STRINGSTRING
F20D21.40 F20D21.40 HSP17.6B HSP17.6B T20P8.19 T20P8.19 F9K20.24 F9K20.24 HSP17.6A HSP17.6A PBC1 PBC1 RPT2A RPT2A HSP17.4B HSP17.4B F9M13.6 F9M13.6 HSP26.5 HSP26.5 RPT1A RPT1A RPT1B RPT1B F28O16.14 F28O16.14 RPT2B RPT2B RPN1A RPN1A RPN12A RPN12A RPT3-2 RPT3-2 RPT4A RPT4A RPT5A RPT5A F3F19.7 F3F19.7 F13M14.3 F13M14.3 RPN2B RPN2B RPT4B RPT4B RTM2 RTM2 F5K20_270 F5K20_270 RPN6 RPN6 HSP17.8 HSP17.8 PBE2 PBE2 RPN5A RPN5A RPN12B RPN12B HSP15.7 HSP15.7 HSP23.5 HSP23.5 RPN8B RPN8B RPT6A RPT6A F3N23.32 F3N23.32 HSP23.6 HSP23.6 RPT6B RPT6B RPN7 RPN7 RPN5B RPN5B F28N24.2 F28N24.2 RPN9A RPN9A PBA1 PBA1 PAB2-2 PAB2-2 RPN9B RPN9B PBB2 PBB2 PBG1 PBG1 RPN1B RPN1B T1N15.15 T1N15.15 PAE2-2 PAE2-2 HSP22.0 HSP22.0 ACD32.1 ACD32.1 RPN10 RPN10 PAF1 PAF1 HSP21 HSP21 PAD1 PAD1 HSP17.6 HSP17.6 HSP18.1 HSP18.1 HSP17.4A HSP17.4A HSP17.6C HSP17.6C RCA RCA HSP17.7 HSP17.7 PBC2 PBC2 PAE1-2 PAE1-2 PAC1 PAC1 PAA2-2 PAA2-2 PAA1 PAA1 F13P17.9 F13P17.9 HSP18.5 HSP18.5 HSP15.4 HSP15.4 RPN2A RPN2A PBD2 PBD2 PAD2 PAD2 RPN8A RPN8A PBE1 PBE1 PAG1 PAG1 PBD1 PBD1 PAF2 PAF2 PBB1 PBB1 PAB1-2 PAB1-2 RPT5B RPT5B F22D1.140 F22D1.140 PAC2 PAC2 PA200 PA200 F4IXH9_ARATH F4IXH9_ARATH MTI20.21 MTI20.21
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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F20D21.40HSP20-like chaperones superfamily protein; Belongs to the small heat shock protein (HSP20) family. (183 aa)
HSP17.6B17.6 kDa class I heat shock protein 2; Belongs to the small heat shock protein (HSP20) family. (153 aa)
T20P8.19HSP20-like chaperones superfamily protein; Belongs to the small heat shock protein (HSP20) family. (224 aa)
F9K20.24SecY protein transport family protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
HSP17.6A17.6 kDa class I heat shock protein 1; Possesses chaperone activity. (155 aa)
PBC1Proteasome subunit beta type-3-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (204 aa)
RPT2A26S proteasome regulatory subunit 4 homolog A; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Is required for the maintenance of postembryonic root and shoot meristems. Has a specific role in the regulation of organs size. (443 aa)
HSP17.4B17.4 kDa class III heat shock protein; Belongs to the small heat shock protein (HSP20) family. (155 aa)
F9M13.626S proteasome non-ATPase regulatory subunit-like protein. (84 aa)
HSP26.526.5 kDa heat shock protein, mitochondrial. (232 aa)
RPT1A26S proteasome regulatory subunit 7 homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (426 aa)
RPT1B26S proteasome regulatory subunit 7 homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (464 aa)
F28O16.14HSP20-like chaperones superfamily protein; Belongs to the small heat shock protein (HSP20) family. (244 aa)
RPT2B26S proteasome regulatory subunit 4 homolog B; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (443 aa)
RPN1A26S proteasome non-ATPase regulatory subunit 2 homolog A; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). Required during embryogenesis. Required for optimal plant growth and stress responses. Required for innate immunity. (891 aa)
RPN12A26S proteasome non-ATPase regulatory subunit 8 homolog A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. May help to control the degradation of one or more factors that repress cytokinin signaling. Plays an important role for balancing cell expansion with cell proliferation rates during shoot development. (267 aa)
RPT3-226S proteasome regulatory subunit 6B homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (408 aa)
RPT4A26S proteasome regulatory subunit 10B homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (399 aa)
RPT5A26S proteasome regulatory subunit 6A homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Plays a essential role in the gametophyte development. (424 aa)
F3F19.7Proline-rich receptor-like kinase. (317 aa)
F13M14.3HSP20-like chaperones superfamily protein; Belongs to the small heat shock protein (HSP20) family. (490 aa)
RPN2B26S proteasome non-ATPase regulatory subunit 1 homolog B; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1001 aa)
RPT4B26S proteasome regulatory subunit S10B homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (399 aa)
RTM2Protein RESTRICTED TEV MOVEMENT 2; Required for the restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance. Seems to not be involved in heat resistance. (366 aa)
F5K20_270Probable proteasome inhibitor; Could play an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome (By similarity); Belongs to the proteasome inhibitor PI31 family. (302 aa)
RPN626S proteasome non-ATPase regulatory subunit 11 homolog; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6A is required for proteasome assembly (By similarity). (419 aa)
HSP17.817.8 kDa class I heat shock protein; Cytosolic mediator for sorting and targeting of nascent chloroplast outer envelope membrane (OEM) proteins to the chloroplast. Functions as a AKR2A cofactor to facilitates the targeting of OEP7 to chloroplasts; Belongs to the small heat shock protein (HSP20) family. (157 aa)
PBE2Proteasome subunit beta type-5-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (273 aa)
RPN5A26S proteasome non-ATPase regulatory subunit 12 homolog A; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Required for gametogenesis and sporophyte development. Acts redundantly with RPN5B. (442 aa)
RPN12BPutative 26S proteasome non-ATPase regulatory subunit 8 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (233 aa)
HSP15.715.7 kDa heat shock protein, peroxisomal; Possesses chaperone activity; Belongs to the small heat shock protein (HSP20) family. (137 aa)
HSP23.523.5 kDa heat shock protein, mitochondrial; Belongs to the small heat shock protein (HSP20) family. (210 aa)
RPN8B26S proteasome non-ATPase regulatory subunit 7 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (310 aa)
