STRINGSTRING
PP2A2-2 PP2A2-2 DSP1 DSP1 FAD4 FAD4 PSAL PSAL TRN1-2 TRN1-2 DSP5 DSP5 DSP4 DSP4 emb2004 emb2004 T21H19.130 T21H19.130 DSP2 DSP2 DSP3 DSP3 PP2AA3 PP2AA3 PP2AA2 PP2AA2 PP2AA1 PP2AA1 PP2A3 PP2A3 PP2A1-2 PP2A1-2 F4JC80_ARATH F4JC80_ARATH FAD4L1 FAD4L1 PP2A5 PP2A5 FAD4L2 FAD4L2 PP2A4 PP2A4 RPS27AB RPS27AB RPS27AC RPS27AC RPS27AA RPS27AA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
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PP2A2-2Serine/threonine-protein phosphatase PP2A-2 catalytic subunit; Dephosphorylates and activates the actin-depolymerizing factor ADF1, which, in turn, regulates actin cytoskeleton remodeling and is involved in the blue light photoreceptor PHOT2-mediated chloroplast avoidance movements. Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Acts as negative regulator of abscisic acid (ABA) signaling. May r [...] (306 aa)
DSP1Tyrosine-protein phosphatase DSP1; Possesses phosphotyrosine phosphatase activity in vitro. Hydrolyzes para-nitrophenyl phosphate in vitro. Hydrolyzes O-methylfluorescein phosphate in vitro. Hydrolyzes polyphosphate and ATP in vitro. Dephosphorylates the phosphoinositides PI(3,4,5)P3, PI(3,5)P2, but not PI(3)P, PI(3,4)P2 or PI(4,5)P2. Belongs to the protein-tyrosine phosphatase family. (215 aa)
FAD4Fatty acid desaturase 4, chloroplastic; Fatty acid desaturase involved in the production of chloroplast-specific phosphatidylglycerol molecular species containing 16:1(3E). Catalyzes the formation of a trans double bond introduced close to the carboxyl group of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol. (323 aa)
PSALPhotosystem I reaction center subunit XI, chloroplastic; Belongs to the PsaL family. (219 aa)
TRN1-2Protein TORNADO 1; Involved in the basipetal transport of auxin (IAA) that modulates growth and organs organization. Required for initial divisions in the epidermal/lateral root cap leading to the formation of epidermal cells and a clone of lateral root cap cells, as well as for the maintenance of the radial pattern of cell specification in the root, thus regulating the distinction between the lateral root cap and epidermis. (1380 aa)
DSP5Tyrosine-protein phosphatase DSP5; Possesses low phosphotyrosine phosphatase activity in vitro. Hydrolyzes O-methylfluorescein phosphate in vitro. Dephosphorylates the phosphoinositides PI(3,5)P2. (204 aa)
DSP4Probable tyrosine-protein phosphatase DSP4; Probable tyrosine-protein phosphatase that acts as negative regulator of defense responses against the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000. (198 aa)
emb2004RNI-like superfamily protein. (605 aa)
T21H19.130HEAT repeat-containing protein. (1180 aa)
DSP2Tyrosine-protein phosphatase DSP2; Possesses phosphotyrosine phosphatase activity in vitro. Hydrolyzes para-nitrophenyl phosphate in vitro. Hydrolyzes O-methylfluorescein phosphate in vitro. Dephosphorylates the phosphoinositides PI(3,5)P2. (257 aa)
DSP3Tyrosine-protein phosphatase DSP3; Possesses phosphotyrosine phosphatase activity in vitro. Hydrolyzes para-nitrophenyl phosphate in vitro. Hydrolyzes O-methylfluorescein phosphate in vitro. Dephosphorylates the phosphoinositides PI(3,5)P2. (203 aa)
PP2AA3Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform; The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Involved during developmental process such as seedling and floral developments. Seems to act as a negative regulator of PP2A catalytic activity. (587 aa)
PP2AA2Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Involved during developmental process such as seedling and floral developments. Seems to act as a negative regulator of PP2A catalytic activity. Associates with the serine/threonine-protein phosphatase PP2A catalytic subunit C and regulatory subunit B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosp [...] (587 aa)
PP2AA1Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Seems to act as a positive regulator of PP2A catalytic activity. Confers resistance to phosphatase inhibitors such as okadaic acid and cantharidin. Involved during developmental process such as seedling and floral developments, root gravitropism, and stomatal opening regulation. Involved in the regulation of auxin efflux, especially during basip [...] (588 aa)
PP2A3Serine/threonine-protein phosphatase PP2A-3 catalytic subunit; Functions redundantly with PP2A4, and is involved in establishing auxin gradients, apical-basal axis of polarity and root and shoot apical meristem during embryogenesis. May dephosphorylate PIN1 and regulate its subcellular distribution for polar auxin transport. Involved in the regulation of formative cell division in roots by dephosphorylating ACR4 protein kinase. (313 aa)
PP2A1-2Serine/threonine-protein phosphatase PP2A-1 catalytic subunit; Belongs to the PPP phosphatase family. PP-2A subfamily. (306 aa)
F4JC80_ARATHWW domain-containing protein. (892 aa)
FAD4L1Fatty acid desaturase 4-like 1, chloroplastic; Fatty acid desaturase involved in the production of chloroplast-specific phosphatidylglycerol molecular species. Catalyzes the formation of a trans double bond introduced close to the carboxyl group of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol (By similarity). (295 aa)
PP2A5Serine/threonine-protein phosphatase PP2A-5 catalytic subunit; Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Involved in the positive regulation of salt stress responses. May function by increasing chloride channel activities on vacuolar membranes. (307 aa)
FAD4L2Fatty acid desaturase 4-like 2, chloroplastic; Fatty acid desaturase involved in the production of chloroplast-specific phosphatidylglycerol molecular species. Catalyzes the formation of a trans double bond introduced close to the carboxyl group of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol (By similarity). (279 aa)
PP2A4Serine/threonine-protein phosphatase PP2A-4 catalytic subunit; Functions redundantly with PP2A3, and is involved in establishing auxin gradients, apical-basal axis of polarity and root and shoot apical meristem during embryogenesis. May dephosphorylate PIN1 and regulate its subcellular distribution for polar auxin transport. The holoenzyme composed of PP2AA1, PP2A4 and B'ZETA or B'ETA acts as negative regulator of plant innate immunity by controlling BAK1 phosphorylation state and activation in surface- localized immune receptor complexes. Belongs to the PPP phosphatase family. PP-2A s [...] (313 aa)
RPS27ABUbiquitin-40S ribosomal protein S27a-2; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
RPS27ACUbiquitin-40S ribosomal protein S27a-3; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
RPS27AAUbiquitin-40S ribosomal protein S27a-1; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (156 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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