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KAS_III KAS_III KAS1 KAS1 HMGS HMGS FAE1 FAE1 KCS8 KCS8 PED1 PED1 FDH FDH KAT5 KAT5 KCS2 KCS2 KAS KAS PKSB PKSB KAT1-2 KAT1-2 AAT1 AAT1 KCS5 KCS5 KCS7 KCS7 KAS2 KAS2 KCS20 KCS20 KCS21 KCS21 AACT1 AACT1 KCS4 KCS4 KCS3 KCS3 KCS19 KCS19 KCS1 KCS1 KCS12 KCS12 KCS9 KCS9 KCS14 KCS14 KCS15 KCS15 KCS16 KCS16 CUT1 CUT1 HIC HIC KCS11 KCS11 KCS17 KCS17 F6N15.12 F6N15.12 CHS CHS PKSA PKSA
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KAS_III3-oxoacyl-[acyl-carrier-protein] synthase III, chloroplastic; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. KAS III catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities (By similarity); Belongs to the thiolase-like superfamily. FabH family. (404 aa)
KAS13-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity). (473 aa)
HMGSHydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Devoided of acetoacetyl-CoA thiolase (AACT) activity. Required for the development of both tapetosomes and elaioplasts in tapetal cells and for pollen viability during pollen tube elongation; Belongs to the thiolase-like superfamily. HMG-CoA synthase family. (461 aa)
FAE13-ketoacyl-CoA synthase 18; Contributes to fatty acids elongation and stockage in developing seeds. Active on both saturated and mono-unsaturated acyl- CoAs of 16 and 18 carbons. Required for the elongation of C18 to C20 and of C20 to C22 fatty acids. Mediates also the synthesis of VLCFAs from 20 to 26 carbons in length (e.g. C20:1, C20, C22:1, C22, C24:1, C24, C26) (Ref.4, Ref.5,. Has no activity with polyunsaturated C18:2 and C18:3 or with acyl-CoAs having 22 carbons or longer chain length. (506 aa)
KCS83-ketoacyl-CoA synthase 8. (481 aa)
PED13-ketoacyl-CoA thiolase 2, peroxisomal; Involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Confers sensitivity to 2,4-dichlorophenoxybutiric acid (2,4-DB). Required for local and systemic induction of jasmonic acid (JA) biosynthesis after wounding. Seems to be involved in JA biosynthesis during senescence. (462 aa)
FDH3-ketoacyl-CoA synthase 10; Contributes to cuticular wax and suberin biosynthesis. Prevents the postgenital fusion of epiderm cells in organs in contact, as well as ectopic pollen hydration and germination. Required during ovules formation. May regulate an epidermis-specific developmental program during gynoecial ontogeny. (550 aa)
KAT53-ketoacyl-CoA thiolase 5, peroxisomal; Probably involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Involved in systemic jasmonic acid (JA) biosynthesis after wounding and may be during senescence. (457 aa)
KCS23-ketoacyl-CoA synthase 2; Mediates the synthesis of VLCFAs from 22 to 26 carbons in length (e.g. C22, C24, C26). Involved in the elongation of C20 fatty acid suberin precursors. Functionally redundant with KCS20 in the two-carbon elongation of C22 fatty acids that is required for cuticular wax and root suberin biosynthesis ; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (528 aa)
KAS3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; Catalyzes all the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Able to elongate saturated acyl chains from 4 to at least 16 carbons. Uses malonyl-CoA but not acetyl-CoA as primer substrate. When expressed in a heterologous system, reveals a bimodal distribution of products, with peaks at C8 and C14-C16. The major product of the reaction (octanoyl-ACP) is required for the lipoylation of essential mitochondrial proteins. (461 aa)
PKSBType III polyketide synthase B; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors. Favorite substrates for are midchain- and v- hydroxylated fatty acyl-CoAs (e.g. 12-hydroxyoctadecanoyl-CoA and 16- [...] (392 aa)
