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PAB1 PAB1 DCP5-L DCP5-L APUM16 APUM16 PNM1 PNM1 APUM13 APUM13 EXA1 EXA1 PAB8 PAB8 APUM11 APUM11 CRS1 CRS1 APUM5 APUM5 APUM25 APUM25 APUM8 APUM8 APUM22 APUM22 APUM10 APUM10 PYM-2 PYM-2 APUM24 APUM24 APUM19 APUM19 MPC MPC APUM12 APUM12 APUM18 APUM18 GCN2 GCN2 APUM21 APUM21 RH12 RH12 AGO3 AGO3 AGO2 AGO2 AGO5 AGO5 APUM4 APUM4 MRF4 MRF4 AGO10 AGO10 APUM20 APUM20 PAB7 PAB7 AGO4 AGO4 APUM3 APUM3 APUM2 APUM2 APUM1 APUM1 MRF3 MRF3 RH8 RH8 CRP1 CRP1 AGO9 AGO9 EIF4G EIF4G APUM14 APUM14 AGO8 AGO8 APUM9 APUM9 PAB5 PAB5 PAB2 PAB2 F20D21.11 F20D21.11 APUM15 APUM15 SPH17 SPH17 EIF(ISO)4G2 EIF(ISO)4G2 MRF2 MRF2 PAB3 PAB3 AGO6 AGO6 MAGO MAGO EIF4E1 EIF4E1 PAB4 PAB4 EIF(ISO)4E EIF(ISO)4E AGO1 AGO1 PAB6 PAB6 Y14 Y14 APUM23 APUM23 EIF(ISO)4G1 EIF(ISO)4G1 EIF4A3 EIF4A3 APUM26 APUM26 MLN51 MLN51 MRF1 MRF1 EIF2A EIF2A T18K17.15 T18K17.15 APUM7 APUM7 APUM17 APUM17 EIF4E3 EIF4E3 EIF4E2 EIF4E2 AGO7 AGO7 RH6 RH6 F20D21.53 F20D21.53 DCP5 DCP5 TIF3E1 TIF3E1 TIF3H1 TIF3H1 APUM6 APUM6
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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PAB1Polyadenylate-binding protein 1; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity); Belongs to the polyadenylate-binding protein type-1 family. (497 aa)
DCP5-LDecapping 5-like protein; As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor (By similarity). (571 aa)
APUM16Putative pumilio homolog 16; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (332 aa)
PNM1Pentatricopeptide repeat-containing protein PNM1, mitochondrial; RNA-binding protein that functions in both mitochondrion and nucleus. In mitochondrion, it is associated with polysomes and may play a role in translation. Required during embryogenesis. In nucleus, might be involved in the regulation of its own gene expression. Belongs to the PPR family. P subfamily. (521 aa)
APUM13Putative pumilio homolog 13; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (527 aa)
EXA1Protein ESSENTIAL FOR POTEXVIRUS ACCUMULATION 1; Translational repressor involved in the negative regulation of immune receptor accumulation via the inhibition of nucleotide- binding leucine-rich repeat (NLR) receptor mediated defense. Represses NLR protein accumulation (e.g. SNC1, RPS4, RPM1 and RPS2). Together with SMG7, helps to restrict effector-triggered immunity (ETI) cell death induction during pathogen infection in a salicylic acid- (SA) and reactive oxygen species- (ROS) independent manner. Required for pathogen-associated molecular pattern (PAMP)-induced suppression of necrot [...] (1714 aa)
PAB8Polyadenylate-binding protein 8; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity). During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp) (By similarity). (671 aa)
APUM11Pumilio homolog 11; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (556 aa)
CRS1Chloroplastic group IIA intron splicing facilitator CRS1, chloroplastic; Required for the splicing of group IIA introns in chloroplasts, by regulating the intron folding. Forms splicing particles with RNA. May also be involved in chloroplast protein translation. (720 aa)
APUM5Pumilio homolog 5; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. (961 aa)
APUM25Putative pumilio homolog 25; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (137 aa)
APUM8Putative pumilio homolog 8, chloroplastic; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (515 aa)
APUM22Putative pumilio homolog 22; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (361 aa)
APUM10Putative pumilio homolog 10; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (528 aa)
PYM-2Partner of Y14 and mago; Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon- exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs (By similarity). Can increase in vitro the expression from reporter constructs [...] (204 aa)
APUM24Pumilio homolog 24; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (641 aa)
APUM19Putative pumilio homolog 19; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (327 aa)
MPCMaternally expressed PAB C-terminal protein; Encodes almost entirely the C-terminal domain of poly(A)- binding proteins (PABPs). Plays a role in normal seed development and growth. (103 aa)
APUM12Pumilio homolog 12; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (596 aa)
APUM18Pumilio homolog 18; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (327 aa)
GCN2eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 eIF-2- alpha in response to low amino acid availability. Plays a role as an activator of the general amino acid control pathway required for adapatation to amino acid starvation. Converts phosphorylated eIF-2- alpha either to a competitive inhibitor of translation initiation, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a translational initiation activation of specific mR [...] (1241 aa)
APUM21Putative pumilio homolog 21; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (517 aa)
RH12DEAD-box ATP-dependent RNA helicase 12; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (498 aa)
