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PURA PURA ASE3 ASE3 F28J12.100 F28J12.100 F15C21.8 F15C21.8 PUR5 PUR5 PUR3 PUR3 PUR2 PUR2 IMPDH IMPDH PUR7 PUR7 ASE2 ASE2 ASE1 ASE1 F3O9.15 F3O9.15 PUR4 PUR4 F24D7.15 F24D7.15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PURAAdenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (490 aa)
ASE3Amidophosphoribosyltransferase 3, chloroplastic; Catalyzes the first committed step of 'de novo' purine biosynthesis from glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (532 aa)
F28J12.100Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (536 aa)
F15C21.8Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (527 aa)
PUR5Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic. (389 aa)
PUR3Phosphoribosylglycinamide formyltransferase, chloroplastic. (292 aa)
PUR2Phosphoribosylamine--glycine ligase, chloroplastic. (532 aa)
IMPDHInosine-5'-monophosphate dehydrogenase 1; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (503 aa)
PUR7Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic. (411 aa)
ASE2Amidophosphoribosyltransferase 2, chloroplastic; Catalyzes the first committed step of 'de novo purine biosynthesis from glutamine. Required for chloroplast biogenesis and cell division. Confers sensitivity to the phenyltriazole acetic acid compound [5-(4-chlorophenyl)-1-isopropyl-1H-[1,2,4]triazol-3-yl]-acetic acid (DAS734), a bleaching herbicide; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (561 aa)
ASE1Amidophosphoribosyltransferase 1, chloroplastic; Catalyzes the first committed step of 'de novo' purine biosynthesis from glutamine. Involved in plastid biogenesis and cell division. (566 aa)
F3O9.15Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (502 aa)
PUR4Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial; Essential to the male gametophyte development. Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1407 aa)
F24D7.15GMP synthase (Glutamine-hydrolyzing), putative / glutamine amidotransferase. (534 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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