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GCP2 GCP2 GCP1 GCP1 F17I23.350 F17I23.350 HSP70-17 HSP70-17 F4HZF4_ARATH F4HZF4_ARATH HSP70-15 HSP70-15 A0A1P8ARU2 A0A1P8ARU2 BIP3 BIP3 T24P15.8 T24P15.8 HSP70-9 HSP70-9 ARP4 ARP4 ATHXK4 ATHXK4 HXK1 HXK1 BIP2 BIP2 HXK2 HXK2 ACT9 ACT9 ACT2 ACT2 ACT8 ACT8 HSP70-18 HSP70-18 ARP4A ARP4A ARP8 ARP8 HXK3 HXK3 HSP70-10 HSP70-10 HSP70-4 HSP70-4 BIP1 BIP1 HKL1 HKL1 ARP2-2 ARP2-2 ARP9 ARP9 HSP70-7 HSP70-7 GLPK GLPK HSP70-14 HSP70-14 HSP70-5 HSP70-5 HSP70-16 HSP70-16 ARP3 ARP3 HSP70-8 HSP70-8 HSP70-6 HSP70-6 HKL3 HKL3 XK2 XK2 ARP5 ARP5 ACT5 ACT5 ARP6 ARP6 F26G16.16 F26G16.16 XK1 XK1 PANK2 PANK2 ARP7 ARP7 ACT12 ACT12 ACT11 ACT11 ACT4 ACT4 ACT7 ACT7 HSP70-2 HSP70-2 HSP70-1 HSP70-1 ACT3 ACT3 ACT1 ACT1 PANK1 PANK1 HSP70-3 HSP70-3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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GCP2Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (353 aa)
GCP1Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance (By similarity). May have a role in embryonic development in plants. Belongs to the KAE1 / TsaD family. (480 aa)
F17I23.350FGGY family of carbohydrate kinase. (579 aa)
HSP70-17Heat shock 70 kDa protein 17. (867 aa)
F4HZF4_ARATHPpx-GppA phosphatase. (545 aa)
HSP70-15Heat shock 70 kDa protein 15; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. Belongs to the heat shock protein 70 (TC 1.A.33) family. HSP110/SSE subfamily. (831 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
BIP3Heat shock 70 kDa protein BIP3; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Required for pollen development and pollen tube growth. May be required for the early stages of female gametophyte development, but not for polar nuclei fusion during female gametophyte. Possesses ATPase activity in vitro. Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK sub [...] (675 aa)
T24P15.8Actin family protein; Belongs to the actin family. (329 aa)
HSP70-9Heat shock 70 kDa protein 9, mitochondrial; Chaperone involved in the maturation of iron-sulfur [Fe-S] cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HSCB and ISU1. In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). (682 aa)
ARP4Actin-related protein 4; Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure. (441 aa)
ATHXK4Hexokinase-4; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (502 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
BIP2Heat shock 70 kDa protein BIP2; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Req [...] (668 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
ACT9Putative actin-9; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth; Belongs to the actin family. (366 aa)
ACT2Actin-2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
ACT8Actin-8; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
HSP70-18Heat shock 70 kDa protein 18; Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (617 aa)
ARP4AActin-related protein 4A. (145 aa)
ARP8Actin-related protein 8. (471 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
HSP70-10Heat shock 70 kDa protein 10, mitochondrial; Chaperone involved in the maturation of iron-sulfur [Fe-S] cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HSCB and ISU1 (By similarity). In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (682 aa)
HSP70-4Heat shock 70 kDa protein 4; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). ATP-dependent molecular chaperone that assists folding of unfolded or misfolded proteins under stress conditions. Mediates plastid precursor degradation to prevent cytosolic precursor accumulation, together with the E3 ubiquitin-protein ligase CHIP. Recognizes specific sequence motifs in tr [...] (650 aa)
BIP1Heat shock 70 kDa protein BIP1; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Req [...] (669 aa)
HKL1Hexokinase-3; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (498 aa)
ARP2-2Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, [...] (389 aa)
ARP9Actin-related protein 9. (596 aa)
HSP70-7Heat shock 70 kDa protein 7, chloroplastic; Acts redundantly with HSP70-6 in the thermotolerance of germinating seeds. Plays an important role in the protein precursor import into chloroplasts; Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (718 aa)
GLPKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Required for resistance to nonhost Pseudomonas bacteria and to the pathogenic fungus B.cinerea. (522 aa)
HSP70-14Heat shock 70 kDa protein 14; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (831 aa)
HSP70-5Heat shock 70 kDa protein 5; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (646 aa)
HSP70-16Heat shock 70 kDa protein 16; Belongs to the heat shock protein 70 (TC 1.A.33) family. HSP110/SSE subfamily. (763 aa)
ARP3Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, [...] (427 aa)
HSP70-8Heat shock 70 kDa protein 8; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (563 aa)
HSP70-6Heat shock 70 kDa protein 6, chloroplastic; Acts redundantly with HSP70-7 in the thermotolerance of germinating seeds. Plays an important role in the protein precursor import into chloroplasts. (718 aa)
HKL3Probable hexokinase-like 2 protein; Fructose and glucose phosphorylating enzyme. (493 aa)
XK2Xylulose kinase 2; Mediates 1-deoxy-D-xylulose (DX) phosphorylation in the cytoplasm prior to the translocation of 1-deoxy-D-xylulose 5-phosphate into plastids. Can also phosphorylates D-xylulose (Xyl). Uses preferentially ATP as cosubstrate; Belongs to the FGGY kinase family. (558 aa)
ARP5Actin-related protein 5; Probable subunit of a chromatin-remodeling complex. Involved in DNA repair. Required for multicellular development of all organs. (724 aa)
ACT5Putative actin-5; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth; Belongs to the actin family. (378 aa)
ARP6Actin-related protein 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Binds to the promoter region of FLC chromatin. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. [...] (421 aa)
F26G16.16Actin-like ATPase superfamily protein. (351 aa)
XK1D-ribulose kinase; Exhibits ATP hydrolysis without substrate. Can phosphorylate D-ribulose with low efficiency. (478 aa)
PANK24'-phosphopantetheine phosphatase; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration. Functionally redudant with PANK1. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'-phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre- empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfona [...] (901 aa)
ARP7Actin-related protein 7; Essential protein required during embryogenesis and all plant development stages, probably through a chromatin-mediated regulation of gene expression; Belongs to the actin family. Plant ARP7 subfamily. (363 aa)
ACT12Actin-12; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ACT11Actin-11; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ACT4Actin-4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ACT7Actin-7; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins which is involved in the regulation of hormone-induced plant cell proliferation and callus formation. (377 aa)
HSP70-2Heat shock 70 kDa protein 2; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (653 aa)
HSP70-1Heat shock 70 kDa protein 1; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Probably involved in defense response. Chaperone involved in protein targeting to chloroplasts. May cooperate with SGT1 and HSP90 in R gene-mediated resistance towards the oomycete Hyaloperonospora parasitica (downy mildew). Plays a role with WPP-domain proteins in facilitating WIT1 nuclear [...] (651 aa)
ACT3Actin-3; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ACT1Actin-1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
PANK1Pantothenate kinase 1; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration. Functionally redudant with PANK2. Belongs to the type II pantothenate kinase family. (383 aa)
HSP70-3Heat shock 70 kDa protein 3; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (649 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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