(13 nodes) Isopropylmalate dehydrogenase-like domain network (Arabidopsis thaliana)

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	IDH2	Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (367 aa)
	A0A1P8AT86	Isocitrate/isopropylmalate dehydrogenase family protein. (195 aa)
	IDH3	Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (368 aa)
	IMDH2	3-isopropylmalate dehydrogenase 2, chloroplastic; Involved in leucine biosynthesis; catalyzes the oxidative decarboxylation step in leucine biosynthesis (primary metabolism). Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate, 3-IPM) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Required during pollen development and involved in embryo sac development. (405 aa)
	IDH1	Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (367 aa)
	IDH6	Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (374 aa)
	T15N1.80	Isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (485 aa)
	IDH5	Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (374 aa)
	IMDH1	3-isopropylmalate dehydrogenase 1, chloroplastic; Involved in both glucosinolate and leucine biosynthesis; catalyzes the oxidative decarboxylation step in both leucine biosynthesis (primary metabolism) and methionine chain elongation of glucosinolates (specialized metabolism). Catalyzes the oxidation of 3- carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate, 3-IPM) to 3- carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4- methyl-2 oxopentanoate. Required during pollen development and involved in embryo sac development. More active on 3-isopropylmalate and NAD(+) than [...] (409 aa)
	IDH4	Putative isocitrate dehydrogenase [NAD] subunit-like 4; Performs an essential role in the oxidative function of the citric acid cycle. (294 aa)
	IMDH3	3-isopropylmalate dehydrogenase 3, chloroplastic; Involved in leucine biosynthesis; catalyzes the oxidative decarboxylation step in leucine biosynthesis (primary metabolism). Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate, 3-IPM) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (404 aa)
	ICDH	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (416 aa)
	CICDH	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (410 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1P8AT86	CICDH	A0A1P8AT86	Q9SRZ6	Isocitrate/isopropylmalate dehydrogenase family protein.	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.461
A0A1P8AT86	ICDH	A0A1P8AT86	Q9SLK0	Isocitrate/isopropylmalate dehydrogenase family protein.	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.461
A0A1P8AT86	T15N1.80	A0A1P8AT86	Q8LPJ5	Isocitrate/isopropylmalate dehydrogenase family protein.	Isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.461
CICDH	A0A1P8AT86	Q9SRZ6	A0A1P8AT86	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate/isopropylmalate dehydrogenase family protein.	0.461
CICDH	ICDH	Q9SRZ6	Q9SLK0	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.901
CICDH	IDH1	Q9SRZ6	Q8LFC0	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.988
CICDH	IDH2	Q9SRZ6	P93032	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.986
CICDH	IDH3	Q9SRZ6	O81796	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.988
CICDH	IDH4	Q9SRZ6	Q9LQK9	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Putative isocitrate dehydrogenase [NAD] subunit-like 4; Performs an essential role in the oxidative function of the citric acid cycle.	0.986
CICDH	IDH5	Q9SRZ6	Q945K7	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.974
CICDH	IDH6	Q9SRZ6	Q8LG77	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.990
CICDH	IMDH1	Q9SRZ6	Q9FMT1	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	3-isopropylmalate dehydrogenase 1, chloroplastic; Involved in both glucosinolate and leucine biosynthesis; catalyzes the oxidative decarboxylation step in both leucine biosynthesis (primary metabolism) and methionine chain elongation of glucosinolates (specialized metabolism). Catalyzes the oxidation of 3- carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate, 3-IPM) to 3- carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4- methyl-2 oxopentanoate. Required during pollen development and involved in embryo sac development. More active on 3-isopropylmalate and NAD(+) than [...]	0.461
CICDH	IMDH2	Q9SRZ6	P93832	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	3-isopropylmalate dehydrogenase 2, chloroplastic; Involved in leucine biosynthesis; catalyzes the oxidative decarboxylation step in leucine biosynthesis (primary metabolism). Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate, 3-IPM) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Required during pollen development and involved in embryo sac development.	0.547
CICDH	IMDH3	Q9SRZ6	Q9SA14	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	3-isopropylmalate dehydrogenase 3, chloroplastic; Involved in leucine biosynthesis; catalyzes the oxidative decarboxylation step in leucine biosynthesis (primary metabolism). Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate, 3-IPM) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.513
CICDH	T15N1.80	Q9SRZ6	Q8LPJ5	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.901
ICDH	A0A1P8AT86	Q9SLK0	A0A1P8AT86	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate/isopropylmalate dehydrogenase family protein.	0.461
ICDH	CICDH	Q9SLK0	Q9SRZ6	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Cytosolic isocitrate dehydrogenase [NADP]; May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway. May be involved in the production of NADPH to promote redox signaling or homeostasis in response to oxidative stress. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.901
ICDH	IDH1	Q9SLK0	Q8LFC0	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.989
ICDH	IDH2	Q9SLK0	P93032	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.989
ICDH	IDH3	Q9SLK0	O81796	Peroxisomal isocitrate dehydrogenase [NADP]; May be involved in response to oxidative stresses. Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.990