically to CIPK proteins (e.g. CIPK23). Functions as positive regulator of abscisic acid-mediated cell signaling during seedling growth. Involved in the regulation of seed dormancy. Acts as negative regulator of seed dormancy by inhibiting abscisic signaling and subsequently activating gibberellic acid signaling ; Belongs to the PP2C family. (442 aa)
PLL5Probable protein phosphatase 2C 4; Involved in leaf development regulation. Belongs to the PP2C family. (662 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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