AGO3Protein argonaute 3; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression (By similarity). (1194 aa)
AGO2Protein argonaute 2; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates mainly with siRNAs of 21 nucleotide in length and preferentially recruits small RNAs with a 5' terminal adenosine. Probably involved in antiviral RNA silencing. Associates with siRNA derived from cucumber mosaic virus [...] (1014 aa)
AGO5Protein argonaute 5; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates with siRNAs of various sizes, from 21-24 nucleotide in length and preferentially recruits small RNAs with a 5' terminal cytosine. Probably involved in antiviral RNA silencing. Associates with siRNAs derived from cuc [...] (997 aa)
APUM4Pumilio homolog 4; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. (1003 aa)
MRF4MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 4; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Belongs to the PDCD4 family. (633 aa)
AGO10Protein argonaute 10; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for reliable formation of primary and axillary shoot apical meristems. Specifies leaf adaxial identity by repressing the miR165 and miR166 microRNAs in the embryonic shoot apex, in the shoot apical meristem (SAM) and [...] (988 aa)
APUM20Putative pumilio homolog 20; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (332 aa)
PAB7Polyadenylate-binding protein 7; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity); Belongs to the polyadenylate-binding protein type-1 family. (609 aa)
AGO4Protein argonaute 4; Together with RDM3, required for transcriptional gene silencing (TGS) by DNA methylation and repressive histone modifications (H3K9me2) of several chromatin loci. Component of the RISC complex that associate with the small interfering RNA (siRNA) pathway involved in direct cytosine methylation at endogenous DNA repeats. Forms a AGO4/NRPE1/siRNA complex in cajal body, facilitating its function in RNA-directed gene silencing of target loci. Required for CpNpG and asymmetric DNA methylation as well as histone H3 'Lys-9' methylation (H3K9me) at SUP and SN1 loci. May be [...] (924 aa)
APUM3Pumilio homolog 3; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. (964 aa)
APUM2Pumilio homolog 2; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. (972 aa)
APUM1Pumilio homolog 1; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. (968 aa)
MRF3MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 3; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Involved in the regulation of the ethylene-mediated signaling pathway. Involved in salt stress responses. Reduced cotyledons size and early flowering. (702 aa)
RH8DEAD-box ATP-dependent RNA helicase 8; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (505 aa)
CRP1Pentatricopeptide repeat-containing protein At5g42310, chloroplastic; Required for chloroplast protein synthesis and accumulation of subunits of the thylakoid protein complexes. Activates psaC and petA translation by binding their 5'-UTRs. Required for the correct processing of petB and petD mRNAs. Interacts with the petB and petD intergenic region and is required for the generation of petB and petD monocistronic RNAs; Belongs to the PPR family. P subfamily. (709 aa)
AGO9Protein argonaute 9; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates preferentially with small RNAs of 24 nucleotide in length with a 5' terminal adenosine. Interacts with 24 nucleotide sRNAs derived from transposable elements (TEs). Required to silence pericentrometric-located TEs i [...] (896 aa)
EIF4GEukaryotic translation initiation factor 4G; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Plays a role in the accumulation of some potyvirus during viral infection. Required for the accumulation of cucumber mosaic virus 3a protein and turnip crinkle virus p28 replication protein during viral infection. These proteins are necessary for cell-to-cell movement of the virus. (1727 aa)
APUM14Pumilio homolog 14; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (518 aa)
AGO8Protein argonaute 8; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression (By similarity). (850 aa)
APUM9Pumilio homolog 9; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (564 aa)
PAB5Polyadenylate-binding protein 5; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation; Belongs to the polyadenylate-binding protein type-1 family. (682 aa)
PAB2Polyadenylate-binding protein 2; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Stimulates translation by interaction with translation initiation factor eIF4G, a subunit of the cap-binding complex eIF4F, bringing the 5'- and 3'-ends of the mRNA in proximity. The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiat [...] (629 aa)
F20D21.11Protein translation factor SUI1 homolog 1; Probably involved in translation. (113 aa)
APUM15Pumilio homolog 15; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (444 aa)
SPH17S-protein homolog 17. (136 aa)
EIF(ISO)4G2Eukaryotic translation initiation factor isoform 4G-2; Plays a role in the accumulation of some potyvirus during viral infection. (747 aa)
