STRINGSTRING
RPS27AB RPS27AB SPX2 SPX2 WNK5 WNK5 F3I6.24 F3I6.24 F17L21.22 F17L21.22 A8MSG2_ARATH A8MSG2_ARATH F3N23.22 F3N23.22 DHAR1 DHAR1 T16B5.6 T16B5.6 WNK3 WNK3 F18O14.31 F18O14.31 WNK4 WNK4 RPS27AA RPS27AA RPS27AC RPS27AC CLC-G CLC-G AATP2 AATP2 CLC-A CLC-A CLC-B CLC-B CLC-D CLC-D WNK9 WNK9 AATP1 AATP1 SPX3 SPX3 CLPF CLPF WNK11 WNK11 BHLH157 BHLH157 CLC-E CLC-E Q8GXU7_ARATH Q8GXU7_ARATH SPX1 SPX1 DHAR3 DHAR3 WNK7 WNK7 WNK10 WNK10 CLC-F CLC-F WNK6 WNK6 WNK2 WNK2 F7H19.170 F7H19.170 WNK8 WNK8 SPX4 SPX4 Q94K36_ARATH Q94K36_ARATH CLC-C CLC-C WNK1 WNK1 DHAR4 DHAR4 OFP13 OFP13 EXA1 EXA1 DHAR2 DHAR2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
RPS27ABUbiquitin-40S ribosomal protein S27a-2; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
SPX2SPX domain-containing protein 2; May inhibit PHR1 DNA-binding activity in a Pi-dependent manner. (287 aa)
WNK5Probable serine/threonine-protein kinase WNK5; Regulates flowering time by modulating the photoperiod pathway; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. (549 aa)
F3I6.24GYF domain-containing protein. (1495 aa)
F17L21.22GYF domain-containing protein. (1492 aa)
A8MSG2_ARATHSerine/threonine-protein kinase WNK (With No Lysine)-like protein. (79 aa)
F3N23.22Anoctamin-like protein At1g73020; May act as a calcium-activated chloride channel. Belongs to the anoctamin (TC 1.A.17) family. (665 aa)
DHAR1Glutathione S-transferase DHAR1, mitochondrial; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses, subsequently to biotic or abiotic inducers. As a peripheral membrane protein, could also function as voltage-gated ion channel. Belongs to the GST superfamily. DHAR family. (213 aa)
T16B5.6Voltage-gated hydrogen channel-like protein. (236 aa)
WNK3Probable serine/threonine-protein kinase WNK3; May regulate flowering time by modulating the photoperiod pathway. (516 aa)
F18O14.31Glutathione S-transferase family protein. (153 aa)
WNK4Probable serine/threonine-protein kinase WNK4; May regulate flowering time by modulating the photoperiod pathway; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. (571 aa)
RPS27AAUbiquitin-40S ribosomal protein S27a-1; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (156 aa)
RPS27ACUbiquitin-40S ribosomal protein S27a-3; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
CLC-GPutative chloride channel-like protein CLC-g; Putative voltage-gated chloride channel. (765 aa)
AATP2ADP,ATP carrier protein 2, chloroplastic. (618 aa)
CLC-AChloride channel protein CLC-a; Voltage-gated chloride channel that could play a role in the regulation of nitrate content. (775 aa)
CLC-BChloride channel protein CLC-b; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (780 aa)
CLC-DChloride channel protein CLC-d; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (792 aa)
WNK9Probable serine/threonine-protein kinase WNK9; May regulate flowering time by modulating the photoperiod pathway; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. (492 aa)
AATP1ADP,ATP carrier protein 1, chloroplastic; May function as an ATP importer. Belongs to the ADP/ATP translocase tlc (TC 2.A.12.2) family. (624 aa)
SPX3SPX domain-containing protein 3; Plays a positive role in plant adaptation to phosphate starvation and exerts negative feedback regulation of SPX1. (245 aa)
CLPFClp protease adapter protein ClpF, chloroplastic; Clp protease adapter that facilitates CLPS1 recruitment to ClpC chaperones thus forming a binary adapter for selective substrate recognition and delivery to plastid Clp protease system (CLPC). (330 aa)
WNK11Probable serine/threonine-protein kinase WNK11; May regulate flowering time by modulating the photoperiod pathway. (314 aa)
BHLH157Transcription factor bHLH157; Transcription factor that may regulate root development. (527 aa)
CLC-EChloride channel protein CLC-e; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (710 aa)
Q8GXU7_ARATHAt4g13612. (71 aa)
SPX1SPX domain-containing protein 1; Plays a positive role in plant adaptation to phosphate starvation. Inhibits PHR1 DNA-binding activity in a Pi-dependent manner. (256 aa)
DHAR3Glutathione S-transferase DHAR3, chloroplastic; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses (By similarity). (258 aa)
WNK7Probable serine/threonine-protein kinase WNK7; May regulate flowering time by modulating the photoperiod pathway. (557 aa)
WNK10Probable serine/threonine-protein kinase WNK10; May regulate flowering time by modulating the photoperiod pathway. (524 aa)
CLC-FChloride channel protein CLC-f; Voltage-gated chloride channel. (781 aa)
WNK6Probable serine/threonine-protein kinase WNK6; May regulate flowering time by modulating the photoperiod pathway. (567 aa)
WNK2Serine/threonine-protein kinase WNK2; Regulates flowering time by modulating the photoperiod pathway. Possesses kinase activity in vitro. (568 aa)
F7H19.170SPX domain-containing membrane protein At4g22990; Belongs to the major facilitator superfamily. (699 aa)
WNK8Serine/threonine-protein kinase WNK8; Regulates flowering time by modulating the photoperiod pathway. Phosphorylates the vacuolar ATPase subunit C (VATC) and RGS1. Regulates EDM2 that, in turn, modulates development processes. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. (563 aa)
SPX4SPX domain-containing protein 4. (318 aa)
Q94K36_ARATHUncharacterized protein family SERF. (69 aa)
CLC-CChloride channel protein CLC-c; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (779 aa)
WNK1Serine/threonine-protein kinase WNK1; Regulates flowering time by modulating the photoperiod pathway. Phosphorylates APRR3. (700 aa)
DHAR4Probable glutathione S-transferase DHAR4; Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. (217 aa)
OFP13Transcription repressor OFP13; Transcriptional repressor that regulates multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors. (260 aa)
EXA1Protein ESSENTIAL FOR POTEXVIRUS ACCUMULATION 1; Translational repressor involved in the negative regulation of immune receptor accumulation via the inhibition of nucleotide- binding leucine-rich repeat (NLR) receptor mediated defense. Represses NLR protein accumulation (e.g. SNC1, RPS4, RPM1 and RPS2). Together with SMG7, helps to restrict effector-triggered immunity (ETI) cell death induction during pathogen infection in a salicylic acid- (SA) and reactive oxygen species- (ROS) independent manner. Required for pathogen-associated molecular pattern (PAMP)-induced suppression of necrot [...] (1714 aa)
DHAR2Glutathione S-transferase DHAR2; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses. Plays a role in ozone tolerance; Belongs to the GST superfamily. DHAR family. (213 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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