KAT1-23-ketoacyl-CoA thiolase 1, peroxisomal; Involved in fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Implicated in jasmonic acid (JA) biosynthesis (By similarity). Belongs to the thiolase-like superfamily. Thiolase family. (443 aa)
AAT1Acetyl-CoA acetyltransferase, cytosolic 1. (403 aa)
KCS53-ketoacyl-CoA synthase 5; Mediates mostly the synthesis of VLCFAs from 26 to 30 carbons in length (e.g. C20:1, C26, C28, C30). (492 aa)
KCS73-ketoacyl-CoA synthase 7. (460 aa)
KAS23-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic; Essential protein that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-16 and C-16 to unsaturated C-18 fatty acids. Confers resistance to low temperatures by maintaining chloroplast membranes integrity. Involved in the regulation of fatty acids ratios during seed metabolism. Required for embryo development, especially at the transition from the globular to the heart stage. (541 aa)
KCS203-ketoacyl-CoA synthase 20; Mediates the synthesis of VLCFAs from 22 to 26 carbons in length (e.g. C22, C24, C26). Functionally redundant with KCS2 in the two-carbon elongation of C22 fatty acids that is required for cuticular wax and root suberin biosynthesis ; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (529 aa)
KCS21Probable 3-ketoacyl-CoA synthase 21; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (464 aa)
AACT1Probable acetyl-CoA acetyltransferase, cytosolic 2; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
KCS43-ketoacyl-CoA synthase 4. (516 aa)
KCS33-ketoacyl-CoA synthase 3. (478 aa)
KCS193-ketoacyl-CoA synthase 19. (464 aa)
KCS13-ketoacyl-CoA synthase 1; Contributes to cuticular wax and suberin biosynthesis. Involved in both decarbonylation and acyl-reduction wax synthesis pathways. Elongase condensing enzyme mostly active with saturated fatty acids, especially with 16:0, 16:1, 18:0, and 20:0. Mediates the synthesis of VLCFAs from 20 to 26 carbons in length (e.g. C20:1, C20, C22, C24 and C26); Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (528 aa)
KCS123-ketoacyl-CoA synthase 12. (476 aa)
KCS93-ketoacyl-CoA synthase 9; Involved in the elongation of C22 to C24 fatty acids, which are precursors for the biosynthesis of cuticular waxes, aliphatic suberins, and membrane lipids, including sphingolipids and phospholipids. (512 aa)
KCS14Probable 3-ketoacyl-CoA synthase 14. (459 aa)
KCS153-ketoacyl-CoA synthase 15. (451 aa)
KCS163-ketoacyl-CoA synthase 16. (493 aa)
CUT13-ketoacyl-CoA synthase 6; Contributes to cuticular wax and suberin biosynthesis. Involved in both decarbonylation and acyl-reduction wax synthesis pathways. Required for elongation of C24 fatty acids, an essential step of the cuticular wax production. Major condensing enzyme for stem wax and pollen coat lipid biosynthesis. (497 aa)
HIC3-ketoacyl-CoA synthase 13; Contributes to cuticular wax and suberin biosynthesis (By similarity). Regulates negatively the stomatal development in elevated CO(2) conditions; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (466 aa)
KCS113-ketoacyl-CoA synthase 11; Active on both saturated and mono-unsaturated acyl chains C16 to C20; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (509 aa)
KCS173-ketoacyl-CoA synthase 17; Active on saturated acyl-CoAs up to C22. Mediates the synthesis of VLCFAs from 20 to 26 carbons in length (e.g. C20:1, C20, C24, C26). (487 aa)
F6N15.12Type III polyketide synthase C; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (385 aa)
CHSChalcone synthase; The primary product of this enzyme is 4,2',4',6'- tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. (395 aa)
PKSAType III polyketide synthase A; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors. Favorite substrates for are midchain- and v- hydroxylated fatty acyl-CoAs (e.g. 12-hydroxyoctadecanoyl-CoA and 16- [...] (395 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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