(22 nodes) High mobility group box domain superfamily network (Arabidopsis thaliana)

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Your Input:
	YAB4	Axial regulator YABBY 4; Essential for the formation and the abaxial-adaxial asymmetric growth of the ovule outer integument. Belongs to the YABBY family. (231 aa)
	HMGB11	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content. (337 aa)
	HMGB10	High mobility group B protein 10; Binds preferentially DNA with A/T-rich content. (319 aa)
	HMGB15	High mobility group B protein 15; Binds preferentially DNA with A/T-rich content. Belongs to the HMGB family. (448 aa)
	HMGB9	High mobility group B protein 9; Binds preferentially DNA with A/T-rich content. Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus. (338 aa)
	HMGB6	High mobility group B protein 6. (456 aa)
	HMGB13	High mobility group B protein 13. (446 aa)
	YAB2	Putative axial regulator YABBY 2; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. (184 aa)
	YAB3	Axial regulator YABBY 3; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development. Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems. Binds DNA without sequence specificity. Belongs to the YABBY family. (240 aa)
	HMGB7	High mobility group B protein 7; Binds preferentially double-stranded supercoiled DNA. Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus ; Belongs to the HMGB family. (241 aa)
	HMGB2	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses. (144 aa)
	HMGB1	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family. (178 aa)
	YAB1	Axial regulator YABBY 1; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development (Ref.3, Ref.6,. Required during flower formation and development, particularly for the patterning of floral organs. Positive regulator of class B (AP3 and PI) activity in whorls 2 and 3. Negative regulator of class B activity in whorl 1 and of SUP activity in whorl 3. Interacts with class A proteins (AP1, AP2 and LUG) to repress class C (AG) activity in whorls 1 and 2. Contributes to the repression [...] (229 aa)
	HMGB5	High mobility group B protein 5; Binds preferentially double-stranded DNA. Confers resistance to salt and drought stresses. (125 aa)
	HMGB12	High mobility group B protein 12; Belongs to the HMGB family. (149 aa)
	HMGB14	High mobility group B protein 14; Belongs to the HMGB family. (151 aa)
	HMGB3	High mobility group B protein 3; Binds preferentially double-stranded DNA. (141 aa)
	SSRP1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (646 aa)
	HMGB4	High mobility group B protein 4; Binds preferentially double-stranded DNA. (138 aa)
	K18I23.13	HMG-box (High mobility group) DNA-binding family protein. (220 aa)
	YAB5	Axial regulator YABBY 5; Promotes adaxial cell identity. Regulates the initiation of embryonic shoot apical meristem (SAM) development. Belongs to the YABBY family. (164 aa)
	CRC	Protein CRABS CLAW; Transcription factor required for the initiation of nectary development. Also involved in suppressing early radial growth of the gynoecium, in promoting its later elongation and in fusion of its carpels by regulating both cell division and expansion. Establishes the polar differentiation in the carpels by specifying abaxial cell fate in the ovary wall. Regulates both cell division and expansion. Belongs to the YABBY family. (181 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HMGB1	HMGB11	O49595	Q9LG02	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	0.814
HMGB1	HMGB12	O49595	Q941D1	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	High mobility group B protein 12; Belongs to the HMGB family.	0.903
HMGB1	SSRP1	O49595	Q05153	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.637
HMGB10	HMGB11	Q9LTT3	Q9LG02	High mobility group B protein 10; Binds preferentially DNA with A/T-rich content.	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	0.706
HMGB10	HMGB15	Q9LTT3	Q9MAT6	High mobility group B protein 10; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 15; Binds preferentially DNA with A/T-rich content. Belongs to the HMGB family.	0.693
HMGB10	HMGB9	Q9LTT3	Q9SGS2	High mobility group B protein 10; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 9; Binds preferentially DNA with A/T-rich content. Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus.	0.704
HMGB10	SSRP1	Q9LTT3	Q05153	High mobility group B protein 10; Binds preferentially DNA with A/T-rich content.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.573
HMGB11	HMGB1	Q9LG02	O49595	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	0.814
HMGB11	HMGB10	Q9LG02	Q9LTT3	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 10; Binds preferentially DNA with A/T-rich content.	0.706
HMGB11	HMGB15	Q9LG02	Q9MAT6	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 15; Binds preferentially DNA with A/T-rich content. Belongs to the HMGB family.	0.667
HMGB11	HMGB2	Q9LG02	O49596	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses.	0.824
HMGB11	HMGB9	Q9LG02	Q9SGS2	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	High mobility group B protein 9; Binds preferentially DNA with A/T-rich content. Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus.	0.732
HMGB11	SSRP1	Q9LG02	Q05153	Putative high mobility group B protein 11; Binds preferentially DNA with A/T-rich content.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.573
HMGB12	HMGB1	Q941D1	O49595	High mobility group B protein 12; Belongs to the HMGB family.	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	0.903
HMGB12	HMGB14	Q941D1	O64702	High mobility group B protein 12; Belongs to the HMGB family.	High mobility group B protein 14; Belongs to the HMGB family.	0.932
HMGB12	HMGB2	Q941D1	O49596	High mobility group B protein 12; Belongs to the HMGB family.	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses.	0.801
HMGB12	HMGB5	Q941D1	O49597	High mobility group B protein 12; Belongs to the HMGB family.	High mobility group B protein 5; Binds preferentially double-stranded DNA. Confers resistance to salt and drought stresses.	0.886
HMGB12	HMGB6	Q941D1	Q9SUP7	High mobility group B protein 12; Belongs to the HMGB family.	High mobility group B protein 6.	0.758
HMGB12	SSRP1	Q941D1	Q05153	High mobility group B protein 12; Belongs to the HMGB family.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.657
HMGB13	HMGB14	Q9T012	O64702	High mobility group B protein 13.	High mobility group B protein 14; Belongs to the HMGB family.	0.758