RPT6A26S proteasome regulatory subunit 8 homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (419 aa)
F3N23.32P-loop containing nucleoside triphosphate hydrolases superfamily protein. (432 aa)
HSP23.623.6 kDa heat shock protein, mitochondrial; Belongs to the small heat shock protein (HSP20) family. (210 aa)
RPT6B26S proteasome regulatory subunit 8 homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (419 aa)
RPN726S proteasome non-ATPase regulatory subunit 6 homolog; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (387 aa)
RPN5B26S proteasome non-ATPase regulatory subunit 12 homolog B; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). Acts redundantly with RPN5A. (442 aa)
F28N24.2SecY protein transport family protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
RPN9A26S proteasome non-ATPase regulatory subunit 13 homolog A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (386 aa)
PBA1Proteasome subunit beta type-6; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (233 aa)
PAB2-2Proteasome subunit alpha type-2-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (235 aa)
RPN9B26S proteasome non-ATPase regulatory subunit 13 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (386 aa)
PBB2Proteasome subunit beta type-7-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (274 aa)
PBG1Proteasome subunit beta type-4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (246 aa)
RPN1B26S proteasome non-ATPase regulatory subunit 2 homolog B; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (891 aa)
T1N15.15Proteasome inhibitor-like protein. (175 aa)
PAE2-2Proteasome subunit alpha type-5-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (237 aa)
HSP22.022.0 kDa heat shock protein. (195 aa)
ACD32.1Peroxisomal small heat shock protein Acd31.2; Belongs to the small heat shock protein (HSP20) family. (285 aa)
RPN1026S proteasome non-ATPase regulatory subunit 4 homolog; Plays a role in maintaining the structural integrity of the 19S regulatory particle (RP), subcomplex of the 26S proteasome. Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a potential docking subunit for both ubiquitin receptors RAD23s and [...] (386 aa)
PAF1Proteasome subunit alpha type-1-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Negatively regulates thiol biosynthesis and arsenic tolerance. (278 aa)
HSP21Heat shock protein 21, chloroplastic; Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. Belongs to the small heat shock protein (HSP20) family. (227 aa)
PAD1Proteasome subunit alpha type-7-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the association of the SCF(TIR1) E3 ubiquitin ligase complex with the proteasome. (250 aa)
HSP17.617.6 kDa class II heat shock protein; Belongs to the small heat shock protein (HSP20) family. (155 aa)
HSP18.118.1 kDa class I heat shock protein. (161 aa)
HSP17.4A17.4 kDa class I heat shock protein. (156 aa)
HSP17.6C17.6 kDa class I heat shock protein 3; Belongs to the small heat shock protein (HSP20) family. (157 aa)
RCARibulose bisphosphate carboxylase/oxygenase activase, chloroplastic; Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure. (474 aa)
HSP17.717.7 kDa class II heat shock protein; Belongs to the small heat shock protein (HSP20) family. (156 aa)
PBC2Proteasome subunit beta type-3-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (204 aa)
PAE1-2Proteasome subunit alpha type-5-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (237 aa)
PAC1Proteasome subunit alpha type-4-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (250 aa)
PAA2-2Proteasome subunit alpha type-6-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (246 aa)
PAA1Proteasome subunit alpha type-6-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (246 aa)
F13P17.9SecY protein transport family protein; Belongs to the SecY/SEC61-alpha family. (475 aa)
HSP18.518.5 kDa class IV heat shock protein; Belongs to the small heat shock protein (HSP20) family. (162 aa)
HSP15.415.4 kDa class V heat shock protein; Belongs to the small heat shock protein (HSP20) family. (134 aa)
RPN2A26S proteasome non-ATPase regulatory subunit 1 homolog A; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1004 aa)
PBD2Proteasome subunit beta type-2-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (199 aa)
PAD2Proteasome subunit alpha type-7-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (250 aa)
RPN8A26S proteasome non-ATPase regulatory subunit 7 homolog A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). Required for innate immunity. (308 aa)
PBE1Proteasome subunit beta type-5-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (274 aa)
PAG1Proteasome subunit alpha type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (249 aa)
PBD1Proteasome subunit beta type-2-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (204 aa)
PAF2Proteasome subunit alpha type-1-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May play a role in thiol biosynthesis and arsenic tolerance in association with PAF1/ARS5. (277 aa)
PBB1Proteasome subunit beta type-7-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (273 aa)
PAB1-2Proteasome subunit alpha type-2-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (235 aa)
RPT5B26S proteasome regulatory subunit 6A homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (423 aa)
F22D1.140HSP20-like chaperones superfamily protein; Belongs to the small heat shock protein (HSP20) family. (249 aa)
PAC2Putative proteasome subunit alpha type-4-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family. (208 aa)
PA200Proteasome activator subunit 4; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin- independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA d [...] (1811 aa)
F4IXH9_ARATHARM repeat superfamily protein. (551 aa)
MTI20.2126S proteasome regulatory subunit. (256 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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