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MYB12 MYB12 PKSA PKSA ANS ANS F6N15.12 F6N15.12 CHS CHS CHI1 CHI1 DFRA DFRA PKSB PKSB CHI3 CHI3 UGT73B2 UGT73B2 LDOX LDOX DTX35 DTX35 FLS1 FLS1 MOP10.14 MOP10.14 TT2 TT2 CHI2 CHI2 TT8 TT8 A3G2XYLT A3G2XYLT JRG21 JRG21 DTX41 DTX41 F3H F3H CYP75B1 CYP75B1 BAN BAN F11B9.11 F11B9.11
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MYB12Transcription factor MYB12; Flavonol-specific transcription activator involved in the regulation of several genes of flavonoid biosynthesis. Activates the expression of CHS, CHI, F3H and FLS1. Controls flavonol biosynthesis mainly in the root. Confers tolerance to UV-B. (371 aa)
PKSAType III polyketide synthase A; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors. Favorite substrates for are midchain- and v- hydroxylated fatty acyl-CoAs (e.g. 12-hydroxyoctadecanoyl-CoA and 16- [...] (395 aa)
ANSProbable 2-oxoglutarate-dependent dioxygenase ANS; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins. (353 aa)
F6N15.12Type III polyketide synthase C; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (385 aa)
CHSChalcone synthase; The primary product of this enzyme is 4,2',4',6'- tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. (395 aa)
CHI1Chalcone--flavonone isomerase 1; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin. (246 aa)
DFRADihydroflavonol 4-reductase; Bifunctional enzyme involved in flavonoid metabolism. (382 aa)
PKSBType III polyketide synthase B; Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors. Favorite substrates for are midchain- and v- hydroxylated fatty acyl-CoAs (e.g. 12-hydroxyoctadecanoyl-CoA and 16- [...] (392 aa)
CHI3Probable chalcone--flavonone isomerase 3; Involved in anthocyanin biosynthesis. Belongs to the chalcone isomerase family. (209 aa)
UGT73B2UDP-glucosyl transferase 73B2; Catalyzes the glycosylation of flavonoids from UDP-glucose. Uses a wide range of flavonoid substrates including flavonols (quercetin, kaempferol, isorhamnetin, 3-OH 7,2',4'-MeO-flavone), flavones (luteolin, apigenin), flavanones (naringenin, hesperetin), flavanonols (taxifolin), isoflavones (genistein, daidzein), flavonol glycosides (quercitrin, isoquercitrin, rutin), and chalcones (isoliquiritigenin). Specific for the C-7 position, with a 20-fold lower activity for the C-3 position; Belongs to the UDP-glycosyltransferase family. (483 aa)
LDOXLeucoanthocyanidin dioxygenase; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins. Possesses low flavonol synthase activity in vitro towards dihydrokaempferol and dihydroquercetin producing kaempferol and quercitin, respectively. Belongs to the iron/ascorbate-dependent oxidoreductase family. (356 aa)
DTX35Protein DETOXIFICATION 35; Multidrug and toxin efflux transporter involved in flavonoid metabolism. Required for proper reproductive development. (488 aa)
FLS1Flavonol synthase/flavanone 3-hydroxylase; Catalyzes the formation of flavonols from dihydroflavonols. It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin. In vitro catalyzes the oxidation of both enantiomers of naringenin to give both cis- and trans-dihydrokaempferol. Belongs to the iron/ascorbate-dependent oxidoreductase family. (336 aa)
MOP10.14Probable 2-oxoglutarate-dependent dioxygenase At5g05600; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins (By similarity). May be involved in the catabolism of cytotoxic polycyclic aromatic hydrocarbons (PAHs). Belongs to the iron/ascorbate-dependent oxidoreductase family. (371 aa)
TT2Transcription factor TT2; Transcription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS). (258 aa)
CHI2Chalcone--flavonone isomerase 2; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity). (223 aa)
TT8Transcription factor TT8; Transcription activator, when associated with MYB75/PAP1 or MYB90/PAP2. Involved in the control of flavonoid pigmentation. Plays a key role in regulating leucoanthocyanidin reductase (BANYULS) and dihydroflavonol-4-reductase (DFR). Not required for leucoanthocyanidin dioxygenase (LDOX) expression. (518 aa)
A3G2XYLTAnthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase; Contributes to the last few anthocyanin biosynthetic steps. Converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1->2)glucoside. Can use 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose as substrates. (468 aa)
JRG21Probable 2-oxoglutarate-dependent dioxygenase JRG21; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins. (363 aa)
DTX41Protein DETOXIFICATION 41; Acts as a flavonoid/H(+)-antiporter that control the vacuolar sequestration of flavonoids in the seed coat endothelium. Could transport the anthocyanin cyanidin-3-O-glucoside and epicatechin 3'-O-glucoside in vitro. (507 aa)
F3HNaringenin,2-oxoglutarate 3-dioxygenase; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. (358 aa)
CYP75B1Flavonoid 3'-monooxygenase; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Convert naringenin to eriodictyol and dihydrokaempferol to dihydroquercetin; Belongs to the cytochrome P450 family. (513 aa)
BANAnthocyanidin reductase; Involved in the biosynthesis of condensed tannins. Converts cyanidin into (-)-epicatechin as the major product. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. (340 aa)
F11B9.11Probable 2-oxoglutarate-dependent dioxygenase At3g111800; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins. Belongs to the iron/ascorbate-dependent oxidoreductase family. (400 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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