MRF2MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 2; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. Belongs to the PDCD4 family. (693 aa)
PAB3Polyadenylate-binding protein 3; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Inhibits the polyadenylated RNA degradation by the Rrp41p 3'-->5' exonuclease in vitro. Binds with the 5'UTRs of PAB2, PAB3 and with a lower affinity with the 5'UTR of PAB5. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
AGO6Protein argonaute 6; Involved in transcriptional gene silencing (TGS). Component of the RISC complex that associate with the small interfering RNA (siRNA) pathway involved in direct cytosine methylation at endogenous DNA repeats. Required for the accumulation of specific siRNAs derived from transgene and heterochromatin-related endogenous loci. Involved in RNA-directed DNA methylation (RdDM) at specific endogenous loci. Probably not required for the accumulation of siRNAs derived from transgene inverted repeats that induce post-transcriptional gene silencing (PTGS). Associates mainly w [...] (878 aa)
MAGOProtein mago nashi homolog; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby infl [...] (150 aa)
EIF4E1Eukaryotic translation initiation factor 4E-1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (By similarity); Belongs to the eukaryotic initiation factor 4E family. (235 aa)
PAB4Polyadenylate-binding protein 4; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity). During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp) (By similarity). Belongs to the polyadenylate-binding protein type-1 family. (662 aa)
EIF(ISO)4EEukaryotic translation initiation factor isoform 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Mediates susceptibility to Turnipmosaic potyvirus (TuMV) and Tobacco etch potyvirus (TEV). (198 aa)
AGO1Protein argonaute 1; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Requires DRB1 for directional loading of the small RNA duplex (guide stand and passenger strand) onto RISC for passenger strand degradation. Unlike animal RISC that associates in high molecular weight complex, Arabidopsis RISC i [...] (1048 aa)
PAB6Polyadenylate-binding protein 6; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity); Belongs to the polyadenylate-binding protein type-1 family. (537 aa)
Y14RNA-binding protein Y14; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influen [...] (202 aa)
APUM23Pumilio homolog 23; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (753 aa)
EIF(ISO)4G1Eukaryotic translation initiation factor isoform 4G-1; Plays a role in the accumulation of some potyvirus during viral infection; Belongs to the eukaryotic initiation factor 4G family. (780 aa)
EIF4A3Eukaryotic initiation factor 4A-III homolog; ATP-dependent RNA helicase. Core component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs through [...] (408 aa)
APUM26Pumilio homolog 26; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (187 aa)
MLN51Protein MLN51 homolog; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influenci [...] (605 aa)
MRF1MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 1; Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions. (702 aa)
EIF2AEukaryotic translation initiation factor 2 subunit alpha; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction cataly [...] (344 aa)
T18K17.15Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (513 aa)
APUM7Putative pumilio homolog 7, chloroplastic; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (650 aa)
APUM17Putative pumilio homolog 17; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. (332 aa)
EIF4E3Eukaryotic translation initiation factor 4E-3; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (By similarity). (240 aa)
EIF4E2Eukaryotic translation initiation factor 4E-2; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (By similarity). (240 aa)
AGO7Protein argonaute 7; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for the processing of 21 nucleotide trans-acting siRNAs (ta-siRNAs) derived from TAS3a transcripts. Associates preferentially with the microRNA (miRNA) miR390 which guides the cleavage of TAS3 precursor RNA. Seems to [...] (990 aa)
RH6DEAD-box ATP-dependent RNA helicase 6; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (528 aa)
F20D21.53Protein translation factor SUI1 homolog 2; Probably involved in translation. (113 aa)
DCP5Protein decapping 5; As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor. (611 aa)
TIF3E1Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential). Regulates negatively translation during flower development. (441 aa)
TIF3H1Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential). Regulates translation initiation of specific 5' mRNAs harboring multiple upstream open reading frames (uORFs) in their 5' leader sequence (e.g [...] (337 aa)
APUM6Pumilio homolog 6, chloroplastic; Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2. (861 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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